Der UrologePub Date : 2021-02-01DOI: 10.1007/s00120-021-01470-3
Mitteilungen der Dgu, Rudolf Hohenfellner-Preis
{"title":"Mitteilungen der DGU","authors":"Mitteilungen der Dgu, Rudolf Hohenfellner-Preis","doi":"10.1007/s00120-021-01470-3","DOIUrl":"https://doi.org/10.1007/s00120-021-01470-3","url":null,"abstract":"","PeriodicalId":11122,"journal":{"name":"Der Urologe","volume":"49 1","pages":"259 - 262"},"PeriodicalIF":0.0,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75866386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Der UrologePub Date : 2020-08-31DOI: 10.1007/s00120-020-01304-8
V. Schmitt, S. Bidnur, M. Thi, E. Beraldi, I. Moskalev, V. Yago, M. Bowden, H. Adomat, L. Fazil, J. Jackson, M. Gleave, E. Trenti, D. Folchini, S. Pycha, C. Mian, C. Schwienbacher, E. Hanspeter, A. Pycha, S. Degener
{"title":"Abstracts des 72. Kongresses der Deutschen Gesellschaft für Urologie e. V.","authors":"V. Schmitt, S. Bidnur, M. Thi, E. Beraldi, I. Moskalev, V. Yago, M. Bowden, H. Adomat, L. Fazil, J. Jackson, M. Gleave, E. Trenti, D. Folchini, S. Pycha, C. Mian, C. Schwienbacher, E. Hanspeter, A. Pycha, S. Degener","doi":"10.1007/s00120-020-01304-8","DOIUrl":"https://doi.org/10.1007/s00120-020-01304-8","url":null,"abstract":"","PeriodicalId":11122,"journal":{"name":"Der Urologe","volume":"77 1","pages":"132 - 5"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84727231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Der UrologePub Date : 2020-07-01DOI: 10.1007/s00120-019-01042-6
František Šimon, Florian Steger
{"title":"[The art of surgery in nuce : Introduction to Institutiones chirurgicae (1601) by Johannes Jessenius (1566-1621)].","authors":"František Šimon, Florian Steger","doi":"10.1007/s00120-019-01042-6","DOIUrl":"10.1007/s00120-019-01042-6","url":null,"abstract":"<p><strong>Background: </strong>In 1601, Johannes Jessenius published the surgical work Institutiones chirurgicae, which is of particular importance for the history of surgery in Germany. So far, research has predominantly concentrated on the anatomical works of Jessenius; his surgical work including aspects of urology has not been the subject of investigation.</p><p><strong>Objectives: </strong>In the present article, we analyze the structure, reasoning, and linguistic means used by the author in this work.</p><p><strong>Results: </strong>According to the introduction, surgery comprises three basic components: agens, actor or the surgeon, actio, the activity, that is, the operation, and per quae et quibus actio perficitur, which means instruments and medications. The operations are arranged in contrasts, solutio continuorum-junctio separatorum, the dissolution of the connected-connection of the separate, extirpatio superfluorum-recuperatio deficientium, to eliminate the superfluous-to restore the missing. The description of the instruments is also based on opposite pairs.</p><p><strong>Discussion: </strong>The three elements of surgical work represent a reduction of what is stated in the Hippocratic text De officina. Thus, recognizable here is an ancient tradition, which was also known to the predecessors of Jessenius.</p><p><strong>Conclusions: </strong>At the beginning of the work, aspects of an introduction to the surgical work of the 16th century are briefly recapitulated. Jessenius adheres to this historical tradition including aspects of urology of this work. In the introduction, he refers to various medical writers, without directly adopting the texts. The surgical artistry that Jessenius stands for is of fundamental importance to this day.</p>","PeriodicalId":11122,"journal":{"name":"Der Urologe","volume":"1 1","pages":"829-834"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78326816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Der UrologePub Date : 2020-06-01DOI: 10.1007/s00120-019-01041-7
F G Mildenberger
{"title":"[Steadfast and unconvincible : The eventful life and legacy of Heinrich Dreuw (1874-1934)].","authors":"F G Mildenberger","doi":"10.1007/s00120-019-01041-7","DOIUrl":"10.1007/s00120-019-01041-7","url":null,"abstract":"<p><p>Syphilis is not a deadly disease anymore, thanks to antibiotics. But before their discovery, Paul Ehrlich presented the drug Salvarsan. Its efficacy was doubted and there were many disputes about it. The Berlin physician Heinrich Dreuw had been the most influential opponent-contemporaries and historians described him as being an antisemitic quack, but maybe they were wrong.</p>","PeriodicalId":11122,"journal":{"name":"Der Urologe","volume":"32 1","pages":"713-717"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73164154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Der UrologePub Date : 2020-03-01DOI: 10.1007/s00120-019-01072-0
P Albers, M Bögemann, S Machtens, A S Merseburger, M Schostak, T Steuber, C Wülfing, M De Santis
{"title":"[Changes in the treatment of metastatic prostate cancer-new data and open questions].","authors":"P Albers, M Bögemann, S Machtens, A S Merseburger, M Schostak, T Steuber, C Wülfing, M De Santis","doi":"10.1007/s00120-019-01072-0","DOIUrl":"10.1007/s00120-019-01072-0","url":null,"abstract":"<p><p>The availability of taxane-based chemotherapy and androgen-receptor-targeted agents (ARTAs) have significantly broadened the therapeutic options for patients with metastatic prostate cancer and may also result in longer patient survival. The therapeutic sequence of ARTAs and taxanes may influence outcome and therefore decisions should be made on an individual basis. This article provides guidance for therapeutic decision-making in daily clinical practice by working out criteria that can be used to support individual therapeutic decisions. The focus is on metastatic castration-naive prostate cancer, oligometastatic disease as well as non-metastatic and metastatic castration-resistant prostate cancer.</p>","PeriodicalId":11122,"journal":{"name":"Der Urologe","volume":"53 1","pages":"307-317"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82875570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Der UrologePub Date : 2020-03-01DOI: 10.1007/s00120-019-01046-2
N Ortiz-Brüchle, M Muders, M Toma, I Esposito, A Hartmann, R Stöhr, H Reis, P Wild, J Köllermann, F Bremmer, J Leichsenring, A Stenzinger, S Merkelbach-Bruse, S Kirfel, S Perner, N Hartmann, W Roth, A Jung, T Kirchner, K Schwamborn, N Pfarr, E Dahl, R Knüchel, N T Gaisa
{"title":"[Status of the availability and use of next generation sequencing (NGS) in bladder cancer-a questionnaire within the uropathology working group].","authors":"N Ortiz-Brüchle, M Muders, M Toma, I Esposito, A Hartmann, R Stöhr, H Reis, P Wild, J Köllermann, F Bremmer, J Leichsenring, A Stenzinger, S Merkelbach-Bruse, S Kirfel, S Perner, N Hartmann, W Roth, A Jung, T Kirchner, K Schwamborn, N Pfarr, E Dahl, R Knüchel, N T Gaisa","doi":"10.1007/s00120-019-01046-2","DOIUrl":"10.1007/s00120-019-01046-2","url":null,"abstract":"<p><strong>Background: </strong>Technical advancement and availability of high-throughput analysis has advanced molecular subtyping of most cancers. Thus, new possibilities for precision oncology have emerged.</p><p><strong>Aim: </strong>Therefore, we aimed to collect data regarding availability and use of next generation sequencing (NGS) for urothelial cancer within the uropathology working group of the German Society of Pathology.</p><p><strong>Methods: </strong>We collected data by questionnaires and additionally asked for sequencing results of bladder cancers in the participating institutions.</p><p><strong>Results: </strong>A total of 13 university-affiliated institutes of pathology took part in the survey. All university institutes offer NGS-based molecular panel diagnostics and provide panels covering between 15 and 170 genes. Altogether, only 20 bladder cancers were sequenced in routine diagnostics and for 10 cancers potential targeted treatment options were available.</p><p><strong>Discussion: </strong>So far, despite availability of NGS diagnostics at university institutes of pathology, only few bladder cancer samples have been sequenced. Based on current data from the molecular subtyping of bladder cancers, we recommend a step-by-step protocol with basic immunohistochemistry analysis and subsequent subtype-dependent analyses, e.g., alterations of the fibroblast growth factor receptors (FGFR) or comprehensive gene panel analyses.</p>","PeriodicalId":11122,"journal":{"name":"Der Urologe","volume":"48 1","pages":"318-325"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78515642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}