IF 2.1 4区医学

Cutis Pub Date : 2024-11-01 DOI: 10.12788/cutis.1124

Solbie Choi, Sarah K Zemlok, JiaDe Yu, Brandon L Adler

引用次数: 0

Emerging Insights in Keloid Pathogenesis and Therapeutics. 瘢痕疙瘩发病机制和治疗的新见解。

IF 2.1 4区医学

Cutis Pub Date : 2024-11-01 DOI: 10.12788/cutis.1122

Noelle Desir, Iain Noel Encarnacion, Susan C Taylor

引用次数: 0

Asymptomatic Papules on the Neck. 颈部无症状丘疹。

IF 2.1 4区医学

Cutis Pub Date : 2024-11-01 DOI: 10.12788/cutis.1119

Jill Wieser, Elise Keshock, Timothy Chang, Bethany Rohr

引用次数: 0

Comparing Patient Care Models at a Local Free Clinic vs an Insurance-Based University Medical Center. 比较当地免费诊所和基于保险的大学医疗中心的病人护理模式。

IF 2.1 4区医学

Cutis Pub Date : 2024-11-01 DOI: 10.12788/cutis.1138

Alice J Lin, Li Wang, Alaina J James

引用次数: 0

Eating Disorder Risk Factors and the Impact of Obesity in Patients With Psoriasis. 银屑病患者饮食失调危险因素及肥胖的影响。

IF 2.1 4区医学

Cutis Pub Date : 2024-11-01 DOI: 10.12788/cutis.1130

Berkay Temel, Ozge Mine Orenay, Nermin Karaosmanoglu

引用次数: 0

Projected 2023 Cost Reduction From Tumor Necrosis Factor α Inhibitor Biosimilars in Dermatology: A National Medicare Analysis. 预计2023年肿瘤坏死因子α抑制剂生物类似药在皮肤科的成本降低：一项国家医疗保险分析。

IF 2.1 4区医学

Cutis Pub Date : 2024-10-01 DOI: 10.12788/cutis.1107

Katie Roster, Christian Gronbeck, Hao Feng

引用次数: 0

Beware the Manchineel: A Case of Irritant Contact Dermatitis. 小心番石榴：一种刺激性接触性皮炎。

IF 2.1 4区医学

Cutis Pub Date : 2024-10-01 DOI: 10.12788/cutis.1123

Maria Munoz, Scott Whitecar, Scott A Norton

{"title":"Beware the Manchineel: A Case of Irritant Contact Dermatitis.","authors":"Maria Munoz, Scott Whitecar, Scott A Norton","doi":"10.12788/cutis.1123","DOIUrl":"https://doi.org/10.12788/cutis.1123","url":null,"abstract":"The manchineel tree (Hippomane mancinella) grows along the sand-vegetation boundary of Caribbean beaches. The tree also can be found in Florida and the US Virgin Islands. All parts of the tree are toxic. Contact with the sap can cause severe irritant dermatitis and keratoconjunctivitis; eating the fruit can be fatal. Indigenous people were well aware of these properties, and early European explorers of the Caribbean coastlines mentioned the dangers of the plant in their writings. However, the medical literature provides scant information on the clinical evaluation and histopathology of manchineel dermatitis. This case report describes a physician (S.A.N.) who developed manchineel dermatitis while traveling in the US Virgin Islands. The dermatitis manifested as folliculocentric pustules. The patient subsequently underwent a skin biopsy, and histopathology showed a subcorneal acantholytic blister and epidermal spongiosis overlying a mixed perivascular infiltrate and follicular necrosis. The area was treated with hot compresses. Complete resolution took 6 weeks. There is no uniformly recommended treatment for manchineel dermatitis; prevention depends on avoiding contact with the tree.","PeriodicalId":11195,"journal":{"name":"Cutis","volume":"114 4","pages":"E14-E17"},"PeriodicalIF":2.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lichenoid Drug Eruption Secondary to Apalutamide Treatment. 阿帕鲁胺治疗继发的地衣类药物皮疹。

IF 2.1 4区医学

Cutis Pub Date : 2024-10-01 DOI: 10.12788/cutis.1133

Madelyn M Class, Kelly McCoy, Farhaan Hafeez, Alan I Westheim

引用次数: 0

Nailing the Nail Biopsy: Surgical Instruments and Their Function in Nail Biopsy Procedures. 指甲活检：手术器械及其在指甲活检中的作用。

IF 2.1 4区医学

Cutis Pub Date : 2024-10-01 DOI: 10.12788/cutis.1104

Rachel C Hill, Apostolos Katsiaunis, Shari R Lipner

引用次数: 0

Treat-to-Target Outcomes With Tapinarof Cream 1% in Phase 3 Trials for Plaque Psoriasis. 1% Tapinarof乳膏治疗斑块型银屑病的3期临床试验

IF 2.1 4区医学

Cutis Pub Date : 2024-10-01 DOI: 10.12788/cutis.1112

April W Armstrong, Robert Bissonnette, Raj Chovatiya, Tina Bhutani, Philip M Brown, Anna M Tallman, Kim A Papp

{"title":"Treat-to-Target Outcomes With Tapinarof Cream 1% in Phase 3 Trials for Plaque Psoriasis.","authors":"April W Armstrong, Robert Bissonnette, Raj Chovatiya, Tina Bhutani, Philip M Brown, Anna M Tallman, Kim A Papp","doi":"10.12788/cutis.1112","DOIUrl":"10.12788/cutis.1112","url":null,"abstract":"The National Psoriasis Foundation (NPF) treatment targets aim to achieve 1% or lower body surface area (BSA) affected after 3 months of treatment. European psoriasis treatment guidelines aim to achieve similar goals based on improvements in Psoriasis Area and Severity Index (PASI) scores. We performed pooled analyses of the PSOARING phase 3 program, which evaluated treat-to-target outcomes for patients treated with tapinarof cream 1% once daily (QD) for up to 52 weeks. Our analyses included 915 patients from PSOARING 1 and PSOARING 2 who had Physician Global Assessment (PGA) scores of 2 or higher before undergoing treatment with tapinarof, including those who received the vehicle in PSOARING 1 and PSOARING 2 and then tapinarof in PSOARING 3. The treatment targets we analyzed included the proportion of patients achieving an absolute BSA of 1% or lower or an absolute total PASI score of 3 or lower. In total, 40% of patients achieved the stringent NPF target of BSA of 1% or lower within 3 months, and 61% achieved a BSA of 1% or lower at any time (median, ~4 months). Furthermore, 75%, 67%, and 50% achieved PASI scores of 3, 2, and 1 or lower, respectively, at any time (median, ~2-6 months). Our results indicated that a high percentage of patients with mild to severe psoriasis can achieve and exceed ambitious treatment targets when treated with topical tapinarof monotherapy for up to 1 year.","PeriodicalId":11195,"journal":{"name":"Cutis","volume":"114 4","pages":"122-127"},"PeriodicalIF":2.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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