Drug and Therapeutics Bulletin最新文献

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Diagnostic dilemma: drug-induced vasculitis versus systemic vasculitis. 诊断难题:药物性血管炎与全身性血管炎。
Drug and Therapeutics Bulletin Pub Date : 2024-06-10 DOI: 10.1136/dtb.2024.e254736rep
Indira Acharya, David S Weisman, Lanaya Williams Smith, Lois Johanna Arend
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引用次数: 0
▼Ritlecitinib for severe alopecia areata 治疗严重脱发的利特西替尼
Drug and Therapeutics Bulletin Pub Date : 2024-06-01 DOI: 10.1136/dtb.2024.000014
BMJ Publishing Group Ltd
{"title":"▼Ritlecitinib for severe alopecia areata","authors":"BMJ Publishing Group Ltd","doi":"10.1136/dtb.2024.000014","DOIUrl":"https://doi.org/10.1136/dtb.2024.000014","url":null,"abstract":"### What you need to know Alopecia areata is an autoimmune disease against hair follicles, characterised by hair loss of the scalp, face and/or body, with nail involvement (eg, pitting or ridging) in 10–15% of cases.1–3 Human skin biopsy specimens from people with alopecia areata show the overexpression of Janus kinase 3 (JAK3) and, to a lesser extent, JAK1 and JAK2, which are involved in promoting inflammation via T cells and cytokines.4 The prevalence of alopecia areata has been estimated as 0.6% in Europe.5 6 In the UK, the annual incidence was found to be highest in people aged 25–29 years (5.1 per 10 000 males and 4.3 per 10 000 females) and then decreased with age.7 It can affect all ages, races and genders.5 People of Asian ethnicity, and from socially deprived and urban areas are more likely to present with alopecia areata.7 A family history of the condition, or chromosomal disorders such as Down syndrome, may increase the risk of alopecia areata,3 and it may be associated with other autoimmune diseases such as thyroiditis, type 1 diabetes and rheumatoid arthritis.8 It may be a self-limiting condition, especially in the early stages or where there is <25% hair loss. …","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141172920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update patients on gonadal and fetal shielding for diagnostic imaging. 向患者介绍诊断成像的性腺和胎儿屏蔽的最新情况。
Drug and Therapeutics Bulletin Pub Date : 2024-05-29 DOI: 10.1136/dtb.2024.000004
Joanna Girling
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引用次数: 0
Hydrocortisone-induced symptomatic sinus bradycardia. 氢化可的松诱发症状性窦性心动过缓。
Drug and Therapeutics Bulletin Pub Date : 2024-05-29 DOI: 10.1136/dtb.2024.252878rep
Mohammed Ahmed, Success Tobore Oyibo, Shailesh Dalvi, Richard Cowell
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引用次数: 0
Pharmaceutical company payments to NHS trusts 制药公司向国民保健服务托管机构付款
Drug and Therapeutics Bulletin Pub Date : 2024-05-06 DOI: 10.1136/dtb.2024.000031
BMJ Publishing Group Ltd
{"title":"Pharmaceutical company payments to NHS trusts","authors":"BMJ Publishing Group Ltd","doi":"10.1136/dtb.2024.000031","DOIUrl":"https://doi.org/10.1136/dtb.2024.000031","url":null,"abstract":"### Key points Analysis of data from the Disclosure UK database shows that more than 90% of NHS trusts in England received non-research-related payments from pharmaceutical companies between 2015 and 2018.1 The authors of the study used data from the Disclosure UK database (https://search.disclosureuk.org.uk/) which contains details of payments and benefits in kind made by the pharmaceutical industry to organisations and health professionals in the UK.1 Information relating to payments made during 4 years …","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140883239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reducing antibiotic use for acute sinusitis in children 减少儿童急性鼻窦炎的抗生素用量
Drug and Therapeutics Bulletin Pub Date : 2024-05-02 DOI: 10.1136/dtb.2024.000029
BMJ Publishing Group Ltd
{"title":"Reducing antibiotic use for acute sinusitis in children","authors":"BMJ Publishing Group Ltd","doi":"10.1136/dtb.2024.000029","DOIUrl":"https://doi.org/10.1136/dtb.2024.000029","url":null,"abstract":"### Key messages In children with acute sinusitis, antibiotic treatment had minimal benefit on symptom burden and duration, and the effect did not differ between those with and without coloured nasal discharge.1 This double-blind randomised placebo-controlled trial took place in primary care centres in the USA and involved 510 children aged 2–11 years with persistent or worsening symptoms of acute sinusitis and who scored ≥9 on the Pediatric Rhinosinusitis Symptom Scale …","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140831897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increasing awareness of the risk of death from a propanolol overdose 提高对过量服用普萘洛尔致死风险的认识
Drug and Therapeutics Bulletin Pub Date : 2024-05-02 DOI: 10.1136/dtb.2024.000030
BMJ Publishing Group Ltd
{"title":"Increasing awareness of the risk of death from a propanolol overdose","authors":"BMJ Publishing Group Ltd","doi":"10.1136/dtb.2024.000030","DOIUrl":"https://doi.org/10.1136/dtb.2024.000030","url":null,"abstract":"### Key messages A recently published coroner’s report has highlighted concerns that there may be a lack of awareness over the risks associated with an overdose of propranolol.1 A patient who had a history of mental illness was prescribed an antidepressant for anxiety and to help with sleep.1 He also had a history of suicidal ideation and had made previous suicide attempts. After he was discharged from the community mental health team, he consulted his general practitioner (GP) about symptoms of anxiety and physical symptoms including …","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140832064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prenatal use of antiepileptic drugs and childhood psychiatric disorders 产前使用抗癫痫药物与儿童精神障碍
Drug and Therapeutics Bulletin Pub Date : 2024-04-27 DOI: 10.1136/dtb.2024.000026
BMJ Publishing Group Ltd
{"title":"Prenatal use of antiepileptic drugs and childhood psychiatric disorders","authors":"BMJ Publishing Group Ltd","doi":"10.1136/dtb.2024.000026","DOIUrl":"https://doi.org/10.1136/dtb.2024.000026","url":null,"abstract":"### Key learning points A registry-based study has reinforced the need for safety warnings against using valproate during pregnancy because of an increased risk of early-onset developmental disorders in exposed children.1 This prospective cohort study used data on live-born singleton children of mothers with epilepsy from five Nordic countries to examine the association between prenatal use of antiepileptic medication and psychiatric and developmental disorders in exposed offspring.1 Children were followed up from birth until the …","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140809356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytisine for smoking cessation. 用于戒烟的 Cytisine。
Drug and Therapeutics Bulletin Pub Date : 2024-04-25 DOI: 10.1136/dtb.2024.000009
{"title":"Cytisine for smoking cessation.","authors":"","doi":"10.1136/dtb.2024.000009","DOIUrl":"https://doi.org/10.1136/dtb.2024.000009","url":null,"abstract":"","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":"10 7","pages":"71-76"},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140658387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Recent updates from the BNF (BNF 87). BNF 的最新更新(BNF 87)。
Drug and Therapeutics Bulletin Pub Date : 2024-04-25 DOI: 10.1136/dtb.2024.000018
{"title":"Recent updates from the <i>BNF</i> (<i>BNF</i> 87).","authors":"","doi":"10.1136/dtb.2024.000018","DOIUrl":"10.1136/dtb.2024.000018","url":null,"abstract":"<p><p>The BNF is jointly published by the Royal Pharmaceutical Society and BMJ. BNF is published in print twice a year and interim updates are issued and published monthly in the digital versions. The following summary provides a brief description of some recent key changes that have been made to BNF content.</p>","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":" ","pages":"68-70"},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140189589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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