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Prevalensi Skabies pada Warga Binaan di Lembaga Pemasyarakatan Kelas IIA Tuminting Manado 万鸦老 Tuminting IIA 级惩教所囚犯的疥疮患病率
Medical Scope Journal Pub Date : 2024-02-25 DOI: 10.35790/msj.v6i2.53598
Raul C. Zachawerus, Nurdjannah J. Niode, Marlyn G. Kapantow
{"title":"Prevalensi Skabies pada Warga Binaan di Lembaga Pemasyarakatan Kelas IIA Tuminting Manado","authors":"Raul C. Zachawerus, Nurdjannah J. Niode, Marlyn G. Kapantow","doi":"10.35790/msj.v6i2.53598","DOIUrl":"https://doi.org/10.35790/msj.v6i2.53598","url":null,"abstract":"Abstract: Scabies is a contagious skin disease caused by the mite Sarcoptes scabiei var, hominis. The prevalence of scabies in Indonesia in 2016 is estimated at 4.6-12.9% of the 261.6 million population. Scabies ranks 3rd out of the 12 most common skin infections. This study aimed to determine the prevalence of scabies among inmates in Lembaga Pemasyarakatan kelas IIA Tuminting Manado (correctional insitution). This was a quantitative and descriptive study with a cross sectional design using The DeSkab (Deteksi Skabies) questionnaire. The results showed that 86 inmates out of a total of 190 inmates were detected of having scabies (45.3%) dominated by age 25-44 years (51.2%), middle education (76.7%), and unqualified occupancy density (100%). The most common distributions of lesions were between fingers (30.7%), followed by front part of wrist (20.2%), and elbow (13.5%). Cardinal signs of scabies were itching worse at night (98.8%), followed by lesions (86.1%), and itching complained by roommates (70.9%). In conclusion, the prevalence of scabies in Lembaga Pemasyarakatan kelas IIA Tuminting Manado is 45.3%. Inmates with detected scabies are dominated by age 25-44 years, middle education, unqualified occupancy density, distribution of lesion between fingers, and cardinal sign as itching worse at night.\u0000Keywords: scabies; correctional institution; inmates\u0000 \u0000 Abstrak: Skabies merupakan penyakit kulit menular yang diakibatkan oleh tungau Sarcoptes scabiei var, hominis. Skabies menempati peringkat 3 dari 12 penyakit infeksi kulit tersering. Penelitian ini bertujuan untuk mengetahui prevalensi skabies pada warga binaan di Lembaga Pemasyarakatan kelas IIA Tuminting Manado. Jenis penelitian ialah deskriptif kuantitatif dengan desain potong lintang dan menggunakan kuesioner DeSkab (Deteksi Skabies). Hasil penelitian mendapatkan 86 warga binaan dari total 190 warga binaan yang terdeteksi skabies (45,3%), didominasi oleh usia 25-44 tahun (51,2%), tingkat pendidikan menengah (76,7%), dan kepadatan hunian yang tidak memenuhi syarat (100%). Sebaran lokasi lesi yang terbanyak ialah sela jari tangan (30,7%), diikuti pergelangan tangan depan (20,2%), dan siku luar (13,5%). Tanda kardinal skabies yang tersering muncul ialah keluhan gatal pada malam hari (98,8%), diikuti adanya bintil/lecet/borok (86,1%), dan keluhan gatal pada orang lain (sekamar) (70,9%). Simpulan penelitian ini ialah prevalensi skabies pada warga binaan Lembaga Pemasyarakatan Kelas IIA Tuminting Manado sebesar 45,3%. Warga binaan terdeteksi skabies didominasi oleh usia 25-44 tahun, tingkat pendidikan menengah, kepadatan hunian yang tidak memenuhi syarat, sebaran lokasi lesi di sela jari tangan, dan tanda kardinal skabies keluhan gatal pada malam hari.\u0000Kata kunci: skabies; lembaga pemasyarakatan; warga binaan","PeriodicalId":118600,"journal":{"name":"Medical Scope Journal","volume":"8 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140432205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validity of Predictive Markers for Post ERCP Pancreatitis Patients: A Single Centre Study ERCP术后胰腺炎患者预测指标的有效性:单中心研究
Medical Scope Journal Pub Date : 2024-01-28 DOI: 10.35790/msj.v6i2.51513
M. Tendean, Toar D. B. Mambu, Leonard A. Melatunan
{"title":"Validity of Predictive Markers for Post ERCP Pancreatitis Patients: A Single Centre Study","authors":"M. Tendean, Toar D. B. Mambu, Leonard A. Melatunan","doi":"10.35790/msj.v6i2.51513","DOIUrl":"https://doi.org/10.35790/msj.v6i2.51513","url":null,"abstract":"Abstract: Endoscopic retrograde cholangiopancreatography (ERCP) is a proprietary procedure, endoscopic modality, and specialized procedure used to diagnose and treat disorders of the pancreatic and biliary systems. The incidence of reported post-ERCP complications varied among several studies including post ERCP pancreatitis (PEP), duodenal perforation, and cholangitis. In this study, the author would like to show certain intra procedural factors related to PEP incidence. This was a retrospective study of secondary data of patients undergoing ERCP procedures from 2017-2022 at Prof. Dr. R. D. Kandou Hospital, Manado. Length of procedure, cannulation on pancreatic duct, pancreatogram, double wire technique, and the use of certain common bile duct (CBD) stone retrieval techniques such as endoscopic papillary balloon dilatation (EPBD) were recorded and analyzed. The results showed that based on the analyzed data, the percentage of pancreas cannulation was 8%, pancreatogram 5%, double-wire technique 3%, and EPBD procedure 10%, Incidence rate of PEP in all ERCP procedures was 19%. Increased amylase/lipase enzymes were found in 13 of 24 patients (54%) who underwent cannulation; 8 of 16 patients (50%) who underwent pancreatogram; 4 of 9 patients (44%) who underwent double wire procedure; and 10 of 30 patients (33%) who underwent EPBD. This PEP could be caused by several risk factors during ERCP including cannulation, pancreatogram, double wire, and EPBD. Number of cannulation attempt could result in trauma to the ampulla. Pancreatogram could result in hydrostatic, chemical, and allergic injury. Any manipulation of the pancreas that caused trauma could trigger the incidence of PEP. Assessment of the occurrence of PEP was based on increases in lipase and amylase enzyme values by four times the normal value and tested 6 hours after procedure. We could reduce the incidence of PEP by providing prophylactic therapy before ERCP. In conclusion, PEP is the most common complication in ERCP procedures and can be risky in patients with high risk factors. In this study, factors that affecting the incidence of PEP are cannulation, pancreatogram, double wire and EPBD.\u0000Keywords: endoscopic retrograde cholangiopancreatography; pancreatitis; complications","PeriodicalId":118600,"journal":{"name":"Medical Scope Journal","volume":"3 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139592113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation between Doctor-Patient Communication with Patient Satisfaction and Loyalty 医患沟通与患者满意度和忠诚度之间的相关性
Medical Scope Journal Pub Date : 2024-01-28 DOI: 10.35790/msj.v6i2.53161
Nancy Lampus, Dewi S. S. Wuisan
{"title":"Correlation between Doctor-Patient Communication with Patient Satisfaction and Loyalty","authors":"Nancy Lampus, Dewi S. S. Wuisan","doi":"10.35790/msj.v6i2.53161","DOIUrl":"https://doi.org/10.35790/msj.v6i2.53161","url":null,"abstract":"Abstract: Effective communication between doctors and patients has been recognized as a key factor in influencing the patient’s experience during treatment and will affect patient loyalty. This study aimed to investigate and analyze the correlation between doctor and patient communication with patient satisfaction and loyalty, in the context of health services. This was a cross-sectional study using a questionnaire as an instrument to collect data from several patients receiving outpatient treatment at the cardiovascular unit at XYZ Hospital. Data were analyzed multivariate using the PLS-SEM statistical method with SmartPLS®4 software. The results were obtained from 182 respondents who met the inclusion criteria taken in 2023 by purposive sampling with a questionnaire from individuals who had received cardiovascular outpatient services at XYZ Hospital. The five aspects of doctor communication skills were proven to have significant and positive effects. The strongest influence was shown in the empathy factor of communication by a doctor (R2 = 0.274; p-value 0.011; CI 0.086 – 0.479). This study proved the positive impact of patient satisfaction on patient loyalty at XYZ Hospital. From the findings of this study, managerial implications could be drawn for the development of doctors’ communication skills with patients, maintaining doctor quality, and strengthening the hospital image by providing the best services for patients. In conclusion, effective communication plays an important role in increasing patient satisfaction and loyalty toward health services in hospitals. It is necessary to maintain and improve skills in doctor-patient communication.\u0000Keywords: effective communication; patient satisfaction; patient loyalty","PeriodicalId":118600,"journal":{"name":"Medical Scope Journal","volume":"395 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140490786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hubungan Jenis dan Siklus Kemoterapi dengan Derajat Neuropati pada Pasien Keganasan 化疗类型和周期与恶性肿瘤患者神经病变程度的关系
Medical Scope Journal Pub Date : 2024-01-28 DOI: 10.35790/msj.v6i2.53140
Harlinda Haroen, Indriaty Gimon
{"title":"Hubungan Jenis dan Siklus Kemoterapi dengan Derajat Neuropati pada Pasien Keganasan","authors":"Harlinda Haroen, Indriaty Gimon","doi":"10.35790/msj.v6i2.53140","DOIUrl":"https://doi.org/10.35790/msj.v6i2.53140","url":null,"abstract":"Abstract: Antineoplastic chemotherapy agents in cancer treatment can cause peripheral neuropathy. Antineoplastic agents associated with chemotherapy-induced peripheral neuropathy include platinum-based drugs (carboplatin, cisplatin and oxaliplatin) and taxane (paclitaxel and docetaxel). This study aimed to evaluate the relationship between the type and cycle of chemotherapy with the level of neuropathy in malignant patients at Prof. Dr. R. D. Kandou Hospital, Manado, in 2022. The results obtained 43 cancer patients aged 18-65 who underwent chemotherapy, especially drugs from the platinum group (81.4%) such as oxaliplatin (62.8%). The majority of cases were colorectal adenocarcinoma (63%). Using the Toronto Score, the majority of subjects experienced mild neuropathy (55.8%), followed by without neuropathy (32.5%) and moderate neuropathy (11.6%). Although there was an indication of a relationship between the type of chemotherapy and the severity of neuropathy, the results were not statistically significant (p=0.069). In conclusion, there is no relationship between the type and cycle of chemotherapy with the level of neuropathy in cancer patients.\u0000Keywords: neuropathy; chemotherapy cycles; types of chemotherapy\u0000 \u0000Abstrak: Agen kemoterapi antineoplastik dalam pengobatan kanker dapat menyebabkan neuropati perifer. Agen antineoplastik terkait neuropati perifer yang diinduksi kemoterapi termasuk obat berbasis platinum (carboplatin, cisplatin dan oxaliplatin) dan taxane (paclitaxel dan docetaxel). Penelitian ini bertujuan untuk mengetahui hubungan jenis dan siklus kemoterapi dengan keparahan neuropati pada pasien keganasan di RSUP Prof. Dr. R. D. Kandou Manado pada tahun 2022. Hasil penelitian mendapatkan 43 pasien kanker berusia 18-65 tahun yang telah menjalani kemoterapi, khususnya obat berbasis platinum (81,4%) seperti oxaliplatin (62,8%). Jenis keganasan yang terbanyak ialah adenokarsinoma kolorektal (63%). Dengan menggunakan Skor Toronto, didapatkan mayoritas subjek mengalami neuropati ringan (55,9%) diikuti tanpa neuropati (32,5%) dan neuropati sedang (11,6%). Meski ada indikasi hubungan antara jenis kemoterapi dengan tingkat neuropati, hasilnya tidak bermakna secara statistik (p=0,069). Simpulan penelitian ini ialah tidak terdapat hubungan antara jenis dan siklus kemoterapi dengan tingkat neuropati pada pasien keganasan.\u0000Kata kunci: neuropati; siklus kemoterapi; jenis kemoterapi","PeriodicalId":118600,"journal":{"name":"Medical Scope Journal","volume":"5 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139592197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The importance of preoperative evaluation to predict the outcome of percutaneous nephrostomy 术前评估对预测经皮肾造瘘术结果的重要性
Medical Scope Journal Pub Date : 2024-01-28 DOI: 10.35790/msj.v6i2.52858
Ronald J. Datu, Eko Arianto, Ari Astram, Christof Toreh
{"title":"The importance of preoperative evaluation to predict the outcome of percutaneous nephrostomy","authors":"Ronald J. Datu, Eko Arianto, Ari Astram, Christof Toreh","doi":"10.35790/msj.v6i2.52858","DOIUrl":"https://doi.org/10.35790/msj.v6i2.52858","url":null,"abstract":"Abstract: Percutaneous nephrostomy (PCN) is an invasive procedure equal to a grade 4 penetrating kidney trauma. It should be carefully considered whether has a greater benefit or risk. There are currently no parameters or scores to predict the outcome of nephrostomy in our center. This study aimed to conduct a review to find out whether there were parameters or scores that could be used to predict the outcome of nephrostomy. This research used relevant studies obtained from Clinical Key, PubMed, Semantic Scholar, Dimensions, and Science Direct published in the last 10 years and written in English. Studies on children and transplant cases were excluded. Studies that met the PICO criteria were selected. The results showed that of the 141 articles collected, and filtered with inclusion criteria, exclusion criteria, and PICO criteria, finally the remaining were three studies selected. The studies discussed about classification, SFU grading system, and complication of nephrostomy; significant variables affecting recoverability of renal function; patients’ characteristics and outcomes of double J ureteral stenting (DJS) and PCN; and 12-month-post-operative creatinine level change. Most patients who failed DJS had increased creatinine level. However, one of the indications for a nephrostomy was stenting failure. In conclusion, predictor factors that can affect the renal recovery after nephrostomy include kidney shape and size, pre-nephrostomy creatinine levels, urine output, state of infection, and degree of hydronephrosis. However, the evidence is still not enough. Further research is needed on the predictor factors for renal recovery after nephrostomy.\u0000Keywords:  percutaneous nephrostomy; hydronephrosis; kidney function; predictors","PeriodicalId":118600,"journal":{"name":"Medical Scope Journal","volume":"4 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139592292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Persepsi Masyarakat Kota Manado Terhadap Vaksin Booster Covid-19 sebagai Syarat Berwisata 万鸦老市居民对把接种 Covid-19 加强型疫苗作为旅行条件的看法
Medical Scope Journal Pub Date : 2023-12-13 DOI: 10.35790/msj.v6i1.45458
Kevin A. G. Mandak, D. H. Pangemanan, D. V. Doda
{"title":"Persepsi Masyarakat Kota Manado Terhadap Vaksin Booster Covid-19 sebagai Syarat Berwisata","authors":"Kevin A. G. Mandak, D. H. Pangemanan, D. V. Doda","doi":"10.35790/msj.v6i1.45458","DOIUrl":"https://doi.org/10.35790/msj.v6i1.45458","url":null,"abstract":"Abstract: Coronavirus disease 2019 (Covid 19) is an infectious disease that is currently a global pandemic. This situation greatly impacts the tourism sector in Indonesia. Vaccination is expected to be one of the preventive measures used to control the transmission of Covid-19. This study aimed to determine the perception of the people in Manado City towards the Covid-19 booster vaccine as a prerequisite for traveling. This was a qualitative study using interview method. The interview was conducted using in-depth interview technique and guidelines. The results obtained 15 people of Kelurahan Paniki Bawah, Kecamatan Mapanget, Kota Manado as respondents. Most respondents had positive perception towards the Covid-19 booster vaccine as a prerequisite of traveling. Most respondents had good general understanding of the benefits of the Covid-19 vaccine and they agreed with the Covid-19 booster vaccine as a prerequisite of traveling. In conclusion, most people in Manado City have a good and positive perception of the Covid-19 booster vaccine as a prerequisite of traveling.\u0000Keywords: Covid-19; booster vaccine; travelling prerequisite\u0000 \u0000Abstrak: Penyakit infeksi coronavirus 2019 (Covid 19) telah menjadi pandemi global. Situasi tersebut sangat berdampak pada sektor pariwisata di Indonesia. Pemberian vaksin diharapkan dapat menjadi salah satu pencegahan yang digunakan untuk mengendalikan penularan Covid-19. Penelitian ini bertujuan untuk mengetahui persepsi masyarakat Kota Manado terhadap vaksin booster Covid-19 sebagai syarat berwisata. Penelitian ini merupakan penelitian kualitatif dengan metode wawancara secara terstruktur dan menggunakan pedoman wawancara. Hasil penelitian mendapatkan 15 masyarakat Kelurahan Paniki Bawah, Kecamatan Mapanget, Kota Manado sebagai responden penelitian. Persepsi responden terhadap vaksin booster Covid-19 sebagai syarat berwisata menunjukkan bahwa sebagian besar memiliki persepsi positif terhadap vaksin booster Covid-19 sebagai syarat berwisata. Responden memiliki pemahaman umum yang baik mengenai manfaat vaksin covid dan mereka setuju dengan himbauan vaksin bo booster oster Covid-19 sebagai syarat berwisata. Simpulan penelitian ini ialah masyarakat Kota Manado umumnya memiliki persepsi yang baik terhadap vaksin booster Covid-19 sebagai syarat berwisata.\u0000Kata kunci: Covid-19; vaksin booster; syarat berwisata","PeriodicalId":118600,"journal":{"name":"Medical Scope Journal","volume":"27 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139004753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pola Penggunaan Obat Antihipertensi pada Pasien Rawat Jalan di Rumah Sakit X Manado 万鸦老 X 医院门诊患者使用抗高血压药物的模式
Medical Scope Journal Pub Date : 2023-12-13 DOI: 10.35790/msj.v6i1.51701
Widya A. Lolo, Gayatri Citraningtyas, Imam Jayanto
{"title":"Pola Penggunaan Obat Antihipertensi pada Pasien Rawat Jalan di Rumah Sakit X Manado","authors":"Widya A. Lolo, Gayatri Citraningtyas, Imam Jayanto","doi":"10.35790/msj.v6i1.51701","DOIUrl":"https://doi.org/10.35790/msj.v6i1.51701","url":null,"abstract":"Abstract: Hypertension is a degenerative disease with a high prevalence which is still a health problem worldwide. This study aimed to determine the pattern of the use of antihypertensive drugs in outpatients at X hospital in Manado. This was a descriptive and observational study with a cross sectional design. Data collection was carried out retrospectively by tracing patients’ medical record data in 2022. The results obtained 56 patients that met the criteria. The patients’ characteristic data showed that hypertension was dominant in women (59%), aged 56-65 years (27%), and included in controlled hypertension (55.4%). Data on drugs received by patients showed that out of 56 patients, there were 19 patients (34%) using a single antihypertensive and 37 patients (66%) using a combination of antihypertensives.  Amlodipine was the most widely used as single antihypertensive, namely 13 patients (68.5%), while the most widely used combination of antihypertensives was amlodipine and candesartan as many as 16 patients (43%). In conclusion, the most widely used single antihypertensive is amlodipine and the combination therapy is amlodipine and candesartan.\u0000Keywords: pattern of drug use; antihypertensives; single drug; combination therapy\u0000  \u0000Abstrak: Hipertensi merupakan salah satu penyakit degeneratif dengan prevalensi tinggi yang hingga kini masih menjadi masalah kesehatan di dunia. Penelitian ini bertujuan untuk mengetahui pola penggunaan obat antihipertensi pada pasien rawat jalan di rumah sakit X Manado. Metode penelitian yang digunakan ialah observasional deskriptif dengan rancangan potong lintang.  Pengumpulan data dilakukan secara retrospektif dengan menelusuri data rekam medis pasien tahun 2022. Hasil penelitian mendapatkan 56 pasien yang memenuhi kriteria penelitian. Pada data karakteristik pasien diketahui bahwa penyakit hipertensi dominan terjadi pada perempuan (59%), usia 56-65 tahun (27%), dan termasuk dalam hipertensi terkontrol (55,4%). Data obat yang diterima pasien menunjukkan bahwa dari 56 pasien, terdapat 19 pasien (34%) menggunakan antihipertensi tunggal dan 37 pasien (66%) menggunakan antihipertensi kombinasi. Amlodipin merupakan antihipertensi tunggal yang paling banyak digunakan yaitu sebanyak 13 dari 19 pasien (68,5%), sedangkan terapi antihipertensi kombinasi yang paling banyak digunakan yaitu amlodipin dan kandesartan sebanyak 16 dari 37 pasien (43%). Simpulan penelitian ini ialah obat antihipertensi tunggal yang paling banyak digunakan ialah amlodipin dan terapi kombinasi ialah  amlodipin dan kandesartan.\u0000Kata kunci: pola penggunaan obat; antihipertensi; obat tunggal; terapi kombinasi","PeriodicalId":118600,"journal":{"name":"Medical Scope Journal","volume":"222 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139005774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Acetazolamide Additional Therapy on Loop Diuretic for Achieving an Effective Treatment in Acute Heart Failure Patients: A Systematic Review 乙酰唑胺对环形利尿剂的辅助治疗对急性心力衰竭患者获得有效治疗的影响:系统回顾
Medical Scope Journal Pub Date : 2023-12-10 DOI: 10.35790/msj.v6i1.52794
A. T. Fadilla, Muhammad Sabri, Idham Junantaruna, Ajibaskoro P. Ibrahim
{"title":"Effect of Acetazolamide Additional Therapy on Loop Diuretic for Achieving an Effective Treatment in Acute Heart Failure Patients: A Systematic Review","authors":"A. T. Fadilla, Muhammad Sabri, Idham Junantaruna, Ajibaskoro P. Ibrahim","doi":"10.35790/msj.v6i1.52794","DOIUrl":"https://doi.org/10.35790/msj.v6i1.52794","url":null,"abstract":"Abstract: Hospital readmissions are primarily caused by signs and symptoms of congestion of acute heart failure (AHF). Loop diuretics are commonly used to treat volume excess. It has been suggested by earlier studies in AHF patients that combination of loop diuretics with acetazolamide can increase the effectiveness of loop diuretics. This study aimed to obtain the impact of acetazolamide addition on loop diuretic therapy in AHF patients and assess the benefit of the combination. This was a systematic review using PubMed and ScienceDirect to retrieve data in 2013 and 2023, focusing on Randomized Controlled Trials (RCTs) involving AHF patients treated with both loop diuretics and acetazolamide. The results showed that 573 patients from a total of four RCTs were included in the study. Acetazolamide additional therapy helped loop diuretic to increase natriuresis (in all of the studies) and urine output (in two studies). The congestion symptoms also reduced in patients who received acetazolamide additional therapy on dose 500 mg intravenously within three days (p<0.05) in two studies. However, patients who received acetazolamide therapy also had an increase in serum creatinine levels in two studies. In conclusion, adding acetazolamide to loop diuretic therapy can increase the effectiveness of loop diuretics to achieve successful decongestion in AHF patients. Additionally, acetazolamide-treated individuals exhibit natriuresis and urin output higher than those in the control group, despite it also raises serum creatinin level.\u0000Keywords: acetazolamide; loop diuretics; acute heart failure; decongestion","PeriodicalId":118600,"journal":{"name":"Medical Scope Journal","volume":"2 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138584870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sindrom Wellens Tipe B dengan Penyumbatan pada Satu Pembuluh Darah Koroner: Laporan Kasus 韦伦斯综合征 B 型伴有一根冠状动脉血管阻塞:病例报告
Medical Scope Journal Pub Date : 2023-12-10 DOI: 10.35790/msj.v6i1.52494
Edmond L. Jim
{"title":"Sindrom Wellens Tipe B dengan Penyumbatan pada Satu Pembuluh Darah Koroner: Laporan Kasus","authors":"Edmond L. Jim","doi":"10.35790/msj.v6i1.52494","DOIUrl":"https://doi.org/10.35790/msj.v6i1.52494","url":null,"abstract":"Abstract: Wellens syndrome describes a pattern of electrocardiographic (ECG) changes, especially typical T waves, that threaten the patient's safety if further examination and management are delayed. We reported a 52-year-old male with a history of previous heart attacks. The patient had a history of hypertension, hypercholestrolemia, and active smoker. Vital signs indicated stable hemodynamics. On ECG examination, a deep inversion T wave was obtained in the V2-V6 leads. In echocardio-graphy, normal heart chamber dimensions, concentric LVH, with grade I diastolic dysfunction, LV EF 52% (SIMPSONS BP), apical to mid-anterior hypokinetics, other normokinetic segments, MR Mild, with normal RV contractility. Patient was carried out elective percutaneous coronary intervention (PCI) with the results of one kulprit lesion found in LAD, 50-60% proximal-mid stenosis, 80% distal tubular stenosis, discrete stenosis 50-60% D2, and Promus Premiere 2.5x20 mm stent installation in the distal LAD. The result of TIMI flow 3 angiography evaluation was no dissection or residual stenosis that concluded CAD 1VD post DCA-PCI with 1 Stent in LAD. After the PCI, complaint of chest pain was absent, vital sign examination and physical examinations were within normal limits. The therapy provided consisted of 0.9% NaCl infusion 500cc/24 hours intravenously for hydration after PCI, and dual antiplatelets After day-3 treatment there was no increase in urea and creatinine; therefore, outpatient treatment was carried out followed by phase 2 cardiac rehabilitation.\u0000Keywords: Wellens’ syndrome; typical T wave; stenosis; left anterior descending artery\u0000  \u0000Abstrak: Sindrom Wellens menggambarkan pola perubahan elektrokardiografi (EKG), terutama gelombang T tipikal yang mengancam keselamatan pasien bila terlambat dilakukan pemeriksaan dan penatalaksanaan lebih lanjut. Kami melaporkan seorang laki-laki beruria 52 tahun dengan riwayat serangan jantung sebelumnya. Pasien memiliki riwayat hipertensi, riwayat hiperkolestrolemia, dan perokok aktif. Tanda vital menunjukkan hemodinamik stabil. Pada pemeriksaan EKG  didapatkan gelombang T inversi dalam pada sadapan V2-V6. Pada ekokardiografi didapatkan dimensi ruang jantung normal, LVH konsentrik, dengan disfungsi diastolik grade I, LV EF 52% (SIMPSONS BP), hipokinetik apikal hingga mid anterior, segmen lain normokinetik, MR Mild , dengan kontraktilitas RV normal. Pasien dilakukan intervensi koroner perkutan elektif dengan hasil satu lesi kulprit terdapat pada LAD, stenosis 50-60% proksimal-mid, stenosis tubular 80% distal, stenosis diskret 50-60% D2, dan dilakukan pemasangan stent Promus Premiere 2,5x20mm di distal LAD. Hasil evaluasi angiografi TIMI flow 3, tidak terdapat diseksi, ataupun stenosis residual yang menyimpulkan CAD 1VD post DCA-PCI dengan 1 Stent di LAD. Pasca tindakan, keluhan nyeri dada tidak ada, pemeriksaan tanda vital dan pemeriksaan fisik dalam batas normal. Terapi yang diberikan terdiri dari infus NaCl 0,9% 500cc/24jam in","PeriodicalId":118600,"journal":{"name":"Medical Scope Journal","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138584903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hubungan Tingkat Kepatuhan Minum Obat dengan Kadar Gula Darah dan Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di Klinik Imanuel Manado 万鸦老伊曼纽尔诊所 2 型糖尿病患者坚持服药与血糖水平和生活质量之间的关系
Medical Scope Journal Pub Date : 2023-12-06 DOI: 10.35790/msj.v6i1.51696
D. Mpila, W. Wiyono, W. A. Lolo
{"title":"Hubungan Tingkat Kepatuhan Minum Obat dengan Kadar Gula Darah dan Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di Klinik Imanuel Manado","authors":"D. Mpila, W. Wiyono, W. A. Lolo","doi":"10.35790/msj.v6i1.51696","DOIUrl":"https://doi.org/10.35790/msj.v6i1.51696","url":null,"abstract":"Abstract: Effectiveness of therapy in patients with type 2 diabetes mellitus (T2DM) is strongly supported by medication adherence. This study aimed to determine the correlation between the level of medication adherence with blood glucose level and the quality of life (QoL) of patients with T2DM at the Imanuel Clinic Manado. This was an observational analytical study with a cross sectional design. Data were obtained prospectively in the period of August to September 2023 with a sample size of 45 respondents. Data of patient medication adherence were obtained using MARS-5 questionnaire; data of patient quality of life using the DQoL-BCI questionnaire; and data of blood glucose level (FPG/2-h PG) were obtained from patient medical records. The correlation between medication adherence and blood glucose levels was statistically analyzed using the chi-square test, while the correlation between medication adherence and patients’ QoL was analyzed using Spearman Rho. A p-value of <0.05 was considered statistically significant. The results showed that there were significant correlations between medication adherence and patients’ blood glucose level (p=0.017), as well as between medication adherence and patient QoL (p=0.05) with a positive correlation coefficient and moderate correlation level (r=0.294). In conclusion, medication adherence plays an important role in the management of type 2 diabetes mellitus patients to achieve blood glucose target and improved quality of life.\u0000Keywords: type 2 diabetes mellitus; medication adherence; blood glucose level; quality of life\u0000  \u0000Abstrak: Efektivitas terapi pada pasien diabetes melitus tipe 2 (DMT2) sangat didukung oleh kepatuhan minum obat. Penelitian ini bertujuan untuk mengetahui hubungan tingkat kepatuhan minum obat dengan kadar gula darah dan kualitas hidup pasien DMT2 di Klinik Imanuel Manado. Penelitian bersifat analitik observasional dengan desain potong lintang. Data diperoleh secara prospektif pada periode Agustus–September 2023 dengan jumlah sampel sebanyak 45 responden. Data kepatuhan minum obat diperoleh menggunakan kuesioner MARS-5; data kualitas hidup pasien menggunakan kuesioner DQoL-BCI; dan data kadar gula darah (GDP, GD2PP) diperoleh dari rekam medik pasien. Hubungan antara kepatuhan minum obat dan kadar gula darah dianalisis secara statistik menggunakan uji chi-square, sedangkan hubungan kepatuhan minum obat dan kualitas hidup pasien dianalisis menggunakan Spearman Rho. Nilai p<0,05 dianggap bermakna secara statistik. Hasil penelitian menunjukkan terdapat hubungan bermakna antara kepatuhan minum obat dengan kadar gula darah (p=0,017), serta antara kepatuhan minum obat dan kualitas hidup pasien (p=0,05), dengan koefisien korelasi arah positif dan tingkat korelasi cukup kuat (r=0,294). Simpulan penelitian ini ialah kepatuhan minum obat berperan penting dalam tatalaksana terapi pasien diabetes melitus tipe 2 untuk mencapai target kadar gula darah dan perbaikan kualitas hidup.\u0000Kata kunci: diabetes","PeriodicalId":118600,"journal":{"name":"Medical Scope Journal","volume":"36 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138596574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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