European Heart Journal: Acute Cardiovascular Care最新文献

First Chapter of the 2025 ACVC Clinical Decision-Making Toolkit - Pulmonary Embolism. 2025年ACVC临床决策工具包第一章-肺栓塞。

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-05-27 DOI: 10.1093/ehjacc/zuaf076

Alessandro Galluzzo, Janine Pöss

引用次数: 0

Repolarization Abnormalities and Outcomes Among Patients with Cardiac Arrest. 心脏骤停患者的复极异常和结果。

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-05-27 DOI: 10.1093/ehjacc/zuaf077

Christopher Schenck, Soumya Banna, Noah Kim, Christine Nguyen, Emily J Gilmore, David M Greer, Rachel Beekman, P Elliott Miller

{"title":"Repolarization Abnormalities and Outcomes Among Patients with Cardiac Arrest.","authors":"Christopher Schenck, Soumya Banna, Noah Kim, Christine Nguyen, Emily J Gilmore, David M Greer, Rachel Beekman, P Elliott Miller","doi":"10.1093/ehjacc/zuaf077","DOIUrl":"https://doi.org/10.1093/ehjacc/zuaf077","url":null,"abstract":"Background: Changes in ventricular repolarization, observed as QTc prolongation, are frequently observed following cardiac arrest. The T-peak to T-end (TpTe) interval represents a period of increased susceptibility to ventricular arrhythmia. We posit that TpTe prolongation may be associated with adverse clinical outcomes in patients resuscitated from cardiac arrest.Methods: We included patients aged ≥18 years with both out-of-hospital and in-hospital cardiac arrest following return of spontaneous circulation (ROSC) who had an electrocardiogram (ECG) obtained within 24 hours following ROSC. The first ECG obtained was evaluated to determine the QTc and TpTe intervals. Hierarchical logistic regression was used to evaluate the association between prolongation of the QTc and TpTe intervals and clinical outcomes (in-hospital mortality and favorable neurologic outcome at hospital discharge).Results: We included 443 patients, with a median age of 61 years (IQR: 50-72 years), 60.5% male, 65.7% OHCA, and 29.8% with initial shockable rhythm. Overall, 310 patients had QTc prolongation (70.0%), and 284 had TpTe prolongation (64.1%). Patients with TpTe prolongation had a greater incidence of initial shockable rhythm (35.6% vs 19.5%, P<0.001) and higher initial lactate (8.6 vs 7.4 mmol/L, P=0.03). QTc prolongation was not associated with in-hospital mortality (odds ratio [OR]:1.27, 95% confidence interval [CI]: 0.75-2.14, P=0.37) or favorable neurologic outcome (OR:0.88, 95% CI: 0.50-1.54, P=0.65). TpTe prolongation was independently associated with in-hospital mortality (OR: 1.69, 95% CI: 1.01-2.85, P=0.05) but not favorable neurologic outcome (OR: 0.78, 95% CI: 0.45-1.37, P=0.39).Conclusions: TpTe interval prolongation, but not QTc interval prolongation, was associated with increased in-hospital mortality in patients resuscitated from cardiac arrest.","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Question: Silent stenosis to sudden shock: the unplanned culprit. 问题：无声狭窄到突然休克：意外的罪魁祸首。

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-05-27 DOI: 10.1093/ehjacc/zuaf029

Narendran Dhanasekaran, Bharath Raj Kidambi, Yeriswamy Mogalahally Channabasappa

引用次数: 0

Lactate Dynamics and Metabolic Differences in Cardiogenic Shock Across Clinical Contexts. 不同临床背景下心源性休克的乳酸动力学和代谢差异。

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-05-19 DOI: 10.1093/ehjacc/zuaf074

Johannes Grand

引用次数: 0

Underrepresentation and exclusion of patients with cardiovascular disease in intensive care randomized controlled trials. 重症监护随机对照试验中心血管疾病患者的代表性不足和排除。

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-05-16 DOI: 10.1093/ehjacc/zuaf023

Tariq N Ali, Alyssa A Grimshaw, Alexander Thomas, Michael A Solomon, Joseph S Ross, P Elliott Miller

{"title":"Underrepresentation and exclusion of patients with cardiovascular disease in intensive care randomized controlled trials.","authors":"Tariq N Ali, Alyssa A Grimshaw, Alexander Thomas, Michael A Solomon, Joseph S Ross, P Elliott Miller","doi":"10.1093/ehjacc/zuaf023","DOIUrl":"10.1093/ehjacc/zuaf023","url":null,"abstract":"Aims: The complexity of the contemporary cardiac intensive care unit has increased due to a growing prevalence of multisystem, non-cardiac illnesses. Despite this increase, patients with cardiovascular disease (CVD) are often under-represented in intensive care randomized controlled trials (RCT). We sought to quantify the representation of patients with CVD comorbidities in intensive care RCTs.Methods and results: We searched MEDLINE for trials published from 2007 to 2019 with the five highest journal impact factors in the disciplines of critical care medicine, general internal medicine, and cardiovascular disease. Prospective RCTs in the adult (age ≥18 years), intensive care setting with ≥50 individuals were included. Study characteristics, proportion of patients with CVD and cardiovascular exclusion criteria were extracted independently by two reviewers. We used multivariable logistic regression analysis to identify independent predictors of cardiovascular exclusion and representation. A total of 412 eligible RCTs were identified for analysis, 132 (32.0%) of which included specific CVD-related exclusion criteria with a history of heart failure (29.5%) and of ischaemic heart disease (26.5%) being the most common exclusions. Exclusions were more likely in multicentre trials and varied substantially across study intervention categories. Representation of CVD, reflected by the reporting of any CVD history, was noted in 150 (36.4%) RCTs. Of those reporting, the prevalence of any CVD, ischaemic heart disease and heart failure were 15.7%, 13.2%, and 10.2%, respectively.Conclusion: Those with comorbid CVD are both frequently excluded and underrepresented in intensive care RCTs, limiting the application of RCTs to this physiologically complex patient population.","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":"259-267"},"PeriodicalIF":3.9,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12082296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiac patients in intensive care unit research: an urgent call for inclusion. ICU研究中的心脏病患者：迫切需要纳入。

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-05-16 DOI: 10.1093/ehjacc/zuaf042

Steven M Hollenberg, Joseph E Parrillo

引用次数: 0

Answer: Triphasic radial pulse in a patient with abdominal pain. 答：腹痛患者的三相桡动脉脉搏。

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-05-16 DOI: 10.1093/ehjacc/zuae129

Jonathan Chun-Hei Cheung, Geoffrey Chi Chun Tang, Albert Kam Ming Chan

引用次数: 0

Outcomes with mechanical circulatory support devices among patients with mechanical complications of acute myocardial infarction. 机械循环支持装置在急性心肌梗死机械并发症患者中的应用效果。

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-05-16 DOI: 10.1093/ehjacc/zuaf039

Ahmed M Younes, Ahmed K Mahmoud, Ibrahim Kamel, Linus Williams, Ahmed Maraey, Mahmoud Khalil, Ahmed Elzanaty, Rodrigo Bagur, Abdulla A Damluji, Jacqueline E Tamis-Holland, Islam Y Elgendy

{"title":"Outcomes with mechanical circulatory support devices among patients with mechanical complications of acute myocardial infarction.","authors":"Ahmed M Younes, Ahmed K Mahmoud, Ibrahim Kamel, Linus Williams, Ahmed Maraey, Mahmoud Khalil, Ahmed Elzanaty, Rodrigo Bagur, Abdulla A Damluji, Jacqueline E Tamis-Holland, Islam Y Elgendy","doi":"10.1093/ehjacc/zuaf039","DOIUrl":"10.1093/ehjacc/zuaf039","url":null,"abstract":"Aims: The aim of this study is to examine the trends and outcomes of mechanical circulatory support (MCS) device use among patients with mechanical complications of acute myocardial infarction (AMI).Methods and results: Using data from the National Inpatient Sample (a large admirative database in the USA) years 2016-20, we identified AMI admissions (ST-elevation and non-ST-elevation myocardial infarction) with mechanical complications (ventricular septal defect, free wall rupture, or papillary muscle rupture). Among 4 450 219 AMI patients, 7025 (0.2%) had a mechanical complication of which 3115 patients (44.3%) received at least one MCS device. There was a rising trend in MCS use (39.3% in 2016 to 48.9% in 2020, Ptrend = 0.02), but there was no corresponding reduction in the incidence of in-hospital mortality (36.9% in 2016 vs. 43.4% in 2020, Ptrend = 0.75). There was no significant difference in in-hospital mortality between those who received MCS vs. those who did not (48.4 vs. 34.5%, respectively).Conclusion: In this large observational analysis of AMI hospitalizations, mechanical complications were rare and associated with very high in-hospital mortality. Although the use of MCS has increased, in-hospital mortality rates remain high even among patients who received MCS. Further investigations are needed to clarify the role of MCS devices among patients with mechanical complications of AMI.","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":"288-294"},"PeriodicalIF":3.9,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breaking barriers, bridging gaps, and redefining acute cardiovascular care: May issue highlights. 打破障碍，弥合差距，重新定义急性心血管护理：可能的问题亮点。

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-05-16 DOI: 10.1093/ehjacc/zuaf062

Pascal Vranckx, David A Morrow, Sean van Diepen, Frederik H Verbrugge

引用次数: 0

Impressions and voices from the Acute CardioVascular Care congress 2025. 2025年ACVC大会的印象和声音。

IF 3.9 2区医学

European Heart Journal: Acute Cardiovascular Care Pub Date : 2025-05-16 DOI: 10.1093/ehjacc/zuaf047

Michelle Roßberg, Milica Aleksic, Janine Pöss, Alessandro Galluzzo

引用次数: 0