International Journal of Clinical Cardiology最新文献

{"title":"COVID-19 mRNA Vaccine Induced Troponinemia - Is the Vaccine a Cardiac Stressor?","authors":"A. Sameer, Brand Malcolm, L. Janette, MacQueen Douglas, Arbach Angela, Bhattarai Samjhauta","doi":"10.23937/2378-2951/1410232","DOIUrl":"https://doi.org/10.23937/2378-2951/1410232","url":null,"abstract":"There have been emerging concerns of myocarditis with Covid-19 vaccines recently which could be from inflammatory or immunogenic response to vaccine components or something else which is yet to be understood. The most common side effects of the vaccine noted in phase three trials were local reactions and few self-remitting systemic reactions. But we cannot overlook the emerging cardiac manifestations associated with COVID-19 vaccine. Here, we report a young healthy male presenting with atypical chest pain found with troponinemia most likely from myopericarditis, three days after his second dose of Pfizer-BNT162b2 vaccine. He was placed on telemetry monitoring and was treated with Aspirin 81 mg, Colchicine 0.6 mg and Ibuprofen. Given his normal body mass index (BMI), renal function, lipids, d-Dimer, transthoracic echocardiogram (TTE), computed tomography angiography (CTA) chest and non-specific findings in electrocardiogram (EKG), and the close temporal relationship of an inflammatory response to his second COVID-19 vaccination dose, we suspect that his cardiac pathology was a result of his response to vaccination and not to underlying atherosclerotic or embolic disease.","PeriodicalId":112011,"journal":{"name":"International Journal of Clinical Cardiology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129925058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CVA to BPA: Using Balloon Pulmonary Angioplasty to Treat Chronic Thromboembolic Pulmonary Hypertension Post Stroke","authors":"Kanda Adinan, Prins Kurt","doi":"10.23937/2378-2951/1410229","DOIUrl":"https://doi.org/10.23937/2378-2951/1410229","url":null,"abstract":"In patients with CTEPH who are not eligible for PTE, BPA may be a treatment option. It is important to diagnose and treat patients early since delays are associated with worse clinical outcomes. We present a case of CTEPH where early diagnosis and treatment resulted in normalization of PA pressures. CAse RePoRt","PeriodicalId":112011,"journal":{"name":"International Journal of Clinical Cardiology","volume":"12 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120990386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Types and Clinical Presentation of Heart Failure among Hypertensive Patients Seen at a Tertiary Hospital in Dar Es Salaam, Tanzania","authors":"Nyaisonga Gervas George, Chillo Pilly","doi":"10.23937/2378-2951/1410230","DOIUrl":"https://doi.org/10.23937/2378-2951/1410230","url":null,"abstract":"Background: Heart failure (HF) is a common complication in patients with hypertension who may present as HF with preserved ejection fraction (HFpEF) or HF with reduced ejection fraction (HFrEF). These categories have different clinical presentations and may require special attention to diagnose, especially when the presentation is HFpEF. The aim of this study was to assess the prevalence, types and clinical presentation of HF among hypertensive patients being followed-up at a tertiary hospital in Tanzania. Methods: We included all known and newly diagnosed hypertensive adults (≥ 18 years) referred for echocardiogram examination at the Muhimbili National Hospital Mloganzila, between June and December 2019. A detailed cardiovascular history, physical, laboratory and echocardiogram examination was performed in all patients. HF was diagnosed according to the Framingham criteria and was further categorized as HFpEF (EF ≥ 50%) or HFrEF (EF < 50%), according to the echocardiography findings. Patients from these two groups were then compared in terms of demographic, clinical, laboratory and echocardiographic characteristics. The chi-square and Student's t test was used to compare categorical and continuous data respectively. A p-value of < 0.05 indicated a statistically significant difference. Results: Out of 633 hypertensive patients seen during the study period, 346 (54.7%) fulfilled the inclusion criteria and were enrolled. Mean ± SD age was 58.3 ± 12.4 years, and 60.4% were women. Mean ± SD systolic and diastolic BP was 152 ± 23 and 91 ± 15, respectively. A total of 102 (29.5%) patients were found to have HF. Three quarters of HF patients (74.5%) had HFpEF and the remaining (25.5%) had HFrEF. In comparison, patients with HFpEF were more likely to be outpatients, older, obese, and with higher mean BP and more concentric left ventricular hypertrophy when compared to those with HFrEF, all p < 0.05. Conclusion: The prevalence of HF among hypertensive patients seen at a tertiary hospital in Tanzania is 29.5%, majority of them having HFpEF. HFpEF differs from HFrEF in terms of BP levels, obesity status and some echocardiographic parameters. These factors need to be carefully examined when HF is suspected in otherwise less symptomatic patients.","PeriodicalId":112011,"journal":{"name":"International Journal of Clinical Cardiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130901581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution of Pediatric Cardiology over the Last 50 Years - Part III","authors":"Rao P Syamasundar","doi":"10.23937/2378-2951/1410225","DOIUrl":"https://doi.org/10.23937/2378-2951/1410225","url":null,"abstract":"Citation: Rao PS (2021) Evolution of Pediatric Cardiology over the Last 50 Years Part II. Int J Clin Cardiol 8:226. doi.org/10.23937/2378-2951/1410226 Accepted: May 27, 2021: Published: May 29, 2021 Copyright: © 2021 Rao PS. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","PeriodicalId":112011,"journal":{"name":"International Journal of Clinical Cardiology","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115290454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implantation of Durable VAD during COVID-19: An Epicenter Experience","authors":"S. Scott, S. David, K. Bernard, S. Kumar, Batsides George, Mody Kanika, A. Mark","doi":"10.23937/2378-2951/1410206","DOIUrl":"https://doi.org/10.23937/2378-2951/1410206","url":null,"abstract":"Ventricular Assist Devices (VAD) serves as an advanced treatment modality for end stage systolic heart failure patients. Implantation of VAD requires a multidisciplinary team approach with in depth family meetings and education sessions to ensure a successful outcome. During the COVID-19 pandemic, multiple new barriers were identified to allow for traditional VAD implantation and post-operative care. Modifications to current processes needed to be developed to accommodate a safe and comprehensive plan. We describe a two patient experience of implantation of durable VAD from the initial United States epicenter area who underwent successful device therapy.","PeriodicalId":112011,"journal":{"name":"International Journal of Clinical Cardiology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132627980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Balloon Induced Dissection of Left Anterior Descending Artery and its Bidirectional Progression Involving Left Circumflex Artery","authors":"S. Santosh Kumar, Aggarwal Puneet, P. Umeshwar","doi":"10.23937/2378-2951/1410209","DOIUrl":"https://doi.org/10.23937/2378-2951/1410209","url":null,"abstract":"Coronary artery dissection is common after balloon angioplasty, few of which may be catastrophic. Here, we report a case of a76-year-old male who had diffuse disease of proximal left anterior descending artery (LAD). LAD was wired with runthrough (Terumo, Japan) and sequentially dilated with 1.5 × 10 and 2 × 10 mm Sapphire semicompliant balloon. After balloon dilatation, dissection at the distal edge of lesion was noticed. As stent could not be tracked and pushed along the lesion as guide catheter used to back out, the guide catheter was changed to extra backup (EBU). This time, wire was seen into the false lumen along with a long segment spiral dissection spreading downward and occluding the circumflex proximally as left circumflex artery was not visible. Dissection of LAD was first sealed with 2.75 × 38 mm Xience Prime everolimus eluting stent. LCx was carefully wired using Sion wire and stented with 2.75 × 23 mm Xience Prime stent, thereby sealing the dissection and restoring LCx. Sion wire in LAD was carefully manuvoured and parked distally into true lumen. The dissection flap was still visible starting from the distal edge of the deployed stent which was sealed with another 2.5 × 28 mm Xience Prime stent achieving TIMI III flow in both LAD and LCx.","PeriodicalId":112011,"journal":{"name":"International Journal of Clinical Cardiology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114141694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haystack Principle - Its Importance in Unearthing the Electrocardiogram in a Patient with Unexplained Syncope","authors":"S. Santosh Kumar, Sharma Awadesh Kumar, Razi Mahmodullah, P. Umeshwar","doi":"10.23937/2378-2951/1410208","DOIUrl":"https://doi.org/10.23937/2378-2951/1410208","url":null,"abstract":"The \"haystack principle\" is of great diagnostic and therapeutic importance to unearth the obscure P waves which gives clue to underlying diagnosis. Here, we report a case of 72-year-old women who came to outdoor department for evaluation of repeated episodes of loss of consciousness. Electrocardiogram revealed complete right bundle branch block pattern with bizarre T wave in lead II, III, and aVF. P wave were not discernible. However, lead aVR revealed well formed P wave with second-degree atrioventricular block. Patient was successfully managed with implantation of permanent pacemaker. Therefore, whenever one is faced with the problem of finding elusive P wave, lead showing the smallest electrical deflection should always be carefully examined to clinch the diagnosis.","PeriodicalId":112011,"journal":{"name":"International Journal of Clinical Cardiology","volume":"54 68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124704509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of Left Ventricular Systolic Dysfunction in Asymptomatic, Incidently Detected Left Bundle Branch Block (LBBB) in Apparently Healthy Individuals: A Prospective Observational Study at a Tertiary Care Cardiac Center in North India","authors":"M. Jan, Ganaye Mohammad Tahir, Hassan Samiera, Bashir Nusrat","doi":"10.23937/2378-2951/1410211","DOIUrl":"https://doi.org/10.23937/2378-2951/1410211","url":null,"abstract":"Background: Left bundle branch block (LBBB) is often associated with significant heart disease and is often the result of myocardial injury, strain or hypertrophy, it can also be seen in patients without any particular clinical disease. The significance of LBBB has not been well studied in subjects without myocardial infarction or pre-existing heart failure. Therefore, we sought to study the incidence of LV systolic dysfunction in asymptomatic, incidentally detected LBBB in apparently healthy individuals. Aims and objectives: To study the incidence of LV systolic dysfunction in asymptomatic incidentally detected LBBB in apparently healthy individuals. Material and methods: A total of 150 patients were enrolled for study over a period of two years after written informed consent was obtained. All patients included in study attended hospital outpatient department for general and routine check-up and where completely asymptomatic. Patients with incidentally detected LBBB on 12 lead surface Electrocardiogram (ECG) were further evaluated by Echocardiography for LV systolic function. Results: The study observed LBBB is more common in males (61.3%) and is very rare below 40 years of age (0.053%). LBBB is common clinical entity after 60 years of age (40% in our group). Our study found asymptomatic LBBB patients have normal LV systolic function, paradoxical septal motion, normal ejection fraction (EF > 50%) in 54% of patients. Asymptomatic LBBB rarely has more than mild LV systolic dysfunction on echocardiography. We found only 2% of patients with EF < 40%). Conclusion: Asymptomatic LBBB is more common in males and is very rare below 40 years of age. Asymptomatic LBBB patients have near normal LV systolic function. Significant numbers of patients with asymptomatic LBBB have subclinical LV systolic dysfunction. Significant LV systolic dysfunction in LBBB is uncommon in asymptomatic patients.","PeriodicalId":112011,"journal":{"name":"International Journal of Clinical Cardiology","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121765583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes and Outcome of Cardiac Function in Children with SARS-CoV-2 Multisystem Inflammatory Syndrome","authors":"Huetz Chloé, Blache Thibault, Montclos Thomas Perouse de, Galoin Claire Bertail, L. Cécile, Bakloul Mohamed, J. Etienne, Perdreau Elodie, Filippo Sylvie Di","doi":"10.23937/2378-2951/1410210","DOIUrl":"https://doi.org/10.23937/2378-2951/1410210","url":null,"abstract":"Background: Cardiac involvement has been reported in children with SARS-CoV-2 inflammatory syndrome. The objectives herein were to assess changes in cardiac parameters and compare cardiac pathologies observed in SARS-CoV-2 to Kawasaki-(KW) and myocarditis-(MY). Methods: Patients < 18 years of age, with symptoms of Kawasaki disease (KW group) and/or of acute myocarditis (MY group) from March 1 to May 31 2020 were included. Clinical, laboratory data, and cardiac parameters were recorded upon diagnosis and at several points over two weeks. Results: Sixteen patients (8 males) diagnosed in the context of SARS-CoV-2 pandemic, were included (8 KW, 8 MY); the mean age was 5.9 years (KW 2.7 years, MY 10.2 years; p = 0.0002). Fever was present in all. Conjunctivitis, buccal inflammation, lymphadenopathies, dermatological lesions were more frequent in KW, chest pain, and gastrointestinal symptoms more frequent in MY. C-reactive protein, procalcitonin, and fibrinogen levels were higher in MY. Platelets were higher, and hemoglobin and hematocrit lower in KW. Troponin and NT pro-BNP were higher in MY. Coronary anomalies were observed in KW, and mitral regurgitation and pericarditis in MY. LV systolic function impairment in MY was concomitant to the highest values of troponin, NT-pro-BNP, CRP, ferritin, D-dimers, and lowest value of lymphocytes and platelets. Mean length of intensive care stay was 7.8 days and that of hospital stay was 9.7 days (MY 5.1 days, KW 14.4 days, p = 0.0008). Systolic function was normalized within 15 days. Diastolic dysfunction appeared after normalization of systolic function. Conclusion: Cardiac injury is parallel to biological changes, as evidenced by serial changes of systolic and diastolic myocardial ultrasound parameters.","PeriodicalId":112011,"journal":{"name":"International Journal of Clinical Cardiology","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131879832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Covid-19 Pandemic and Triggered Acute Myocardial Infarction among Non-Infected Individuals","authors":"H. Ayman, Abu-Hantash Hadi, Tabbalat Ramzi, Al-Mousa Eyas, Madanat Eyadeh, A. Raad, F. Mahmoud, A. AlhaddadImad","doi":"10.23937/2378-2951/1410185","DOIUrl":"https://doi.org/10.23937/2378-2951/1410185","url":null,"abstract":"• Page 1 of 3 • Hammoudeh et al. Int J Clin Cardiol 2020, 7:185 Citation: Hammoudeh A, Abu-Hantash H, Tabbalat R, Al-Mousa E, Madanat E, et al. (2020) The Covid-19 Pandemic and Triggered Acute Myocardial Infarction among Non-Infected Individuals. Int J Clin Cardiol 7:185. doi.org/10.23937/2378-2951/1410185 Received: June 08, 2020; Accepted: June 16, 2020; Published: June 18, 2020 Copyright: © 2020 Hammoudeh A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The Covid-19 Pandemic and Triggered Acute Myocardial Infarction among Non-Infected Individuals","PeriodicalId":112011,"journal":{"name":"International Journal of Clinical Cardiology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126326988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}