Emergency Radiology最新文献

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Unusual causes of Small bowel obstruction: a review of the literature and revisited cross-sectional imaging checklist. 小肠梗阻的不寻常原因:文献综述和重新审视的横断面成像检查表。
IF 1.7
Emergency Radiology Pub Date : 2024-10-01 Epub Date: 2024-06-27 DOI: 10.1007/s10140-024-02256-8
Nilkanth L Pal, Swamini D Panandiker, Glory Katiyar, Jeevan A Vernekar
{"title":"Unusual causes of Small bowel obstruction: a review of the literature and revisited cross-sectional imaging checklist.","authors":"Nilkanth L Pal, Swamini D Panandiker, Glory Katiyar, Jeevan A Vernekar","doi":"10.1007/s10140-024-02256-8","DOIUrl":"10.1007/s10140-024-02256-8","url":null,"abstract":"<p><p>Intestinal obstruction is a common surgical emergency with high morbidity and mortality. Patients presenting with features of small bowel obstruction need urgent evaluation to avoid complications such as bowel gangrene, perforation, or peritonitis. Imaging is necessary in most cases of suspected bowel obstruction, to take an appropriate decision, for apt patient management. Among the common causes of small bowel obstruction, adhesions, external herniae, malignancies, and Crohn's disease top the chart. Imaging helps in determining the presence of obstruction, the severity of obstruction, transition point, cause of obstruction, and associated complications such as strangulation, bowel gangrene, and peritonitis. This review is based on the cases with unusual causes of bowel obstruction encountered during our routine practice and also on the extensive literature search through the standard textbooks and electronic databases. Through this review we want our readers to have sound knowledge of the imaging characteristics of the uncommon yet important causes of bowel obstruction. We have also revisited and structured a checklist to simplify the approach while reporting a suspected case of small bowel obstruction. Imaging plays a key role in the diagnosis of small bowel obstruction and in determining the cause and associated complications. Apart from the common causes of small bowel obstruction, we should also be aware of the uncommon causes of small bowel obstruction and their imaging characteristics to make an accurate diagnosis and for apt patient management.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141455979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges in diagnosis of calcaneal fractures: an examination using the WIDI SIM platform. 诊断小关节骨折的挑战:使用 WIDI SIM 平台进行的检查。
IF 1.7
Emergency Radiology Pub Date : 2024-10-01 Epub Date: 2024-07-06 DOI: 10.1007/s10140-024-02267-5
Dahyun Kang, Abheek Raviprasad, Kevin Pierre, Jay Talati, Thomas Kent, Bayar Batmunh, Linda Lanier, Roberta M Slater, Christopher L Sistrom, Anthony A Mancuso, Ivan Davis, Dhanashree A Rajderkar
{"title":"Challenges in diagnosis of calcaneal fractures: an examination using the WIDI SIM platform.","authors":"Dahyun Kang, Abheek Raviprasad, Kevin Pierre, Jay Talati, Thomas Kent, Bayar Batmunh, Linda Lanier, Roberta M Slater, Christopher L Sistrom, Anthony A Mancuso, Ivan Davis, Dhanashree A Rajderkar","doi":"10.1007/s10140-024-02267-5","DOIUrl":"10.1007/s10140-024-02267-5","url":null,"abstract":"<p><strong>Introduction: </strong>The calcaneus is the most commonly fractured tarsal bone. Diagnosis is often challenging due to subtle radiographic changes and requires timely identification to prevent complications, including subtalar arthritis, neurovascular injury, malunion, osteomyelitis, and compartment syndrome. Treatment varies based on fracture type, with non-surgical methods for non-displaced stress fractures and surgical interventions for displaced or intra-articular fractures.</p><p><strong>Methods: </strong>This study utilized the Wisdom in Diagnostic Imaging Simulation (WIDI SIM) platform, an emergency imaging simulation designed to assess radiology resident preparedness for independent call. During an 8-hour simulation, residents were tested on 65 cases across various imaging modalities of varying complexity, including normal studies. A single, unique case of calcaneal fracture was included within the simulation in four separate years of testing. Cases were assessed using a standardized grading rubric by subspecialty radiology faculty, with errors subsequently classified by type.</p><p><strong>Results: </strong>A total of 1279 residents were tested in five separate years on the findings of calcaneal fractures of 5 different patients. Analysis revealed a consistent pattern of missed diagnoses across all training years, primarily attributed to observational errors. There was limited improvement with training progression as all training years exhibited similar average performance levels.</p><p><strong>Conclusions: </strong>Calcaneal fractures pose a diagnostic challenge due to their frequent subtle radiographic findings, especially in stress fractures. Simulation-based evaluations using WIDI SIM highlighted challenges in radiology residents' proficiency in diagnosing calcaneal fractures. Addressing these challenges through targeted education and exposure to diverse cases is essential to improve diagnostic accuracy and reduce complications with calcaneal fractures.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141537781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging of acute scrotal infections, complications and mimics. 急性阴囊感染、并发症和模拟病例的影像学检查。
IF 1.7
Emergency Radiology Pub Date : 2024-10-01 Epub Date: 2024-07-11 DOI: 10.1007/s10140-024-02263-9
Anjali Agrawal, Monika Sharma, Smitha Sriram, Ana Blanco, Refky Nicola, Arjun Kalyanpur
{"title":"Imaging of acute scrotal infections, complications and mimics.","authors":"Anjali Agrawal, Monika Sharma, Smitha Sriram, Ana Blanco, Refky Nicola, Arjun Kalyanpur","doi":"10.1007/s10140-024-02263-9","DOIUrl":"10.1007/s10140-024-02263-9","url":null,"abstract":"<p><p>Infection of the scrotum and its contents is the most common cause of acute scrotum. Imaging plays an important role in evaluating disease extent, severity and its complications. Sonography is the modality of choice for imaging the acute scrotum. This pictorial review discusses the varied clinical and imaging features of scrotal infections and their complications, with correlative CT, when available.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does the site, size, and number of necrotic collections affect the outcome of necrotizing pancreatitis? - a prospective analysis. 坏死组织的部位、大小和数量会影响坏死性胰腺炎的预后吗?- 前瞻性分析。
IF 1.7
Emergency Radiology Pub Date : 2024-10-01 Epub Date: 2024-07-12 DOI: 10.1007/s10140-024-02261-x
Suprabhat Giri, Swati Das, Prashanthi Nemani, Subrat Kumar Mohanty, Preetam Nath, Vedavyas Mohapatra
{"title":"Does the site, size, and number of necrotic collections affect the outcome of necrotizing pancreatitis? - a prospective analysis.","authors":"Suprabhat Giri, Swati Das, Prashanthi Nemani, Subrat Kumar Mohanty, Preetam Nath, Vedavyas Mohapatra","doi":"10.1007/s10140-024-02261-x","DOIUrl":"10.1007/s10140-024-02261-x","url":null,"abstract":"<p><strong>Purpose: </strong>In patients with acute necrotizing pancreatitis (ANP), the site, size, and the number of acute necrotic collections (ANC) may determine the outcome of patients. The current study aimed to correlate the nature of ANC with the adverse outcomes in ANP patients.</p><p><strong>Methods: </strong>This was a single-center, prospective study (August 2019-August 2022) recruiting patients with ANP, correlating the site, size, and number of ANC with the length of hospital stay, intensive care unit (ICU) stays, development of organ failure and infection, need for intervention, and mortality.</p><p><strong>Results: </strong>A total of 114 patients (mean age: 37.3 ± 13.4 years, 85.1% males) with ANP were included in the study. The number and maximum diameter of collections significantly correlated with the length of the hospital and ICU stay and the need for intervention. Taking a cut-off size of 8 cm, the sensitivity and specificity for predicting the need for intervention were 82.7% and 74.2%, respectively. ANCs located in the perinephric, paracolic, subhepatic, and epigastric regions had a significant correlation with two or more adverse outcomes. Additional points were added to the modified CT severity index (mCTSI) based on the present study's findings. The new score had significantly higher AUROC than mCTSI for predicting infection, need for intervention, ICU stay > 1 week, and mortality.</p><p><strong>Conclusion: </strong>The site, size, and number of EPNs have a significant correlation with adverse clinical outcomes in patients with ANP. The inclusion of these parameters, along with present scoring systems, will help further improve the prognostication of patients.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141589943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of night-float shifts on cognitive function among radiology residents. 夜班对放射科住院医生认知功能的影响。
IF 1.7
Emergency Radiology Pub Date : 2024-10-01 Epub Date: 2024-07-24 DOI: 10.1007/s10140-024-02269-3
Carl C Flink, Robert E Hobohm, Bin Zhang, Deborah L Jacobson, Eric B England
{"title":"Effects of night-float shifts on cognitive function among radiology residents.","authors":"Carl C Flink, Robert E Hobohm, Bin Zhang, Deborah L Jacobson, Eric B England","doi":"10.1007/s10140-024-02269-3","DOIUrl":"10.1007/s10140-024-02269-3","url":null,"abstract":"<p><strong>Background: </strong>Many radiology programs utilize a night-float system to mitigate the effects of fatigue, improve patient care, and provide faster report turnaround times. Prior studies have demonstrated an increase in discrepancy rates during night-float shifts.</p><p><strong>Objectives: </strong>This study was performed to examine the effects of night-float shift work on radiology resident cognition. We hypothesized that there would be diminished cognitive function on testing following night-float shifts when compared to testing following day shifts.</p><p><strong>Methods: </strong>Diagnostic radiology residents in their second to fifth years of residency at a single institution were recruited to participate in this pilot study. Cognitive function was evaluated using the Lumosity Neurocognitive Performance Tests (NCPT), standardized performance tests that provide real-time, objective measurements of cognitive function. Study participants completed the NCPT in 5 sessions following 5 consecutive day shifts to evaluate their baseline cognitive function. The tests were re-administered at the end of consecutive night-float shifts to assess for any changes. Sleep was objectively monitored using actigraphy devices worn around the wrist during all study weeks. Descriptive and summary statistics were performed.</p><p><strong>Results: </strong>23 prospectively recruited diagnostic radiology residents working night-float shifts took a mean 13.6 (± 5.1) neurocognitive performance tests during the study period. There was a statistically significant decline in 2 of the 6 cognitive tests administered, signifying a decrease in attention, speed, and complex reasoning ability. Night-float shifts were significantly longer than the day shifts and associated with a significantly higher study volume and cross-sectional study volume. Fitbit data demonstrated that there were no significant differences in level of activity while awake. However, participants slept significantly longer during day shifts.</p><p><strong>Conclusions: </strong>A sample of 23 radiology residents working night-float shifts demonstrated declines in attention, speed, and complex reasoning ability following sequential administration of standardized neurocognitive performance tests. While the sample size is small, these findings demonstrate the potential deleterious effects of night-float shift work and provide evidence to support further inquiry into this phenomenon.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11436431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141751363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Full head-to-head comparison of ultrasonography and CT scan in volumetric quantification of pleural effusion: a systematic review and meta-analysis. 在胸腔积液的体积定量方面,对超声波和 CT 扫描进行头对头的全面比较:系统回顾和荟萃分析。
IF 1.7
Emergency Radiology Pub Date : 2024-10-01 Epub Date: 2024-06-28 DOI: 10.1007/s10140-024-02252-y
Saeed Mohammadzadeh, Alisa Mohebbi, Iman Kiani, Afshin Mohammadi
{"title":"Full head-to-head comparison of ultrasonography and CT scan in volumetric quantification of pleural effusion: a systematic review and meta-analysis.","authors":"Saeed Mohammadzadeh, Alisa Mohebbi, Iman Kiani, Afshin Mohammadi","doi":"10.1007/s10140-024-02252-y","DOIUrl":"10.1007/s10140-024-02252-y","url":null,"abstract":"<p><p>Pleural effusion is a very common clinical finding. Quantifying pleural effusion volume and its response to treatment over time has become increasingly important for clinicians, which is currently performed via computed tomography (CT) or drainage. To determine and compare ultrasonography (US), CT, and drainage agreements in pleural effusion volumetry. Protocol pre-registration was performed a priori at ( https://osf.io/rnugd/ ). We searched PubMed, Web of Science, Embase, and Cochrane Library for studies up to January 7, 2024. Risk of bias was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2), QUADAS-C, and Consensus-based Standards for the selection of health Measurement Instruments (COSMIN). Volumetric performances of CT, US, and drainage in assessment of pleural effusion volume were evaluated through both aggregated data (AD) and individual participant data (IPD) analyses. Certainty of evidence was evaluated using Grading of Recommendations, Assessment, Development, and Evaluations (GRADE). Six studies were included with 446 pleural effusion lesions. AD results showed a perfect level of agreement with pooled Pearson correlation and intraclass correlation coefficient (ICC) of 0.933 and 0.948 between US and CT. IPD results demonstrated a high level of agreement between US and CT, with Finn's coefficient, ICC, concordance correlation coefficient (CCC), and Pearson correlation coefficient values of 0.856, 0.855, 0.854, and 0.860, respectively. Also, both results showed an overall perfect level of agreement between US and drainage. As for comparing the three combinations, US vs. CT and US vs. drainage were both superior to CT vs. drainage, suggesting the US is a good option for pleural effusion volumetric assessment. Ultrasound provides a highly reliable, to-the-point, cost-effective, and noninvasive method for the assessment of pleural effusion volume and is a great alternative to CT or drainage.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the impact of trained Radiologist Assistants in a busy emergency teleradiology practice: a comprehensive evaluation. 评估经过培训的放射科助理在繁忙的急诊远程放射学实践中的影响:一项综合评估。
IF 1.7
Emergency Radiology Pub Date : 2024-10-01 Epub Date: 2024-07-11 DOI: 10.1007/s10140-024-02264-8
Muktha Rawath R, Anjali Agrawal, Arjun Kalyanpur
{"title":"Assessing the impact of trained Radiologist Assistants in a busy emergency teleradiology practice: a comprehensive evaluation.","authors":"Muktha Rawath R, Anjali Agrawal, Arjun Kalyanpur","doi":"10.1007/s10140-024-02264-8","DOIUrl":"10.1007/s10140-024-02264-8","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to study the feasibility and usefulness of trained Radiologist Assistants in a busy emergency teleradiology practice.</p><p><strong>Method: </strong>This is a retrospective study over a 21-month period (January 2021 to September 2022). The study analysed archived data from 247118 peer review studies performed by Radiologist Assistants (RAs) out of a total case volume of 828526 and evaluated the rate of discrepancies, the study types commonly noted to have discrepancies, and the severity of errors. These missed findings were brought to the attention of the radiologists for approval and further decision-making.</p><p><strong>Results: </strong>Peer review by RAs was performed on 30% (n = 247118) of the total volume 828526 studies reported, and yielded additional findings including but not limited to fractures (218; 23%), hemorrhage,(94; 10%) pulmonary thromboembolism, (n = 104; 11%), Calculus (n = 75; 8%) lesion (n = 66; 5%), appendicitis(n = 50; 4%) and others. These were brought to the attention of the radiologist, who agreed in 97% (1279 out of 1318) of cases, and communicated the same to the referring facility, with an addended report.</p><p><strong>Conclusion: </strong>Trained RAs can provide value to the peer review program of a busy teleradiology practice and decrease errors. This may be useful to meet the ongoing radiologist shortages.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors affecting radiation dose, radiation exposure time and procedural time in arterial embolization for active hemorrhage. 影响动脉栓塞治疗活动性出血的辐射剂量、辐射照射时间和手术时间的因素。
IF 1.7
Emergency Radiology Pub Date : 2024-10-01 Epub Date: 2024-07-03 DOI: 10.1007/s10140-024-02262-w
Youssef Ghosn, Mihran Khdhir, Yara Jabbour, David Dushfunian, Iyad Kobeissi, Nada Abbas, Chantal Akkari, Eva-Maria Kahwaji, Nadim Muallem
{"title":"Factors affecting radiation dose, radiation exposure time and procedural time in arterial embolization for active hemorrhage.","authors":"Youssef Ghosn, Mihran Khdhir, Yara Jabbour, David Dushfunian, Iyad Kobeissi, Nada Abbas, Chantal Akkari, Eva-Maria Kahwaji, Nadim Muallem","doi":"10.1007/s10140-024-02262-w","DOIUrl":"10.1007/s10140-024-02262-w","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate patient and procedure-related factors contributing to the radiation dose, cumulative fluoroscopy time (CFT), and procedural time (PT) of Arterial Embolization (AE) for suspected active bleeding.</p><p><strong>Methods: </strong>Data on patients who underwent AE for suspected bleeding was retrospectively gathered between January 2019 and April 2022. Data collected included the dependent variables consisting of dose-area product (DAP), CFT, PT, and independent variables consisting of demographic, bleeding-specific, and procedure-specific parameters. All statistical computations were performed in SPSS statistics. The alpha value was set at 0.05.</p><p><strong>Results: </strong>Data from a total of 148 AE were collected with an average patient's age of 61.06 ± 21.57 years. Higher DAP was independently associated with male sex (p < 0.002), age ranges between 46 and 65 years (p = 0.019) and > 66 years (p = 0.027), BMI above 30 (p = 0.016), attending with less than 10 years of experience (p = 0.01), and bleeding in the abdomen and pelvis (p = 0.027). Longer CFT was independently associated with attending with less than 10 years of experience (p < 0.001), having 2 (p = 0.004) or > 3 (p = 0.005) foci of bleed, and age between 46 and 65 years (p = 0.007) and ≥ 66 years (p = 0.017). Longer PT was independently associated with attending with less than 10 years of experience (p < 0.001) and having 2 (p = 0.014) or > 3 (p = 0.005) foci of bleed.</p><p><strong>Conclusion: </strong>The interventionist experience influenced radiation dose, CFT and PT. Dose was also affected by patients' sex, age, BMI, as well as bleeding location. CFT was also affected by patients' age, and both CFT and PT were also affected by the number of bleeding foci. These findings highlight the multifaceted factors that affect radiation dose and procedural time, emphasizing the importance of interventionist expertise, patient's age, sex, BMI, location and number of bleeds.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141491332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brain microbleeds resulting from presumed extensive fat emboli in a patient with bone marrow necrosis following a sickle cell disease vaso-occlusive crisis. 一名镰状细胞病血管闭塞危象后骨髓坏死的患者因推测的广泛脂肪栓塞导致脑微小出血。
IF 1.7
Emergency Radiology Pub Date : 2024-09-28 DOI: 10.1007/s10140-024-02283-5
Gary Amseian, Maria Ortiz-Fernández, Pamela Doti, Anna Massuet, Pedro Castro, Camilo Pineda
{"title":"Brain microbleeds resulting from presumed extensive fat emboli in a patient with bone marrow necrosis following a sickle cell disease vaso-occlusive crisis.","authors":"Gary Amseian, Maria Ortiz-Fernández, Pamela Doti, Anna Massuet, Pedro Castro, Camilo Pineda","doi":"10.1007/s10140-024-02283-5","DOIUrl":"https://doi.org/10.1007/s10140-024-02283-5","url":null,"abstract":"<p><p>Acute manifestations of sickle cell disease (SCD) are numerous and multisystemic. Cerebral fat embolism (CFE) is a rare but serious complication of SCD caused by bone marrow necrosis (BMN) during vaso-occlusive crises (VOC). We present the case of a 41-year-old man with SCD who developed severe VOC and multi-organ dysfunction. He subsequently experienced neurological deterioration with decreased consciousness and diffuse encephalopathy on serial electroencephalograms. Bone marrow aspiration confirmed BMN. Brain MRI revealed extensive diffuse leukoencephalopathy, vasogenic and cytotoxic edema in the white matter, patchy edema in the cranial vault bone marrow on fat-suppressed FLAIR sequence (a finding consistent with the confirmed BMN), and multiple cerebral microbleeds on susceptibility-weighted imaging consistent with CFE. The management of acute neurological complications of SCD varies depending on the specific complication. Brain MRI plays a crucial role in the accurate diagnosis of these complications to guide appropriate treatment.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amyloid related imaging abnormalities in the emergency setting. 急诊中与淀粉样蛋白相关的成像异常。
IF 1.7
Emergency Radiology Pub Date : 2024-09-27 DOI: 10.1007/s10140-024-02286-2
Jan Czerminski, Supriya Khatri, Balaji Rao
{"title":"Amyloid related imaging abnormalities in the emergency setting.","authors":"Jan Czerminski, Supriya Khatri, Balaji Rao","doi":"10.1007/s10140-024-02286-2","DOIUrl":"https://doi.org/10.1007/s10140-024-02286-2","url":null,"abstract":"<p><p>Since the 2021 FDA approval of the first monoclonal antibody (MAB) therapy for Alzheimer's disease (AD), treatment has progressed from symptom management to targeting and reducing amyloid β plaque burden. While these therapies offer hope of altering the disease course, they come with risks, such as amyloid-related imaging abnormalities (ARIA), which include ARIA-E (edema and effusion) and ARIA-H (hemorrhage). This report details the case of a 64-year-old woman undergoing donanemab treatment who developed severe ARIA, characterized by extensive vasogenic edema and multiple microhemorrhages. The increasing use of MABs necessitates heightened awareness and expertise among emergency radiologists to identify findings of ARIA effectively, ensuring timely and appropriate care for patients undergoing these novel therapies.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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