{"title":"A COMPARATIVE QUALITY STUDY OF SELECTED AUTHORIZED AND SMUGGLED MEDICINES IN ADEN, YEMEN","authors":"E. Ali, Olfat Saleh Ahmed, Hala Shokri","doi":"10.47372/ejua-ba.2023.2.249","DOIUrl":"https://doi.org/10.47372/ejua-ba.2023.2.249","url":null,"abstract":"In Yemen, most of the medicines are imported. Drugs that enter the country by legal means undergo some tests by Supreme Board for Drugs and Medical Appliances (SBDMA) to evaluate the quality of the product. However, some medicines enter the country illegally (smuggling) and this makes them bypass the evaluation of their quality by the SBDMA. This work was carried out to determine the physical quality control parameters of authorized and smuggled drug products marketed in Aden pharmacies. The authorized and smuggled brands of cefuroxime (CEF), atorvastatin (ATR), and carvedilol (CAR) tablets available in Aden pharmacies were selected. The tablets were evaluated for their physical properties and quality control parameters including weight variation, hardness, friability, and disintegration test. The level of drug content also was evaluated using UV spectroscopy. The physical assessment showed that the authorized and smuggled brands of the same products were uniform in shape, color, packing, and labeling information except for the registration number and manufacture date which were present only on the authorized brands. The three authorized and smuggled brands of CEF, ATR, and CAR complied with the official specifications for weight version, diameter, thickness and hardness, friability, and disintegration tests except for the hardness value of ATR. All authorized brands agreed with the label claims whereas some smuggled brands contained the appropriate active ingredients but did not contain the right amounts.","PeriodicalId":11552,"journal":{"name":"Electronic Journal of University of Aden for Basic and Applied Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90809116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Ahmed Saleh Al-Lahji, Y. Issa, Hussien Mohamed Abddel-fattah
{"title":"NEW METHODS FOR DETERMINATION OF AMBROXOL HYDROCHLORIDE IN PURE FORM AND FARMACEUTICAL FORMULATIONS BASED ON SPECTROPHOTOMETRY","authors":"Mohamed Ahmed Saleh Al-Lahji, Y. Issa, Hussien Mohamed Abddel-fattah","doi":"10.47372/ejua-ba.2023.2.246","DOIUrl":"https://doi.org/10.47372/ejua-ba.2023.2.246","url":null,"abstract":"The proposed methods are simple, rapid, and accurate, used for the determination of Ambroxol Hydrochloride (AMB.HCl). There were two methods, the First method included chromotrope 2R, chromotrope 2B, arsenazo I, ASPANDS, and chromotrope 2C for the determination of AMB.HCl in its pure and pharmaceutical forms. The first method is based on the drug oxidation with Potassium permanganate in excess. The unreacted potassium permanganate was determined by measuring the absorbance of colored chromotropic acid azo dyes namely chromotrope 2R, chromotrope 2B, arsenazo I, SPADNS, and chromotrope 2C. The suitable ƛmax were 500, 510, 500, 510, and 520 nm, respectively. Under optimized conditions, Beer’s Law showed good correlation and obeyed in the concentration range 1.51-7.46, 0.82-4.97, 1.65-6.63, 0.82-6.63, and 1.73-8.29 µg mL-1 for chromotrope 2R, chromotrope 2B, arsenazo I , SPADNS, and chromotrope 2C. The apparent molar absorptivity, Sandell sensitivity, LOD, and LOQ were calculated. Pure and pharmaceutical forms containing AMB.HCl were analyzed and tested for the validity of the proposed methods. The Second method spectrophotometric titration is based on the determination of unreacted potassium permanganate using spectrophotometric titration against ferrous ammonium sulfate, where the end-point was detected spectrophotometrically using ferrion indicator at 510 nm, the Relative standard deviation where 0.23-2.04 with average recovery 100.35-103%.","PeriodicalId":11552,"journal":{"name":"Electronic Journal of University of Aden for Basic and Applied Sciences","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77711840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OPTICAL AND DIELECTRIC PROPERTIES OF EPOXY RESIN FILLED WITH TITANIUM DIOXIDE PARTICLES","authors":"M. S. Al-Salimi, Wesam R. N. Ali, Khaled M. Habeb","doi":"10.47372/ejua-ba.2023.2.250","DOIUrl":"https://doi.org/10.47372/ejua-ba.2023.2.250","url":null,"abstract":"This work studies the electrical properties for pure epoxy, and epoxy with (0, 1, 1.5, 2 wt%) titanium dioxide powder composites. The effects of titanium dioxide contents on optical and dielectrically properties of the epoxy/ titanium dioxide have investigated by several techniques were used to characterize the epoxy/titanium dioxide: UV-visible spectrophotometer reveals a new absorption band in the wavelength range (350-600) nm. The findings of this investigation show that when the proportion of titanium dioxide added increases, the absorbance increases which are ascribed to interchain interaction. The absorption coefficient (α), extinction coefficient (k), refractive index (n), the real and imaginary permittivity (εr, εi), and energy gap (Eg) of epoxy/titanium dioxide samples were effectively determined from the recorded data optical transmission technique. In addition, these epoxy have been examined in the wavenumber range (4000-500 cm-1) using an FT-IR spectrometer and also a dielectric constant measurement. The thickness of all the samples is 1.2 mm ± 0.1 mm.","PeriodicalId":11552,"journal":{"name":"Electronic Journal of University of Aden for Basic and Applied Sciences","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80797598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"تأثير إضافة مسحوق الكركم إلى عليقة دجاج اللحم على الاداء الانتاجي وبعض صفات الذبيحة","authors":"Salem Nasser Hussein, Abdel-Wahed Awad Ahmed","doi":"10.47372/ejua-ba.2023.2.248","DOIUrl":"https://doi.org/10.47372/ejua-ba.2023.2.248","url":null,"abstract":"نفذت هذه الدراسة في حظيرة الدواجن بكلية ناصر للعلوم الزراعية – جامعة عدن خلال الفترة من 3/2/2021 إلى2 /3/2021. وذلك لبحث تأثير إضافة مستويين من مسحوق الكركم في عليقة دجاج اللحم على الاداء الانتاجي وبعض مقاييس الذبيحة باستخدام عدد 90 كتكوت لحم غير مجنس من سلاسة Ross من عمر 7 – 35 يوم وزعت عشوائياً على ثلاث معاملات ( 30 كتكوت/ معاملة ) وضعت في ثلاث مكررات (10 كتاكيت / مكرر) وكانت المعاملات كما يلي: (T1) تقديم عليقة قياسية دون أية اضافات ( شاهد )، (T2) تقديم عليقة قياسية مع إضافة 0.25% مسحوق كركم، (T3) تقديم عليقة قياسية مع إضافة 0.5% مسحوق كركم. اظهرت النتائج تفوقاً معنويا (P<0.05) للمعاملتين الثانية والثالثة في صفات وزن الجسم، الزيادة الوزنية وكفاءة التحويل الغذائي مقارنة مع المعاملة الأولى، وتفوق معنوي (P<0.05) للمعاملة الثالثة على المعاملة الثانية في صفات وزن الجسم والزيادة الوزنية، وزيادة معنوية (P<0.05) في نسبة تصافي الذبيحة للمعاملتين الأولى والثالثة مقارنة مع المعاملة الثانية. في حين لم تظهر أي اختلافات معنوية بين المعاملات في صفات استهلاك العلف والنسبة المئوية لقطع (الصدر والفخذان) والاحشاء الصالحة للأكل (الكبد والقلب والقانصة) منسوبة إلى وزن الجسم قبل الذبح. نستنتج من هذه الدراسة بأن إضافة مسحوق الكركم بنسبة 0.25% و 0.5 % في عليقة دجاج اللحم قد حسن الاداء الانتاجي وبالتالي يمكن استخدامه كمحفز للنمو.","PeriodicalId":11552,"journal":{"name":"Electronic Journal of University of Aden for Basic and Applied Sciences","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80654481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Dabban, Esam M. G. Al-Badwi, Sarah M. Al-Khadher
{"title":"THEORETICALLY PREDICTED DEVIATION IN PHYSICAL PROPERTIES OF GE-BI-S CHALCOGENIDE ALLOYS WITH COMPOSITIONAL VARIATIONS","authors":"M. Dabban, Esam M. G. Al-Badwi, Sarah M. Al-Khadher","doi":"10.47372/ejua-ba.2023.1.221","DOIUrl":"https://doi.org/10.47372/ejua-ba.2023.1.221","url":null,"abstract":"Chalcogenide glasses (ChGs) semiconductors have several useful properties, especially in their technical applications. The present work explains the compositional dependence of many physical properties of GexBi5S95-x (x = 0, 10, 20, 30, 35 and 45 at. %). Increasing Ge content reduces the fraction of floppy modes, the lone pair electrons, the stoichiometric deviation, and the heat of atomization, while the average coordination number 〈r〉, constraints, density, and molar volume increased, indicating the alloys have moved from floppy to rigid mode. The average overall bond energy, electronegativity difference, band gap energy, and glass transition temperature were estimated by analyzing the bond energies and its distribution based on the bond ordered network model (CONM). It has been found that all these parameters increase with Ge ≤ 30 at. % and decrease with the further increase of Ge content. This behavior can be explained in terms of the network chemical percolation threshold proposed by Tanaka. This threshold represents a topological phase transition from a two-dimensional structure at r˂2.67 to a three-dimensional structure at r≥2.67. The incorporation of Ge into the glassy Bi-S system yields interesting physical properties such as threshold and phase transition, confirming this composition's suitability for optical storage media.","PeriodicalId":11552,"journal":{"name":"Electronic Journal of University of Aden for Basic and Applied Sciences","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83852213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EFFECT OF ALCOHOLIC EXTRACT OF CLOVE (SYZYGIUM AROMATICUM) ON VIABILITY OF PROTOSCOLICES OF SHEEP HYDATID CYSTS IN VITRO","authors":"Hiam Abdull-hameed Saleh Mohammed, A. J. Binsaad","doi":"10.47372/ejua-ba.2023.1.226","DOIUrl":"https://doi.org/10.47372/ejua-ba.2023.1.226","url":null,"abstract":"Clove (Syzygium aromaticum) is one of the most valuable spices that has been used for centuries as food preservative and for many medicinal purposes such as antispasmodic, carminative, antioxidant and antimicrobial. This study was aimed to evaluate the effects of alcoholic extract of clove, on the viability of Echinococcus granulosus protoscolices in vitro. Different concentrations of the clove extract were assessed (1, 50 and 100 mg /ml). The results of the current study showed significant complete inhibition (100%) of protoscolices viability in vitro treated with100 mg/ml of alcoholic extract of S. aromaticum after 3 hours of exposure. Also, 85% inhibition with concentration of 50 mg/ml after 3 hours, progressing to complete inhibition of protoscolices viability after 4 hours. With concentration of 1 mg /ml, 70 % inhibition was observed after 3 hours, progressing to 100% inhibition after 5 hours of exposure to S. aromaticum alcoholic extract. There were significant correlations between efficacy and concentration and between efficacy and exposure time.","PeriodicalId":11552,"journal":{"name":"Electronic Journal of University of Aden for Basic and Applied Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88262264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EVALUATION OF THE LEVELS OF HYDROQUINONE AND HEALTH RISK ASSESSMENT OF TOXIC METALS IN SKIN-WHITENING CREAMS","authors":"T. Osobamiro, Oluwadamilare S. Kukoyi, O. Awolesi","doi":"10.47372/ejua-ba.2023.1.228","DOIUrl":"https://doi.org/10.47372/ejua-ba.2023.1.228","url":null,"abstract":"This study assessed the level of toxic metals and hydroquinone in skin-lightening-creams commonly use in Ogun State, Nigeria. The pH of all the cream samples was determined and metals quantification was carried out using ICP-OES after acid digestion while that of hydroquinone was done using HPLC. The health risk of dermal exposure to heavy metals via the regular application was done by evaluating the carcinogenic and non-carcinogenic risk. The pH of all the samples are acidic and it follows this trend; Sample 3 > Sample 1 > Sample 4 > Sample 2. All the metals considered in this study were detected in all the analyzed samples except Cd, Co and Cr in sample 1, As, Ba and Pb in sample 2, Ag, As and Hg in sample 3 and Ba in sample 4. Highest levels of Al, Co, Pb and Zn were recorded in Sample 3 (Organic cream). Though the concentrations of most of the toxic metals (Al, Zn and Mn) are above the permissible levels, they pose no non-carcinogenic health risk based on the calculated HQ and HI. The carcinogenic risk of metals in the sampled creams were all within the acceptable limit except that of Cd. Hydroquinone was detected in all the four samples analyzed ranging between 2.58 and 4.17 % which exceeded the permissible limit by WHO. This finding show that long-term use of skin-whitening-creams may pose serious health hazards so, public should be continually enlightening on the hazardous health effects of the use.","PeriodicalId":11552,"journal":{"name":"Electronic Journal of University of Aden for Basic and Applied Sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72799536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On Fuzzy Pre-Λ-Sets and Fuzzy Semi-Λ- Sets","authors":"R. M. Aqeel, Anhar Ahmed Nasser","doi":"10.47372/ejua-ba.2023.1.229","DOIUrl":"https://doi.org/10.47372/ejua-ba.2023.1.229","url":null,"abstract":"This paper is devoted to study the notions of fuzzy pre-Λ-set, fuzzy semi-Λ- set, fuzzy pre- V -set and fuzzy semi- V - set in fuzzy topological space. We study some properties and discuss the relationships between fuzzy pre-Λ-set, fuzzy semi-Λ- set, fuzzy pre- V -set and fuzzy semi- V - set and relevant concepts in fuzzy topological spaces and to investigate some basic yet essential properties.","PeriodicalId":11552,"journal":{"name":"Electronic Journal of University of Aden for Basic and Applied Sciences","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91538581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PREVALENCE OF ENTAMOEBA GINGIVALIS IN PATIENTS WITH GINGIVITIS AND PERIODONTITIS AND HEALTHY INDIVIDUALS AND ITS ASSOCIATED FACTORS","authors":"Noor Mohammed Abdulla Afara, A. J. Binsaad","doi":"10.47372/ejua-ba.2023.1.225","DOIUrl":"https://doi.org/10.47372/ejua-ba.2023.1.225","url":null,"abstract":"The present study was carried out to determine the prevalence of Entamoeba gingivalis among 300 (156 males and 144 females) participants divided into three groups as follows: 100 patients with periodontitis (periodontitis group), 100 patients with gingivitis (gingivitis group), and 100 individuals with healthy gingiva (healthy control group), using wet mount technique with physiological saline and Giemsa stain. The overall prevalence of E. gingivalis was 18.3% and the highest prevalence of E. gingivalis was among periodontitis group (29%) followed by gingivitis group (18%), and healthy group (8%). The highest prevalence (23.7%) of E. gingivalis was found among the age group 40-49 years. Infection was highly significant in males than females (23.7% vs.12.5%). With regard to risk factors, the prevalence of E. gingivalis was common in non-tooth brush users, smokers, qat chewers, and diabetic patients and there were significant differences between tooth-brush users and non-tooth brush users, smokers and non-smokers, qat chewers and non-gat chewers, and between diabetic and non-diabetic patients and occurrence of E. gingivalis. We conclude that the higher prevalence of E. gingivalis in periodontal disease compared to healthy individuals may be an indicator of the potential role E. gingivalis in the pathogenesis of periodontal diseases.","PeriodicalId":11552,"journal":{"name":"Electronic Journal of University of Aden for Basic and Applied Sciences","volume":"233 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75514441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"STIPAGROSTIS XYLOSA COPE (TRIBE ARISTIDEAE, ARISTIDOIDEAE, POACEAE) A NEW DISTRIBUTION AND ADDITION TO THE FLORA OF ADEN, YEMEN","authors":"Abeer Ali Saeed, A. Al-Gifri","doi":"10.47372/ejua-ba.2023.1.223","DOIUrl":"https://doi.org/10.47372/ejua-ba.2023.1.223","url":null,"abstract":"During the field trips between September –October 2022 after the good rainfall, have revealed to good collection and one remarkable very rare species Stipagrostis xylosa Cope tribe Aristideae (subfam. Aristidoideae, family Poaceae) is described as a new distribution of species to the flora of Aden. Morphological description and photograph of the species are provided.","PeriodicalId":11552,"journal":{"name":"Electronic Journal of University of Aden for Basic and Applied Sciences","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76219049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}