Egyptian Journal of Anaesthesia最新文献_第10页

Endothelial glycocalyx shedding during active COVID-19 infection and its effect on disease severity COVID-19活动性感染期间内皮糖萼脱落及其对疾病严重程度的影响

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Egyptian Journal of Anaesthesia Pub Date : 2023-03-27 DOI: 10.1080/11101849.2023.2192099

A. Hieba, Emad Abdelmoenam Arida, H. Osman, S. Imbaby, Heba A. Moharem

{"title":"Endothelial glycocalyx shedding during active COVID-19 infection and its effect on disease severity","authors":"A. Hieba, Emad Abdelmoenam Arida, H. Osman, S. Imbaby, Heba A. Moharem","doi":"10.1080/11101849.2023.2192099","DOIUrl":"https://doi.org/10.1080/11101849.2023.2192099","url":null,"abstract":"ABSTRACT Background COVID-19 pandemic was caused by the SARS-CoV-2 virus that was thought to be associated with microvascular endothelial injury. This study aimed to demonstrate the effect of COVID-19 on markers of endothelial shedding and its effect on patient morbidity and mortality. Settings and design This was a prospective cohort study. Methods This study was conducted at the isolation hospital at Alexandria Main University hospitals on 40 adult patients infected with COVID-19. Patients were divided according to the severity of the presenting symptoms into two groups; moderate and severe. Serum levels of Syndecan-1 and Heparan sulfate were measured at hospital admission and at the end of the first week. Clinical and demographic data along with laboratory investigations and outcomes were compared between the two groups. Results Our results indicated that patients with severe symptoms of COVID-19 had notably high levels of syndecan-1 and Heparan sulfate compared to patients with moderate symptoms on day 1 and day 7. Further investigations revealed that D-dimer, CRP, and IL-6 levels in patients with severe symptoms were higher in patients with severe symptoms. Our results also indicated that IL-6 increased on day 4 and gradually decreased on day 7 in both groups. Furthermore, serum levels of Syndecan-1, Heparan sulfate, D-dimer, and CRP decreased gradually from day 1 to day 7 in both groups. There was an association between markers of endothelial shedding with thrombotic and cardiovascular complications. It seems that the serum Syndecan-1 and Heparan sulfate might be good candidates to monitor COVID-19 activity. Conclusion Patients with severe symptoms of COVID-19 have high serum levels of syndecan 1 compared to patients with moderate symptoms and have higher mortality and more prolonged hospital stay due to more endothelial injury and inflammatory reaction. Syndecan-1 may be used to monitor disease progression and severity.","PeriodicalId":11437,"journal":{"name":"Egyptian Journal of Anaesthesia","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42725779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced recovery after spinal surgery protocol versus conventional care in non- insulin diabetic patients: A prospective randomized trial 非胰岛素型糖尿病患者脊柱手术方案与常规治疗相比恢复率提高：一项前瞻性随机试验

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Egyptian Journal of Anaesthesia Pub Date : 2023-03-27 DOI: 10.1080/11101849.2023.2196113

Sarah Mohamed Elgamal, A. Abdelhalim, Emad Abdelmoneim Arida, Abdulrahman Magdy Elhabashy, R. Sabra

{"title":"Enhanced recovery after spinal surgery protocol versus conventional care in non- insulin diabetic patients: A prospective randomized trial","authors":"Sarah Mohamed Elgamal, A. Abdelhalim, Emad Abdelmoneim Arida, Abdulrahman Magdy Elhabashy, R. Sabra","doi":"10.1080/11101849.2023.2196113","DOIUrl":"https://doi.org/10.1080/11101849.2023.2196113","url":null,"abstract":"ABSTRACT Background Enhanced Recovery After Surgery (ERAS) approach was proven in many surgical specialties. This prospective, randomized, single-blinded trial was designed to assess the effectiveness of ERAS on quality of recovery (QOR) after surgery in non-insulin-dependent diabetic patients. Patients and methods 72 patients undergoing elective lumbar decompressive surgery were randomly allocated to one of two equal groups receiving either ERAS protocol in group E or conventional care in group C. QOR after surgery using QOR-40 score, pain score, perioperative opioid consumption, time to early ambulation, serum markers of stress response, length of stay and possible perioperative complications were recorded. Results QOR-40 scores were significantly greater in group E at PACU, first postoperative day and second postoperative day (P = 0.015, 0.041 and 0.048, respectively). VAS was significantly lower in group E in the first eight hours postoperative. Time to first postoperative analgesic requirement was significantly longer in group E (P = 0.0001). Intraoperative fentanyl and postoperative nalbuphine requirements were significantly less in group E (P = 0.001, and 0.0001, respectively). Time to early ambulation was significantly less in group E (P = 0.006). Both CRP and interleukin-6 were significantly less at the second postoperative day in group E (P = 0.001, and 0.017, respectively). There was insignificant difference among groups in length of hospital stay and intraoperative insulin requirements (P = 0.251, and 0.347, respectively). Conclusion In non-insulin diabetic patients, enhanced recovery after spinal surgery improved quality of recovery, lowered pain scores, reduced perioperative opioid consumption, allowed early ambulation and decreased stress response but not length of hospital stay.","PeriodicalId":11437,"journal":{"name":"Egyptian Journal of Anaesthesia","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47431138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Special maternal care bundle to attenuate post-spinal hypotension in cesarean section: A randomized controlled clinical trial 特殊产妇护理包减轻剖宫产术后脊髓性低血压的随机对照临床试验

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Egyptian Journal of Anaesthesia Pub Date : 2023-03-23 DOI: 10.1080/11101849.2023.2194094

A. Alshawadfy, Shaimaa A Dahshan, Ahmed A. Ellilly, Ahmed M. Elewa

{"title":"Special maternal care bundle to attenuate post-spinal hypotension in cesarean section: A randomized controlled clinical trial","authors":"A. Alshawadfy, Shaimaa A Dahshan, Ahmed A. Ellilly, Ahmed M. Elewa","doi":"10.1080/11101849.2023.2194094","DOIUrl":"https://doi.org/10.1080/11101849.2023.2194094","url":null,"abstract":"ABSTRACT Background This study aimed to assess the safety and efficacy of a special maternal care bundle as an alternative technique for the attenuation of hypotension following spinal anesthesia in parturients scheduled for CS. Methods This double-blinded, parallel-group, randomized trial enrolled 138 adult parturients who were scheduled for CS under spinal anesthesia. The patients were randomly allocated to two groups. In the care bundle group, 68 participants received a co-load of lactated Ringer’s solution and ondansetron infusion during administration of spinal anesthesia with a slow rate intrathecal bupivacaine injection and a V-shaped supine position. While in the best practice group, 70 participants received a co-loaded lactated Ringer’s solution during spinal anesthesia with early use of vasopressors and a left uterine tilting position. The primary outcome was the total ephedrine consumption. Secondary outcomes included the mean arterial blood pressure, heart rate, atropine usage, complications such as dizziness, nausea, and vomiting, as well as the baby’s Apgar score. Results Special maternal care bundle significantly reduced the need and the total dose of ephedrine (P = 0.042). The mean arterial blood pressure was significantly less affected by maternal bundle care, but the reduction in heart rate, the need for atropine, the incidence of dizziness, nausea, vomiting, and the Apgar score were comparable in both groups. Conclusion The special maternal care bundle including co-load of lactated ringer, ondansetron 4 mg IV infusion, slow intrathecal injection and v-shaped positions can reduce the incidence of hypotension resulting from spinal anesthesia and ephedrine usage during CS.","PeriodicalId":11437,"journal":{"name":"Egyptian Journal of Anaesthesia","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44621341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of musculoskeletal disorders in anesthesiologists in Ismailia Governorate 伊斯梅利亚省麻醉师中肌肉骨骼疾病的患病率

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Egyptian Journal of Anaesthesia Pub Date : 2023-03-23 DOI: 10.1080/11101849.2023.2193016

Eslam Albayadi, Abelrahman Soliman, Wesam F. Alyeddin

{"title":"Prevalence of musculoskeletal disorders in anesthesiologists in Ismailia Governorate","authors":"Eslam Albayadi, Abelrahman Soliman, Wesam F. Alyeddin","doi":"10.1080/11101849.2023.2193016","DOIUrl":"https://doi.org/10.1080/11101849.2023.2193016","url":null,"abstract":"ABSTRACT Aim Detect the prevalence of work-related musculoskeletal disorders among anesthesiologists and their related risk factors. Methods This cross-sectional study was conducted on anesthesia and intensive care physicians in Ismailia/Egypt from June to July 2022. The questionnaire had three parts. The first part consisted of participants’ demographic data. The second focused on musculoskeletal disorders and possible risk factors. The last one questioned the impact of musculoskeletal disorders on the participants. Results The mean age of the studied population was 35.65 ± 7.734. Thirty-eight (41.8%) participants worked for 60–80 hours/week. The whole study participants reported the presence of at least one form of MSDs. Back pain was the most reported pain (78%), followed by neck pain (50.5%). Possible risk factors included the need for excessive bending and twisting, poor work ergonomics that needs improvement as reported by (81.3%) of participants and suboptimizing patient’s position before specific procedures by two thirds of the participants. The physicians reported difficulty falling asleep, feeling anxious, and needing medication to control pain; however, they did not require sick leave (79.1%). Conclusion A significant proportion of anesthetists suffer from WRMSDs. Work ergonomics need improvement.","PeriodicalId":11437,"journal":{"name":"Egyptian Journal of Anaesthesia","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49220325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of percutaneous adhesiolysis for the management of chronic pain due to post spine surgery syndrome 经皮粘连松解术治疗脊柱手术后综合征引起的慢性疼痛的评价

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Egyptian Journal of Anaesthesia Pub Date : 2023-03-21 DOI: 10.1080/11101849.2023.2189238

S. Asida, S. Elsawy, Mahmoud Faisal, Ossama Hamdy

{"title":"Evaluation of percutaneous adhesiolysis for the management of chronic pain due to post spine surgery syndrome","authors":"S. Asida, S. Elsawy, Mahmoud Faisal, Ossama Hamdy","doi":"10.1080/11101849.2023.2189238","DOIUrl":"https://doi.org/10.1080/11101849.2023.2189238","url":null,"abstract":"ABSTRACT Background Failed back surgery syndrome (FBSS) is a persistent radicular and/or lumbar pain following spine surgery. Percutaneous adhesiolysis (PA) has proved efficacy for the treatment of intractable chronic pain after failure of conservative management. Aim Our research aims to investigate the effectiveness and safety of percutaneous epidural adhesiolysis using RACZ catheter as Numeric rating scale during 6-month duration as a primary outcome and catheter related complication as a secondary outcome among patients suffering chronic leg and low back pain in patients with failed back surgery syndrome. Methods 20 patients who were screened diagnosed as FBSS determined by MRI and patient symptoms during enrollment phase completed the study by passing Racz epidural catheter through Racz needle to the region of the filling defect. Results High statistically significant difference was found in NRS scores versus time in the study group when analyzed by Friedman test (P < 0.001) with 40%, 50%, 58% and 56% improvement in NRS at 2 weeks, 1 month, 3 months and 6 months, respectively. Conclusion Racz adhesiolysis is effective in improving pain scores in patients with FBSS after failure of conservative medical therapy.","PeriodicalId":11437,"journal":{"name":"Egyptian Journal of Anaesthesia","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43156976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

General anesthesia and femoral nerve block versus spinal anesthesia for cemented hip arthroplasty in elderly patients: A randomized controlled trial 老年患者骨水泥髋关节置换术的全身麻醉和股神经阻滞对比:一项随机对照试验

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Egyptian Journal of Anaesthesia Pub Date : 2023-03-21 DOI: 10.1080/11101849.2023.2189267

T. Abdelrahman, Nahla Omar Salama, G. Zaki, Heba Bahaa El Din El Serwi, A. Moussa

{"title":"General anesthesia and femoral nerve block versus spinal anesthesia for cemented hip arthroplasty in elderly patients: A randomized controlled trial","authors":"T. Abdelrahman, Nahla Omar Salama, G. Zaki, Heba Bahaa El Din El Serwi, A. Moussa","doi":"10.1080/11101849.2023.2189267","DOIUrl":"https://doi.org/10.1080/11101849.2023.2189267","url":null,"abstract":"ABSTRACT BACKGROUND Traumatic femoral fractures are a prevalent orthopaedic issue in elderly adults. General anaesthesia (GA) vs. spinal anaesthesia are still being discussed as the best anaesthetic method for cemented hip arthroplasty (SA). This study compared the impact of spinal anaesthesia versus general anaesthesia in combination with femoral nerve block on the mean arterial blood pressure (MAP) in patients having cemented hip arthroplasty operations. AIM OF THE STUDY To compare the impact of spinal anaesthesia on elderly patients undergoing cemented hip arthroplasty operations versus general anaesthesia in combination with femoral nerve block on mean arterial blood pressure. PATIENTS AND METHODS The study was registered at Pan African-Clinical Trial Registry.org with ID of (PACTR 202,111,575,647,784). At Ain Shams University Hospital, 60 patients receiving total hip arthroplasty were separated into two equal groups, each comprising 30 patients, for the purpose of this prospective randomised comparison study. Patients in Group (A) underwent spinal anaesthesia, while Group (B) received general anaesthesia together with an ultrasound-guided femoral nerve block. RESULTS This study showed that GA was associated with more stable readings of mean arterial blood pressure (MAP) after anesthesia induction and post cement implantation than SA (p-value = 0.04 and 0.038 respectively). CONCLUSION Patients who received general anesthesia (GA) had more stable hemodynamic parameters especially the mean arterial blood pressure (MAP) than those who received spinal anesthesia (SA).","PeriodicalId":11437,"journal":{"name":"Egyptian Journal of Anaesthesia","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48508760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison between combined regional nasal block and general anesthesia versus general anesthesia with dexmedetomidine during endoscopic sinus surgery 内窥镜鼻窦手术中区域鼻阻滞与全麻及右美托咪定全麻的比较

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Egyptian Journal of Anaesthesia Pub Date : 2023-03-21 DOI: 10.1080/11101849.2023.2192097

Moustafa Atef Moustafa Hamouda, Nahed E. Salama, Samia A. Hassan, E. Aboseif, R. A. Abdelrazik

{"title":"Comparison between combined regional nasal block and general anesthesia versus general anesthesia with dexmedetomidine during endoscopic sinus surgery","authors":"Moustafa Atef Moustafa Hamouda, Nahed E. Salama, Samia A. Hassan, E. Aboseif, R. A. Abdelrazik","doi":"10.1080/11101849.2023.2192097","DOIUrl":"https://doi.org/10.1080/11101849.2023.2192097","url":null,"abstract":"ABSTRACT Background Research findings are inconsistent regarding the efficiency of regional nasal blocks over hypotensive techniques. The current study aimed to compare regional nasal block to dexmedetomidine (DEX) for surgical field optimization. Methods A total of 70 patients (ASA I or II) aged 18 to 65 years were divided into two groups (35 patients each). The DEX group received 1 µg/kg of DEX in 10 minutes after induction of anesthesia, followed by 0.7 µg/kg/hour during maintenance of anesthesia. The other group [Sphenopalatine ganglion block (SPGB) group] was subjected to regional nasal block by SPGB immediately after induction of general anesthesia. This was done via a transoral approach using 2 ml of a mixture of lidocaine (2%) and bupivacaine (0.5%) for each side. Results Surgical conditions were satisfactory in all patients of both groups, but significantly better with bilateral SPGB. In addition, the block group had also improved extubation characteristics and postoperative analgesia. Patients who received bilateral SPGB complained significantly of dental numbness. Conclusions Both DEX and regional nasal block provided excellent functional endoscopic sinus surgery (FESS) with a high score of surgeons’ satisfaction. The SPGB can provide better surgical field optimization with less blood loss, less intraoperative analgesic consumption, and early extubation with minor complications, and better immediate postoperative pain profile. So, SPGB can be used efficiently and safely in combination with general anesthesia in patients undergoing FESS.","PeriodicalId":11437,"journal":{"name":"Egyptian Journal of Anaesthesia","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41840548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lung ultrasound compared to fiber-optic bronchoscopy in detecting proper endotracheal tube position in intubated patients in the intensive care unit 肺超声与纤维支气管镜在重症监护病房插管患者气管插管位置检测中的比较

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Egyptian Journal of Anaesthesia Pub Date : 2023-03-21 DOI: 10.1080/11101849.2023.2190692

Omar Sayed Osman Abdeen, Raouf Ramzy Gad Allah, T. Shabana, T. A. Nasr, Waleed Abdalla Ibrahem

{"title":"Lung ultrasound compared to fiber-optic bronchoscopy in detecting proper endotracheal tube position in intubated patients in the intensive care unit","authors":"Omar Sayed Osman Abdeen, Raouf Ramzy Gad Allah, T. Shabana, T. A. Nasr, Waleed Abdalla Ibrahem","doi":"10.1080/11101849.2023.2190692","DOIUrl":"https://doi.org/10.1080/11101849.2023.2190692","url":null,"abstract":"ABSTRACT Background Accidental endobronchial intubation can lead to serious complications in critically ill patients, which can be avoided through early detection and proper positioning of the endotracheal tube. This cross-sectional study estimates lung ultrasound’s sensitivity in detecting the proper position of the endotracheal tube compared to auscultation and fiberoptic bronchoscopy. Methods Sixty intubated adult ICU patients were examined by auscultation, ultrasound, and fiberoptic bronchoscope by three different blinded physicians to detect the position of the ETT (endotracheal, right, and left endobronchial). An ultrasound examination was done by evaluating the lung sliding sign. Statistical analysis included sensitivity, specificity, PPV, and NPV. Results Auscultation showed 64% sensitivity, 100% specificity, 100% positive predictive value, 90.2% negative predictive value, and 91.7% accuracy. Compared to fiberoptic bronchoscopy, lung ultrasound showed 85.7% sensitivity, 100% specificity, 100% positive predictive value, 95.8% negative predictive value, with of 96.7% accuracy. Conclusion Compared to fiberoptic bronchoscopy and auscultation, lung ultrasound has a very high sensitivity for detecting the proper endotracheal tube position.","PeriodicalId":11437,"journal":{"name":"Egyptian Journal of Anaesthesia","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42654460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Longitudinal analysis of electrolyte prolife in intensive care COVID-19 patients 重症监护COVID-19患者电解质增殖的纵向分析

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Egyptian Journal of Anaesthesia Pub Date : 2023-03-21 DOI: 10.1080/11101849.2023.2192096

M. Abosamak, Ivan Szergyuk, M. H. S. de Oliveira, Sara Mathkar Almutairi, Jawza Salem Alharbi, S. Benoit, G. Lippi, M. Tovt-Korshynska, B. Henry

{"title":"Longitudinal analysis of electrolyte prolife in intensive care COVID-19 patients","authors":"M. Abosamak, Ivan Szergyuk, M. H. S. de Oliveira, Sara Mathkar Almutairi, Jawza Salem Alharbi, S. Benoit, G. Lippi, M. Tovt-Korshynska, B. Henry","doi":"10.1080/11101849.2023.2192096","DOIUrl":"https://doi.org/10.1080/11101849.2023.2192096","url":null,"abstract":"ABSTRACT Introduction According to a substantial body of research, electrolyte abnormalities are a common manifestation in coronavirus disease 2019 (COVID-19) patients and are associated with adverse outcomes. This study aimed to investigate electrolyte imbalances in COVID-19 patients and assess their relation to mortality. Methods Adult COVID-19 patients hospitalized in the Security Forces Hospital in Saudi Arabia from June 8th till August 18th, 2020 were enrolled in this retrospective observational study. We examined baseline characteristics, comorbidities, acute organ injuries, medications, and electrolyte levels including sodium, potassium, chloride, calcium, bicarbonate, phosphate, and magnesium on ICU admission, as well as every following day of ICU stay, until death or discharge. Patients were stratified according to survival, and differences in variables between groups were compared using Mann-Whitney’s U test or Fisher’s exact test. Longitudinal electrolyte profiles were modeled using random intercept linear regression models. Results A total of 60 COVID-19 patients were enrolled. Compared to survivors, non-survivors had significantly higher sodium and phosphate on admission and death, higher potassium and magnesium at death, and significantly lower calcium at death. Abnormalities in admission levels of chloride and bicarbonate were also more frequently observed in non-survivors. Furthermore, in the deceased group, we observed a daily increase in potassium and phosphate levels, and a daily decrease in sodium and chloride. Finally, calcium increased in non-survivors over time, however, not as significantly as in the survivor group. Conclusion Admission levels of electrolytes and changes over the course of ICU stay appear to be associated with mortality in COVID-19 patients.","PeriodicalId":11437,"journal":{"name":"Egyptian Journal of Anaesthesia","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42632132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound -guided erector spinae plane block (ESPB) versus intravenous opioids based analgesia in patients with rib fractures 超声引导竖脊肌平面阻滞（ESPB）与静脉注射阿片类药物用于肋骨骨折患者镇痛的比较

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Egyptian Journal of Anaesthesia Pub Date : 2023-03-15 DOI: 10.1080/11101849.2023.2188729

Soha Elmansy, Mohammed Abdelkhalek, Sherif Farouk, R. Shoukry, A. Khames

{"title":"Ultrasound -guided erector spinae plane block (ESPB) versus intravenous opioids based analgesia in patients with rib fractures","authors":"Soha Elmansy, Mohammed Abdelkhalek, Sherif Farouk, R. Shoukry, A. Khames","doi":"10.1080/11101849.2023.2188729","DOIUrl":"https://doi.org/10.1080/11101849.2023.2188729","url":null,"abstract":"ABSTRACT Background There has been a great interest in the erector spinae plane block (ESPB) to control pain in patients who are presented with rib fractures. ESPB has been shown to achieve adequate analgesia with little adverse effects, although its effectiveness in comparison to other analgesic alternatives has not been sufficiently studied. Aim of the study Our target was to compare the effectiveness of ESPB and opioid based analgesia in relieving pain in rib fractures patients. Methodology Fifty-two patients between 21 and 60 years old, divided into 2 equal groups, received either Ultrasound-guided (US) ESPB with 20 ml of bupivacaine 0.25% or intravenous (IV) morphine 0.1 mg/kg then IV Patient-controlled analgesia (PCA) containing morphine. Assessment of visual analogue scale (VAS) score before and after spirometer exercise at baseline, then at 30 minutes, 6 hours, and 12 hours after the intervention was done. Also Peak Inspiratory Flow Rate (PIFR) was measured by an incentive spirometer, first 12-hour morphine consumption as rescue analgesia was calculated, the incidence of complications was noted, and patients satisfaction was assessed. Results The VAS score was higher in morphine group compared to ESPB group before and after spirometry. PIFR was higher in ESPB group. Less opioid consumption and side effects, along with better patient satisfaction, were recorded in the ESPB group. Conclusion Erector spinae plane block provided superior analgesia and improved respiratory function for IV PCA morphine. Furthermore, ESPB was linked to fewer side effects, less opioid use, and better patient satisfaction.","PeriodicalId":11437,"journal":{"name":"Egyptian Journal of Anaesthesia","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45826522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1