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Douleur Et Analgesie最新文献

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Conditioned Modulation of Pain Depends on Sex, Personal Attributes and the Perceived Characteristics of the Painful Stimulus 疼痛的条件调节取决于性别、个人属性和疼痛刺激的感知特征
Douleur Et Analgesie Pub Date : 2021-01-01 DOI: 10.3166/DEA-2021-0150
G. Reho
{"title":"Conditioned Modulation of Pain Depends on Sex, Personal Attributes and the Perceived Characteristics of the Painful Stimulus","authors":"G. Reho","doi":"10.3166/DEA-2021-0150","DOIUrl":"https://doi.org/10.3166/DEA-2021-0150","url":null,"abstract":"Characteristics of noxious stimuli and personal attributes shape our experience of pain, but only few studies have rigorously tried to characterize which specific traits impact pain processing. We will discuss the recent article by Firouzian et al. that tries to identify the impact of both positively and negatively regarded personal traits on conditioned pain modulation (CPM): resilience and catastrophization. The authors showed sex-dependent correlation of CPM varying with personal traits as well as characteristics of the conditioning stimulus: unpleasantness and salience.","PeriodicalId":11303,"journal":{"name":"Douleur Et Analgesie","volume":"128 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79225376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
L’évaluation de la douleur chez l’animal de laboratoire 实验动物疼痛的评估
Douleur Et Analgesie Pub Date : 2021-01-01 DOI: 10.3166/DEA-2021-0145
C. Courteix, A. Eschalier, Christophe Mallet
{"title":"L’évaluation de la douleur chez l’animal de laboratoire","authors":"C. Courteix, A. Eschalier, Christophe Mallet","doi":"10.3166/DEA-2021-0145","DOIUrl":"https://doi.org/10.3166/DEA-2021-0145","url":null,"abstract":"","PeriodicalId":11303,"journal":{"name":"Douleur Et Analgesie","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82311028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A New Way to Assess Chronic Pain: Application of Machine Learning on Emotional Body Maps 一种评估慢性疼痛的新方法:机器学习在情绪身体地图上的应用
Douleur Et Analgesie Pub Date : 2021-01-01 DOI: 10.3166/DEA-2021-0156
T. Chauveau
{"title":"A New Way to Assess Chronic Pain: Application of Machine Learning on Emotional Body Maps","authors":"T. Chauveau","doi":"10.3166/DEA-2021-0156","DOIUrl":"https://doi.org/10.3166/DEA-2021-0156","url":null,"abstract":"Recent studies proposed that understanding the connection between emotional states, pain and bodily sensations might help in the understanding of chronic pain conditions. In the targeted article, the authors developed a mobile platform dedicated to chronic back pain patients in order to measure pain, emotions and associated bodily feelings in their daily life conditions. Applying machine learning, they developed two predictive models of future pain.","PeriodicalId":11303,"journal":{"name":"Douleur Et Analgesie","volume":"161 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73452094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kétamine et douleur chronique en France : de la théorie à la pratique 氯胺酮与慢性疼痛在法国:从理论到实践
Douleur Et Analgesie Pub Date : 2021-01-01 DOI: 10.3166/DEA-2021-0155
V. Morel, G. Pickering
{"title":"Kétamine et douleur chronique en France : de la théorie à la pratique","authors":"V. Morel, G. Pickering","doi":"10.3166/DEA-2021-0155","DOIUrl":"https://doi.org/10.3166/DEA-2021-0155","url":null,"abstract":"","PeriodicalId":11303,"journal":{"name":"Douleur Et Analgesie","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86409108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence du microbiote sur la douleur 微生物群对疼痛的影响
Douleur Et Analgesie Pub Date : 2021-01-01 DOI: 10.3166/DEA-2021-0144
S. Gervason, Manon Defaye, D. Ardid, Jonathan Berthon, Christophe Altier, E. Filaire, F. A. Carvalho
{"title":"Influence du microbiote sur la douleur","authors":"S. Gervason, Manon Defaye, D. Ardid, Jonathan Berthon, Christophe Altier, E. Filaire, F. A. Carvalho","doi":"10.3166/DEA-2021-0144","DOIUrl":"https://doi.org/10.3166/DEA-2021-0144","url":null,"abstract":"De plus en plus d’etudes indiquent que le microbiote intestinal pourrait jouer un role important sur les fonctions du systeme nerveux en modulant l’activite des cellules nerveuses. Il a ete montre que les produits derives des bacteries peuvent influencer la perception de la douleur. De plus, des perturbations du microbiote (ou dysbiose) sont souvent associees a des pathologies intestinales ou extraintestinales comme des desordres neurodegeneratifs ou des troubles developpementaux. Cette revue presente les etudes precliniques et cliniques mettant en evidence un impact du microbiote sur la perception de la douleur dans differents contextes pathologiques. Le lien entre le microbiote et l’activation des neurones est discute au travers de l’interaction directe hote–microbiote qui implique l’activation des nocicepteurs par les composes ou metabolites microbiens. De nouvelles etudes sur l’interaction entre le microbiote et le systeme nerveux devraient conduire a l’identification de nouveaux ligands microbiens et de medicaments ciblant les recepteurs de l’hote, qui pourraient a terme ameliorer la gestion de la douleur chronique et le « bien-etre ».","PeriodicalId":11303,"journal":{"name":"Douleur Et Analgesie","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84332318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sensorialité sous kétamine 氯胺酮下的感觉
Douleur Et Analgesie Pub Date : 2021-01-01 DOI: 10.3166/DEA-2021-0154
V. Barfety-Servignat, A. Sallet
{"title":"Sensorialité sous kétamine","authors":"V. Barfety-Servignat, A. Sallet","doi":"10.3166/DEA-2021-0154","DOIUrl":"https://doi.org/10.3166/DEA-2021-0154","url":null,"abstract":"Comme tout medicament, la ketamine a une action sur les plans sensoriel et psychique chez tout sujet. Que vivent et que nous rapportent les patients sous ketamine de leurs sensations et plus generalement de la sensorialite sous ketamine ? Il s’agit dans cet article de questionner ce qui se passe pour nos patients qui font l’experience de la ketamine dans la prise en charge des douleurs chroniques et de le mettre en perspective avec la clinique psychopathologique du trauma et de la douleur chronique. Il convient de nous interroger sur la fonction que vient tenir, pour le patient, la demande de ketamine et celle que tient, pour le prescripteur, la proposition d’un tel traitement quand cela fait courir le risque de venir geler un travail d’appropriation d’un corps vecu et capable d’agir sur le monde.","PeriodicalId":11303,"journal":{"name":"Douleur Et Analgesie","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78268361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sphingosine-1-phosphate Receptor Subtype 1 Antagonists may be the Unmet Medical Need for Morphine-induced Hyperalgesia and Antinociceptive Tolerance 鞘氨醇-1-磷酸受体亚型1拮抗剂可能是吗啡诱导的痛觉过敏和抗痛觉耐受性的未满足的医学需求
Douleur Et Analgesie Pub Date : 2021-01-01 DOI: 10.3166/dea-2021-0165
Y. Brik
{"title":"Sphingosine-1-phosphate Receptor Subtype 1 Antagonists may be the Unmet Medical Need for Morphine-induced Hyperalgesia and Antinociceptive Tolerance","authors":"Y. Brik","doi":"10.3166/dea-2021-0165","DOIUrl":"https://doi.org/10.3166/dea-2021-0165","url":null,"abstract":"Opioids such as morphine are frequently used for chronic pain management despite their many adverse effects. Ongoing research aims at either finding new treatments to replace opioids or reducing its heavy adverse effects due to long-term use: opioid-induced hyperalgesia and antinociceptive tolerance. In a recent study, Doyle et al. (2020) demonstrate that the activation of sphingosine-1-phosphate receptor subtype 1 (S1PR1) in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in a rodent model of chronic pain. By targeting S1PR1 with molecules with functional antagonistic properties (some of which are FDA-approved for multiple sclerosis treatment), hyperalgesia and tolerance were significantly reduced without modifying morphine pharmacokinetics or efficacy.","PeriodicalId":11303,"journal":{"name":"Douleur Et Analgesie","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69373021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
L’infirmière en pratique avancée dans le domaine de la douleur en Belgique 比利时疼痛领域的高级实践护士
Douleur Et Analgesie Pub Date : 2021-01-01 DOI: 10.3166/dea-2021-0179
S. Vanderheyden, A. Segers
{"title":"L’infirmière en pratique avancée dans le domaine de la douleur en Belgique","authors":"S. Vanderheyden, A. Segers","doi":"10.3166/dea-2021-0179","DOIUrl":"https://doi.org/10.3166/dea-2021-0179","url":null,"abstract":"En Belgique, l’Arrêté royal d’exécution concernant l’infirmière en pratique avancée (IPA) n’a pas encore été publié. Pourtant, cette fonction existe. Nous nous intéresserons à l’infirmière ressource douleur (IRD) qui, dans une fonction transversale, fait un travail d’IPA bien avant sa reconnaissance légale. Depuis 2007, le ministère de la Santé finance des projets de prise en charge de la douleur. En 2013, une équipe algologique multidisciplinaire composée d’un médecin, un/une infirmière et un psychologue a été mise en place dans chaque hôpital aigu en Belgique. Sa mission est de sensibiliser les soignants à la nécessité d’une prise en charge correcte de la douleur dans le but de prévenir l’apparition d’une chronicisation. L’IRD a dû, au fil des années, développer des compétences propres de l’IPA : le jugement clinique, l’information, l’éducation, l’accompagnement, la mobilisation des ressources du patient et de l’équipe infirmière ainsi que la recherche.","PeriodicalId":11303,"journal":{"name":"Douleur Et Analgesie","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69373821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
It Takes Two to Tango: Secondary Entry Pathway for SARS-CoV-2 Induces Analgesia 一个巴掌拍不响:SARS-CoV-2的二次进入途径诱导镇痛
Douleur Et Analgesie Pub Date : 2021-01-01 DOI: 10.3166/dea-2021-0180
R. Weill Rossi
{"title":"It Takes Two to Tango: Secondary Entry Pathway for SARS-CoV-2 Induces Analgesia","authors":"R. Weill Rossi","doi":"10.3166/dea-2021-0180","DOIUrl":"https://doi.org/10.3166/dea-2021-0180","url":null,"abstract":"As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to impact the world, its mechanisms of action begin to unravel. The main entry pathway for SARS-CoV-2 into the cell is thought to be through binding to the angiotensin converting enzyme 2, but it seems another protein can induce its viral entry: neuropilin-1 receptor (NRP-1). NRP-1 is usually bound by vascular endothelial growth factor-A (VEGF-A), a - amongst other- pronociceptive factor. By binding to NRP-1, the Spike protein of SARS-CoV-2 blocks neuronal signaling, reducing the pro-nociceptive implication of VEGF-A. This analgesic role of SARS-CoV-2 gave rise to an increase in screenings for new compounds that could interfere with this pathway. Preventing VEGFA from binding to NRP1 opens new possibilities for therapeutic strategies in the field of neuropathic pain.","PeriodicalId":11303,"journal":{"name":"Douleur Et Analgesie","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69373826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Le parcours de santé en douleur chronique 慢性疼痛中的健康路径
Douleur Et Analgesie Pub Date : 2021-01-01 DOI: 10.3166/dea-2022-0189
D. Gillet
{"title":"Le parcours de santé en douleur chronique","authors":"D. Gillet","doi":"10.3166/dea-2022-0189","DOIUrl":"https://doi.org/10.3166/dea-2022-0189","url":null,"abstract":"Dans le cadre de la refonte du système de santé, la notion de parcours en santé est devenue incontournable. Dans le domaine de la douleur chronique, il s’agit de mettre en œuvre un parcours de santé complexe et coordonné. En effet, les composantes biopsychosociales de la douleur chronique et ses impacts sur la qualité de vie des patients impliquent l’utilisation de thérapies multimodales et la participation de plusieurs professionnels aux compétences et modes d’exercice différents. Il convient donc de trouver des solutions pour coordonner le parcours afin d’obtenir une cohérence des postures diagnostiques et thérapeutiques entre les différents professionnels, pour hiérarchiser les actions àmener et pour rendre lisible à tous les actions mises en œuvre et leurs bénéfices obtenus. La concertation et la formalisation du Projet personnalisé de coordination en santé (PPCS) permettent de répondre à cet objectif.","PeriodicalId":11303,"journal":{"name":"Douleur Et Analgesie","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69373843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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