Journal of Life Science and Biomedicine最新文献

{"title":"Clinical characteristics and outcomes of patients with COVID-19–associated acute respiratory distress syndrome","authors":"R. A. Ibadov, S. Ibragimov, H. Alimova, B. B. Burkhonov, R. R. Ibadov","doi":"10.51145/jlsb.2022.4","DOIUrl":"https://doi.org/10.51145/jlsb.2022.4","url":null,"abstract":"Aim. The aim was to analyze the results of intensive care for COVID-19 associated acute respiratory distress syndrome (ARDS) using optimized tactical aspects of respiratory support. Methods. In this prospective study, the comparison group included 436 consecutive patients admitted to the ICU of \"A-block Zangiota-1\" in the period from January 1, 2021 to June 30, 2021 (taking into account the representativeness of the main group), whose the therapeutic and tactical aspects of management were based on the first own experience with results analysis across organizational and therapeutic approaches. The main group included 288 patients admitted from July 1, 2021 to October 1, 2021, whose therapeutic and tactical aspects of management were developed on the basis of a fundamental revision of the differential diagnosis, pathomorphological classification and respiratory mechanics of COVID-19 associated ARDS, as well as taking into account the influence of risk factors for the severe course of the disease and various methods and technologies of respiratory support. Accordingly, adapted and optimized respiratory therapy standards have been applied in main group. Results. The frequency of intubations and transfers to mechanical ventilation had no statistical difference between the groups (p=0.362). In the main group, cases of tracheostomy (73.8%) were significantly (p<0.001) more than the comparison group (14.5%). In the comparison group, the proportion of patients with severe ARDS decreased from 29.6% to 23.8% (p=0.067), and in the main group from 31.0% to 17.0% (p<0.001). The average duration of treatment of patients in the ICU was 22 (from 7 to 32) days in the comparison group and 17 (from 9 to 27) days in the main group (p<0.05). The frequency of deaths in COVID-19 associated ARDS was 11.1% in the main group, which was significantly lower (p=0.036) than the comparison group (16.7%). Among patients on invasive mechanical ventilation (intubation and tracheostomy), the mortality rate was 96.0% in the comparison group and 76.2% in the main group of patients (p = 0.003). Conclusion. Providing respiratory support for COVID-19 associated ARDS, taking into account the individual characteristics of respiratory mechanics, can improve the results of treatment of patients with an increase in the oxygenation index, a decrease in the proportion of cases of severe ARDS, and reduce the mortality rate and the length of stay of patients in the ICU.","PeriodicalId":113264,"journal":{"name":"Journal of Life Science and Biomedicine","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123725101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and antibioresistance of Escherichia coli and Salmonella isolated from lettuce and irrigation water in Ouagadougou, Burkina Faso","authors":"S. Rouamba, N. S. Somda, F. Tapsoba, Asseto Somda, Marie-Laurence Paulette Ouédraogo, E. Kabré, L. Sangaré, A. Savadogo","doi":"10.51145/jlsb.2022.1","DOIUrl":"https://doi.org/10.51145/jlsb.2022.1","url":null,"abstract":"Introduction. The use of partially or untreated wastewater in the irrigation of vegetable crops constitutes a risk of microbiological contamination that can cause diarrhea in the consumer. Aim. This study mainly aimed to assess the level of contamination of irrigation water and lettuce as well as to determine the antibiotic resistance profile of isolated bacteria. Methods. A total of eighty samples of lettuce and ten irrigation waters were collected from the market gardening sites of Boulmiougou, Bissigin, the National School of Public Health and Tanghin. The research of thermotolerant coliforms, Escherichia coli and Salmonella was done following ISO standard methods. Isolated Escherichia coli and Salmonella strains were tested for their resistance profile by using the Kirby-Bauer method with a panel of twenty different antibiotics. Results. Out of the eighty lettuce samples, 68.75% (55) contained thermotolerant coliforms with an average load of 8.75 ×105 CFU g-1. The prevalence of Escherichia coli was 57.5% (46) and Salmonella prevalence was 11.25% (9) including eight strains of Salmonella enterica spp. and one strain of Salmonella enterica arizonea. All irrigation waters were contaminated by thermotolerant coliforms at an average concentration of 3.11×104 CFU/100mL. The prevalence of Escherichia coli in the irrigation waters was 40% (4/10) while Salmonella enterica spp. was 20% (2/10). The highest antibiotic resistance was found in Escherichia coli strains with ampicillin 28.26%, amoxicillin + clavulanic acid 26.09% and tetracycline 19.57%. Conclusion. The water used to irrigate vegetable crops in Ouagadougou could be a major source of contamination of vegetables by microorganisms. In addition, the consumption of lettuce would constitute a risk of propagation of salmonellosis among the population.","PeriodicalId":113264,"journal":{"name":"Journal of Life Science and Biomedicine","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131900179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological, clinical and therapeutic aspects of chronic lymphoid hemopathies observed at the National Reference University Hospital Center (CHU-RN) of N Djamena","authors":"Mbanga Djimadoum, Bessimbaye Nadlaou, Lopiagoto Kemteud Blaise, Choua Ouchemi, M. Mbaissouroum","doi":"10.51145/jlsb.2022.3","DOIUrl":"https://doi.org/10.51145/jlsb.2022.3","url":null,"abstract":"Aim. This study aimed to determine the epidemiological, clinical, therapeutic profile of chronic lymphoid hemopathies (CLH) and the viral factors linked to the genesis of HLCs at the CHU-RN of Ndjamena in Chad. Methods. A descriptive cross-sectional study over two and a half years, from October 2017 to March 2020 at the Hematology Unit of the National Reference University Hospital Center (CHU-RN) of Ndjamena. Were included patients in whom the diagnosis of chronic lymphoid hemopathy had been made. Results. Ninety-eight (98) cases of hematological malignancies were recorded out of 531 hematological consultations including 66 (12.43%) CLH and 67.35% of hematological malignancies with an annual incidence of 26.4 cases. Chronic lymphocytic leukemia (CLL) was 56.06% (n=37) followed by 25.76% (n=17) Malignant non-Hodgkin's lymphoma, 15.15% (n=10) Hodgkin's lymphoma and 3.03 % (n=2) cutaneous lymphoma. A male predominance was observed for all types of CLH. The most represented age groups were those of 51 to 60 years for CLL and 11 to 20 years for lymphomas. Conclusion: This study made it possible to have a better epidemiological knowledge and the viral factors related to the genesis of CLH at the CHU-RN of Ndjamena. It revealed difficulties in biological diagnosis and management, in particular the initiation of chemotherapy.","PeriodicalId":113264,"journal":{"name":"Journal of Life Science and Biomedicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129386926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arthroscopic surgery results for plica syndrome of the knee","authors":"M. Irismetov, Murodbek Bakhodirovich Tadjinazarov","doi":"10.51145/jlsb.2022.2","DOIUrl":"https://doi.org/10.51145/jlsb.2022.2","url":null,"abstract":"Aim. This study aimed to carry out a comparative analysis of the treatment results in patients with plica syndrome of the knee. Methods. A total of 425 patients are contributed in the study done during 2018-2019 (main group) and 2014-2017 (comparison group). The main group was consisted of 205 patients who underwent early arthroscopic surgery as the main treatment. The comparison group was consisted of 220 patients who were prescribed conservative therapy for 3 months as the first stage of treatment; in case of ineffectiveness, arthroscopic diagnostics were performed, followed by surgical correction of the pathology of the synovial plica of the knee. Evaluation of the results was carried out after 1 and 3 months (early and immediate postoperative period), 6 and 12 months (long-term postoperative period), and was based on the data of clinical (complaints and physical examination), instrumental (ultrasound and MRI) examination and test results on the scale Lysholm and a special questionnaire IKDC-2000 by comparing these indicators with the data before and after the surgical treatment of patients. Results. The share of excellent and good long-term results was increased from 80.4% to 92.7%, the frequency of specific complications was reduced from 17.3% to 5.4%. Arthroscopic surgery provided successful therapy in 94.6% of cases in patients with pathological synovial folds of the knee. Long-term rehabilitation of more than 6 months was required in 5.4% (11 out of 205) cases, in particular with recurrent synovitis (7 out of 11; 63.6%), chronic pain in the patellofemoral joint (2 out of 11; 18.2%) and the presence of movement restrictions in the knee joint (2 out of 11; 18.2%). Conclusion. The early use of arthroscopic surgery of pathologically altered synovial folds of the knee joint is accompanied by a positive dynamics of points on the Lysholm scale and the IKDC-2000 questionnaire during treatment and is characterized by the possibility of regression of the intra-articular pathological process with a significant increase in the proportion of excellent and good results in the immediate and late postoperative periods.","PeriodicalId":113264,"journal":{"name":"Journal of Life Science and Biomedicine","volume":"201 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115285722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of premenstrual syndrome on multiple sclerosis symptoms in adult female: a retrospective cross-sectional study","authors":"Yosra Elhussein Ibrahim, Soheir Mahmoud Elkosery, Mohamed Abo Elainin, Afaf M Botla","doi":"10.51145/jlsb.2021.13","DOIUrl":"https://doi.org/10.51145/jlsb.2021.13","url":null,"abstract":"Introduction. is a group of symptoms that many women get about a week or two before their period. Multiple sclerosis (MS) is an autoimmune-mediated disorder that affects the central nervous system (CNS). Aim. This study aimed to see the impact of premenstrual syndrome on multiple sclerosis symptoms. Methods. Forty women having MS and complained from PMS, aged 20-35 years, with BMI less than 30 kg/m 2 were selected randomly from Health Insurance Authority in El-Dokki they were assessed during two periods (normal and premenstrual days). The MS symptoms was assessed through functional system scale; fatigue severity scale and numerical scale and also premenstrual symptoms are assessed by PMS tracker. Results. Multiple pairwise comparison tests revealed that there was significant increase in functional system score in premenstrual period (p=0.006), and also in fatigue severity scale in pre-menstrual period (p=0.0001). Numerical rating scale showed that there was significant increase in pain intensity (p=0.0001) which became more prominent in pre-menstrual period. Conclusion. Premenstrual syndrome has an effect on worsening the symptoms of multiple sclerosis. colony-stimulating","PeriodicalId":113264,"journal":{"name":"Journal of Life Science and Biomedicine","volume":"302 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122112274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological, chemical and physical hazards control plans to ensure employees health during dried mango production","authors":"Alain Gustave Yaguibou, B. Tarnagda, S. Zio, Fulbert Nikiéma, F. Tapsoba, J. P. B. Karama, A. Savadogo","doi":"10.51145/jlsb.2021.12","DOIUrl":"https://doi.org/10.51145/jlsb.2021.12","url":null,"abstract":"Introduction. Food safety is an important quality approach that ensures the safety of both food products and the health of consumers and employees. Aim. This study aimed to develop a control plan through the analysis of critical points of the manufacturing process in the dried mango production units in Burkina Faso. Methods. Investigations were carried out within the manufacturing units located in two regions of Hauts Basins and Cascades with four cities: Bobo-Dioulasso, Banfora, Orodara and Toussiana. The use of 5M method made it possible to classify the various factors likely to contribute to the depreciation of mango quality. Results. The results showed that the majority of the manufacturing units are artisanal type and do not comply in terms of installation and sanitation. The equipments are rudimentary. The staff have not been trained in good manufacturing and hygiene practices. This derives from the practical solutions for the control, prevention and monitoring of 15 critical control points (CCP) identified during the production of dried mangoes. The CCP control plan including four control points has been established. Indeed, the implementation of the method requires the strict procedure monitoring. Conclusion. This study provided information on the risks associated with the production of dried mangoes in Burkina Faso. It will allow to produce quality dried mangoes and to preserve the health of employees and consumer’s by reducing Biological, chemical and physical hazards.","PeriodicalId":113264,"journal":{"name":"Journal of Life Science and Biomedicine","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134373837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Esophageal tumors are complicated by dysphagia: results of patients stenting","authors":"Z. Nizamkhodjaev, R. Ligay, A.S., Babajanov, Rasul Rakhmatovich Omonov, Aleksey Olegovich Tsoy, elNar i. NiGmatulliN, O. Fayzullaev, A. Abdukarimov","doi":"10.51145/jlsb.2021.15","DOIUrl":"https://doi.org/10.51145/jlsb.2021.15","url":null,"abstract":"Introduction. Despite advances in therapy, esophageal cancer (EC) is recently became one of most incurable cancers, especially when it leads to dysphagia. Hence there is a need for develop the optimum management options. Aim. This study presents the experience of treating 464 patients with inoperable stages of esophageal cancer. The causes of inoperable behavior in this type of patients have been identified. Methods. A total of 249 patients were subjected to the following various options of minimally invasive interventions: endoscopic diathermotunnelization (EDT) in 38 (15.3%), endoscopic bougienage (EB) in 18 (7.2%) and endoscopic stenting (ES) in 193 (77.5%) patients. Results. Improved methods of minimally invasive interventions, as well as the nature of possible complications during their use were presented. Conclusion. It is concluded that the installation of endoscopic stenting with self-expanding metal stents (SEMS) with an antireflux valve in the treatment of non-operable EC stages with dysphagia syndrome is the most safe, effective and fast treatment method for dysphagia relief with a greater efficiency and the less frequency of complications especially when conventional silicone and rigid stents is used.","PeriodicalId":113264,"journal":{"name":"Journal of Life Science and Biomedicine","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121683693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Results of head and neck burn reconstructive plastic surgery","authors":"A. A. Kayumkhodjaev, Mukhabbat Khalmuratova","doi":"10.51145/jlsb.2021.14","DOIUrl":"https://doi.org/10.51145/jlsb.2021.14","url":null,"abstract":"Aim. The present research aimed to analyze the results of all reconstruction types (microsurgical and axial flaps) in head and neck post-burn cicatricial defects. Methods. The study included 114 patients who underwent flaps autotransplantation with microvascular anastomoses, options for plasty with axial flaps on a preserved (natural) vascular pedicle, plasty with displaced flaps, and free skin plasty for the period from 1995 to 2021. According to the formed groups for comparative analysis, all patients were divided into a comparison group included of 51 patients (1995-2008 year) and the main group with 63 patients (2009-2021 year). Women predominated with 55.6% and 58.8% in the main and comparison groups, respectively. Medium defects (50-120 cm²) of the upper face and neck area prevailed in equal numbers (11.8%). Most of the patients had a median-lateral unilateral post-burn cicatricial deformity. In terms of functional impairments, grade I up to an angle of 90º and degree II up to an angle of 45º was prevailed. Results. The consolidated long-term results of plastic surgery in the functional value were good in the main group in 69.9% of cases, while in the comparison group it was in 47.1%. The aesthetic indicators of the consolidated long-term results of plastic surgery were good in 57.5% of cases of the main group and significantly was lower in the comparison group (33.3% of cases). Unsatisfactory results were observed in 1.4% of cases in the main group and 17.6% in the comparison group. Conclusion. Improvement in head and neck burn reconstructive plastic surgery with various variants of axial flaps made it possible to increase the proportion of uncomplicated postoperative course, shorten the hospital stay and the total duration of all stages of plasty, and, in general, ensured a decrease in the frequency of unsatisfactory functional and aesthetic results.","PeriodicalId":113264,"journal":{"name":"Journal of Life Science and Biomedicine","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116029894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of manually applied device on hand strength and functions in physiotherapists","authors":"Rana Hussein Mohamed, Wadida H. Elsayed, D. Amin","doi":"10.51145/jlsb.2021.9","DOIUrl":"https://doi.org/10.51145/jlsb.2021.9","url":null,"abstract":"","PeriodicalId":113264,"journal":{"name":"Journal of Life Science and Biomedicine","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125322230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of multisensory exercise programme on cognition and functionality in postmenopausal women","authors":"Rawan A. Abd El-Hay, H. Hanafy, H. Kamel, A. M. Mahmoud","doi":"10.51145/jlsb.2021.11","DOIUrl":"https://doi.org/10.51145/jlsb.2021.11","url":null,"abstract":"","PeriodicalId":113264,"journal":{"name":"Journal of Life Science and Biomedicine","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131435376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}