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Drug and Therapeutics Bulletin最新文献

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Polypill primary prevention: panacea or problematic polypharmacy? 复方药物一级预防：灵丹妙药还是有问题的复方药物？
Drug and Therapeutics Bulletin Pub Date : 2025-04-28 DOI: 10.1136/dtb.2025.000013
David Phizackerley
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引用次数: 0
Initiating renin-angiotensin system inhibitors in chronic kidney disease. 启动肾素-血管紧张素系统抑制剂治疗慢性肾脏疾病。
Drug and Therapeutics Bulletin Pub Date : 2025-04-02 DOI: 10.1136/dtb.2023.000052
Anna Katharina Forbes, Hugh Gallagher
{"title":"Initiating renin-angiotensin system inhibitors in chronic kidney disease.","authors":"Anna Katharina Forbes, Hugh Gallagher","doi":"10.1136/dtb.2023.000052","DOIUrl":"10.1136/dtb.2023.000052","url":null,"abstract":"<p><p>Chronic kidney disease (CKD) is a heterogeneous group of disorders characterised by abnormalities in kidney structure or function, present for at least 3 months. Renin-angiotensin system (RAS) inhibitors are established treatments in the management of CKD, reducing the risk of adverse kidney and cardiovascular events. Despite an extensive evidence base and decades of clinical experience, they remain underused, underdosed and frequently discontinued due to concerns about changes in kidney function and hyperkalaemia. In this article, we provide an overview of initiating RAS inhibitors in adults with CKD, highlight current guideline recommendations and offer a practical approach to dealing with the challenges associated with their use.</p>","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":"63 4","pages":"54-58"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medication errors involving intravenous paracetamol in children. 儿童静脉注射扑热息痛的用药错误。
Drug and Therapeutics Bulletin Pub Date : 2025-04-02 DOI: 10.1136/dtb.2024.000073
{"title":"Medication errors involving intravenous paracetamol in children.","authors":"","doi":"10.1136/dtb.2024.000073","DOIUrl":"10.1136/dtb.2024.000073","url":null,"abstract":"","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":" ","pages":"52"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of feminist empowerment messages to sell tests and treatments. 利用女权主义赋权信息来销售检测和治疗。
Drug and Therapeutics Bulletin Pub Date : 2025-04-02 DOI: 10.1136/dtb.2024.000074
Barbara Mintzes
{"title":"Use of feminist empowerment messages to sell tests and treatments.","authors":"Barbara Mintzes","doi":"10.1136/dtb.2024.000074","DOIUrl":"https://doi.org/10.1136/dtb.2024.000074","url":null,"abstract":"","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":"63 4","pages":"50"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metformin-associated lactic acidosis: a serious complication of a common drug. 二甲双胍相关乳酸酸中毒：一种常见药物的严重并发症。
Drug and Therapeutics Bulletin Pub Date : 2025-04-02 DOI: 10.1136/dtb.2025.260592rep
Kanika Ajay Malani, Arkadiy Finn
{"title":"Metformin-associated lactic acidosis: a serious complication of a common drug.","authors":"Kanika Ajay Malani, Arkadiy Finn","doi":"10.1136/dtb.2025.260592rep","DOIUrl":"10.1136/dtb.2025.260592rep","url":null,"abstract":"","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":" ","pages":"59-63"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Semaglutide and nonarteritic anterior ischaemic optic neuropathy. 西马鲁肽与非动脉性前缺血性视神经病变。
Drug and Therapeutics Bulletin Pub Date : 2025-04-02 DOI: 10.1136/dtb.2025.000002
{"title":"Semaglutide and nonarteritic anterior ischaemic optic neuropathy.","authors":"","doi":"10.1136/dtb.2025.000002","DOIUrl":"10.1136/dtb.2025.000002","url":null,"abstract":"","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":" ","pages":"53"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Very small risk of stroke and MI associated with triptans. 与曲坦类药物相关的中风和心肌梗死风险很小。
Drug and Therapeutics Bulletin Pub Date : 2025-04-02 DOI: 10.1136/dtb.2024.000068
{"title":"Very small risk of stroke and MI associated with triptans.","authors":"","doi":"10.1136/dtb.2024.000068","DOIUrl":"10.1136/dtb.2024.000068","url":null,"abstract":"","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":" ","pages":"51"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142964260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute eosinophilic pneumonia-like syndrome post-initiation of vortioxetine. 开始服用伏替西汀后出现急性嗜酸性粒细胞肺炎样综合征。
Drug and Therapeutics Bulletin Pub Date : 2025-03-03 DOI: 10.1136/dtb.2024.e254254rep
Tanya Marie O'Brien
{"title":"Acute eosinophilic pneumonia-like syndrome post-initiation of vortioxetine.","authors":"Tanya Marie O'Brien","doi":"10.1136/dtb.2024.e254254rep","DOIUrl":"10.1136/dtb.2024.e254254rep","url":null,"abstract":"","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":" ","pages":"27-31"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141418281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longer-term outcomes after molnupiravir for COVID-19. 莫那匹韦治疗COVID-19的长期结果。
Drug and Therapeutics Bulletin Pub Date : 2025-03-03 DOI: 10.1136/dtb.2024.000069
{"title":"Longer-term outcomes after molnupiravir for COVID-19.","authors":"","doi":"10.1136/dtb.2024.000069","DOIUrl":"10.1136/dtb.2024.000069","url":null,"abstract":"","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":" ","pages":"35"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142964256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overview of systemic anticancer treatments: conventional cytotoxics. 全身抗癌疗法概述：传统细胞毒性疗法。
Drug and Therapeutics Bulletin Pub Date : 2025-03-03 DOI: 10.1136/dtb.2023.000059
Betty Zhang
{"title":"Overview of systemic anticancer treatments: conventional cytotoxics.","authors":"Betty Zhang","doi":"10.1136/dtb.2023.000059","DOIUrl":"10.1136/dtb.2023.000059","url":null,"abstract":"<p><p>Cancer treatment is rapidly evolving and this review provides healthcare professionals who are not specialists in cancer therapeutics with a broad overview of the role of cancer systemic therapy, with a particular focus on chemotherapy.Historically, the majority of cytotoxic chemotherapy was used in patients with incurable or metastatic disease with the goal of disease control and symptom palliation. Now, with the advent of more effective, targeted systemic therapies (incorporating both cytotoxic and non-cytotoxic agents), systemic therapies are being used in more diverse treatment settings, both to increase the likelihood of cure and to induce prolonged disease remission.Chemotherapy (henceforth referring specifically to cytotoxic chemotherapy) remains important for the treatment of many cancer types. This article will review the principles of chemotherapy and the first-line systemic treatment paradigm of different cancer types. The potential toxicities of chemotherapy will also be described.</p>","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":" ","pages":"37-43"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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