The Journal of Pediatric Academy最新文献_第3页

Is There a Relationship Between Vitamin D Level and Iron Deficiency Anemia in Children? 儿童维生素D水平与缺铁性贫血有关系吗?

The Journal of Pediatric Academy Pub Date : 2023-03-31 DOI: 10.4274/jpea.2023.202

Emine Özdemir Kaçer, C. Kılıçaslan

{"title":"Is There a Relationship Between Vitamin D Level and Iron Deficiency Anemia in Children?","authors":"Emine Özdemir Kaçer, C. Kılıçaslan","doi":"10.4274/jpea.2023.202","DOIUrl":"https://doi.org/10.4274/jpea.2023.202","url":null,"abstract":"Iron deficiency anemia (IDA) is the most common type of anemia in children and a major cause of morbidity and mortality. VitaminD deficiency (VDD) is a growing public health issue that has been connected to several chronic diseases, such as osteoporosis,cancer, and metabolic syndrome. Recently, in a meta-analytic study conducted on both children and adults, it was clearly shownthat there is a relationship between VDD and the risk of anemia. In this study, we wanted to review the prevalence of vitamin Dinsufficiency in children with IDA. We conducted a retrospective review of patient records from January 2017 to December 2019 toidentify individuals aged 4 months to 18 years who had been diagnosed with IDA. Demographic data, dietary patterns, nutritionalsupplements, Vitamin D levels, and laboratory tests were recorded. Two hundred thirty girls and 198 boys were enrolled in thestudy, bringing the total number of patients to 428. The patients had a mean age of 7.24±5.1 months. The distribution of femalegender according to vitamin D groups (normal, insufficient, deficient) was 85, 103, and 42, respectively; the male gender is 78,89, and 31, respectively (p=0.745). No statistically significant difference was found between nutrition categories and vitamin Dgroups in different age groups (p=0.293; p=0.238; p=0.396). No statistically significant difference was found between continuousquantitative variables such as age, hemoglobin, and ferritin and vitamin D groups in different age groups (p=0.885; p=0.168;p=0.728). There was no significant association observed between the severity of anemia and VDD in children with IDA in our study.In the diagnosis of IDA, it may be useful to look at vitamin D levels by considering the time of admission. Further studies are neededfor the association between vitamin D levels and IDA.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127326927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Assessment of Hypertension in Children with Autosomal Dominant Polycystic Kidney Disease; Single-Center Experience 常染色体显性多囊肾病患儿高血压的评价单中心经验

The Journal of Pediatric Academy Pub Date : 2023-03-31 DOI: 10.4274/jpea.2023.199

Alper Uygun, H. Nalcacioglu, O. Aydog

{"title":"Assessment of Hypertension in Children with Autosomal Dominant Polycystic Kidney Disease; Single-Center Experience","authors":"Alper Uygun, H. Nalcacioglu, O. Aydog","doi":"10.4274/jpea.2023.199","DOIUrl":"https://doi.org/10.4274/jpea.2023.199","url":null,"abstract":"Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common hereditary renal cystic diseases. Althoughits clinical manifestations usually occur in adulthood, hypertension (HT) is known to develop in most patients before the decline inrenal function and it is associated with faster progression to end stage kidney disease (ESKD). We investigated ambulatory bloodpressure monitoring (ABPM) results of 23 patients with ADPKD, followed up in the Pediatric Nephrology Clinic of Ondokuz MayısUniversity Medical Faculty Hospital. Patients’ demographic characteristics, laboratory and ultrasonography (US) results, officeblood pressure, and ABPM measurements were evaluated. The parameters of gender, age, increased kidney size, proteinuria,glomerular filtration rate (GFR) was compared in hypertensive and non-hypertensive group. Twenty three patients (13 girls, tenboys) with a mean age of 11.94±4.01 (min-max: 4.6-18) years and a female/male ratio of 1.3/1 were examined. Ultrasound revealedincreased kidney sizes in 12 patients (52.2%) and multiple cysts in the bilateral kidneys in 20 patients (87%). Mild to moderateproteinuria was detected in 7 patients (30.4%). The HT ratio of patients was 52.2% and 39.1% when assessed with office bloodpressure (BP) measurement and ABPM respectively. A non-dipper pattern was established in 14 patients (60.9%). Gender, age,increased kidney size, proteinuria, GFR did not differ significantly between ADPKD patients with and without ambulatory HT. Thisstudy shows that nearly half of children with ADPKD have HT by ABPM. BP should be regularly screened by ABPM in all pediatricADPKD patients.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130147159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inherited Bone Marrow Failure Syndromes in Children 儿童遗传性骨髓衰竭综合征

The Journal of Pediatric Academy Pub Date : 2023-03-31 DOI: 10.4274/jpea.2023.218

Mehmet Emin Ertunç, Ahmet Genar Çelik, Akif Tahiroğlu, Ekrem Ünal

引用次数: 0

Vitamin D, Insulin Resistance and Cytokine Levels in Obese Pubertal Children 青春期肥胖儿童的维生素D、胰岛素抵抗和细胞因子水平

The Journal of Pediatric Academy Pub Date : 2023-03-31 DOI: 10.4274/jpea.2023.213

Serap Kirkiz Kayalı, P. Cinaz, A. Bideci

{"title":"Vitamin D, Insulin Resistance and Cytokine Levels in Obese Pubertal Children","authors":"Serap Kirkiz Kayalı, P. Cinaz, A. Bideci","doi":"10.4274/jpea.2023.213","DOIUrl":"https://doi.org/10.4274/jpea.2023.213","url":null,"abstract":"Insulin resistance (IR) develops in obese children because of low vitamin levels and increased pro-inflammatory cytokine levels.This study aimed to analyze the relation between vitamin D, insulin resistance, tumor necrosis factor-alpha and interleukin 6 (IL-6)levels at admission and after weight loss. This study included 84 obese and 28 healthy pubertal children. Patient group was dividedinto four: IR positive and negative; weight loss (WL) positive and negative. Baseline and follow-up (6th month) values of serum25-hydroxyvitamin D and other parameters were evaluated. The prevalence of serum vitamin D deficiency and insufficiency were3.6% and 21.4% in the control group, 15.2% and 10.9% and 7.9% and 15.8% in the obese insulin positive and negative group;respectively. There was no relationship between vitamin D and IRand IL-6 levels, whereas cytokine levels were lower in obesechildren. As WL increased, vitamin D level and IR improved. No significant difference was found between vitamin D levels of obeseand control subjects. In obese children with weight loss, an insignificant increase was observed in vitamin D, cytokines, quantitativeinsulin sensitivity check index values and an insignificant decrease was noted in homeostatic model assessment for IR value.Further longitudinal studies with larger patient series with greater WL are warranted.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133810638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between Dyspnea Severity with Radiological and Laboratory Findings in Pneumonia in Children in Pediatric Palliative Care 小儿姑息治疗中肺炎患儿呼吸困难严重程度与影像学和实验室检查结果的关系

The Journal of Pediatric Academy Pub Date : 2023-03-31 DOI: 10.4274/jpea.2023.198

Nilgün Harputluoğlu, M. Coşkun, D. Çubukçu, T. Çelik

{"title":"The Relationship Between Dyspnea Severity with Radiological and Laboratory Findings in Pneumonia in Children in Pediatric Palliative Care","authors":"Nilgün Harputluoğlu, M. Coşkun, D. Çubukçu, T. Çelik","doi":"10.4274/jpea.2023.198","DOIUrl":"https://doi.org/10.4274/jpea.2023.198","url":null,"abstract":"In care patients; pneumonia is common due to being bedridden, atrophy of respiratory muscles and use of medical devices.Dyspnea is the second most common symptom after pain in pediatric palliative care. In this study, it was aimed to examine therelationship between the severity of dyspnea and pneumonia. The study is a study that included patients admitted to pediatricpalliative care, diagnosed with pneumonia, and applied Modified Borg Scale (MBS) between December 15, 2019 and December15, 2020. The MBS has a scoring system ranging from 0 to 10 and assesses the severity of dyspnea. A total of 72 (34.4%) patientsdiagnosed with pneumonia and underwent MBS were included in the study. 51.4% (n=37) of the study group were male, and themedian age was 6.00 years (ranges of quarters=9). It was observed that the severity of dyspnea did not affect determining thepneumonia type and possible pathogen (p=0.613, p=0.948, respectively) In line with the results of the study, it can be concludedthat there is no relationship between the severity of dyspnea and pneumonia in patients in need of care.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130905853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case of Pediatric Urticaria Pigmentosa 小儿色素荨麻疹1例

The Journal of Pediatric Academy Pub Date : 2023-03-31 DOI: 10.4274/jpea.2023.201

Şevkiye Aydoğdu, İbrahim Halil Aydoğdu

引用次数: 0

Exfoliative Cheilitis in Childhood: A Successful Treatment with Tacrolimus 儿童剥脱性唇腭裂:他克莫司成功治疗

The Journal of Pediatric Academy Pub Date : 2023-03-31 DOI: 10.4274/jpea.2023.193

Emel Ulusoy, A. Abacı

引用次数: 0

The Predictors of Pneumonia in Children with COVID-19 COVID-19患儿肺炎的预测因素

The Journal of Pediatric Academy Pub Date : 2023-03-31 DOI: 10.4274/jpea.2023.200

M. A. Yoldaş, A. Tayfur, Ayşegül Danış, Fatma Hancı, H. Atasoy, S. Bolu, Zeliha Coşgun, M. E. Kalfaoğlu, S. A. Kayış

{"title":"The Predictors of Pneumonia in Children with COVID-19","authors":"M. A. Yoldaş, A. Tayfur, Ayşegül Danış, Fatma Hancı, H. Atasoy, S. Bolu, Zeliha Coşgun, M. E. Kalfaoğlu, S. A. Kayış","doi":"10.4274/jpea.2023.200","DOIUrl":"https://doi.org/10.4274/jpea.2023.200","url":null,"abstract":"The purpose of this study was to evaluate the relationship between the presence of pneumonia and blood parameters in casesof Coronavirus disease (COVID-19) and to examine their predictive characteristics in terms of pneumonia. We reviewed the filerecords of 151 pediatric patients with a diagnosis of COVID-19 confirmed by the real time-reverse transcription polymerase chainreaction test in nasopharyngeal swabs. The patients were divided into two groups based on direct chest X-ray and computedtomography results in [Group 1 (n:41), with pneumonia findings, and Group 2 (n:110), with no pneumonia findings]. The groups’demographic data, clinical and laboratory findings were compared. Pulmonary involvement was determined in 41 (27.1%) ofthe 151 patients. The [body mass index (BMI) Z-score], red blood cell distribution width (RDW), mean platelet volume (MPV),neutrophil lymphocyte ratio, passive leg raise, and D-dimer levels were significantly higher in patients with pneumonia than thosewithout pneumonia in our study. Based on multivariate logistic regression analysis, BMI Z-score, MPV, and RDW were found tobe independent risk factors of pneumonia in patients. The current study showed higher levels of blood parameters in patients withcoronavirus disease 2019 (COVID -19) presenting with pneumonia than those without pneumonia. We suggest that BMI-Z scoreand MPV value may assist in predicting pulmonary involvement in patients with COVID-19.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128380654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Thiol/Disulfide Homeostasis and Neurogenin 3 Levels as a Marker of Oxidative Stress in Children and Adolescents Newly Diagnosed with Type 1 Diabetes 新诊断为1型糖尿病的儿童和青少年中硫醇/二硫体内平衡和神经原素3水平作为氧化应激标志物的评估

The Journal of Pediatric Academy Pub Date : 2022-12-23 DOI: 10.51271/jpea-2022-195

Gözde Deliktaş, Reyhan Deveci Sevim, Tolga Ünüvar

{"title":"Evaluation of Thiol/Disulfide Homeostasis and Neurogenin 3 Levels as a Marker of Oxidative Stress in Children and Adolescents Newly Diagnosed with Type 1 Diabetes","authors":"Gözde Deliktaş, Reyhan Deveci Sevim, Tolga Ünüvar","doi":"10.51271/jpea-2022-195","DOIUrl":"https://doi.org/10.51271/jpea-2022-195","url":null,"abstract":"The objective of the study was to determine the relationship between autoimmunity and dynamic thiol/disulfide, neurogenin 3 (ngn 3) status in the newly diagnosed with type 1 diabetes mellitus (T1DM), the level of treatment, and thiol/disulfide homeostasis and neurogenin 3, and to found the changes in neurogenin 3 level due to beta cell damage in children newly diagnosed with T1DM. Totally 60 children aged 1-18 years old, 30 of them newly diagnosed with type 1 diabetes (patients), and 30 of them healthy children in the same age group (control) were included in the study. Insulin and C-peptide levels of newly diagnosed T1DM patients were lower than the control group, however, HbA1c, glucose, creatinine, cholesterol, triglyceride, and LDL levels were found higher in patients. Total thiol level and Gad antibody positive rate were found higher in children newly diagnosed with T1DM. In addition, it was observed that the rate of anti-insulin antibody positivity increased in the 6th-month control of patients. However, HbA1c and glucose levels at diagnosis were higher in patients compared to the control group at the sixth month. Insulin and C-peptide levels were determined lower in patients admitted with diabetic ketoacidosis. A negative correlation was observed between native thiol and anti-insulin antibody parameters and a positive correlation between ngn 3 and total cholesterol and LDL. In conclusion, thiol/disulfide homeostasis and ngn 3 parameters can be used as oxidative stress markers in children and adolescents newly diagnosed with T1DM.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"125 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124732370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nephrotic syndrome in a patient with Glycogen Storage Disease Type IXb. 糖原储存病IXb型肾病综合征1例。

The Journal of Pediatric Academy Pub Date : 2022-12-23 DOI: 10.51271/jpea-2022-192

Merve Yoldaş Çelik, H. Yazıcı, Fehime Erdem, E. Canda, Banu Sarsik Kumbaraci, İpek Kaplan Bulut, S. Kalkan Uçar, S. Kabasakal, M. Çoker

引用次数: 0