European Heart Journal - Quality of Care and Clinical Outcomes最新文献

{"title":"Women with acute and chronic myocardial ischaemia have worse early results after PTCA and CABG, but better 1-year results.","authors":"Antonio V Sterpetti, Monica Campagnol, Raimondo Gabriele","doi":"10.1093/ehjqcco/qcae046","DOIUrl":"10.1093/ehjqcco/qcae046","url":null,"abstract":"","PeriodicalId":11869,"journal":{"name":"European Heart Journal - Quality of Care and Clinical Outcomes","volume":" ","pages":"763"},"PeriodicalIF":4.8,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141317122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The state of adult congenital heart disease training from the trainee perspective: a call for action.","authors":"Panagiota Mitropoulou, Petra Jenkins, C Fielder Camm, Konstantinos Dimopoulos, Andrew Constantine","doi":"10.1093/ehjqcco/qcae029","DOIUrl":"10.1093/ehjqcco/qcae029","url":null,"abstract":"","PeriodicalId":11869,"journal":{"name":"European Heart Journal - Quality of Care and Clinical Outcomes","volume":" ","pages":"653-655"},"PeriodicalIF":4.8,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140848645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Embracing the promise of patient reported outcome measures in cardiology.","authors":"Chris Wilkinson, Asad Bhatty, Adam B Smith, Jeremy Dwight, Julie Sanders, Chris P Gale","doi":"10.1093/ehjqcco/qcae073","DOIUrl":"10.1093/ehjqcco/qcae073","url":null,"abstract":"","PeriodicalId":11869,"journal":{"name":"European Heart Journal - Quality of Care and Clinical Outcomes","volume":" ","pages":"651-652"},"PeriodicalIF":4.8,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of multiple risk factor control level on cardiovascular outcomes in hypertensive patients.","authors":"Xinyi Peng, Miaomiao Zhuang, Qirui Song, Jingjing Bai, Jun Cai","doi":"10.1093/ehjqcco/qcae056","DOIUrl":"10.1093/ehjqcco/qcae056","url":null,"abstract":"<p><strong>Aims: </strong>The relationship between the level of baseline risk factor control and cardiovascular outcomes in hypertensive patients with blood pressure interventions is not well understood. It is also unclear whether the level of baseline risk factor control is persuasively associated with cardiovascular outcomes in hypertensive patients with a blood pressure lowering strategy.</p><p><strong>Method and results: </strong>We performed an analysis of the Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients (STEP) trial. Participants without complete baseline risk factor data were excluded. The primary outcome was a composite of cardiovascular events and all-cause mortality. Cox proportional hazard models were used to calculate the hazard ratio (HR) and estimate the association between risk factor control levels (≥6, 5, 4, and ≤3) and cardiovascular outcomes. A total of 8337 participants were involved in the analysis, and the median follow-up period was 3.19 years. Each additional risk factor uncontrolled was associated with a 24% higher cardiovascular risk (HR 1.24, 95% CI 1.11-1.37). Compared with participants with optimal risk factor control, those with ≤3 factors control exhibited 95% higher cardiovascular risk (HR 1.95, 95% CI 1.37-2.77). The corresponding protective effects of multiple risk factor modification were not influenced by intensive or standard antihypertensive treatment (P for interaction = 0.71).</p><p><strong>Conclusion: </strong>A stepwise association was observed between cardiovascular risk and the number of risk factor control in hypertensive patients. The more risk factors were modified, the less cardiovascular risk was observed, irrespective of different blood pressure lowering strategies. Comprehensive risk factor control strategies are warranted to reduce cardiovascular disease risk in hypertensive patients.</p>","PeriodicalId":11869,"journal":{"name":"European Heart Journal - Quality of Care and Clinical Outcomes","volume":" ","pages":"669-676"},"PeriodicalIF":4.8,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141589990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness of intravascular ultrasound-guided percutaneous intervention in patients with acute coronary syndromes: a UK perspective.","authors":"Andrew S P Sharp, Tim Kinnaird, Nick Curzen, Ruba Ayyub, Jorge Emilio Alfonso, Mamas A Mamas, Henri Vanden Bavière","doi":"10.1093/ehjqcco/qcad073","DOIUrl":"10.1093/ehjqcco/qcad073","url":null,"abstract":"<p><strong>Background: </strong>Use of intravascular ultrasound (IVUS) during percutaneous coronary intervention (PCI) is associated with improved clinical outcomes over angiography alone. Despite this, the adoption of IVUS in clinical practice remains low.</p><p><strong>Aims: </strong>To examine the cost-effectiveness of IVUS-guided PCI compared to angiography alone in patients with acute coronary syndromes (ACS).</p><p><strong>Methods and results: </strong>A 1-year decision tree and lifetime Markov model were constructed to compare the cost-effectiveness of IVUS-guided PCI to angiography alone for two hypothetical adult populations consisting of 1000 individuals: ST-elevation myocardial infarction (STEMI) and unstable angina/non-ST-elevation myocardial infarction (UA/NSTEMI) patients undergoing drug-eluting stent (DES) implantation. The United Kingdom (UK) healthcare system perspective was applied using 2019/20 costs. All-cause death, myocardial infarction (MI), repeat PCI, lifetime costs, life expectancy, and quality-adjusted life-years (QALYs) were assessed. Over a lifetime horizon, IVUS-guided PCI was cost-effective compared to angiography alone in both populations, yielding an incremental cost-effectiveness ratio of £3649 and £5706 per-patient in STEMI and UA/NSTEMI patients, respectively.In the 1-year time horizon, the model suggested that IVUS was associated with reductions in mortality, MI, and repeat PCI by 51%, 33%, and 52% in STEMI and by 50%, 29%, and 57% in UA/NSTEMI patients, respectively. Sensitivity analyses demonstrated the robustness of the model with IVUS being 100% cost-effective at a willingness to pay threshold of £20 000 per QALY-gained.</p><p><strong>Conclusions: </strong>From a UK healthcare perspective, an IVUS-guided PCI strategy was highly cost-effective over angiography alone amongst ACS patients undergoing DES implantation due to the medium- and long-term reduction in repeat PCI, death, and MI.</p>","PeriodicalId":11869,"journal":{"name":"European Heart Journal - Quality of Care and Clinical Outcomes","volume":" ","pages":"677-688"},"PeriodicalIF":4.8,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138797994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive risk factor management for hypertensive patients.","authors":"Giacomo Frati, Giuseppe Biondi-Zoccai, Mariangela Peruzzi, Valentina Valenti","doi":"10.1093/ehjqcco/qcae078","DOIUrl":"10.1093/ehjqcco/qcae078","url":null,"abstract":"","PeriodicalId":11869,"journal":{"name":"European Heart Journal - Quality of Care and Clinical Outcomes","volume":" ","pages":"656-657"},"PeriodicalIF":4.8,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Key priorities for the implementation of the 2023 ESC Guidelines for the Management of Cardiomyopathies in low resource settings.","authors":"Ruxandra Jurcut, Roberto Barriales-Villa, Elena Biagini, Pablo Garcia-Pavia, Iacopo Olivotto, Alexandros Protonotarios, Eloisa Arbustini, Jens Mogensen, Perry Elliott, Elena Arbelo, Juan Pablo Kaski","doi":"10.1093/ehjqcco/qcae103","DOIUrl":"10.1093/ehjqcco/qcae103","url":null,"abstract":"<p><p>ESC Guidelines provide best practice, evidence-based recommendations for diagnosing and treating patients with cardiovascular diseases. It is not always possible for best practices to be followed, however, particularly in low-resource settings. To address this issue, a set of guideline-related documents were created to identify key priorities for users in these settings. The documents highlight the related recommendations and describe key strategies for clinicians to approach implementation of these recommendations or discuss alternatives which are in line with the intention of the recommendations, if not having all of the same advantages. The suggestions cannot be used as exact substitutes for the original recommendations in the guidelines, which have not been altered and continue to reflect best practice. This document on key priorities for low-resource settings was developed by the task force Chairs and other members of the task force which produced the 2023 ESC Guidelines for the management of cardiomyopathies, which are freely available on the ESC website (https://www.escardio.org/Guidelines). This document also underwent external review including international experts from within and beyond Europe and included non-ESC associations. The non-ESC associations were The Interamerican Society of Cardiology (IASC), The Pan-African Society of Cardiology (PASCAR), The Asian Pacific Society of Cardiology (APSC) and The Asean Federation of Cardiology (AFC).</p>","PeriodicalId":11869,"journal":{"name":"European Heart Journal - Quality of Care and Clinical Outcomes","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142805818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of the ARC-HBR Criteria in ST-Elevation Myocardial Infarction. Significance of Smoking as an Additional Bleeding Risk Factor.","authors":"Henri Kesti, Kalle Mattila, Samuli Jaakkola, Joonas Lehto, Nea Söderblom, Kalle Kalliovalkama, Pekka Porela","doi":"10.1093/ehjqcco/qcae104","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcae104","url":null,"abstract":"<p><strong>Background and aims: </strong>The Academic Research Consortium for High Bleeding Risk Criteria (ARC-HBR) are recommended by guidelines for bleeding risk assessment in ST-elevation myocardial infarction (STEMI). The aim of this study was to identify possible other risk factors and adjust the original ARC-HBR criteria for confounders.</p><p><strong>Methods: </strong>All consecutive STEMI patients managed in a Finnish tertiary hospital between 2016-2022 were identified using a database search. Data collection was done by reviewing electronic patient records. Bleeding risk was assessed according to the ARC-HBR criteria. The primary endpoint was non-access site bleeding academic research consortium (BARC) type 3 or 5 bleeding during 1-year follow-up.</p><p><strong>Results: </strong>A total of 1548 STEMI patients were analysed. HBR criteria was fulfilled in 661 (42.7%). Multivariable competing risk analysis identified only 4 individual ARC-HBR criteria as independent risk factors for bleeding. Smoking status was identified as a novel bleeding risk factor. Current and former smokers had increased bleeding risk compared with never smokers (hazard ratio [HR] 3.01, 95% confidence interval [CI] 1.62-5.61 and HR 1.99, CI 1.19-3.34). In those not meeting any ARC-HBR criteria, cumulative BARC 3 or 5 incidence of current smoking was 3.40% and intracranial haemorrhage (ICH) 1.36%. Thus, exceeding ARC-HBR definition for a major criterion. In the non-HBR group the prevalence of current smoking was 40.4% (n = 358).</p><p><strong>Conclusions: </strong>Current and former smoking predicts major bleeding complications after STEMI. Current smoking is highly prevalent among those classified as non-HBR according to the ARC-HBR criteria.</p>","PeriodicalId":11869,"journal":{"name":"European Heart Journal - Quality of Care and Clinical Outcomes","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between Hospital Mortality and Readmission Rates After Transcatheter Aortic Valve Replacement.","authors":"Dhaval Kolte, Archana Tale, Yang Song, Robert W Yeh","doi":"10.1093/ehjqcco/qcae102","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcae102","url":null,"abstract":"<p><strong>Background: </strong>There is substantial hospital-level variation in 30-day risk-standardized mortality rate (RSMR) and risk-standardized readmission rate (RSRR) after transcatheter aortic valve replacement (TAVR). However, the relationship between hospital RSMRs and RSRRs has not been well characterized.</p><p><strong>Methods: </strong>We analyzed data on 141,905 Medicare fee-for-service beneficiaries who underwent TAVR across 512 hospitals between October 1, 2015 and December 31, 2020. The primary and secondary outcomes of interest were 30-day all-cause mortality and 30-day all-cause readmissions, respectively. Hierarchical logistic regression models with random hospital-level intercepts were used to estimate RSMRs and RSRRs for each hospital. We used Pearson correlation coefficient (r) and restricted cubic spline regression to determine the relationship between RSMR and RSRR in the overall cohort and within subgroups based on hospital characteristics.</p><p><strong>Results: </strong>The median (IQR) hospital-level 30-day RSMR was 2.2% (2.1%-2.4%), ranging from 1.3% to 3.5%. Similarly, the median (IQR) hospital-level 30-day RSRR was 13.2% (12.7%-13.8%), ranging from 10.6% to 16.8%. In the overall cohort, there was weak correlation between 30-day RSMR and RSRR after TAVR (r=0.25, 95% CI 0.17-0.33, p<0.001). Subgroup analyses by hospital characteristics demonstrated weakest correlation between RSMR and RSRR for non-JCAHO accredited hospitals (r=0.07), hospitals in the Midwest (r=0.12) and West (r=0.14), and hospitals with low TAVR volume (r=0.15).</p><p><strong>Conclusions: </strong>Risk-standardized mortality and readmission rates after TAVR are weakly correlated, suggesting that hospital practices and processes of care influencing mortality are likely different from those influencing readmissions after TAVR, thereby necessitating measurement of both outcomes and developing specific interventions to decrease mortality and readmissions.</p>","PeriodicalId":11869,"journal":{"name":"European Heart Journal - Quality of Care and Clinical Outcomes","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supraventricular ectopic activity predicts postoperative atrial fibrillation, new onset atrial fibrillation and worse survival in obstructive hypertrophic cardiomyopathy.","authors":"Changrong Nie, Changsheng Zhu, Minghu Xiao, Zining Wu, Qiulan Yang, Zhengyang Lu, Tao Lu, Yanhai Meng, Shuiyun Wang","doi":"10.1093/ehjqcco/qcae101","DOIUrl":"https://doi.org/10.1093/ehjqcco/qcae101","url":null,"abstract":"<p><strong>Background: </strong>Supraventricular ectopic activity (SVEA) is a marker of foci that may initiate atrial fibrillation (AF) and is associated with worse survival. The types and frequencies of SVEA for predicting postoperative AF (POAF), new-onset AF, and clinical outcomes in obstructive hypertrophic cardiomyopathy(oHCM) remain unknown.</p><p><strong>Method: </strong>Our study consecutively recruited 961 patients with oHCM. All patients underwent a 24-hour Holter monitor before surgery.</p><p><strong>Results: </strong>POAF incidence was 20.7% and increased with the burden of premature atrial contractions (PACs). Multivariable analysis showed that supraventricular tachycardia (SVT) was independently associated with POAF, with the model including SVT yielding the largest area under the curve (AUC) [0.710, 95%CI 0.670-0.750] for predicting POAF. During a median follow-up of 2.9 years, 12 deaths, 60 new-onset AF, and 139 composite endpoints were observed. A Spearman correlation indicated a linear relationship between the incidence of new-onset AF and composite endpoints with PAC frequency. The Kaplan-Meier survival curves demonstrated that patients with PACs >200 beats/day had significantly higher cumulative rates of new-onset AF[HR 3.13, (95%CI 1.74-5.62), p<0.001] and composite endpoints [HR 2.00, (95%CI 1.30-3.06), p=0.002] than their counterparts. Adding PACs >200 beats/day to the multivariable model significantly improved net reclassification improvement (NRI) and integrated discrimination improvement (IDI) for predicting new-onset AF (NRI=0.264, IDI=0.033) and composite endpoints (NRI=0.233, IDI=0.014).</p><p><strong>Conclusion: </strong>The incidence of POAF was 20.7%, increasing with PACs severity. Furthermore, PACs burden was positively associated with a higher incidence of adverse events. Specially, PACs>200 beats/day may best predict a higher incidence of new-onset AF and worse survival.</p>","PeriodicalId":11869,"journal":{"name":"European Heart Journal - Quality of Care and Clinical Outcomes","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}