Egyptian Journal of Medical Research最新文献

{"title":"Correlation between Hyperuricemia and Severity of Coronary Artery Disease Detected by Coronary Angiography in Men and Women","authors":"Mohammed Madbouly, A. Boghdady, Y. Abd el Hady, Khaled R Abd El Meguid","doi":"10.21608/ejmr.2022.263555","DOIUrl":"https://doi.org/10.21608/ejmr.2022.263555","url":null,"abstract":": The association between serum uric acid and ischemic heart disease remains controversial and serum uric acid has not yet been established as cardiovascular risk factor. Our objective was to study the association of serum uric acid level with angiographic severity of coronary artery disease in males and females with ischemic heart disease. This observational study was conducted on two hundred patients divided into one hundred male patient, subdivided into fifty patient with elevated SUA and fifty patient with normal SUA and one hundred female patient subdivided into fifty patient with elevated SUA and fifty patient with normal SUA underwent coronary angiography for detection of CAD in cath lab unit of cardiology department of Beni-Suef and Sohag university. The severity of CAD was assessed on the basis of Gensini score and clinical vessel score. For all groups, conventional risk factors, levels of serum uric acid, and other biochemical markers were assessed.","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80726375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of Diaphragmatic Dysfunction assessed by chest ultrasound on noninvasive ventilation outcome in patients with acute exacerbation of chronic obstructive pulmonary disease.","authors":"N. Laz, Z. Hashim, Waleed R. Arafat","doi":"10.21608/ejmr.2022.263842","DOIUrl":"https://doi.org/10.21608/ejmr.2022.263842","url":null,"abstract":"The Abstract: Background : Noninvasive ventilation (NIV) is now seen as first-line treatment in patients with acute exacerbation of chronic obstructive pulmonary disease and respiratory acidosis (AECOPD). Therefore, the identification of the predictive factors of NIV failure could assist clinicians in detecting the patients at greater risk of negative outcomes. One of these factors is the diaphragmatic dysfunction (DD). Although the measurement of trans-diaphragmatic pressure is the gold current standard for assessing diaphragmatic function, ultrasonography (US) of the diaphragm at the bedside is capable of identifying (DD) in several clinical conditions. Objectives: to evaluate the prevalence of diaphragmatic dysfunction (DD) during AECOPD, and its impact on NIV outcome. Setting: Department of Chest, Respiratory intensive care unit (ICU), Beni-Suef University Hospital. Methods: a prospective observational study which was conducted on 41 adult patients with acute exacerbation of chronic obstructive pulmonary disease who were admitted to respiratory ICU of chest department Beni-Suef University hospital for NIV. The cases underwent diaphragmatic assessment by bedside diaphragmatic ultrasound. Diaphragmatic thickness fraction (DTF) was calculated from the following formula: (Diaphragmatic thickness at end inspiration – Diaphragmatic Thickness at end expiration) / Diaphragmatic Thickness at end expiration. NIV outcomes (failure and success groups) was analyzed to find a cutoff point of DTF to predict success of NIV. Results: The prevalence of diaphragmatic dysfunction in all studied patients was 18 patients (43.5%) out of 41 patients most of them were among NIV failure group [12 (70.5%) out of 17 patients]. The cut off point of DTF was below 0.306 to predict failure of NIV . with a P value 0.002. Conclusions : Assessment of DTF by diaphragm ultrasound in B-mode represents an easy to-obtain new index for prediction of success or failure of NIV in AECOPD patients needing NIV.","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":"346 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84856180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survey of non-alcoholic steatohepatitis in non-diabetic Haemodialysis patients in Beni-Suef Governorate","authors":"Ahmed Ibrahima, M. Salem, M. Abdel-Rahman, Tamer Mohamed","doi":"10.21608/ejmr.2022.271021","DOIUrl":"https://doi.org/10.21608/ejmr.2022.271021","url":null,"abstract":": Background : Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are global health issues all over the world, affecting about30% (NAFLD), and15% (CKD) of general people. Even, with absence of other risk factors such as overweight, diabetes and hypertension, there is force correlation between NAFLD and CKD. Objective: The target of our study is to detect the incidence of non-alcoholic steatohepatitis between non-diabetic hemodialysis patients by measuring Controlled Attenuation Parameter (CAP) using transient elastography (TE) (Fibroscan®). Methodology: This was a cross sectional study in Beni-Suef governorate, including 1000 hemodialysis non-diabetic ESRD patients from different hemodialysis units from all the central hospitals in Beni-Suef governorate. Results : According to CAP (dB/M) there were 503(50.3%) S0, 233(23.3%) S1, 100(10.0%) S1-S2, 67(6.7%) S2,10(1.0%) S2-S3 and 87(8.7%) S3. According to liver stiffness grades there were 508(50.8%) F0, 280(28.0%) F1, 57(5.7%) F2,95(9.5%) F3 and 60(6.0%) F4. There were 508(50.8%) F0 and 492(49.2%) F1:F4 with mean 6.14 (± 3.90SD) and range (2.0 – 19.90). Conclusions: In this study we concluded that there is a high incidence of NAFLD among non-diabetic patients on regular Hemodialysis in Beni-Suef governorate, significantly correlated with increasing degree of liver stiffness.","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83671439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Ranibizumab alone versus Ranibizumab with Targeted Retinal Laser for Branch Retinal Vein Occlusion with Macular Oedema.","authors":"Mohamed Abdelmoneem, Mohamed Sayed Saif, Mohamed Abd Elkalek","doi":"10.21608/ejmr.2021.98694.1142","DOIUrl":"https://doi.org/10.21608/ejmr.2021.98694.1142","url":null,"abstract":": Background: Retinal vein occlusion is the second most common retinal vascular disease after diabetic retinopathy. Branch retinal venous occlusion (BRVO) occurs the occlusion of one of the branches of the retinal vein. The occlusion occurs mostly at arteriovenous crossing and more frequent in upper temporal retinal veins. Patients and Methods: In the current study, randomized control study was conducted on 2 groups divided into 27 eyes (Ranibizumab alone), 27 eyes (Ranibizumab and Targeted retinal laser). Results: The BRVO is investigated by FFA and OCT-Macula and macular edema is measured by OCT-Macula. And the current result shows highly statistically significant improvement in visual acuity and reducing macular edema (decrease foveal thickness)with P value <0.001 in Ranibizumab alone compared with Ranibizumab and retinal laser.","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84296928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of three chip high definition camera with modular enhancement system with white light cystoscopy during transurethral resection of bladder tumours. Does it improve carcinoma in situ detection?","authors":"A. Abdelbary, Ossama Mohamad, A. Abd El Latif, Almotasem Bellah Adel, Akram A. Elmarakbi","doi":"10.21608/ejmr.2022.266078","DOIUrl":"https://doi.org/10.21608/ejmr.2022.266078","url":null,"abstract":": The goal of our study is to assess if the use of Storz professional image enhancement system (SPIES) improve carcinoma in situ (CIS) detection. We conducted a prospective study on 35 patients of both sexes who have fulfilled the inclusion criteria from December 2019 to May 2020. Preoperatively, we collected urine samples from all patients amenable for cystoscopy for urine analysis and urine cytology. Contrast enhanced abdomen and pelvic computerized tomography (CT) was done for all patients. Under spinal anaesthesia white light cystoscopy (WLC) was done first, then SPIES camera was used by the same operator to detect any other suspicious lesions. TURBT was done for all lesions and specimens were sent for histopathology assessment. Our results showed that there was statistically significant difference between the SPIES and WLC regarding the number of lesions detected, as the total number of lesions detected by the SPIES was 37 lesions, three of these lesions were CIS, but the WLC detected only 27 lesions, no CIS was detected by WLC ( p value 0.001). Pathological recurrence was confirmed in 6/35 (17.1%) patients at 3 months follow up.","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91134830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circular Ribonucleic Acid Expression in Patient with Acne","authors":"A. El-Taweel, Abd-Elaziz Al-Refae, Mona Abd-Ellateef, R. Mohammad","doi":"10.21608/ejmr.2021.88645.1101","DOIUrl":"https://doi.org/10.21608/ejmr.2021.88645.1101","url":null,"abstract":": Background: Acne is a common chronic skin disease with a multifactorial aetiology and pathogenesis. Recently, circular RNAs (circRNAs) have been identified as a key factor in regulating gene expression through circRNA–miRNA–mRNA networks in many biological processes and human diseases. However, the circRNAs expression in patients with acne is still unknown, Aim and Objectives: To evaluate circular RNA Expression in Patient with Acne and to correlate its level with acne severity, Subjects and Methods: this was a case control study was conducted at conducted at Dermatology outpatient clinic at Beni-Suef University hospital including 40 with acne vulgaris and 40 normal as control. The duration of the study ranged from 6 months, Results: The mean CIRCULAR RNA 0001073 for cases group was 0.47 (±0.3 SD) with range (0.11-1.2) and that the mean CIRCULAR RNA 0001073 for control group was 1.03 (±0.1 SD) with range (0.95-1.2), and There was high statistically significant difference between the studied groups as regard CIRCULAR RNA 0001073. Conclusion: This study firstly showed that circRNAs were differentially expressed in severe acne and suggested that circRNAs could be used as a potential biomarker for the drug targets of acne.","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90877973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relation between Vitamin D Receptors Gene Polymorphism and Lupus Nephritis","authors":"Heba Mahmoud, Mahmoud B. Ahmed, Shaimaa Abd elkareem, Hanaa Rabie","doi":"10.21608/ejmr.2022.256658","DOIUrl":"https://doi.org/10.21608/ejmr.2022.256658","url":null,"abstract":": The goal of this study is to Correlate between Vitamin D receptor polymorphism (FOKI) and lupus nephritis. Eighty subjects were included in this study. They were divided into two groups as follows: Control group: consisted of twenty apparently healthy volunteers of comparable age and socioeconomic status to the patients group. Patients group: consisted of sixty patients with SLE. They were selected from the Internal Medicine departement and Rheumatology out patient clinic of Beni-suef University hospital. In this study, Regarding CBC changes ,The prevalence of thrombocytopenia and lymphopenia was significantly higher among SLE patients compared to our controls, However the prevalence of lymphopenia and leucopenia was significantly higher among SLE patients with GG genotype compared to SLE patients with AG and AA mutants ,Regarding liver function tests, The mean serum Albumin level was significantly lower among SLE patients compared to controls .Antinuclear antibody titre was significantly higher among SLE patients than controls ,Also Anti Ds DNA is represented in SLE patients in ahigh titre than healthy controls ,Furthermore, All SLE patients with GG genotypes had positive Anti Ds DNA( 100%) compared to SLE patients with AG ( 0,0) and AA ( 0,0) mutants. It is recommended to carry out further studies on FOKI gene polymorphisms in larger groups of patients and controls.","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81462889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of IL18 serum levels in COVID-19 Patients at Beni- Suef University Hospital","authors":"Nada El-Sagheer, A. Gomaa, Laila A Alsharaway, M. Abdel-Aziz","doi":"10.21608/ejmr.2022.259009","DOIUrl":"https://doi.org/10.21608/ejmr.2022.259009","url":null,"abstract":"","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76373397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Depression and Its Relation to Mental Health Problems in children","authors":"Asmaa Awad, Maha Ahmed, H. Zaki, M. Salem","doi":"10.21608/ejmr.2022.251449","DOIUrl":"https://doi.org/10.21608/ejmr.2022.251449","url":null,"abstract":": This work aimed at determining the relation between maternal depression and emotional & behavioral problems in children aged 1 ½ to 5 y in the Egyptian pediatric population. This exploratory cross-sectional study was conducted at the pediatric outpatient clinic, at Beni- Suef University Hospital, over a period twenty months from September 2016 to May 2018. The total number of participants who were at the first visit was 164 participants, they completed all the questionnaires, but 20 participants didn’t attend the next visit after two weeks from the first visit, so the total number that participated in the two visits was 143 participants .The current study reported that self-report screening for maternal depression is feasible in primary care settings. In our study the results showed that a large numbers of mothers have depression about 87.8 % of the participant mothers have depression in the first and the second interview. In conclusion, the current study revealed that maternal depression was significantly related to higher levels of internalizing, externalizing, and general psychopathology.","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87944409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of hypocalcemia in asymptomatic pregnant females in Upper Egypt","authors":"Asmaa Mohamed Abdel- Aty, M. Youssef, Y. Mohamed","doi":"10.21608/ejmr.2022.251656","DOIUrl":"https://doi.org/10.21608/ejmr.2022.251656","url":null,"abstract":": The goal of this study is to investigate the levels of serum calcium in asymptomatic pregnant women and measuring the prevalence of hypocalcaemia. Healthy pregnant women (n=500) were enrolled consecutively, with singleton pregnancy, in first trimester with the mean gestational age (9.5 ±1) weeks of gestation. Serum Total and Ionized calcium were measured to all women in the study. The prevalence of hypocalcaemia was measured. Nearly two thirds of women (337) had hypocalcaemia (67.4%), Only 163 had normal calcium levels\" serum calcium level of 8.6 mg/dL or above\". The prevalence of hypocalcaemia was more in young aged women as about two-thirds (64.8%) were in the age group 20 to less than 30 years, with mean age 23.9 ±4.6 years. Also the prevalence of hypocalcaemia was high in parity less than 2, with statistically significant p-value (0.034). No determinants (education, dietary intake of Ca +2 , weight, height, BMI, and Hb levels) found in our study to be in correlation with the high incidence of hypocalcaemia.","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72801771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}