Mathieu Kerneis, Enrico Ammirati, Clément Delmas, Ward Heggermont, Stephane Heymans, Max Lenz, Rosalinda Madonna, Marco Morosin, Hannah Schaubroeck, Alessandro Sionis, Gal Tsaban, Jamol Uzokov, Katarine Vardanyan, Christophe Vandenbriele, François Roubille
{"title":"Clinical Management of Acute myocarditis in daily practice: an expert practical view.","authors":"Mathieu Kerneis, Enrico Ammirati, Clément Delmas, Ward Heggermont, Stephane Heymans, Max Lenz, Rosalinda Madonna, Marco Morosin, Hannah Schaubroeck, Alessandro Sionis, Gal Tsaban, Jamol Uzokov, Katarine Vardanyan, Christophe Vandenbriele, François Roubille","doi":"10.1093/ehjacc/zuaf057","DOIUrl":"https://doi.org/10.1093/ehjacc/zuaf057","url":null,"abstract":"<p><strong>Background: </strong>Acute Myocarditis (AM) encompasses a broad spectrum of clinical presentations and causes. Despite the recent advances in cardiovascular imaging, pathology, virology and genetics, specific therapies are still lacking.</p><p><strong>Purpose: </strong>This collaborative review aims to analyze the current evidence to answer practical questions that physicians may face during the early management of patients presenting with an acute form of the disease, complicated or not.This review analyzes current evidence to address practical questions posed by acute cardiovascular physicians during the early management of acute, often fulminant, myocarditis.</p><p><strong>Methods and results: </strong>Based on the current literature, this review provides a step-by-step approach to treat AM patients from their admission in the cardiac intensive care unit (CICU) to discharge, by answering 10 clinical questions: Might this patient be suffering from an AM? Should I hospitalize this patient and, if so, where? Which cardiac imaging exam should I perform and what can I learn from it? Is this patient requiring an EMB? What should the non-invasive etiological work-up be? Is his episode of AM of viral, toxic, or other origin? Does this patient need specific treatments or mechanical circulatory support? Is there an indication for guideline-directed medical heart failure treatment? When can the patient be discharged and resume physical activity? Notably, this review highlights the need to build a multidisciplinary response team to address the many diagnostic and therapeutic challenges of AM patients. It also points out the lack of evidence to guide treatment of these patients.</p>","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In perspective: Development and External Validation of a Deep Learning Electrocardiogram Model For Risk Stratification of Coronary Revascularization Need in the Emergency Department.","authors":"Konstantin A Krychtiuk, Alessandro Sionis","doi":"10.1093/ehjacc/zuaf058","DOIUrl":"https://doi.org/10.1093/ehjacc/zuaf058","url":null,"abstract":"","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intra-aortic balloon pump in patients with heart failure-related cardiogenic shock: The Altshock-2 trial In Perspective.","authors":"Uwe Zeymer, David A Morrow","doi":"10.1093/ehjacc/zuaf056","DOIUrl":"https://doi.org/10.1093/ehjacc/zuaf056","url":null,"abstract":"","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abraham M Cherukara, Lawrence Rudski, Michelle Grinman, David M Levine
{"title":"Bringing Heart Care Home: Management of Acute Cardiovascular Pathologies in the Home Hospital.","authors":"Abraham M Cherukara, Lawrence Rudski, Michelle Grinman, David M Levine","doi":"10.1093/ehjacc/zuaf053","DOIUrl":"https://doi.org/10.1093/ehjacc/zuaf053","url":null,"abstract":"<p><p>The Home Hospital (HH) model delivers hospital-level acute care in patients' homes, offering a scalable, patient-centered alternative to traditional brick-and-mortar (BAM) facilities. By integrating multidisciplinary teams, remote monitoring, and tailored interventions, HH reduces hospital length of stay, enhances patient satisfaction, and lowers healthcare costs. Despite these benefits, universally established diagnosis-specific management guidelines remain limited, leading to variability in care delivery. Current practices rely on clinical experience and governing protocols, but structured HH pathways must be developed based on system-dependent resources and infrastructure. Standardizing care in HH will allow to ensure patient safety, optimize clinical outcomes, and expand access to acute care beyond conventional hospital settings. This article outlines a blueprint for acute cardiac care in HH, focusing on heart failure, atrial arrhythmias, and venous thromboembolism while emphasizing the critical role of patient selection, recruitment strategies, management protocols, and escalation criteria.</p>","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra Braillon, Thibault Leclercq, Alain Lalande, Kevin Guillen, Charles Guenancia
{"title":"Answer: Have the remnographic eye: a rare cause of pericardial effusion after myocardial infarction.","authors":"Alexandra Braillon, Thibault Leclercq, Alain Lalande, Kevin Guillen, Charles Guenancia","doi":"10.1093/ehjacc/zuae130","DOIUrl":"https://doi.org/10.1093/ehjacc/zuae130","url":null,"abstract":"","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor related to \"An uncommon electrocardiogram pattern in a case of acute chest pain\" by Gulbadin Mufti, Shahid H. Shali, and A. Shaheer Ahmed.","authors":"Gheorghe-Andrei Dan","doi":"10.1093/ehjacc/zuaf050","DOIUrl":"https://doi.org/10.1093/ehjacc/zuaf050","url":null,"abstract":"","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kamila Kurkiewicz-Sawczak, Filip Sawczak, Filip Baszkowski, Kinga Walska-Świerc, Malwina Baturo, Weronika Pelczar-Płachta, Dominika Wysocka, Marta Kałużna-Oleksy, Waldemar Bobkowski
{"title":"Acute Heart Failure with Systolic Dysfunction in Paediatric Patients: Aetiology, Risk Factors, and In-hospital Prognosis.","authors":"Kamila Kurkiewicz-Sawczak, Filip Sawczak, Filip Baszkowski, Kinga Walska-Świerc, Malwina Baturo, Weronika Pelczar-Płachta, Dominika Wysocka, Marta Kałużna-Oleksy, Waldemar Bobkowski","doi":"10.1093/ehjacc/zuaf049","DOIUrl":"https://doi.org/10.1093/ehjacc/zuaf049","url":null,"abstract":"<p><strong>Background: </strong>Paediatric acute heart failure (AHF) differs from adult cases, and less numerous population limits research aimed at improving clinical practice and prognosis.</p><p><strong>Aims: </strong>We aimed to evaluate outcomes and prognostic factors in the paediatric population of AHF patients with left ventricular ejection fraction (EF) <50%, or systemic right ventricular fractional area change <40%.</p><p><strong>Methods: </strong>This single-centre retrospective cohort study included 162 consecutive paediatric patients hospitalised for new-onset AHF with systolic dysfunction or the first exacerbation with reported systolic dysfunction of chronic heart failure (CHF). Patients were categorized into two subgroups: those with >5% improvement in EF on follow-up echocardiography before discharge (n=115) and those with either EF deterioration, ≤5% EF improvement, or death during hospitalisation (n=47).</p><p><strong>Results: </strong>The study contained 58% males and 42% females. The median age was 1 (IQR 0-8) year, 14 (IQR 2-101) months. The mortality rate was 12.3%. AHF aetiologies included congenital heart defects (51.2%), cardiomyopathy (20.4%), infections (14.2%), arrhythmias (11.7%), and others (2.5%). Our study demonstrated independent factors of worse outcomes: cardiomyopathies aetiology [OR 2.762 (1.210-6.307)], older age [OR 1.006 (1.000-1.011)], and factors of better prognosis: infective aetiology [OR 0.083 (0.010-0.664)], higher EF [OR 0.953 (0.905-0.999)], SpO2 [OR 0.951 (0.905-0.992)]. In contrast to CHF exacerbation, de novo AHF had better outcomes (p=0.014).</p><p><strong>Conclusions: </strong>AHF with systolic dysfunction in children has an unfavourable prognosis, however most patients improved during hospitalisation. In our study, cardiomyopathy aetiology predicted worse outcomes. In turn, infective aetiology, younger age, higher EF, and SpO2 were independent factors of better prognosis.</p>","PeriodicalId":11861,"journal":{"name":"European Heart Journal: Acute Cardiovascular Care","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}