European Heart Journal: Acute Cardiovascular Care最新文献_第3页

From non-inferiority to superiority: the shift towards patient-centric outcomes. 从非劣效性到优势性：转向以患者为中心的结果。

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-03-22 DOI: 10.1093/ehjacc/zuaf004

Johan Verbeeck, Mickaël De Backer, Marc Buyse

引用次数: 0

European Society of Cardiology quality indicators for the management of acute coronary syndromes: developed in collaboration with the Association for Acute CardioVascular Care and the European Association of Percutaneous Cardiovascular Interventions of the ESC.

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-03-22 DOI: 10.1093/ehjacc/zuaf014

Xavier Rossello, Maribel Gonzalez-Del-Hoyo, Suleman Aktaa, Chris P Gale, Israel Barbash, Marc J Claeys, J J Coughlan, Joao Pedro Ferreira, Mary Galbraith, Margret Leosdottir, Francois Schiele, Sergio Raposeiras-Roubin, Maria Rubini Gimenez, Robert A Byrne, Borja Ibanez

{"title":"European Society of Cardiology quality indicators for the management of acute coronary syndromes: developed in collaboration with the Association for Acute CardioVascular Care and the European Association of Percutaneous Cardiovascular Interventions of the ESC.","authors":"Xavier Rossello, Maribel Gonzalez-Del-Hoyo, Suleman Aktaa, Chris P Gale, Israel Barbash, Marc J Claeys, J J Coughlan, Joao Pedro Ferreira, Mary Galbraith, Margret Leosdottir, Francois Schiele, Sergio Raposeiras-Roubin, Maria Rubini Gimenez, Robert A Byrne, Borja Ibanez","doi":"10.1093/ehjacc/zuaf014","DOIUrl":"10.1093/ehjacc/zuaf014","url":null,"abstract":"Aims: Closing the evidence-practice gap for the treatment of acute coronary syndrome (ACS) is central to improving quality of care. Under the European Society of Cardiology (ESC) framework, we aimed to develop updated quality indicators (QIs) for the evaluation of quality of care and outcomes for patients with ACS.Methods and results: A Working Group of experts including members of the ESC Clinical Practice Guidelines Task Force for ACS, Association for Acute Cardiovascular Care, and European Association of Percutaneous Cardiovascular Interventions followed the ESC methodology for QI development. This methodology involved (i) the identification of the domains of ACS care for the diagnosis and management of ACS; (ii) the construction of candidate QIs through a systematic review of the literature; and (iii) the selection of the final set of QIs (using a modified Delphi method). Five domains of care for the diagnosis and management of ACS were identified: (i) structural framework and logistics, (ii) in-hospital non-invasive care, (iii) invasive strategy and periprocedural management, (iv) secondary prevention interventions, and (v) outcomes. In total, 21 main QIs were selected, covering all five domains of care for the diagnosis and management of ACS.Conclusion: This document defines the five domains of ACS care and provides 21 QIs for the diagnosis and management of ACS. The updated ESC QIs for ACS may be used for quality improvement initiatives.","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":"145-154"},"PeriodicalIF":3.9,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Defining myocardial infarction: grades of severity or different aetiology.

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-03-22 DOI: 10.1093/ehjacc/zuaf025

Andrew P DeFilippis, Michael J Blaha

引用次数: 0

Answer: an uncommon electrocardiogram pattern in a case of acute chest pain.

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-03-22 DOI: 10.1093/ehjacc/zuaf020

Gulbadin Mufti, Shahid H Shali, A Shaheer Ahmed

引用次数: 0

Association between haemolysis markers and neuron-specific enolase in acute myocardial infarction complicated by cardiogenic shock patients supported with a microaxial flow pump. 微轴流泵支持下AMICS患者溶血标志物与神经元特异性烯醇化酶之间的关系

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-03-22 DOI: 10.1093/ehjacc/zuaf003

Zakaria Alaoui-Ismaili, Anika Klein, Jakob Josiassen, Ole Kristian Lerche Helgestad, Karoline Korsholm Jeppesen, Hanne Berg Ravn, Jesper Kjærgaard, Christian Hassager, Jacob Eifer Møller

{"title":"Association between haemolysis markers and neuron-specific enolase in acute myocardial infarction complicated by cardiogenic shock patients supported with a microaxial flow pump.","authors":"Zakaria Alaoui-Ismaili, Anika Klein, Jakob Josiassen, Ole Kristian Lerche Helgestad, Karoline Korsholm Jeppesen, Hanne Berg Ravn, Jesper Kjærgaard, Christian Hassager, Jacob Eifer Møller","doi":"10.1093/ehjacc/zuaf003","DOIUrl":"10.1093/ehjacc/zuaf003","url":null,"abstract":"Aims: Acute myocardial infarction complicated by cardiogenic shock (AMICS) is frequently preceded by out-of-hospital cardiac arrest (OHCA), with risk of anoxic brain injury. Neuron-specific enolase (NSE) is central to neuroprognostication; however, concomitant haemolysis can increase NSE independent of neuronal injury due to the presence of NSE in erythrocytes. This consideration is critical in AMICS patients treated with a microaxial flow pump (Impella, Abiomed, Danvers, MA, USA), where haemolysis is frequent.Methods and results: We identified consecutive AMICS patients receiving microaxial flow pump support ≥6 h from 2014 to 2022 in a tertiary Danish heart centre. Peak NSE and haemolysis biomarkers within 72 h following microaxial flow pump placement were used for analysis. Haemolysis was defined as plasma-free haemoglobin levels >31.5 µmol/L within 72 h from device placement. The population was stratified according to the presence or absence of haemolysis. The final study population comprised 44 patients with eligible NSE and haemolysis biomarkers. The median NSE was 85 µg/L. Patients with haemolysis had significantly higher NSE levels than those without (115 vs. 69 µg/L, P = 0.018). Neuron-specific enolase levels were similar between OHCA and non-OHCA patients. No significant difference in death from anoxic brain injury was observed between patients with NSE levels above and below 60 µg/L. Neuron-specific enolase revealed a significantly moderate correlation with all investigated haemolysis markers.Conclusion: Neuron-specific enolase was associated with haemolysis, and not anoxic brain injury, in AMICS patients supported with a microaxial flow pump.","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":"169-172"},"PeriodicalIF":3.9,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evidence-based medicine and the cardiac troponin 99th percentile for the diagnosis of acute myocardial infarction.

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-03-22 DOI: 10.1093/ehjacc/zuaf007

Peter E Hickman, Julia M Potter, Louise Cullen, Kai M Eggers, Martin Than, John W Pickering, William Parsonage, Jenny Doust

引用次数: 0

Cardiac Patients in ICU Research: An Urgent Call for Inclusion.

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-03-20 DOI: 10.1093/ehjacc/zuaf042

Steven M Hollenberg, Joseph E Parrillo

引用次数: 0

Outcomes of Mechanical Circulatory Support Devices Among Patients with Mechanical Complications of Acute Myocardial Infarction.

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-03-14 DOI: 10.1093/ehjacc/zuaf039

Ahmed M Younes, Ahmed K Mahmoud, Ibrahim Kamel, Linus Williams, Ahmed Maraey, Mahmoud Khalil, Ahmed Elzanaty, Rodrigo Bagur, Abdulla A Damluji, Jacqueline E Tamis-Holland, Islam Y Elgendy

{"title":"Outcomes of Mechanical Circulatory Support Devices Among Patients with Mechanical Complications of Acute Myocardial Infarction.","authors":"Ahmed M Younes, Ahmed K Mahmoud, Ibrahim Kamel, Linus Williams, Ahmed Maraey, Mahmoud Khalil, Ahmed Elzanaty, Rodrigo Bagur, Abdulla A Damluji, Jacqueline E Tamis-Holland, Islam Y Elgendy","doi":"10.1093/ehjacc/zuaf039","DOIUrl":"10.1093/ehjacc/zuaf039","url":null,"abstract":"Background: Mechanical complications of acute myocardial infarction (AMI) are rare but associated with considerably high mortality. While guidelines suggest mechanical circulatory support (MCS) devices as a potential bridge to definitive therapy, studies supporting this recommendation are limited.Methods: Using data from the National Inpatient Sample, a large admirative database in the United States, years 2016-2020, we identified AMI admissions (ST-elevation and non-ST-elevation myocardial infarction) with mechanical complications (ventricular septal defect, free wall rupture, or papillary muscle rupture). Logistic regression models adjusting for potential confounders were used to assess temporal trends in MCS utilization and to compare in-hospital mortality between those who received MCS versus none.Results: Among 4,450,219 AMI patients, 7,025 (0.2%) had a mechanical complication of which, 3,115 patients (44.3%) received at least one MCS device. There was a rising trend in MCS use (39.3% in 2016 to 48.9% in 2020, Ptrend=0.02), but there was no corresponding reduction in the incidence of in-hospital mortality (36.9% in 2016 vs 43.4% in 2020, Ptrend=0.75). There was no significant difference in in-hospital mortality between those who received MCS versus those who did not (48.4 vs 34.5% respectively.Conclusions: In this large observational analysis of AMI hospitalizations, mechanical complications were rare and associated with very high in-hospital mortality. Although the use of MCS has increased, however, in-hospital mortality rates remain high even among patients who received MCS. Further investigations are needed to clarify the role of MCS devices among patients with mechanical complications of AMI.","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Left ventricular-arterial coupling and mortality in the cardiac intensive care unit.

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-03-12 DOI: 10.1093/ehjacc/zuaf038

Luca Fazzini, Mitchell R Padkins, Kristoffer Berg-Hansen, Mauro Gori, Garvan C Kane, Dustin B Hillerson, Guido Tavazzi, Yogesh N V Reddy, Oh K Jae, Barry Borlaug, Jacob C Jentzer

{"title":"Left ventricular-arterial coupling and mortality in the cardiac intensive care unit.","authors":"Luca Fazzini, Mitchell R Padkins, Kristoffer Berg-Hansen, Mauro Gori, Garvan C Kane, Dustin B Hillerson, Guido Tavazzi, Yogesh N V Reddy, Oh K Jae, Barry Borlaug, Jacob C Jentzer","doi":"10.1093/ehjacc/zuaf038","DOIUrl":"https://doi.org/10.1093/ehjacc/zuaf038","url":null,"abstract":"Background: Left ventricular (LV) ventricular-arterial coupling (VAC) refers to the ratio of afterload (effective arterial elastance) to contractility (end-systolic elastance) as an integrated marker of cardiac performance. We sought to determine whether the echocardiographic VAC ratio, defined using the ratio of LV end-systolic volume (LVESV) to stroke volume (SV), predicted mortality in the cardiac intensive care unit (CICU).Methods: Mayo Clinic CICU patients from 2007 and 2018 were included. VAC ratio was calculated as the Teichholz LVESV divided by the SV calculated from LV outflow tract Doppler. The primary outcome was in-hospital mortality and the secondary outcome was all-cause one-year mortality.Results: A total of 4685 patients were included with a median age of 69 (58, 79) years (37.2% females), with acute coronary syndrome in 54.9% and heart failure in 49.0%. A higher VAC ratio was associated with greater severity of illness, worse echocardiographic findings, and more use of critical care therapies. A total of 329 (7%) patients died during hospitalization. Patients with a higher VAC ratio had higher in-hospital mortality overall and in each admission diagnosis subgroup. After multivariable adjustment, patients with a VAC ratio >2 were at higher risk of in-hospital mortality (adjusted OR 1.63, 95% CI 1.17-2.28, p=0.010). One-year mortality was higher for patients with a higher VAC ratio, especially VAC >2.Conclusion: Ventricular-arterial uncoupling was associated with worse outcomes in an unselected CICU cohort. The echocardiographic VAC ratio is a simple non-invasive bedside measure that can be used for risk prediction in the CICU.","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: Targeted proteomic profiling of cardiogenic shock in the cardiac intensive care unit.

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-03-05 DOI: 10.1093/ehjacc/zuaf033

引用次数: 0