Der UrologePub Date : 2022-05-01Epub Date: 2022-04-11DOI: 10.1007/s00120-022-01809-4
Rouvier Al-Monajjed, Raúl Felipe Serón-Möller, Jan Philipp Radtke
{"title":"[The IMPACT study-PSA-based prostate screening in Lynch syndrome].","authors":"Rouvier Al-Monajjed, Raúl Felipe Serón-Möller, Jan Philipp Radtke","doi":"10.1007/s00120-022-01809-4","DOIUrl":"10.1007/s00120-022-01809-4","url":null,"abstract":"","PeriodicalId":11122,"journal":{"name":"Der Urologe","volume":"9 1","pages":"534-536"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76903877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Der UrologePub Date : 2022-05-01Epub Date: 2022-04-04DOI: 10.1007/s00120-022-01812-9
Lukas Lunger, Thomas Amiel, Jürgen E Gschwend
{"title":"[Aftercare and adjuvant therapy for advanced renal cell carcinoma].","authors":"Lukas Lunger, Thomas Amiel, Jürgen E Gschwend","doi":"10.1007/s00120-022-01812-9","DOIUrl":"10.1007/s00120-022-01812-9","url":null,"abstract":"<p><p>Specialist care following (nephron-sparing) kidney surgery serves to detect postoperative complications and to monitor kidney function and cardiovascular health. From an oncological point of view, the early detection of local and contralateral recurrences as well as (single) distant metastases in the early disease stages is paramount. This enables the option of metastasis-directed surgery to delay systemic therapies. On the other hand, the early detection of distant metastases can facilitate the initiation of necessary systemic therapies. In general, nephron-sparing surgery is recommended as the first-line treatment of choice for localized renal tumors. Current guidelines recommend a risk-adapted follow-up based on histopathological criteria (pT, pN or R status). For patients with intermediate and high-risk findings, aftercare should be intensified. In addition to routine blood tests, cross-sectional imaging using contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) remain the method of choice. Recently presented results of the phase III KEYNOTE-564 study on the adjuvant therapy with the programmed cell death 1 (PD1) inhibitor pembrolizumab in clear cell, locally advanced renal cell carcinoma (≥ pT1 GII and or ≥ N+) or oligometastatic renal cell carcinoma without evidence of distant metastases (e.g., after metastasis surgery < 1 year after nephrectomy) demonstrated an advantage in terms of disease-free survival compared to follow-up alone. However, overall survival results are pending. Other potentially effective adjuvant concepts including atezolizumab, nivolumab/ipilimumab, everolimus or pembrolizumab/belzutifan are currently being investigated in clinical trials.</p>","PeriodicalId":11122,"journal":{"name":"Der Urologe","volume":"22 1","pages":"495-499"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75258172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Der UrologePub Date : 2022-05-01DOI: 10.1007/s00120-022-01836-1
Preise der Dgu, Maximilian Nitze-Preis, Wolfgang Knipper-Preis, W. Knipper, Mitteilungen der Dgu
{"title":"Mitteilungen der DGU","authors":"Preise der Dgu, Maximilian Nitze-Preis, Wolfgang Knipper-Preis, W. Knipper, Mitteilungen der Dgu","doi":"10.1007/s00120-022-01836-1","DOIUrl":"https://doi.org/10.1007/s00120-022-01836-1","url":null,"abstract":"","PeriodicalId":11122,"journal":{"name":"Der Urologe","volume":"14 1","pages":"553 - 558"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73414747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Der UrologePub Date : 2022-05-01Epub Date: 2022-04-01DOI: 10.1007/s00120-022-01818-3
Laila Schneidewind, Bernhard Kiss
{"title":"[Extended vs. standard lymphadenectomy for the treatment of urothelial carcinoma of the bladder in patients undergoing radical cystectomy].","authors":"Laila Schneidewind, Bernhard Kiss","doi":"10.1007/s00120-022-01818-3","DOIUrl":"10.1007/s00120-022-01818-3","url":null,"abstract":"","PeriodicalId":11122,"journal":{"name":"Der Urologe","volume":"1 1","pages":"530-533"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80326494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
