Deutsches Arzteblatt international最新文献_第7页

Care Models for Psychosocial Problems in Primary Care—A Survey on Awareness and Health Policy Assessment. 初级保健中心理社会问题的护理模式——关于意识和卫生政策评估的调查。

IF 6.5 2区医学

Deutsches Arzteblatt international Pub Date : 2024-11-01 DOI: 10.3238/arztebl.m2024.0116

Wolfram J Herrmann, Hendrik Napierala

引用次数: 0

Better Health Strategies for Men. 更好的男性健康战略。

IF 6.5 2区医学

Deutsches Arzteblatt international Pub Date : 2024-11-01 DOI: 10.3238/arztebl.m2024.0084

Doris Bardehle

引用次数: 0

In Reply. 在回答。

IF 6.5 2区医学

Deutsches Arzteblatt international Pub Date : 2024-11-01 DOI: 10.3238/arztebl.m2024.0141

Michael J Stein

引用次数: 0

Criteria for Re-Irradiation. 再次照射的标准。

IF 6.5 2区医学

Deutsches Arzteblatt international Pub Date : 2024-11-01 DOI: 10.3238/arztebl.m2024.0156

Jonas Willmann, Nicolaus Andratschke, Jens Peter Klußmann, Jürgen E Gschwend, Ghazaleh Tabatabai, Maximilian Niyazi

{"title":"Criteria for Re-Irradiation.","authors":"Jonas Willmann, Nicolaus Andratschke, Jens Peter Klußmann, Jürgen E Gschwend, Ghazaleh Tabatabai, Maximilian Niyazi","doi":"10.3238/arztebl.m2024.0156","DOIUrl":"10.3238/arztebl.m2024.0156","url":null,"abstract":"Background: The treatment options for patients with progressive malignant tumors despite primary radiotherapy are often limited. In selected cases, re-irradiation can be offered. This article concerns the selection criteria and results of re-irradiation for certain types of cancer.Methods: This review is based on pertinent publications retrieved by a selective search in PubMed, with particular attention to glio - blastoma, head and neck tumors, and prostatic carcinoma.Results: The published studies of re-irradiation are few in number and often of limited methodological quality. For glioblastoma, a randomized controlled trial (RCT) found that adding re-irradiation to treatment with bevacizumab yielded no significant improvement in either median progression-free survival or median overall survival (hazard ratio [HR] 0.73; p = 0.05 and HR 0.98; p = 0.46, respec - tively). Re-irradiation is a treatment option for locoregional recurrences of head and neck tumors after primary radiotherapy, but it carries a risk of serious side effects. For unresectable recurrences of nasopharyngeal carcinoma, an RCT has shown that hyperfractionated re-irradiation is more effective than normofractionated re-irradiation (overall survival: HR 0.54, p = 0.014). For locally recurrent prostatic carcinoma after radiotherapy, re-irradiation can yield good oncologic outcomes with an acceptable level of urogenital and gastrointestinal side effects (5-year recurrence-free survival: stereotactic body radiation therapy (SBRT), 58%; high dose rate (HDR) brachytherapy, 77%; versus salvage prostatectomy, 72%). RCTs on this topic are lacking.Conclusion: Re-irradiation is a treatment option for selected cancer patients. As the available scientific evidence is limited, multidisciplinary collaboration and participatory decision-making are particularly important.","PeriodicalId":11258,"journal":{"name":"Deutsches Arzteblatt international","volume":" Forthcoming","pages":"725-732"},"PeriodicalIF":6.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142079657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Understanding and Emotional State of Patients About to Undergo Visceral Surgery for Cancer. 癌症内脏手术患者的认知和情绪状态。

IF 6.5 2区医学

Deutsches Arzteblatt international Pub Date : 2024-11-01 DOI: 10.3238/arztebl.m2024.0119

Tina Gürlich, Peter Szatmary, Ulrich Ronellenfitsch, Heike Schmidt, Jörg Kleeff

引用次数: 0

In Reply. 在回答。

IF 6.5 2区医学

Deutsches Arzteblatt international Pub Date : 2024-11-01 DOI: 10.3238/arztebl.m2024.0199

Nils Schulz

引用次数: 0

Movement-Induced Throat Irritation in Sternoclavicular Dislocation. 胸锁关节脱位的运动性咽喉刺激。

IF 6.5 2区医学

Deutsches Arzteblatt international Pub Date : 2024-11-01 DOI: 10.3238/arztebl.m2024.0103

Cornelius Sebastian Fischer, Tina Histing, Gabriel Keller

引用次数: 0

Methemoglobinemia After Accidental Dermal Absorption of P-Chloroaniline. 皮肤意外吸收对氯苯胺后的高铁血红蛋白血症。

IF 6.5 2区医学

Deutsches Arzteblatt international Pub Date : 2024-11-01 DOI: 10.3238/arztebl.m2023.0279

Bernd Herber

引用次数: 0

The Differential Diagnosis of Leg Ulcers. 腿部溃疡的鉴别诊断。

IF 6.5 2区医学

Deutsches Arzteblatt international Pub Date : 2024-11-01 DOI: 10.3238/arztebl.m2024.0133

Joachim Dissemond, Jan-Malte Placke, Maurice Moelleken, Knut Kröger

{"title":"The Differential Diagnosis of Leg Ulcers.","authors":"Joachim Dissemond, Jan-Malte Placke, Maurice Moelleken, Knut Kröger","doi":"10.3238/arztebl.m2024.0133","DOIUrl":"10.3238/arztebl.m2024.0133","url":null,"abstract":"Background: Chronic wounds on the leg (below the knee) are called leg ulcers. They have many causes, and thus patients with leg ulcers are treated by many different kinds of medical specialist. Appproximately 80% of sufferers have chronic venous insufficiency (CVI) and/ or peripheral arterial occlusive disease (PAOD). Knowledge of the relevant differential diagnoses is important for appropriate treatment, particularly for patients with atypical findings or an intractable course.Methods: This article is based on publications retrieved by a selective search in PubMed, including current guidelines and expert recommendations.Results: The diagnostic evaluation of a leg ulcer can be structured according to the ABCDE rule. This involves individualized, targeted history-taking (anamnesis); bacteriological testing; clinical exami - nation; ancillary testing, particularly for perfusion (defective vascular system); and extras, such as biopsies. Specifically, we present in this article the main aspects of the complex diagnostic evaluation of venous leg ulcers, arterial leg ulcers, vasculitis, vasculopathy, calciphylaxis, pyoderma gangrenosum, necrobiosis lipoidica, ecthyma, and squamous cell carcinoma. There remain many unsolved problems, including interactions between the various areas of clinical treatment and the relative paucity of relevant highquality research.Conclusion: A timely differential-diagnostic evaluation for the many diseases that can cause leg ulcers, which require treatment from representatives of many different medical specialties and health professions, is a prerequisite for their effective individualized treatment.","PeriodicalId":11258,"journal":{"name":"Deutsches Arzteblatt international","volume":" Forthcoming","pages":"733-739"},"PeriodicalIF":6.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141901278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sometimes Less Is More. 有时候少即是多。

IF 6.5 2区医学

Deutsches Arzteblatt international Pub Date : 2024-11-01 DOI: 10.3238/arztebl.m2024.0140

Nicolaus Dahlmann, Dietrich Klingmüller

引用次数: 0