European Journal of Clinical and Experimental Medicine最新文献

{"title":"Hygienic assessment of the occurrence and development of emotional burnout syndrome among medical students and its prevention","authors":"Valentyna Chorna, Hanna Syrota, Mariia Syrota, Svitlana Khliestova, Vlada Poliarush, Lyudmyla Hudzevych","doi":"10.15584/ejcem.2023.3.4","DOIUrl":"https://doi.org/10.15584/ejcem.2023.3.4","url":null,"abstract":"Introduction and aim. Emotional burnout syndrome has become increasingly common in recent decades, regardless of the field of professional activity. The purpose of our study was to compare the prevalence of emotional burnout in medical students of Vinnytsia National Medical University before the beginning of the academic semester and during the passing of exams. Material and methods. An anonymous, voluntary survey before the start of study was taken by 300 students, among them 82.3% were women, 17.7% were men. Results. During the exams, 362 students took part, including 76.2% women and 24.1% men. According to the results of the study, the proportion of the “average” degree of exhaustion increased in second-year students by 15.6%; third-year students by 44.4%. The “high” degree of emotional exhaustion according to the results of the study before the start of training was found in male students of the third year – 44.4% and 36.4% of male students of the sixth year. During the exams, the rate of “high” emotional exhaustion was observed in first-year students, increasing from 12.5% to 18% and in sixth-year students from 36.4% to 50%. Conclusion. Thus, it was found that female students are the most adapted to the educational load, to passing exams, which affects the psychosomatic state of future doctors.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135588031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of novel iron regulators in the treatment of diabetic nephropathy","authors":"Dekai Banerjee, Ginpreet Kaur, Bappaditya Chatterjee, Hemant Joshi, Seema Ramniwas, Hardeep Singh Tuli","doi":"10.15584/ejcem.2023.3.28","DOIUrl":"https://doi.org/10.15584/ejcem.2023.3.28","url":null,"abstract":"Introduction and aim. The novel advancements of upcoming iron regulators used to treat diabetic nephropathy have implicated a common manifestation of combination chelation therapy used to eliminate end-stage renal disease associated with inflammation and iron imbalance that is altered by renal iron absorption. However, iron accumulation in the clustered kidneys that filter blood may cause problems that affect diabetic blood sugar regulation. Material and methods. A well-designed method was employed to discover relevant research publications on iron chelators and their potential to treat diabetic nephropathy. “Iron chelators”, “diabetic nephropathy”, “end-stage renal disease”, and “chelation therapy” were searched in Google Scholar, Web of Science, PubMed, and EMBASE. Analysis of literature. Although the specific etiology and development have not been fully explored, emerging evidence on iron pathophysiology helps comprehend the pathogenesis of acute kidney damage and chronic kidney disease, which crucially provides novel iron chelation therapy techniques. Ferroptosis and hepcidin marker proteins increase oxidative/nitrifying stress and kidney injury. Iron chelator medicines including deferoxamine, deferasirox, and deferiprone were tested as prophylactic strategies. Conclusion. This article covers both preclinical and clinical aspects of iron chelators to avoid diabetic nephropathy, including novel iron therapies that must be reviewed when selecting dosing regimens.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135588035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors affecting work-life balance and psychological resilience levels of nurses working in internal clinics during COVID-19","authors":"Tuba Korkmaz Aslan, Rukiye Burucu, Yunus Akdoğan","doi":"10.15584/ejcem.2023.3.12","DOIUrl":"https://doi.org/10.15584/ejcem.2023.3.12","url":null,"abstract":"Introduction and aim. COVID-19 intensity has affected both the psychology of the nurses and the balance established between their work and social lives. In this study, it was aimed to examine the work-life balance and psychological resilience levels of nurses. Material and methods. Four Hundred and seventy two nurses, working in various hospitals and internal units in Turkey, voluntarily participated in the study. Data was collected online using the Work-Life Balance Scale, Brief Psychological Resilience Scale, and the Personal Information Form. Results. The sub-dimensions of the work-life balance scale include allocation of time for yourself (β=1.892; p<0.001), life merely being based on work (β=-0.513; p<0.05) and work-life balance; affect the psychological resilience score (β=-0.364; p<0.05). Based on this, devoting time for yourself has a positive effect on psychological resilience, while others have a negative effect. The total score of the nurses on work-life balance is 51.51±7.22 and their psychological resilience score is 15.27±3.93. Conclusion. Psychological resilience is affected by educational status, marital status, having children, and working schedule; work-life balance is affected by educational status, marital status, having children, income levels, and working schedule; while work-life balance sub-dimensions are affected by education, marital status, having children, income levels, place of work and working schedule. Both work-life balance and its sub-dimensions affect the psychological resilience of nurses.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135589028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer patients’ attitudes towards holistic complementary and alternative medicine in the management of sleep problems","authors":"Dilek Baykal, Burcu Dedeoğlu Demir, Dilek Yildirim","doi":"10.15584/ejcem.2023.3.21","DOIUrl":"https://doi.org/10.15584/ejcem.2023.3.21","url":null,"abstract":"Introduction and aim. Sleep problems are frequently experienced in cancer patients and complementary and alternative medicine (CAM) is solve the problem. However, patients’ attitudes towards this practice are crucial. This study was purpose to investigate the attitudes of cancer patients towards CAM practices in the management of sleep problems. Material and methods. This cross-sectional. and descriptive study was conducted between February-June 2020, on 140 cancer patients in oncology/haematology clinics, three different hospitals in Istanbul. Data were collected by using the Information Form, “Richard Campbell Sleep Questionnaire and The Attitudes towards Holistic Complementary and Alternative Medicine scale”. Results. It was found that the patients had problems with sleep in general 42.74±21.31, mostly in the aspect of the quality of sleep 36.28±26.1. It was determined that stage IV cancer, education and income level of patients affect sleep problems. While female holistic health attitudes were more negative and, their attitudes towards CAM were positive. It was found in the analysis of variance that was performed to determine the difference between the mean scores towards sleep problems of patients in different stages (F=3.062; p<0.05). Conclusion. It was found that cancer patients usually had sleep problems, and their attitudes towards CAM practices were positive.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135587883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of sulfide anion in the development of chronic alcoholic hepatitis under the conditions of modulation of adenosine monophosphate kinase – a correlational study","authors":"Andrii Mykytenko, Oleh Akimov, Oleksandr Shevchenko, Karine Neporada","doi":"10.15584/ejcem.2023.3.24","DOIUrl":"https://doi.org/10.15584/ejcem.2023.3.24","url":null,"abstract":"Introduction and aim. Hydrogen sulfide (H 2 S) has attracted the attention of researchers as a novel signaling molecule that affects vascular metabolism, immune function, stress and inflammation. It plays an important role in pathophysiological disorders under the conditions of the development of obesity, diabetes, non-alcoholic fatty liver disease and cardiovascular diseases. The purpose of this work is to establish correlation ratios of H 2 S concentration with markers of oxidative-nitrosative stress and extracellular matrix metabolism of the liver during chronic alcoholic hepatitis modeling and AMPK modulation by phenformin and doxorubicin. Material and methods. The experiments were performed on 36 white, sexually mature male Wistar rats, weighing 180-220 g. Alcoholic hepatitis was modelled by alcohol administration, on the background of alcoholic hepatitis animals received phenformin orally at a dose of 10 mg/kg or doxorubicin at a dose of 1.25 mg/kg intraperitoneally. Statistical processing of the results of biochemical studies was carried out using the non-parametric method of Spearman to determine correlations. Results. H 2 S during alcoholic hepatitis inversely proportionally strongly correlates with the concentration of nitrites, oxyproline and arginase activity. Phenformin administration during alcoholic hepatitis leads to formation of inversely proportionally strongly correlation of H 2 S with the production of superoxide anion radical, the concentration of malondialdehyde, activities of constitutive NO-synthases, nitrite reductases, nitrate reductases, and arginase. Doxorubicin administration during alcoholic hepatitis leads to formation of directly proportional strongly correlation of H 2 S with the activity of constitutive NO-synthases, nitrite reductases, nitrate reductases. Conclusion. Administration of phenformin or doxorubicin expands correlations between H 2 S and indicators of oxidative-nitrosative stress.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135589025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the relationship between job satisfaction and professional behaviors in pediatric nurses","authors":"Fatma Dinç, Dilek Yıldız","doi":"10.15584/ejcem.2023.3.22","DOIUrl":"https://doi.org/10.15584/ejcem.2023.3.22","url":null,"abstract":"Introduction and aim. Pediatric nurses play an important role in ensuring quality healthcare through job satisfaction and professional behaviors. This study aims to examine the relationship between job satisfaction and professional behaviors in pediatric nurses. Material and methods. This was a descriptive and cross-sectional study.The sample of the study consisted of 244 pediatric nurses who worked in tertiary university hospitals in Turkey and agreed to participate in the study. Data were obtained through face-to-face interviews using a personal information form, the job satisfaction scale for nurses (JSSN), and the behavioral inventory form for professionalism in nursing (BIPN). Data were analyzed using the SPSS 22.0 software and evaluated using descriptive statistics, independent t-tests, one-way ANOVA, Pearson correlation, and simple linear regression analysis. Results. The nurses’ JSSN and BIPN means scores were 3.42±0.59 and 5.69±4.05, respectively. A statistically significant moderate positive relationship was found between the pediatric nurses’ professional behaviors and job satisfaction (R=0.342; p<0.001). The regression analysis revealed that professional behaviors significantly and positively influenced job satisfaction in pediatric nurses (β=0.050; p<0.001). Conclusion. This study found that pediatric nurses had a moderate level of job satisfaction and a low level of professional behaviors, and as their professional behavior increased, their job satisfaction also increased.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135588036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of dysarthria in a 55-year-old female patient with multiple sclerosis by means of an IT tool based on respiratory and phonatory examination – a case study","authors":"Wojciech A. Warmbier, Małgorzata Popiel, Agnieszka Guzik, Mariusz Drużbicki, Halina Bartosik-Psujek","doi":"10.15584/ejcem.2023.3.29","DOIUrl":"https://doi.org/10.15584/ejcem.2023.3.29","url":null,"abstract":"Introduction and aim. There are no available objective tools for assessing dysarthric disorders in the course of multiple sclerosis (MS). The aim of the study is to analyse a case of mixed dysarthria in a 55-year-old female patient in the course of secondary progressive MS and to present the severity of the patient’s dysarthric disorder in contrast with the control group as evaluated by means of an IT tool based on respiratory and phonatory examination. Description of the case. A 55-year-old patient was admitted to the Clinic of Neurology with the Stroke Unit due to a worsening condition in the course of MS. She was examined with an objective tool for respiratory and phonatory disorders. Her results were, then, compared to those of 24 healthy individuals from the control group, matched in terms of sex and age. Following speech parameters were analysed: phonetics of utterances, number of produced syllables per breath during the execution of individual texts, sound quality, intonation, and the total performance time of each. Conclusion. The analysed case indicates that the developed objective IT tool is a promising diagnostic method that can facilitate diagnosis and can be used in clinical practice.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135587880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morbidity profile and outcome of new-born admitted in sick newborn care units of Uttar Pradesh, India","authors":"Satya Prakash Singh, Harish Chandra Paliwal, Saket Shekhar, Poonam Kushwaha","doi":"10.15584/ejcem.2023.3.27","DOIUrl":"https://doi.org/10.15584/ejcem.2023.3.27","url":null,"abstract":"Introduction and aim. Reduction in child morbidity and mortality is result of upgradation of infrastructure and quality of public health care services. India alone accounts for 30% of the global neonatal deaths occur in India that occurs due to preventable cause. So, the aim of this study was to assess the pattern and status of neonatalmortality observed in SNCUs of Uttar Pradesh, India. Material and methods. Descriptive study was conducted based on secondary data obtained from sick new born care units (SNCU) online database from 89 Government-supported SNCUs of Uttar Pradesh, from April 2014 to March 2016. Data obtained included age, weight, sex, diagnosis, and outcome. Results. 22933 neonates admitted in SNCU were included in study with 14269 (62.2%) were males and 8664 (37.8%) females. Majority of the subject (20070; 87%) were in 0-5 days old age group. Most (72.5%) of admitted new-born improved and discharged. Low birth weight was significantly (χ 2 = 1334.2, p<0.001) related with outcome. Birth asphyxia contributed to maximum (36.11%) number of deaths, followed by respiratory distress syndrome (25.21%), sepsis (15.38%), prematurity and extremely low birth weight (5.8%). Conclusion. Improved antenatal care, improved access to health facility, timely referral of high-risk cases, capacity building, intensive interventional management can reduce neonatal mortality and its complications. Study also warrants, in-depth community-based qualitative study to identify gender-specific, equity issues.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135587882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of nonpharmacological nursing practices related to thirst and the thirst of patients in the intensive care unit","authors":"Sevim Çelik, Münevver Şengül, Elif Karahan","doi":"10.15584/ejcem.2023.3.3","DOIUrl":"https://doi.org/10.15584/ejcem.2023.3.3","url":null,"abstract":"Introduction and aim. Thirst is a significant symptom and stressor among patients in the intensive care unit. The aim of this study is to assess the severity of thirst and associated symptoms experienced by patients in the intensive care unit, and to evaluate the nursing practices related to addressing thirst. Material and methods. This descriptive and correlational study involved a total of 66 patients in the intensive care unit. Severity of thirst experienced by these patients was assessed using a numeric rating scale. The nursing practices related to assessing thirst severity on admission to the unit, on the third day, and on the seventh day were also recorded. Results. Our findings showed a statistically significant increase in the levels of thirst, dry mouth, bad taste and odor in the mouth, as well as sensitivity and dryness in the throat among patients on the seventh day of hospitalization (p<0.05).Among nursing interventions, communication with the patient was the most frequently applied intervention during the seven-day period, with a range of 98.5% to 100%. biochemical control (100%), ventilation of the unit (100%), and temperature regulation (100%) were also frequently applied. Conclusion. The patients had all the symptoms of thirst.The frequency of nursing interventions increased in parallel with the severity of thirst.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135588032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unilateral double maxillary paramolars in a non-syndromic child – a rare case report","authors":"Sonu Acharya, Bismay Singh, Alkananda Sahoo, Brinda Suhas Godhi","doi":"10.15584/ejcem.2023.3.7","DOIUrl":"https://doi.org/10.15584/ejcem.2023.3.7","url":null,"abstract":"Introduction and aim. Extra teeth are the teeth which are more than the normal number of teeth in jaws. They can be present on a single side or both sides, singular or many, maxillary or mandibular. Paramolars are uncommon supernumerary molars which can be present on buccal or palatal side of molars. Very few reports of supernumerary teeth in maxilla or mandible being paramolars has been stated. No literature on unilateral twin paramolars in maxilla has been reported in literature yet. This is a first case report of unilateral twin paramolars in maxilla in a child. Description of the case. This case report describes the presence of unilateral double maxillary paramolars and their handling in a thirteen-year-old boy, whose primary concern was that of severe pain in maxilla on both sides. After an identification of double maxillary paramolars was put forward and established by cone beam computer tomography, both the paramolars were extracted. Conclusion. Supernumerary teeth have to be removed as soon as detected otherwise they can lead to malocclusion and pain due to caries after pulp involvement.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135589023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}