Paediatric respiratory physiology and sleep最新文献_第9页

Variability of tidal breathing parameters in preterm infants and associations with respiratory morbidity during the first year of life: a cohort-study 早产儿潮汐呼吸参数的变异性及其与生命第一年呼吸道疾病的关系:一项队列研究

Paediatric respiratory physiology and sleep Pub Date : 2018-09-15 DOI: 10.1183/13993003.congress-2018.OA3591

J. Usemann, A. Suter, E. Zannin, E. Proietti, S. Fouzas, S. Schulzke, P. Latzin, U. Frey

{"title":"Variability of tidal breathing parameters in preterm infants and associations with respiratory morbidity during the first year of life: a cohort-study","authors":"J. Usemann, A. Suter, E. Zannin, E. Proietti, S. Fouzas, S. Schulzke, P. Latzin, U. Frey","doi":"10.1183/13993003.congress-2018.OA3591","DOIUrl":"https://doi.org/10.1183/13993003.congress-2018.OA3591","url":null,"abstract":"Objectives: Low variability of tidal volume (V T ) and capnographic indices in preterm infants is an expression of impaired lung function and gas exchange. We tested if these parameters, when assessed near term, are predictive of respiratory morbidity during the first year of life. Methods: We performed lung function measurements at 44 weeks postmenstrual age in a birth cohort of 133 unsedated preterm infants. We asked whether lung function measurements (variability of V T and capnographic indices) are associated with subsequent rehospitalization, episodes of wheeze, or inhalation therapy. Using logistic regression and area under the curve (AUC) analysis, we determined if the predictive power of models that included BPD classification is enhanced by adding variability of V T or capnographic indices. Results: Both coefficient of variation (CV) of V T (CV VT ) (range 4%-35%) and CV of expired CO 2 volume (CV VE,CO2 ) (range 5%-40%) were negatively associated with rehospitalization during infancy. Per interquartile range decrease in CV VT and CV VE , CO2 , the adjusted odds ratio (95% CI) for rehospitalization increased by 2.25 (1.21–4.20) and 2.31 (1.20–4.45), respectively. Adding CV VT or CV VE,CO2 to ROC models that included BPD improved prediction of rehospitalization (AUC increased from 0.56 to 0.66 in both models). There was no association of CV VT or capnographic indices with other outcomes. Conclusion: In comparison to BPD classification alone, including near term variability of tidal breathing parameters improves prediction of rehospitalization in infancy. These findings may impact upon parent counseling and monitoring strategies in preterm infants.","PeriodicalId":116156,"journal":{"name":"Paediatric respiratory physiology and sleep","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124874784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Comparison of bronchodilator responsiveness between forced oscillation technique and spirometry 强迫振荡技术与肺活量测定法对支气管扩张剂反应性的比较

Paediatric respiratory physiology and sleep Pub Date : 2018-09-15 DOI: 10.1183/13993003.CONGRESS-2018.PA4573

E. Lauhkonen, S. Sivagnanasithiyar, G. Kaltsakas, R. Iles

{"title":"Comparison of bronchodilator responsiveness between forced oscillation technique and spirometry","authors":"E. Lauhkonen, S. Sivagnanasithiyar, G. Kaltsakas, R. Iles","doi":"10.1183/13993003.CONGRESS-2018.PA4573","DOIUrl":"https://doi.org/10.1183/13993003.CONGRESS-2018.PA4573","url":null,"abstract":"Aims: Forced oscillation technique (FOT) may provide a different aspect of lung mechanics compared to spirometry. We aimed to clarify discrepancies in bronchodilator responsiveness (BDR) results between FOT and spirometry in a clinical audit. Methods: Data were available for analysis in 54 subsequent FOT and spirometry BDR measurements in sequentially recruited 3-17 years old asthmatic children. Results BDR tests were in agreement in 87% (47/54): two cases (3.7%) were negative in spirometry but positive in FOT, and 5 (9.3%) positive in spirometry but negative in FOT (Figure 1). There was no statistical difference in age, sex, ethnicity, height, weight or BMI between cases with test agreement and disagreement. Use of bronchodilator (tiotropium+/-SABA/LABA) before the BDR testing was present in 71% (5/7) of the outliers vs. 17% (8/47) in those with test agreement (p=0.002). Conclusion: We found a good agreement of BDR between the two techniques. In case of test-to-test discrepancy, bronchodilator use before BDR testing may be a confounding factor in children with asthma. Figure 1 Scatterplot of baseline to post-bronchodilator spirometry FEV1 (%-baseline) against FOT Rrs8 (%-pred).","PeriodicalId":116156,"journal":{"name":"Paediatric respiratory physiology and sleep","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125152167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional dead space in children with cystic fibrosis or primary ciliary dyskinesia. 囊性纤维化或原发性纤毛运动障碍患儿的功能性死亡空间。

Paediatric respiratory physiology and sleep Pub Date : 2018-09-15 DOI: 10.1183/13993003.congress-2018.pa564

F. Singer, B. Stettler, J. Wolfensberger, I. Korten, C. Casaulta, Sylvia Nyilas, Cordula Koerner Rettberg, K. Ramsey, P. Latzin

引用次数: 0

Assessment of respiratory function in adolescents with idiopathic scoliosis treated with brace. 用支具治疗青少年特发性脊柱侧凸的呼吸功能评估。

Paediatric respiratory physiology and sleep Pub Date : 2018-09-15 DOI: 10.1183/13993003.CONGRESS-2018.PA4580

A. Papadopoulou, Katerina Mikelatou, A. Boutis, E. Tsafantakis, D. Mermiri

引用次数: 0

Lingual frenulum evaluation in school age children with and without sleep disordered breathing 有无睡眠呼吸障碍的学龄儿童舌系带评价

Paediatric respiratory physiology and sleep Pub Date : 2018-09-15 DOI: 10.1183/13993003.CONGRESS-2018.OA3588

M. Evangelisti, M. Barreto, Manuela Cecili, Emanuela Scopelliti, M. Villa

{"title":"Lingual frenulum evaluation in school age children with and without sleep disordered breathing","authors":"M. Evangelisti, M. Barreto, Manuela Cecili, Emanuela Scopelliti, M. Villa","doi":"10.1183/13993003.CONGRESS-2018.OA3588","DOIUrl":"https://doi.org/10.1183/13993003.CONGRESS-2018.OA3588","url":null,"abstract":"Background: A recent study suggested that the presence of short lingual frenulum could be a “new phenotype” for paediatric sleep apnoea. Aims: In an epidemiological study we analyzed the presence of short lingual frenulum related to sleep disordered breathing (SDB) in school age children. Methods: We studied 504 school age children. Sleep clinical record (SCR) was obtained for all children. Moreover every child received orthodontic and lingual frenulum evaluation. Tongue strength, tongue peak pressure and endurance, using the Iowa Oral Performance Instrument (IOPI), were obtained in all patients. Results: We evaluated 504 children, mean age 9.6 ± 2.3 years, 277 were male. Forty-two children (8.3 %) obtained a positive SCR. Short lingual frenulum was found in 114 (22.6%) children. Children with short lingual frenulum, when compared to children with normal lingual frenulum, had a higher prevalence of male gender (54.4 vs 41%, p= 0.01), SDB (15.4 vs 6.1 %, p=0.003) and dento-skeletal malocclusions (67.5 vs 42.8%, p=0.0001). Moreover children with SDB and short lingual frenulum showed lower tongue strength measured by IOPI when compared to children without SDB (42.6±9.6 vs 47.2±10.4, p=0.04). Children with malocclusion and short lingual frenulum showed an higher odds ratio for the presence of obstructive sleep apnea (OSA) related symptoms [p Conclusion: A short lingual frenulum, associated with dento-skeletal malocclusion, is a major risk factor for SDB in school age children. An early multidisciplinary approach, including lingual frenulum evaluation, should be conducted for screening SDB.","PeriodicalId":116156,"journal":{"name":"Paediatric respiratory physiology and sleep","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129123674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Short- and mid-term reproducibility of lung clearance index in children with cystic fibrosis and healthy controls 囊性纤维化患儿与健康对照者肺清除率指数的中短期可重复性

Paediatric respiratory physiology and sleep Pub Date : 2018-09-15 DOI: 10.1183/13993003.congress-2018.pa4582

B. Frauchiger, Sylvia Nyilas, K. Ramsey, P. Latzin, S. Yammine

引用次数: 0

Glutathione s-transferase genotype determines lung function deficits from infancy to adulthood in those with in utero tobacco exposure 谷胱甘肽s-转移酶基因型决定子宫内烟草暴露者从婴儿期到成年期的肺功能缺陷

Paediatric respiratory physiology and sleep Pub Date : 2018-09-15 DOI: 10.1183/13993003.CONGRESS-2018.OA3586

L. Owens, I. Laing, J. Murdzoska, Guicheng Zhang, P. Lesouëf

引用次数: 1

Feasibility of specific ventilation imaging using oxygen enhanced magnetic resonance imaging (OEMRI) in adolescents. 氧增强磁共振成像(OEMRI)在青少年特定通气成像的可行性。

Paediatric respiratory physiology and sleep Pub Date : 2018-09-15 DOI: 10.1183/13993003.CONGRESS-2018.PA563

R. Jayasuriya, T. Walker, R. Sá, P. Robinson, G. King, K. Prisk, Rebecca J. Theilman, E. Coward, B. Kennedy, H. Selvadurai

引用次数: 0

Diagnosis of peripheral obstructive pattern in children 儿童外周梗阻的诊断

Paediatric respiratory physiology and sleep Pub Date : 2018-09-15 DOI: 10.1183/13993003.congress-2018.pa555

N. Beydon, E. Dufetelle

引用次数: 0

A transition evening is a popular and effective way to deliver high quality transition in respiratory paediatrics 过渡夜是呼吸儿科提供高质量过渡的一种流行和有效的方法

Paediatric respiratory physiology and sleep Pub Date : 2018-09-15 DOI: 10.1183/13993003.CONGRESS-2018.PA4584

A. Scott, E. Sheppard, N. Butler, A. Critchlow

引用次数: 0