MNHMH / MNEME. Past and Memory in the Aegean Bronze Age最新文献

MEMORY AND MODERN RECEPTIONS OF THE AEGEAN BRONZE AGE 爱琴海青铜时代的记忆与现代接待

MNHMH / MNEME. Past and Memory in the Aegean Bronze Age Pub Date : 2019-06-01 DOI: 10.2307/j.ctv1q26q48.72

N. Momigliano

引用次数: 1

IN VINO VERITAS? In vino veritas ?

MNHMH / MNEME. Past and Memory in the Aegean Bronze Age Pub Date : 2019-04-09 DOI: 10.2307/j.ctv1q26q48.18

Charlotte Langohr

{"title":"IN VINO VERITAS?","authors":"Charlotte Langohr","doi":"10.2307/j.ctv1q26q48.18","DOIUrl":"https://doi.org/10.2307/j.ctv1q26q48.18","url":null,"abstract":"1991 Albert Einstein once said: “Truth is what stands the test of experience.” Earlier, cardiac derangements associated to sepsis have been ascribed to the inflammatory mediators known as myocardial depressant factors (1), coronary ischemia (2), nitric oxide excessive production (3), interstitial myocarditis (4), increased apoptosis (5), and even subcellular mechanisms involving sodium and calcium homeostasis (6). Discussions on the true involvement of the heart in sepsis and septic shock, regardless of hemodynamic conditions, date back to the early 1960s (7) when some studies already used endotoxic shock models in animals. In the 1980’s, using nuclear medicine techniques, Parker et al (8, 9) demonstrated the decreased biventricular ejection fraction in these septic patients. The connection between clinical myocardial depression and the effects of myocardial depressor substances was described by Parrillo et al (10) in the late 1980s by measuring the serum levels of the substances in these patients during the septic phase. This study established a strong tie between in vivo and in vitro observations of cardiac function and the activity of myocardial depressor substances in septic shock. In 1994, we and others (4) published the histopathological findings of the myocardium in 71 autopsies of patients who met morphological criteria of sepsis, comparing them to a control group and observing the presence of interstitial myocarditis in 27% of the sample, bacterial colonization in 11%, necrosis of cardiac fibers in 7%, and interstitial edema in 28%. Furthermore, the identification of troponin in 1999 as a reliable marker of myocardial injury in sepsis added some new insights to this complex disease (11). In this issue of Critical Care Medicine, Dr. Smeding and coworkers (12) added one more brick to this poorly understood wall. By studying the myocardial effects of resveratrol, a constituent of red wine, they could in fact document its salutary effects on myocardial energy production and mitigation of inflammation associated with sepsis by reversing sepsis-dependent downregulation of peroxisome proliferator–activated receptor  coactivator-1a. They succeeded in proving that resveratrol may in fact improve myocardial dysfunction in an experimental animal model, although we do have some major concerns. Maybe the major pitfall related to the study was their inability to document the status of the nonsurvivors group. Furthermore, mortality rate did not improve, groups did not receive classic treatment for sepsis as antibiotics and fluid resuscitation, and so this adjunctive therapeutic could not be evaluated. Ventricular function was improved in the resveratrol group, but what were the differences between the surviving and nonsurviving animals? Acting in many points, resveratrol can increase gene expression of peroxisome proliferator–activated receptor  coactivator-1a, and therefore explain myocardial protection on developing dysfunction. One could figure ou","PeriodicalId":115564,"journal":{"name":"MNHMH / MNEME. Past and Memory in the Aegean Bronze Age","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121345894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AMONG THE ANCESTORS AT AIDONIA 在艾多尼亚的祖先中

MNHMH / MNEME. Past and Memory in the Aegean Bronze Age Pub Date : 2019-04-09 DOI: 10.2307/j.ctv1q26q48.34

Lynne. Kvapil, Kim Shelton

引用次数: 0

THE PRE- AND PROTO-PALATIAL CEMETERY AT PETRAS-KEPHALA: 佩特拉斯-凯帕拉的前宫殿和原始宫殿墓地:

MNHMH / MNEME. Past and Memory in the Aegean Bronze Age Pub Date : 2019-04-09 DOI: 10.2307/j.ctv1q26q48.13

M. Tsipopoulou, D. W. Rupp

引用次数: 1

SURVIVAL OR RECYCLING? 生存还是回收?

MNHMH / MNEME. Past and Memory in the Aegean Bronze Age Pub Date : 2019-04-09 DOI: 10.2307/j.ctv1q26q48.76

Maria Emanuela Alberti

引用次数: 0

SPACE AND MNEME IN LATE BRONZE AGE MACEDONIA 青铜时代晚期马其顿的空间和记忆

MNHMH / MNEME. Past and Memory in the Aegean Bronze Age Pub Date : 2019-04-09 DOI: 10.2307/j.ctv1q26q48.64

Evangelia Stefani, N. Merousis

引用次数: 0

THE MINOAN DOUBLE VASE: 米诺斯双花瓶:

MNHMH / MNEME. Past and Memory in the Aegean Bronze Age Pub Date : 2019-04-09 DOI: 10.2307/j.ctv1q26q48.77

Sofia Antonello

引用次数: 0

CURATION IN THE BRONZE AGE AEGEAN: 青铜器时代爱琴海的策展:

MNHMH / MNEME. Past and Memory in the Aegean Bronze Age Pub Date : 2019-04-09 DOI: 10.2307/j.ctv1q26q48.51

B. Davis, E. Banou, L. Hitchcock, A. Chapin

引用次数: 0

HOMERIC ITHACA AND MYCENAEAN CEPHALONIA: 荷马时代的伊萨卡和迈锡尼时代的cephalonia;

MNHMH / MNEME. Past and Memory in the Aegean Bronze Age Pub Date : 2019-04-09 DOI: 10.2307/j.ctv1q26q48.95

Ioannis Voskos

引用次数: 0

CHOOSING AN ADEQUATE METHODOLOGICAL APPROACH AND METHODOLOGY FOR ANTIQUE OBJECTS IN ARCHAEOLOGY 为考古学中的古物选择合适的方法论方法和方法论

MNHMH / MNEME. Past and Memory in the Aegean Bronze Age Pub Date : 2019-04-09 DOI: 10.2307/j.ctv1q26q48.80

Claire Camberlein

引用次数: 0