Dermatology最新文献

{"title":"Highlighting Migration in Dermatology: Population Characteristics among Patients Seen in a Dermatological Out-Patient Clinic in Southern Sweden.","authors":"Amna Elyas, Åke Svensson, Francesca Sampogna, Slobodan Zdravkovic, Jörg Kupfer, Florence Dalgard","doi":"10.1159/000545938","DOIUrl":"10.1159/000545938","url":null,"abstract":"<p><strong>Introduction: </strong>Migration is an increasing phenomenon and associated with a physical and psychosocial burden on individuals. Little is known about migration and skin health. The objective of this study was to describe the characteristics of patients regarding migration background and dermatological morbidity among adults seen in a dermatological out-patient clinic in Malmö, Sweden.</p><p><strong>Methods: </strong>An observational cross-sectional study was performed in 2017. Dermatological out-patients completed questionnaires and were examined by a dermatologist. Sociodemographic variables including ethnicity and migration status were assessed by self-report. Ethnicity was assessed with country of birth. General and physical health and details about skin disease were self-reported. Stress was assessed by the Perceived Stress Scale (PSS) and with items assessing stressful life events and economic difficulties. Depression and anxiety were assessed with the Patient Health Questionnaire-2 (PHQ-2) and the General Anxiety Disorder Assessment-2 (GAD-2).</p><p><strong>Results: </strong>250 patients were included. 24% were foreign-born (FB) reporting 41 different countries of birth. Mean duration of living in Sweden was 24.4 years. Compared to non-foreign-born (NFB) patients, FB patients were more stressed (PSS mean 17.5 vs. 15.3, p = 0.044), had more economic difficulties (31.0% vs. 14.6%, p = 0.005) and more anxiety (39.7% vs. 24.9%, p = 0.03). There were significantly fewer patients with psoriasis in FB and more with connective tissue disease. FB rated skin disease severity significantly higher than NFB patients.</p><p><strong>Conclusion: </strong>This study reports the multi-ethnic population in an out-patient dermatological clinic in Malmö, Sweden and the difference in distribution of dermatological conditions among FB patients and NFB patients as well as the burden of disease, with higher levels of stress and anxiety in FB patients. These issues will be investigated further by our group in a larger multicentre study.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"287-293"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Health Literacy among Adults with Hidradenitis Suppurativa.","authors":"Nicole D K Koerts, Barbara Horváth","doi":"10.1159/000543286","DOIUrl":"10.1159/000543286","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Health literacy plays an important role in the management of chronic and debilitating skin diseases like hidradenitis suppurativa (HS). Adequate health literacy empowers patients to understand their disease, manage it effectively, and make informed decisions about their health. Exploring the interplay between health literacy and HS is essential to improve healthcare outcomes in this population. This study aimed to assess the prevalence of limited health literacy among HS patients and its associated factors which has never been studied before.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;In this epidemiological cross-sectional study, data were collected via a population-wide survey within the Lifelines Cohort Study in the Netherlands. Health literacy of participants with HS was compared to non-HS controls. The health literacy was measured using six validated questions covering functional, communicative, and critical health literacy. Associations between the characteristics of the HS group and limited health literacy were examined.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Out of 56,084 adult respondents, 1,156 participants with HS were identified. The prevalence of limited functional health literacy was 24.5% in the non-HS group and 26.4% in the HS group. Our findings indicate that limited health literacy among HS patients is associated with higher body mass index (BMI) (26.9 vs. 25.8) (OR: 0.969, 95% CI: 0.941-0.998), lower education level (34.5% vs. 19.9%) (OR: 0.495, 95% CI: 0.350-0.701), lower socioeconomic status (-0.68 vs. -0.58) (OR: 1.194, 95% CI: 1.029-1.386), and more severe disease stage according to the Hurley stage (33.0% vs. 25.8%) (OR: 1.400, 95% CI: 1.005-1.952).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Our study highlights the importance of addressing health literacy in HS patients, given the high prevalence of limited health literacy among this group and associations with higher BMI and more severe disease stage. Limited health literacy may contribute to poorer health outcomes, suboptimal healthcare utilization, elevated healthcare costs, and health disparities. Targeted interventions to improve health literacy could enhance care quality and outcomes for HS patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Health literacy plays an important role in the management of chronic and debilitating skin diseases like hidradenitis suppurativa (HS). Adequate health literacy empowers patients to understand their disease, manage it effectively, and make informed decisions about their health. Exploring the interplay between health literacy and HS is essential to improve healthcare outcomes in this population. This study aimed to assess the prevalence of limited health literacy among HS patients and its associated factors which has never been studied before.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;In this epidemiological cross-sectional study, data were collected via a population-wide survey within the Lifelines Cohort Study in the Netherlands. Hea","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"184-193"},"PeriodicalIF":3.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nodular Vasculitis: Retrospective Study of an Uncommon Disease in a Non-Tuberculosis Endemic Country with Focus on Treatment Modalities and Efficacy.","authors":"Carole Guillet, Xenia Hauser, Andrea Stillhard, Peter Schmid-Grendelmeier, Isabel Kolm","doi":"10.1159/000542488","DOIUrl":"10.1159/000542488","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Nodular vasculitis (NV) is a rare form of panniculitis primarily affecting middle-aged females, presenting as painful, sometimes ulcerated nodules on the dorsal lower legs. Erythema induratum of Bazin (EIB) is a form of NV and is considered a manifestation of cutaneous tuberculin hypersensitivity. This retrospective study aims to analyze demographics, clinicopathological findings, laboratory results, and treatment outcomes of NV in a non-TB endemic country.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Data of NV patients were extracted from the electronic hospital database of the University Hospital Zurich. Patients were included only if histopathologically confirmed diagnosis of NV and sufficient information on demographics, treatment, and follow-up were available.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;We conducted a 20-year retrospective study, including 62 patients with NV. The most common site of involvement was the lower extremities. Disease duration varied from several months to over 20 years. Histopathological examination revealed lobular panniculitis, with or without vasculitis, and granuloma formation. Tuberculosis association was assessed through the QuantiFERON test and mycobacteria PCR, showing positive results in 22 or 37 (59%) tested cases and in 2 out of 27 cases (7.4%), respectively. Comorbidities were found in over half of the patients. Treatment modalities included topical corticosteroids, antitubercular therapy, systemic steroids, and potassium iodide. Almost 50% of all patients experienced relapses despite treatment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Topical steroids, antitubercular therapy, systemic steroids, and potassium iodide showed similar response rates. Tuberculostatic therapy upon detecting latent TB is recommended. Considering the high recurrence rate and potential side effects of systemic therapies, we recommend first-line treatment with potent topical steroids and compression stockings.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Nodular vasculitis (NV) is a rare form of panniculitis primarily affecting middle-aged females, presenting as painful, sometimes ulcerated nodules on the dorsal lower legs. Erythema induratum of Bazin (EIB) is a form of NV and is considered a manifestation of cutaneous tuberculin hypersensitivity. This retrospective study aims to analyze demographics, clinicopathological findings, laboratory results, and treatment outcomes of NV in a non-TB endemic country.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Data of NV patients were extracted from the electronic hospital database of the University Hospital Zurich. Patients were included only if histopathologically confirmed diagnosis of NV and sufficient information on demographics, treatment, and follow-up were available.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;We conducted a 20-year retrospective study, including 62 patients with NV. The most common site of involvement was the lower extremities. Disease duration varied from several months to over 20 years.","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"27-34"},"PeriodicalIF":3.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11793088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethics of Artificial Intelligence-Based Therapy for Treating Psychological Comorbidities Associated with Dermatological Conditions.","authors":"Ryan Scheinkman, Sheila Sharifi, Keyvan Nouri","doi":"10.1159/000545579","DOIUrl":"10.1159/000545579","url":null,"abstract":"","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"306-307"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are JAK1 Inhibitors Safe from Infection for Patients with Atopic Dermatitis? They Inhibit the Functions of G-CSF and Interferons.","authors":"Hiroshi Katayama","doi":"10.1159/000546432","DOIUrl":"10.1159/000546432","url":null,"abstract":"","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"312-314"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144093156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Dose-Response Relationship between Tobacco Smoking and Hidradenitis Suppurativa: Results from an Observational Study of 1,689 Patients.","authors":"Marine Chastagner, Léa Donzier, Farida Benhadou, Axel P Villani, Philippe Guillem","doi":"10.1159/000545833","DOIUrl":"10.1159/000545833","url":null,"abstract":"<p><strong>Introduction: </strong>Available studies show conflicting results on the relationship between smoking characteristics (age at beginning, importance of consumption) and disease characteristics (disease onset, phenotype, and severity). The objective of the study was to better understand the influence of smoking on hidradenitis suppurativa (HS) characteristics.</p><p><strong>Methods: </strong>The clinical characteristics and smoking habits of 1,689 HS patients were assessed and compared between never, past, and active smokers using Student's t, Fisher's exact, and χ2 tests. Association analyses were done using Spearman's method and logistic regressions.</p><p><strong>Results: </strong>There was a positive association between the mean age at smoking onset and the mean age at HS onset (ρ = 0.4; p < 0.001). Smokers were associated with a more severe disease: the number of affected sites was positively associated with the number of pack-years (ρ = 0.126, p = 0.0002). There was also a significant association between active smoking and a poorer quality of life (p < 0.001), as well as increased pain during HS flares (p < 0.003).</p><p><strong>Conclusion: </strong>Smoking early is associated to earlier onset of HS and heavy HS smokers develop a more severe disease in a dose-response manner. These results may support evidence-based counseling efforts for smoking cessation in HS patients and patients at risk of HS.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"371-380"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interleukin-36 Gamma Measurement via Tape Stripping for Distinguishing Paediatric Psoriasis from Atopic Dermatitis.","authors":"Alexandre Docampo-Simón, Isabel Belinchón-Romero, María José Sánchez-Pujol, Enrique Ángel-Gomis, Marina Senent-Valero, Alejandro Botía-Paco, Verónica Sánchez-García, Rubén Hernández-Quiles, Isabel Betlloch","doi":"10.1159/000545914","DOIUrl":"10.1159/000545914","url":null,"abstract":"<p><strong>Introduction: </strong>Paediatric psoriasis is often misdiagnosed, and the overlap condition of psoriasis and atopic dermatitis (AD), known as psoriasis-dermatitis, further complicates accurate identification. Research has shown that interleukin-36 gamma (IL-36γ) measurement via tape stripping can help diagnose complex cases of psoriasis in adults. However, there are no published studies evaluating the applicability of this method in children, especially for distinguishing psoriasis from AD and the overlap condition. We aimed to assess the utility of IL-36γ measurement via tape stripping for distinguishing psoriasis from AD and for predicting the evolution of psoriasis-dermatitis in children and adolescents.</p><p><strong>Methods: </strong>We conducted a cross-sectional diagnostic accuracy study in consecutive cases of psoriasis, AD, and psoriasis-dermatitis, and in healthy controls. IL-36γ concentration was measured using tape stripping and enzyme-linked immunosorbent assay (ELISA). Expert paediatric dermatologists independently confirmed the clinical diagnoses (reference standard).</p><p><strong>Results: </strong>We included 11 children with psoriasis, 11 with AD, 11 with psoriasis-dermatitis, and 10 healthy controls (mean age 8.7 years, 57% female). Mean IL-36γ levels in psoriasis lesions were significantly higher than in AD lesions (144 pg/mL versus 14.4 pg/mL, p = 0.033) and in healthy controls (144 pg/mL versus 10.4 pg/mL, p = 0.037). The IL-36γ tape stripping method demonstrated a sensitivity of 91% and specificity of 91% for distinguishing psoriasis from AD, with an area under the receiver operating characteristic curve of 0.959. The IL-36γ concentrations in participants with psoriasis-dermatitis predicted the evolution to psoriasis or dermatitis in most cases (5 out of 6, 83.3%).</p><p><strong>Conclusion: </strong>IL-36γ measurement via tape stripping offers a promising method for distinguishing psoriasis from AD in children. This non-invasive approach is practical for routine clinical application and demonstrates good sensitivity and specificity, which suggests it could improve early diagnosis and patient outcomes. IL-36γ measurement via tape stripping for distinguishing paediatric psoriasis from AD.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"317-324"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food Insecurity in Hidradenitis Suppurativa: A Cross-Sectional Analysis from the Population-Based All of Us Research Program.","authors":"Shivani Jain, Jonathan Gunasti, Aditya Sood, Ryan Dieudonne, Divya Chopra, Hadar Lev-Tov, Howa Yeung, Lauren A V Orenstein","doi":"10.1159/000546500","DOIUrl":"10.1159/000546500","url":null,"abstract":"<p><strong>Background: </strong>Hidradenitis suppurativa (HS) is a chronic inflammatory cutaneous disease associated with obesity and low socioeconomic status that can have a significant impact on quality of life. Food insecurity (FI) is associated with a higher likelihood of having a chronic health condition. This cross-sectional study was undertaken to assess the association between HS and FI.</p><p><strong>Summary: </strong>We performed secondary analysis of a cross-sectional survey of individuals 18 years and older registered in the National Institutes of Health's All of Us Research Program in May 2024. The study sample was limited to those who had completed the Children's HealthWatch Hunger Vital Sign™ FI screening survey, validated for use in adults in 2017. HS status was assessed among study participants based on ICD-9/10 diagnosis code (705.83 or L73.2). Multivariable logistic regression was used to characterize the association between HS diagnosis and food security status, adjusting for sex, race and ethnicity, age, and income. Among participants with HS, 37/134 (27.6%) screened positive for FI. In comparison, among those without HS, 6,278/56,967 (11%) screened positive. In an adjusted multivariable logistic regression, HS was associated with significantly higher odds of FI (OR: 1.70, 95% CI: 1.09-2.60).</p><p><strong>Key messages: </strong>Study results demonstrated a significant association between HS and FI. Further research is needed to understand specific factors mediating the relationship between HS and FI. The study highlights an opportunity for dermatologists to take an active role in screening for FI in patients with HS and in providing resources as necessary.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"405-409"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnoracial and Geographic Disparities in Global Atopic Dermatitis Clinical Trials: An Update.","authors":"Caitlyn B Dagenet, Sahar Davoudi, Kyla N Price, Jennifer L Hsiao, Vivian Y Shi","doi":"10.1159/000547224","DOIUrl":"10.1159/000547224","url":null,"abstract":"<p><strong>Introduction: </strong>Atopic dermatitis (AD) disproportionally impacts skin of color (SOC) patients, particularly black/African American children. The number of global AD clinical trials is growing exponentially as the AD medication pipeline expands. Thus, we aimed to provide an analysis of racial, ethnic, and geographical disparities in global AD trials.</p><p><strong>Methods: </strong>Race, ethnicity, and location data were extracted from phase 2 and 3 randomized, double-blind, placebo-controlled trials investigating AD therapies from July 2019 to December 2023 on <ext-link ext-link-type=\"uri\" xlink:href=\"http://ClinicalTrials.gov\" xmlns:xlink=\"http://www.w3.org/1999/xlink\">ClinicalTrials.gov</ext-link>. To provide an update, data were compared to similar published data from Br J Dermatol. 2020;183(2):378-380 from January 2009 to July 2019.</p><p><strong>Results: </strong>Twenty-four completed, randomized controlled trials (RCTs) met the search criteria. North America hosted the highest percentage of RCTs. The majority of participants were white, followed by Asian, and black/African American.</p><p><strong>Conclusion: </strong>Despite growing awareness of how AD affects SOC patients, the majority of participants in AD clinical trials are still white. Further efforts to increase reporting and enrollment of diverse participants are critical to further improving clinical trial participant diversity.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"410-414"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and External Validation of the Hidradenitis Suppurativa Cutaneous Abscess Prediction Score-2: A Clinical Decision Support Tool for Diagnosis of Hidradenitis Suppurativa over Cutaneous Abscess.","authors":"Amit Garg, Jonathan Koptyev, Melissa Butt, Joslyn Kirby, Andrew Strunk","doi":"10.1159/000543130","DOIUrl":"10.1159/000543130","url":null,"abstract":"<p><strong>Introduction: </strong>Patients with hidradenitis suppurativa (HS) experience a 10-year diagnosis delay, on average. Accordingly, time to diagnosis represents one of the greatest unmet needs in HS, which to date has not been adequately addressed. A general lack of awareness about HS in the medical community and a notable heterogeneity in clinical presentation, which is most often confused with cutaneous abscess (CA), forms the basis of poor disease recognition and diagnosis delay. Our objective was to develop and validate a prediction model for diagnosis of HS versus site-specific CA.</p><p><strong>Methods: </strong>We performed a cross-sectional study in which the model was developed using a large clinical database and externally validated using a sample of clinical records at Penn State Health. Prediction model discrimination and calibration were evaluated using the c-statistic, calibration intercept/slope, and a flexible calibration curve.</p><p><strong>Results: </strong>Variable selection identified 15 predictors, 7 of which remained after model simplification. The following characteristics were predictive of HS relative to site-specific CA: female sex, increasing age up to 44 years, African American race, race other than white or African American, increasing body mass index, polycystic ovarian syndrome, and acne. The c-statistic of the 7-variable model in validation was 0.77 (95% CI: 0.73-0.80). Calibration intercept and slope were 0.29 (95% CI: 0.14, 0.43) and 1.09 (95% CI: 0.90, 1.28).</p><p><strong>Conclusion: </strong>Clinical characteristics can predict diagnosis of HS over CA in practice without reliance on a specialty-specific examination to identify disease and potentially reduce diagnosis delay.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"194-202"},"PeriodicalIF":3.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}