{"title":"Identifying Proteins Associated with Disease Severity","authors":"O. Samarawickrama, R. Jayatillake, D. Amaratunga","doi":"10.54389/eegc3170","DOIUrl":"https://doi.org/10.54389/eegc3170","url":null,"abstract":"Proteomic studies or studies of protein expression levels are growing swiftly with the steady improvement in technology and knowledge on understanding various anomalies affecting humans. Since differentially expressed proteins have an influence on overall cell functionality, this improves discrimination between healthy and diseased states. Identifying prime proteins offers prospective insights for developing optimized and targeted treatment methods. This research involves analyzing data from an early-stage study whose main purpose was to identify differentially expressed proteins. The presence of 3 progressively serious states of disease (healthy to mild to severe) escalates the importance of this study because there is not much research literature that considers ordinal outcomes in studies of this nature. The analysis can be segregated into 2 stages, univariate and multiprotein analysis. Approach of the univariate analysis was to implement continuation ratio model considering one protein at a time to pick those that exhibits potential ordinality. Penalized continuation ratio model using lasso regularization incorporated with bootstrapping proteins was performed as the next stage to identify protein combinationsthat perform well together. Compound results of the univariate and multi-protein analysis identified 20 most dominant proteins that have the capability to discriminate between the disease states in an ordinal manner satisfactorily. Keywords: Proteomic studies; Ordinal nature; Trend tests; Lasso regularization; Bootstrapping","PeriodicalId":112882,"journal":{"name":"PROCEEDINGS OF THE SLIIT INTERNATIONAL CONFERENCE ON ADVANCEMENTS IN SCIENCES AND HUMANITIES [SICASH]","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117080495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prosecuting Sexual Bribery in Sri Lanka: A study on Sexual Bribery and ‘Consent’ of the Victim","authors":"Kamini Rathnayake","doi":"10.54389/mwsc8918","DOIUrl":"https://doi.org/10.54389/mwsc8918","url":null,"abstract":"The ability to prosecute Sexual Bribery (SB) in Sri Lanka (SL) is owed to statutory interpretation. However, SB of only public servants is considered bribery, whereas SB of private sector employees is considered as a sexual offence, thus entirely misrepresenting the gravity of the offence. While it is vital to address this discrepancy, it is equally important to classify SB under bribery and corruption. International review and research suggest the concept of ‘coerced consent’ to tackle the issues of prosecuting SB under laws for sexual offences. This study analyses that until SL amends its laws to expressly criminalise SB, in both public and private sectors, statutory interpretation of ‘coerced consent’ being incorporated into the legal system of SL seems a promising means to resolve this. Keywords: Sexual Bribery; Sextortion; Coerced Consent; Bribery and Corruption; Bribery Act","PeriodicalId":112882,"journal":{"name":"PROCEEDINGS OF THE SLIIT INTERNATIONAL CONFERENCE ON ADVANCEMENTS IN SCIENCES AND HUMANITIES [SICASH]","volume":"171 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127007245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Right to Information vs. Right to Protect Personal Data: A Guidance from the Decisions of the USA & the European Court of Justice.","authors":"R.W.D.N.K Rajapakse","doi":"10.54389/ohdm8576","DOIUrl":"https://doi.org/10.54389/ohdm8576","url":null,"abstract":"Right to Information (RTI) and right to privacy (RTP) are two basic rights of people in a democratic country. Since personal data consists of a main element of privacy, the right not to disclose one's personal data to a third party is an essential part of the RTP. The citizens of Sri Lanka have had the right of obtaining information that is in the custody of public authorities since 2017 under the RTI Act. When deciding whether requested information will be disclosed or not, the public authority will have to consider the exceptions stipulated in the said Act, including the exception of privacy. However, with the enactment of the Personal Data Protection (PDP) Act in 2022 in Sri Lanka, it is crucial to consider the impact of the said Act on the RTI Act. Under the above context, this research explored the overlapping provisions of these two legislations and the decisions of the USA & the European Court of Justice in similar matters. This research study utilized the qualitative methodology where the researcher studied, analyzed, and synthesized a variety of materials gathered through primary and secondary sources to formulate a conclusion and come up with the study results. Finally, the research revealed that the PDP Act has put the additional liability on the public authorities when considering information requests under the RTI Act. Further, the research has identified some guidance from the decided cases of the USA & the European Court of Justice regarding overlapping provisions. Keywords: Right to information; right to privacy; personal data protection; public authorities.","PeriodicalId":112882,"journal":{"name":"PROCEEDINGS OF THE SLIIT INTERNATIONAL CONFERENCE ON ADVANCEMENTS IN SCIENCES AND HUMANITIES [SICASH]","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131600798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"To Leave or not to Leave: Attitudes of the Undergraduates towards Speaking in an Online ESL Classroom","authors":"Ashani Erandi Peiris","doi":"10.54389/myxd9394","DOIUrl":"https://doi.org/10.54389/myxd9394","url":null,"abstract":"Covid 19 pandemic has affected all sectors in Sri Lanka including education. Online delivery mode was integrated into tertiary education in most of the universities to meet the new challenges. Facilitators of the English as a second language (ESL) classes use effective strategies and platforms to improve English language(L2) proficiency of the students. Improving speaking of the learners in such online ESL classes is challenging. ESL facilitator commonly experienced that some students leave the meeting when they are assigned to do a group activity or a speaking activity. Hence, it is vital to study the attitudes of the students towards speaking in an online class to help them improve speaking. A questionnaire was distributed among the first year, first and second semester students in a non-state university, and one hundred twenty-eight responses were collected. The results of the quantitative data were analysed using the percentages of the responses. As revealed, the main reason to avoid ESL lectures is irregular power cuts. On the other hand, the learners have not clearly identified the importance of L2 speaking. The majority use L2 only for oral exams/ assignments, and some prefer the recording. The decision to leave the online lecture when there are speaking activities is rooted mainly from psychological factors, and then secondly from linguistics factors. With proper guidance the students may change their attitudes towards L2 speaking, and their decision to leave the online lecture would be less. Keywords: Leave, online ESL lectures, Speaking, attitude, factors","PeriodicalId":112882,"journal":{"name":"PROCEEDINGS OF THE SLIIT INTERNATIONAL CONFERENCE ON ADVANCEMENTS IN SCIENCES AND HUMANITIES [SICASH]","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128888024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Forging Ahead with Attitudinal Changes towards an Efficient Practice of Commercial Arbitration in Sri Lanka","authors":"K.G.T Dilhara","doi":"10.54389/cwvg7685","DOIUrl":"https://doi.org/10.54389/cwvg7685","url":null,"abstract":"This study examines the question, of whether the pervading disappointment surrounding the practice of commercial arbitration in Sri Lanka, is due to the assimilation of court practices into commercial arbitration by the legal practitioners. Arbitration as an Alternative Dispute Resolution (ADR) method to judicial processes was introduced with the enactment of Arbitration Act No.11 of 1995 and hailed as an effective ADR for the resolution of commercial disputes. Participants were ten senior legal practitioners involved in both court practice as well as commercial arbitration for more than ten years in Sri Lanka. The study used a phenomenological research design to explore the perspectives of ten participants. It was hypothesised that the legal practitioners involved in both court and commercial arbitration practice would have a deeper understanding of the disappointments surrounding commercial arbitration practice and why commercial arbitration has not yielded the anticipated result of efficiency in dispute resolution over court practice. The results indicated that the same practitioners in court and arbitration, bring the same attitudes and skill set practised in courts into commercial arbitration. Thus, the emerging theme is to create an attitudinal shift in the participants of commercial arbitration for the speedy resolution of disputes in comparison to formal court practice. Keywords: Commercial arbitration; Alternative Dispute Resolution; speedy resolution of disputes; attitudinal shift.","PeriodicalId":112882,"journal":{"name":"PROCEEDINGS OF THE SLIIT INTERNATIONAL CONFERENCE ON ADVANCEMENTS IN SCIENCES AND HUMANITIES [SICASH]","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127240954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Care of an Adult Patient who underwent a Series of Surgical Interventions for Psoas Abscess Complications with Haemophilia: Case Report","authors":"H. Sepalika, M.D Dinuka, C. Dasanayaka","doi":"10.54389/uwhq1396","DOIUrl":"https://doi.org/10.54389/uwhq1396","url":null,"abstract":"Psoas abscess is a collection of pus in the Iliopsoas muscle compartment. Haemophilia is an inherited congenital bleeding disorder with a lack of clotting factors. Patients with haemophilia commonly bleed in joints and muscles and experience delayed wound healing. Keywords: Psoas Abscess, Haemophilia, Vacuumdressing, Ileostomy,Sigmoidectomy","PeriodicalId":112882,"journal":{"name":"PROCEEDINGS OF THE SLIIT INTERNATIONAL CONFERENCE ON ADVANCEMENTS IN SCIENCES AND HUMANITIES [SICASH]","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117256251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Peiris, Gayani Malwattage, Raveena D Ratnayake, K. Seneviratne, C. N. Peiris
{"title":"In Vitro Antibacterial Activity of Sulphur Nanoparticles as a Possible Application to Control Bacterial Blight Caused by Xanthomonas spp. in Anthurium","authors":"S. Peiris, Gayani Malwattage, Raveena D Ratnayake, K. Seneviratne, C. N. Peiris","doi":"10.54389/zjif6880","DOIUrl":"https://doi.org/10.54389/zjif6880","url":null,"abstract":"Anthurium blight is caused by Xanthomonas spp. which is regarded as the most threatening disease to the anthurium industry worldwide. Therefore, the current study was carried out to determine whether the application of sulphur nanoparticles (SNPs) is a possible solution for treating anthurium cultivars infected with Xanthomonas spp. The bacterium Xanthomonas was isolated using standard methods and a single bacterial colony was isolated using nutrient agar. The colonies were identified as Xanthomonas spp as they were gram-negative, motile rods due to the colony characters like yellow color because of the xanthin produced. The symptoms appeared in the pathogenicity test which was carried out by injecting purified Xanthomonas sp. into disease free anthurium plants confirmed the identification of the bacterial strain. Time-kill assay was conducted using Staphylococcus aureus, Escherichia coli and isolated Xanthomonas spp to investigate the behavior of SNPs. The results showed that suspension treated with 1g of SNPs for 30 minutes inhibited growth of Staphylococcus aureus colonies showing mean number of 7.92 CFU/ml compared to the control (mean number of colonies 9.09 CFU/ml ) treatment following 12 hours incubation. However, Escherichia coli, and isolated gram-negative rods (Xanthomonas spp) did not show positive influence for SNPs when compared to the control treatment. Therefore, further investigation is required to reach firm conclusions about this matter because the antimicrobial activity of SNPs varies depending on the type of target microorganisms, method and solvent used to dissolve SNPs. Keywords: Sulfur nanoparticles; Xanthomonas app; Anthurium; Bacterial blight","PeriodicalId":112882,"journal":{"name":"PROCEEDINGS OF THE SLIIT INTERNATIONAL CONFERENCE ON ADVANCEMENTS IN SCIENCES AND HUMANITIES [SICASH]","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123529966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Fly in the Ointment; Undue Liability on E-commerce Platforms","authors":"Krishanthi Rajaguru","doi":"10.54389/tjpg2930","DOIUrl":"https://doi.org/10.54389/tjpg2930","url":null,"abstract":"Trade is now largely internet-centric, meaning internet is the medium through which most commercial transactions take place in today’s (information) economy. E-commerce has not only provided a greater market, but it also has changed the way businesses operate. This is indeed a platform economy. E-commerce is considered one of the main drivers of recent economic and social developments globally. In Sri Lanka e-commerce is emerging and in its infancy. The industry is currently expected to be operating within the margin of the law and selfregulated. In the absence of a separate law for e-commerce, e-commerce platforms (ecommerce marketplaces) meaning digital storefronts that connect sellers and customers to transact online, are exposed to a higher risk of being unreasonably penalized by applying the existing laws without mitigation. On the other hand, the platform users are left in a desperate situation with no remedy for harm caused. This article explores the responses of advanced jurisdictions such as China, the EU and the USA which are giant e-commerce markets, regarding platform liability. This study concludes that facilitating a business-enabled environment with holistic and innovative strategies that are aligned with social and economic status of the country with a businessfriendly legal landscape that matches the reality of the industry is imperative. Keywords: E-commerce, platform liability; platform law; policy consideration; law reforms.","PeriodicalId":112882,"journal":{"name":"PROCEEDINGS OF THE SLIIT INTERNATIONAL CONFERENCE ON ADVANCEMENTS IN SCIENCES AND HUMANITIES [SICASH]","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122028649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Legal Debate on the Commercial Use of Personal Data - A Discussion of the Eu Gdpr Precedent","authors":"H. Senanayake","doi":"10.54389/pnox5200","DOIUrl":"https://doi.org/10.54389/pnox5200","url":null,"abstract":"Although the adoption of the Personal Data Protection Act No. 9 of 2022 in Sri Lanka marked a significant milestone in the commercial use of personal data, the regulation of data use is often debated among international policymakers due to the inherent controversy of the subject. This is especially seen in the European Union (EU) which has a stringent data protection scheme. In light of this legal debate, the discussion in this study centres around the key concern of appropriate regulation and balancing between two competing rights, namely, the freedom to commercially utilise user data in the digital economy, and the protection of the right to privacy and protection from unlawful processing of personal data of the consumer/user. Such an academic conversation is engaged in by deliberating on the legal implications of commercial use of personal data. To this end, the essay will first examine the existing legal systems for commercially processing personal data with specific attention to the European Union (EU) General Data Protection Regulation (GDPR) of 2016 and the associated case law. Next, the essay will discuss three concerns on the present protectionist trajectory of the law, and its impact on the dual role of the law in the digital economy, i.e. as a facilitator of lawful commercial use of personal data and a guardian of privacy rights of data subjects. Thereafter, the essay will discuss three concerns on the present protectionist trajectory of the law, and its impact on the dual role of the law in the digital economy, i.e., as a facilitator of lawful commercial use of personal data and as a guardian of privacy rights of data subjects. The legal analysis is centralised on the EU personal data protection regime because it is a microcosm of development in general data protection law, which is widely accepted as a global persuasive precedent on the regulation of transnational commercial use of personal data. Keywords: Legal debate, personal data, Eu Gdpr Precedent.","PeriodicalId":112882,"journal":{"name":"PROCEEDINGS OF THE SLIIT INTERNATIONAL CONFERENCE ON ADVANCEMENTS IN SCIENCES AND HUMANITIES [SICASH]","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124740948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raveena D Ratnayake, S. Peiris, Gayani Malwattage, C. N. Peiris
{"title":"Effects of Coconut Water on Micropropagation of Caladium Bicolour Cv ’Thai Beauty’","authors":"Raveena D Ratnayake, S. Peiris, Gayani Malwattage, C. N. Peiris","doi":"10.54389/kdso3301","DOIUrl":"https://doi.org/10.54389/kdso3301","url":null,"abstract":"Caladium bicolour (Aiton) Vent. is an attractive commercial ornamental plant in the horticulture industry which is popular as potted plants for homescaping and as garden plants for landscaping. Propagation of this attractive plant through micropropagation has more benefits than conventional propagation. The current study describes an in vitro multiplication of Caladium bicolour cv ‘Thai Beauty’ with coconut water as a supplement. Shoots derived from leaf explants were cultured on Murashige and Skoog (MS) medium supplemented with 0, 0.5, 1 and 1.5 mg/L (6- Benzylaminopurine) with and without 120 mL/L of coconut water. The results showed that coconut water (CW) with 0.5 and 1.5 mg/L BAP in the medium increased caladium shoot multiplication having an average of 6.67 and 7.75 shoots /shoot, respectively, with a large number of high-quality shoots. Coconut water alone in the medium also produced average of 3.42 shoots/ shoot. Hence, the current protocol provides a direct, cost-effective mass propagation method for large-scale commercial cultivation of caladium. Keywords: Caladium; Micropropagation; Coconut water; 6-benzylaminopurine","PeriodicalId":112882,"journal":{"name":"PROCEEDINGS OF THE SLIIT INTERNATIONAL CONFERENCE ON ADVANCEMENTS IN SCIENCES AND HUMANITIES [SICASH]","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130440643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}