hanaa salah ebrahim, Seham S. El‐Hawary, Gihan Fouad Ahmed, Essam Mostafa Abd El-Kader, Marwa Y. Issa
{"title":"Dillenia species: Insight into Managing Neurodegenerative Diseases","authors":"hanaa salah ebrahim, Seham S. El‐Hawary, Gihan Fouad Ahmed, Essam Mostafa Abd El-Kader, Marwa Y. Issa","doi":"10.21608/ejchem.2025.322266.10487","DOIUrl":"https://doi.org/10.21608/ejchem.2025.322266.10487","url":null,"abstract":"For thousands of years, various species of Dillenia have been used as a common herbal remedy in traditional medicine. Dillenia has been prized for its therapeutic properties, including microbial infections, gastrointestinal disorders, fever, headaches, diabetes, tumors, and cardiovascular issues. The genus is also known for its neuroprotective, anti-cholinesterase, antioxidant, and anti-inflammatory effects. The present review aims to compile the available evidence on the medicinal plants of the Dillenia genus specifically D. bracteata Wight, D. indica L., D. pentagyna Roxb., and D. suffruticosa Griffith Ex. Hook. F. & Thomsom Martelli, with a focus on their phytochemical properties in treating and preventing neurodegenerative disorders. Literature indicates Dillenia significant role in herbal therapy, with many phytoconstituents, primarily terpenoids and flavonoids. Recent pharmacological studies suggest its crucial role in traditional medicine and promising potential through its antioxidant, anti-inflammatory, and neuroprotective properties. This review highlights Dillenia pharmacological effects on neurodegenerative diseases. According to the literature, the active terpenoids and flavonoids in Dillenia are primarily responsible for its therapeutic actions. Comprehensive research on the genus's pharmacokinetics, metabolism, medication interactions, and mechanisms of action, however, is lacking. Therefore, extensive research and evaluation are needed to fully understand the potential of Dillenia in modern medicine.","PeriodicalId":11498,"journal":{"name":"Egyptian Journal of Chemistry","volume":"0 0","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ejchem.journals.ekb.eg/article_409740_d73f622ec33a0f2f87c0500c7c6c7950.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147891352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marwa Y. Issa, hanaa salah ebrahim, Seham S. El‐Hawary, Gihan Fouad Ahmed, Essam Mostafa Abd El-Kader
{"title":"Dillenia indica L. Fruits Cultivated in Egypt: Nutritional Features.","authors":"Marwa Y. Issa, hanaa salah ebrahim, Seham S. El‐Hawary, Gihan Fouad Ahmed, Essam Mostafa Abd El-Kader","doi":"10.21608/ejchem.2024.315326.10264","DOIUrl":"https://doi.org/10.21608/ejchem.2024.315326.10264","url":null,"abstract":"South Asia is the home to many tropical trees, most famously the elephant apple (Dillenia indica L.). Mostly found in Assam, in the northeast of India and not grown for commercial purposes, elephant apples are used in many different culinary recipes in their native country. The current study aims to characterize the nutritional and biochemical properties of the fruit constituents. The ethanol extract physicochemical properties and phytochemical screening study were presented. The fruit is proved to have considerable concentrations of flavonoids and phenolics. The fruit fatty matter analysis exposed that carbohydrates were more than 50%. Additionally, lupeol and betulin were the main terpenoids. Arachidic acid was the dominant fatty acid. Advanced nutritive value detection demonstrated the presence of minerals and vitamins, while potassium (11667 mg/kg) and vitamin A (1.30 µg/g) were the leading. Furthermore, apigenin (661.6 µg/g) and ellagic acid (1064.71µg/g) were the highest flavonoids and phenolics. The study revealed glycine (3780.77 µg/g) as the prominent amino acid for the first time, in addition to eight essential amino acids. The fruits offer special nutritional significance. Beyond its dietary value, D. indica fruit has been associated with other health benefits.","PeriodicalId":11498,"journal":{"name":"Egyptian Journal of Chemistry","volume":"0 0","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147910469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara A. M. El‐Sayed, Mostafa Mabrouk, Ahmed R. Wassel, Mahmoud T. Abo‐Elfadl, boyhaina Abdelhady, Hanan H. Beherei
{"title":"Indomethacin Delivery from PCL Nanofibrous Scaffolds Enhances Biomineralization and Cell Adhesion: Biocompatible Scaffold Model for Teeth Regeneration","authors":"Sara A. M. El‐Sayed, Mostafa Mabrouk, Ahmed R. Wassel, Mahmoud T. Abo‐Elfadl, boyhaina Abdelhady, Hanan H. Beherei","doi":"10.21608/ejchem.2024.306910.10076","DOIUrl":"https://doi.org/10.21608/ejchem.2024.306910.10076","url":null,"abstract":"3D porous scaffolds have shown remarkable promise in the fields of tissue regeneration and medication delivery. This study focuses on constructing uniform 3D structures from polycaprolactone (PCL) loaded with nano-bioactive glass (58S) for the purpose of facilitating the development of dental cells. The scaffold surfaces were activated using chitosan, a biocompatible compound. The scaffolds underwent thorough characterization, encompassing the assessment of their physicochemical properties, thermal behavior, and microstructural aspects. A study was conducted on the release of the anti-inflammatory drug indomethacin, and the mode of cell death was evaluated using MG-63 cell lines. Human Dental Pulp Stem Cells (HDPSCs) were specifically planted into the scaffolds made of nanofibers. Scanning electron microscopy (SEM) investigation demonstrated significant cell adhesion, multiplication, and expansion. The scaffolds containing 58S exhibited markedly larger densities of mineralized nodules produced by HDPSCs, suggesting enhanced mineralization and the possibility of enhanced regeneration of tooth tissue. The results revealed that the scaffolds contained 58S (NF6) and the scaffolds that contained the drug into the nanofibers matrix (NF7) had a slower release rate (9%) than the scaffolds that contained the drug through the coated layer (NF4) which was 16%. Moreover, the cell viability illustrated that (NF4), (NF6) and (NF7) are the best samples which recorded more than 300%, 100% and 200% viability percent, respectively. These novel 3D homogenous scaffolds show significant potential for precise drug administration and the restoration of dental tissues, leading to revolutionary progress in dental healthcare.","PeriodicalId":11498,"journal":{"name":"Egyptian Journal of Chemistry","volume":"0 0","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ejchem.journals.ekb.eg/article_375885_ffad001a6b6240e2001daa7278b13a9a.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147906410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sameh Sobhy El‐Hadad, Natali Tikhomirova, Hamdy Zahran, Mahmoud Abd El-Aziz, Rehab S. Sayed
{"title":"The Effect of Minor Components of Wheat Germ Oil on Thermal Behavior, Crystallization Characteristics, and Oxidative Stability of Butter Oil","authors":"Sameh Sobhy El‐Hadad, Natali Tikhomirova, Hamdy Zahran, Mahmoud Abd El-Aziz, Rehab S. Sayed","doi":"10.21608/ejchem.2024.244642.8776","DOIUrl":"https://doi.org/10.21608/ejchem.2024.244642.8776","url":null,"abstract":"","PeriodicalId":11498,"journal":{"name":"Egyptian Journal of Chemistry","volume":"4 18","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139457786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mayada A. El-Hiny, Marwa El Shamarka, Nermeen M. Shaffie, Omar Abdel-Salam
{"title":"Modulation Of The Neurochemical And Behavioral Changes Induced By Nandrolone Decanoate And Nicotine Combination In Rats Using Grape Seed Extract","authors":"Mayada A. El-Hiny, Marwa El Shamarka, Nermeen M. Shaffie, Omar Abdel-Salam","doi":"10.21608/ejchem.2024.248569.8875","DOIUrl":"https://doi.org/10.21608/ejchem.2024.248569.8875","url":null,"abstract":"","PeriodicalId":11498,"journal":{"name":"Egyptian Journal of Chemistry","volume":"83 7","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139454628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atef T. El Masry, Dalia E. El-Hefny, Rania, M.A. Helmy, Ahmed A.A. El-Ghanam
{"title":"Effect of some insecticides, depletion and risk assessment against whitefly stages, Bemisia tabaci (Gennadius) on cucumber cultivation","authors":"Atef T. El Masry, Dalia E. El-Hefny, Rania, M.A. Helmy, Ahmed A.A. El-Ghanam","doi":"10.21608/ejchem.2024.231222.8478","DOIUrl":"https://doi.org/10.21608/ejchem.2024.231222.8478","url":null,"abstract":"","PeriodicalId":11498,"journal":{"name":"Egyptian Journal of Chemistry","volume":"116 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139453820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Abbas, Ahmed Adawy, Amr Ismail, Ibrahim Nassar
{"title":"Non-ionic Polymeric Surfactants of Fatty-Polyethylene Glycol-L-Cysteine as Acid Corrosion Inhibitor","authors":"Mohamed Abbas, Ahmed Adawy, Amr Ismail, Ibrahim Nassar","doi":"10.21608/ejchem.2024.244108.8761","DOIUrl":"https://doi.org/10.21608/ejchem.2024.244108.8761","url":null,"abstract":"","PeriodicalId":11498,"journal":{"name":"Egyptian Journal of Chemistry","volume":"63 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139454998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asmaa Mourad, Fatehia Mohammed, Gamal Tammam, Ahmed A F Soliman, S. Mohammed
{"title":"Elaboration and Evaluation of Diverse Fused Pyrano[2,3-d]pyrimidinones: Synthesis, Characterization, and Antimicrobial Efficacy Assessment","authors":"Asmaa Mourad, Fatehia Mohammed, Gamal Tammam, Ahmed A F Soliman, S. Mohammed","doi":"10.21608/ejchem.2023.245247.8808","DOIUrl":"https://doi.org/10.21608/ejchem.2023.245247.8808","url":null,"abstract":"","PeriodicalId":11498,"journal":{"name":"Egyptian Journal of Chemistry","volume":"55 14","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}