Endoscopic Ultrasound最新文献

{"title":"EUS-radiofrequency ablation for pancreatic neuroendocrine tumors: Is there a promising future?","authors":"Sahib Singh, Vishnu Charan Suresh Kumar, Douglas G Adler","doi":"10.1097/eus.0000000000000083","DOIUrl":"10.1097/eus.0000000000000083","url":null,"abstract":"","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"13 6","pages":"323-324"},"PeriodicalIF":4.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A suspected case of hepatic reactive lymphoid hyperplasia in which EUS-fine needle aspiration contributed to the diagnosis.","authors":"Yuya Sato, Tsuyoshi Suda, Yasunori Sato, Kiichiro Kaji, Shuichi Terasaki","doi":"10.1097/eus.0000000000000092","DOIUrl":"10.1097/eus.0000000000000092","url":null,"abstract":"","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"13 6","pages":"379-381"},"PeriodicalIF":4.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723669/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EUS-guided fine-needle biopsy <i>versus</i> fine-needle aspiration for histopathological evidence for type 1 autoimmune pancreatitis: A single-center retrospective study in China.","authors":"Yuyan Zhou, Liqi Sun, Xinyue Wang, Dongling Wan, Jiaheng Xu, Mengruo Jiang, Yue Liu, Chao Liu, Yatao Tu, Haojie Huang, Zhendong Jin","doi":"10.1097/eus.0000000000000095","DOIUrl":"10.1097/eus.0000000000000095","url":null,"abstract":"<p><strong>Background and objectives: </strong>EUS is recommended for guiding pancreatic tissue acquisition in suspected autoimmune pancreatitis (AIP) cases. However, there is a lack of comparative research on the effectiveness between EUS-guided fine-needle aspiration (EUS-FNA) and EUS-guided fine-needle biopsy (EUS-FNB) for diagnosing AIP in China. This study aimed to evaluate the diagnostic accuracy of EUS-guided tissue acquisition (EUS-TA) specifically for type 1 AIP.</p><p><strong>Methods: </strong>Between 2010 and 2023, individuals with AIP who received EUS-TA at Changhai Hospital were included in the study.</p><p><strong>Results: </strong>A total of 173 patients diagnosed with AIP who underwent EUS-TA were included in the final analysis. Of these, 104 patients (60.1%) received EUS-FNA, and 69 patients (39.9%) underwent EUS-FNB. Sufficient pancreatic tissue samples (>5 cells/high-power field) were obtained in 164 of 173 patients (94.8%), with success rates of 94.2% for EUS-FNA and 95.7% for EUS-FNB (<i>P ></i> 0.05). EUS-FNB exhibited higher rates of reliable level 1 histopathological findings (40.9% <i>vs.</i> 16.3%, <i>P</i> < 0.001) and reliable level 2 histopathological findings (33.3% <i>vs</i>. 12.2%, <i>P</i> < 0.001) compared with EUS-FNA. Furthermore, a higher occurrence of IgG4-positive plasma cell infiltration (>10 cells/high-power field) was observed with EUS-FNB compared with EUS-FNA (74.2% <i>vs</i>. 27.9%, <i>P</i> < 0.001). The multivariate logistic analysis also revealed that EUS-FNA was less effective in obtaining reliable evidence compared with EUS-FNB, as evident in both level 2 (<i>P</i> = 0.002; odds ratio, 0.21; 95% confidence interval, 0.08-0.56) and level 1 (<i>P</i> = 0.001; odds ratio, 0.19; 95% confidence interval, 0.08-0.49) histopathological evidence.</p><p><strong>Conclusions: </strong>EUS-FNB demonstrates higher rates of level 1 and level 2 histopathological findings, as well as more abundant IgG4-positive plasma cell infiltration, compared with EUS-FNA.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"13 6","pages":"351-360"},"PeriodicalIF":4.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EUS-guided cyanoacrylate glue injection for the management of refractory bleeding from postglue ulcer following gastric varices treatment (with video).","authors":"Wei Tan, Jiaqi Sheng, Ziyin Huang, Mingkai Chen","doi":"10.1097/eus.0000000000000090","DOIUrl":"10.1097/eus.0000000000000090","url":null,"abstract":"","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"13 6","pages":"382-384"},"PeriodicalIF":4.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful EUS-guided fine-needle biopsy using a forward-viewing echoendoscope for local recurrence at the choledochojejunal anastomotic site 13 years after pancreaticoduodenectomy for cholangiocarcinoma.","authors":"Akihiko Kida, Jun Asai, Tatsuya Yamashita, Takeshi Urabe, Taro Yamashita","doi":"10.1097/eus.0000000000000096","DOIUrl":"10.1097/eus.0000000000000096","url":null,"abstract":"","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"13 6","pages":"376-378"},"PeriodicalIF":4.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adequacy of EUS-guided fine-needle aspiration and fine-needle biopsy for next-generation sequencing in pancreatic malignancies: A systematic review and meta-analysis.","authors":"Yundi Pan, Taojing Ran, Xianda Zhang, Xianzheng Qin, Yao Zhang, Chunhua Zhou, Duowu Zou","doi":"10.1097/eus.0000000000000097","DOIUrl":"10.1097/eus.0000000000000097","url":null,"abstract":"<p><strong>Background and objectives: </strong>A majority of pancreatic malignancies are unresectable at the time of presentation and require EUS-guided fine-needle aspiration or fine-needle biopsy (EUS-FNA/FNB) for diagnosis. With the advent of precision therapy, there is an increasing need to use EUS-FNA/FNB sample for genetic analysis. Next-generation sequencing (NGS) is a preferred technology to detect genetic mutations with high sensitivity in small specimens. We performed a meta-analysis to evaluate the adequacy of EUS-FNA/FNB for NGS in pancreatic malignancies.</p><p><strong>Methods: </strong>PubMed, Embase, Cochrane Library, and Web of Science were searched from database inception to November 11, 2023. The primary outcome was the proportion of sufficient sample acquired by EUS-FNA/FNB in pancreatic malignancies for NGS. Secondary outcomes were the proportion of sufficient sample for NGS in pancreatic ductal adenocarcinoma (PDAC) and the detection rates of mutations in KRAS, TP53, CDKN2A, and SMAD4 and actionable mutations in PDAC. The pooled proportions were calculated using a random-effects model. Potential sources of heterogeneity were investigated with subgroup analyses and meta-regression.</p><p><strong>Results: </strong>Twenty studies with 881 samples were included. The pooled adequacy of EUS-FNA/FNB sample for NGS was 89.9% (95% CI, 80.8%-96.7%) in pancreatic malignancies and 92.0% (95% CI, 81.3%-98.8%) in PDAC. Screening sample suitability before NGS testing was associated with lower adequacy in subgroup analysis (79.7% <i>vs.</i> 98.4%, <i>P</i> = 0.001). The pooled prevalences of mutations in KRAS, TP53, CDKN2A, and SMAD4 in PDAC were 87.4% (95% CI, 83.2%-91.2%), 62.6% (95% CI, 53.2%-71.7%), 20.6% (95% CI, 11.9%-30.8%), and 19.4% (95% CI, 11.2%-29.1%), respectively. The pooled prevalence of potentially actionable mutations in PDAC was 14.5% (95% CI, 8.2%-22.0%).</p><p><strong>Conclusions: </strong>In the majority of cases, EUS-FNA/FNB can acquire adequate sample for NGS and identify tumor-specific mutations in patients with pancreatic malignancies. Strict pre-analysis screening criteria may negatively impact the sample adequacy and the success rate for NGS.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"13 6","pages":"366-375"},"PeriodicalIF":4.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of EUS-guided through-the-needle biopsy in the diagnosis of pancreatic cystic neoplasms: An 8-year experience.","authors":"Bingqian Cheng, Chen Du, Zhengting He, Xiuxue Feng, Huikai Li, Zhanbo Wang, Fei Gao, Yunyun Zhao, Ningli Chai, Enqiang Linghu","doi":"10.1097/eus.0000000000000091","DOIUrl":"10.1097/eus.0000000000000091","url":null,"abstract":"<p><strong>Background and objectives: </strong>An accurate diagnosis is crucial for the clinical management of pancreatic cystic neoplasm (PCN). EUS-guided through-the-needle biopsy (EUS-TTNB) is a novel technique for improving the accuracy of PCN diagnosis. There is insufficient evidence about the efficacy of EUS-TTNB. This study aims to evaluate the feasibility and diagnostic performance of EUS-TTNB for PCN.</p><p><strong>Methods: </strong>Between June 2015 and July 2023, we prospectively enrolled 454 patients with a clinical concern for PCN in our database. After excluding those diagnosed with pancreatic cancer, pseudocysts, or other no-neoplasms, we assessed 326 patients with 329 cysts undergoing EUS-guided fine-needle-aspiration (EUS-FNA) or EUS-TTNB for evaluation. The primary indicators were tissue acquisition yield and diagnostic yield. The cyst characteristics (size, location, the presence of septation, mural nodule, and solid mass) and the number of biopsy samples were chosen for the analysis of factors associated with diagnostic performance.</p><p><strong>Results: </strong>There were 220 (67.5%) females and 106 (32.5%) males, and the median patient age was 50 years (range, 18-88). There were 329 cysts sampled by FNA and 143 by TTNB. The median cyst size was 31.5 mm (range, 6.9-114.0). The diagnostic yields of FNA and TTNB were 35.7% (112/314) and 57.5% (73/127), respectively (<i>P</i> < 0.001). Special cyst types were diagnosed by TTNB in 58 (45.7%, 58/127) cysts, 19 of which had surgical pathology. Fifteen of 19 TTNB diagnoses were concordant with the surgical pathology.</p><p><strong>Conclusion: </strong>EUS-TTNB is an option to improve the diagnosis of PCN. Standardized procedures and appropriate indications for TTNB need to be studied.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"13 6","pages":"345-350"},"PeriodicalIF":4.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endobronchial ultrasound-guided transbronchial tunnel Cryobiopsy for mediastinal lymphadenopathy (with video).","authors":"Mingming Deng, Run Tong, Ziwen Zheng, Gang Hou","doi":"10.1097/eus.0000000000000063","DOIUrl":"10.1097/eus.0000000000000063","url":null,"abstract":"","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"13 5","pages":"314-316"},"PeriodicalIF":4.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144093182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EUS-led breakthrough: An innovative journey to overcome complete gastric outlet obstruction by gastroenterostomy (with video).","authors":"Yuanyuan Yang, Mingmei Ye, Xiaoyan Wang, Li Tian","doi":"10.1097/eus.0000000000000088","DOIUrl":"10.1097/eus.0000000000000088","url":null,"abstract":"","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"13 5","pages":"320-322"},"PeriodicalIF":4.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144093184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of biliary-pancreatic double stents on EUS-guided tissue acquisition among patients with solid pancreatic lesions: A multicenter study.","authors":"Guochen Shang, Qi He, Chaoqun Han, Xianwen Guo, Weigang Chen, Zhen Ding, Rong Lin","doi":"10.1097/eus.0000000000000082","DOIUrl":"10.1097/eus.0000000000000082","url":null,"abstract":"<p><strong>Background and objective: </strong>Although the impact of biliary stents on the accuracy of EUS-guided tissue acquisition (EUS-TA) is still controversial, the influence of biliary-pancreatic double stents on EUS-TA is even more inconclusive. The aim of the study was to determine whether the diagnostic yield of EUS-FNA in the diagnosis of solid pancreatic lesions will be affected after placement of biliary-pancreatic double stents.</p><p><strong>Methods: </strong>A multicenter retrospective study including patients who underwent EUS-FNA with biliary duct obstruction was performed. Patients were divided into 2 groups according to whether there were biliary-pancreatic double stents before EUS-FNA. The patients' EUS-FNA report, histopathological results, and clinical case data were reviewed and compared.</p><p><strong>Results: </strong>Ninety-two patients were included, 42 with biliary-pancreatic double stents and 50 without any stents. The puncture time taken by EUS-FNA was significantly longer in the stent group than the no-stent group (19 <i>vs.</i> 15 min, <i>P</i> < 0.001). No significant differences were observed in accuracy (90.5% <i>vs.</i> 94%), sensitivity (89.5% <i>vs.</i> 93.6%), specificity (100% <i>vs.</i> 100%), NPV (50% <i>vs.</i> 50%), PPV (100% <i>vs.</i> 100%), respectively, in both groups. Patients with larger lesions (OR = 1.600, 95% CI: 1.124-2.277) and those who required more passes had a higher diagnostic yield (OR = 9.376, 95% CI: 1.356-64.819) by multivariate analysis.</p><p><strong>Conclusions: </strong>ERCP before EUS-FNA is feasible for the treatment of solid pancreatic lesions causing obstructive jaundice. It will not have a negative impact on the diagnostic accuracy and surgical complications, but the EUS-FNA operation time will be prolonged.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"13 5","pages":"287-292"},"PeriodicalIF":4.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144093186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}