Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA最新文献

[Effects of penehyclidine hydrochloride or atropine combined with neostigmine for antagonizing residual neuromuscular block on patient's hemodynamics]. 盐酸戊乙奎醚或阿托品联合新斯的明拮抗残余神经肌肉阻滞对患者血流动力学的影响。

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Pub Date : 2005-12-01

Shi-wei Liang, Ye-ming Chen

{"title":"[Effects of penehyclidine hydrochloride or atropine combined with neostigmine for antagonizing residual neuromuscular block on patient's hemodynamics].","authors":"Shi-wei Liang, Ye-ming Chen","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the effects of penehyclidine hydrochloride(PH)/atropine combined with neostigmine for antagonizing residual neuromuscular block on the hemodynamics.Methods: Eighty patients with elective upper abdominal surgery were randomized equally into PH group and atropine group. Five minutes after the completion of surgery, PH 0.02 mg/kg (in PH group) or atropine 0.02 mg/kg (in atropine group) in combination with neostigime 0.03 mg/kg were given intravenously to reverse the residual neuromuscular block. The heart rate (HR), mean arterial pressure (MAP) and end-tidal CO(2) pressure (P(ET)CO(2)) were recorded 5 min before anesthesia induction, 1 min before injection and 2, 5, 10, and 15 min after injection, respectively.Results: During the investigation, HR in PH group did not undergo conspicuous changes (P>0.05). HR after the injection was markedly faster than that before the injection in atropine group (P<0.01) and did not recover till 15 min after the injection (P>0.05). MAP and P(ET)CO(2) showed no evident changes and no significant difference was observed between the two groups during the investigation (P>0.05).Conclusion: Compared with atropine, PH does not obviously affect HR and BP, but atropine may accelerate HR.","PeriodicalId":11097,"journal":{"name":"Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25757269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Effect of chronic enhanced external counterpulsation on arterial endothelial cells of porcine with hypercholesteremia]. 慢性强化体外反搏对高胆固醇血症猪动脉内皮细胞的影响。

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Pub Date : 2005-12-01

Xiao-lin Chen, Xiao-hong He, Yan Zhang, Yue-tao Qian, Lu-guang Liang, Dian-qiu Fang, Cheng-yang Zhan, Zhen-sheng Zheng, Hong Ma

{"title":"[Effect of chronic enhanced external counterpulsation on arterial endothelial cells of porcine with hypercholesteremia].","authors":"Xiao-lin Chen, Xiao-hong He, Yan Zhang, Yue-tao Qian, Lu-guang Liang, Dian-qiu Fang, Cheng-yang Zhan, Zhen-sheng Zheng, Hong Ma","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To verify whether chronic enhanced external counterpulsation (EECP) may repair artery endothelial cells (ECs) damage resulted from hypercholesteremia in pigs.Methods: EECP was performed for 36 hours in pigs with hypercholesteremia and the left descending artery (LDA) was isolated for scanning electron microscopy (SEM). The ECs were collected from the thoracic aorta and analyzed by proteomic technique.Results: The ECs of hypercholesteremia pigs showed irregular arrangement with obvious desquamation of coronary ECs and formation of atherosclerotic plaque, and these lesions were milder in EECP-treated pigs. Six over-expressed proteins were detected in the endothelial cells in EECP-treated pigs in comparison with those of the hypercholesteremia pigs.Conclusion: Chronic EECP helps restore cell morphology and repair functional damage of ECs resulted from hypercholesteremia by regulating endothelial protein expressions, and consequently improves cell adhesion and intracellular metabolism and reduces EC apoptosis.","PeriodicalId":11097,"journal":{"name":"Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25751444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Rat model of Klebsiella pneumoniae-induced severe pneumonia]. [肺炎克雷伯菌致重症肺炎大鼠模型]。

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Pub Date : 2005-12-01

Ye-min Chen, Wen-jie Huang, Sheng-li Li, Kun Liang

{"title":"[Rat model of Klebsiella pneumoniae-induced severe pneumonia].","authors":"Ye-min Chen, Wen-jie Huang, Sheng-li Li, Kun Liang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To explore the diagnostic criteria and physiopathological features of severe bacterial pneumonia in rats.Methods: A total of 60 Sprague Dawleg rats were randomly divided into 3 groups, namely the model group (n=24), observation group (n=24), and control group (n=12). The rats in the former two groups were intratracheally instilled with Klebsiella pneumoniae suspension at different doses, while those in the control group received intratracheal administration of 1 ml saline. On the 2nd, 4th, and 6th days after intratracheal instillation, 1/3 of the rats in each group were killed to determine the hemodynamics, arterial blood gas (ABG), peripheral hemogram, leukocytes and neutrophils in the bronchoalveolar lavage fluid (BALF), followed by pathological examination of the lung.Results: Obvious hemodynamic changes occurred in the rats of the model group on the 5th day and ABG changes appeared on the 4th day. The changes in peripheral hemogram, leukocytes and neutrophils in the BALF, and lung pathology of the rats in the model group were more obvious than those in the observation group on each time point. As the time prolonged, the changes in the hemodynamics, ABG, peripheral hemogram, leukocytes and neutrophils in the BALF and pathology of the lung exacerbated in the model group and observation group, but all these indices in the control group remain unchanged after bacterial inoculation.Conclusion: The severity of pneumonia in rats increases with the dose increment of the administered Klebsiella pneumoniae suspension, which mimics the pathological changes in severe bacterial pneumonia in human.","PeriodicalId":11097,"journal":{"name":"Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25751446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Analysis of drug resistance spectrum and its mechanism in 1017 clinical bacterial isolates]. 1017株临床分离细菌耐药谱及耐药机制分析

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Pub Date : 2005-12-01

Sui-na Geng, Yong-yu Rui, Qian Wang, Cheng-hui Mou, Xiao-hong Zhou, Jie Zhang

{"title":"[Analysis of drug resistance spectrum and its mechanism in 1017 clinical bacterial isolates].","authors":"Sui-na Geng, Yong-yu Rui, Qian Wang, Cheng-hui Mou, Xiao-hong Zhou, Jie Zhang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the drug susceptibility of the clinical bacterial isolates to provide evidence for more adequate use of antibiotics.Methods: Altogether 1017 clinical bacterial isolates were identified by BD Phoenix and tested for resistance against antimicrobial agents by K-B method. WHONET5 was applied for the analysis.Results: The most frequent bacteria detected included P. aeruginosa (19.37%), coagulase-negative Staphylococci (CNS, 17.70%), E. coli (13.27%), S. aureu (SA, 12.09%), E. faecalis (11.8%), and K. pneumoniae (7.57%). In gram-negative isolates, the susceptibility rate of imipenem was 81.5%, and that of ceftazidime was above 70%. The incidences of E.coli and K. pneumoniae isolates producing extended spectrum beta-lactamase (ESBLs) were 34.8% and 45.5% respectively. In gram-positive isolates, the susceptibility rates of vancomycin and Teicoplanin were 98.8% and 100.0% respectively, and those of furazolidone, imipenem, amikacin, piperacillin/ tazobactam were above 70%. The oxacillin resistant rates of CNS and SA were 78.2% and 46.8%.Conclusion: The 1017 clinical bacterial isolates are characterized by high ratio of ESBL production and oxacillin resistance, suggesting the importance of adequate use of antimicrobial agents and effective control measures for reducing the drug resistance and preventing the spread of multi drug- resistant bacteria.","PeriodicalId":11097,"journal":{"name":"Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25756300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Therapeutic effect of phacoemulsification for closed-angle glaucoma]. 超声乳化术治疗闭角型青光眼疗效观察

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Pub Date : 2005-12-01

Min Zhu, Gang-ping Zhao, Lin-li Yu, Jin-xian He, Jian-hong Yu

引用次数: 0

[Magnetic resonance imaging and radiography for diagnosis of lower limb osteosarcoma: a comparative study]. 【磁共振成像与x线摄影诊断下肢骨肉瘤的比较研究】。

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Pub Date : 2005-12-01

Hui Huang, Yan-ping Chen, Guo-hong Cao, Zhi-chun Lin

引用次数: 0

[Effect of primary percutaneous coronary intervention on plasma B-type natriuretic peptide in patients with acute myocardial infarction]. 初步经皮冠状动脉介入治疗对急性心肌梗死患者血浆b型利钠肽的影响。

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Pub Date : 2005-12-01

Jian-qiu Liang, Xiao-xiong Zhou, Yong-guang Huang, Geng-xin Zhang

{"title":"[Effect of primary percutaneous coronary intervention on plasma B-type natriuretic peptide in patients with acute myocardial infarction].","authors":"Jian-qiu Liang, Xiao-xiong Zhou, Yong-guang Huang, Geng-xin Zhang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To observe the effect of primary percutaneous coronary intervention (PCI) on plasma B-type natriuretc peptide (BNP) in patients with acute myocardial infarction (AMI).Methods: Thirty-eight patients with AMI were divided into two groups for PCI (n=26) and conventional treatment (n=12). The plasma BNP levels were measured by fluorescence immunoassay (FIA) in these patients immediately, 24 h, 7 d, and 30 days after admission, and the infarct-related coronary arteries (IRA) were treated only with emergency interventional therapy in PCI group.Results: BNP of the patients in the PCI and conventional treatment group B increased immediately and 24 h after admission, but there was no significant difference between the two groups (243.74+/-75.68 vs 228.65+/-82.32 and 283.42+/-88.66 vs 275.48+/-89.67, P>0.05). BNP in PCI group decreased but that in conventional treatment group increased 7 days after admission, showing significant difference between them (203.63+/-59.42 vs 388.74+/-108.52, P<0.05 ). BNP remained significantly lower in the PCI group than in the other group 30 days after admission (96.31+/-43.22 vs 237.66+/-75.48, P<0.01). Emergency PCI for different IRA resulted in the significant difference in BNP between the patients, and intervention of the left anterior descending artery (LAD) resulted in more obvious BNP reduction in comparison with that due to interventional of the right coronary artery (RCA) and left circumflex coronary artery (LCX). The changes in left ventricular ejection fraction (LVEF) and left ventricular end-diastolic dimension (LVEDD) were correlated to the changes of BNP. The mean BNP in the 3 fatal cases was nearly 10-fold higher than the normal level.Conclusions: BNP of AMI patients decreases on days 7 and 30 after reperfusion therapy with primary PCI, and the reduction can be more obvious 30 days after admission.","PeriodicalId":11097,"journal":{"name":"Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25756192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Therapeutic effects of anterolateral decompression and fixation on thoracolumbar fractures complicated with incomplete paraplegia]. [前外侧减压固定治疗胸腰椎骨折合并不完全截瘫的疗效]。

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Pub Date : 2005-12-01

Wen-xiong Zhu, Xian-yin Liu, Zhong-jia He, Xin-fa Mo, Xue-ming Zhou, Jian-en Guo

{"title":"[Therapeutic effects of anterolateral decompression and fixation on thoracolumbar fractures complicated with incomplete paraplegia].","authors":"Wen-xiong Zhu, Xian-yin Liu, Zhong-jia He, Xin-fa Mo, Xue-ming Zhou, Jian-en Guo","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the clinical effects of anterolateral decompression and fixation on thoracolumbar fractures complicated with incomplete paraplegia.Methods: Thirty-six patients with thoracolumbar fractures complicated with incomplete paraplegia were treated with anterolateral decompression and fixation.Results: The patients were followed up for an average of 18 months, which showed satisfactory recovery of the intervertebral space height and thoracolumbar vertebral curvature. The average Cobb's angle, spinal canal index and Frankel were improved remarkably, and none of the patients developed such complications as break or mobilization of the plate screw.Conclusion: Anterolateral decompression and fixation can directly and completely decompress the vertebral canal, promote the functional recovery of the spinal nerves and reconstruct the alignment of the spine as an ideal approach for treatment of thoracolumbar fractures with obvious spinal canal-occupying lesions or severe kyphos complicated with incomplete paraplegia.","PeriodicalId":11097,"journal":{"name":"Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25756303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Deep chemical burn due to cantharidin: report of one case]. 斑蝥素致深度化学烧伤1例报告。

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Pub Date : 2005-12-01

Li Hu, Xue-wen Qiu

引用次数: 0

[Rapid detection of Streptococcus pneumoniae and Haemophilus influenzae with DNA probes]. DNA探针快速检测肺炎链球菌和流感嗜血杆菌

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Pub Date : 2005-12-01

Hui-zhen Fan, Hua-peng Yu, Wen-jie Huang

{"title":"[Rapid detection of Streptococcus pneumoniae and Haemophilus influenzae with DNA probes].","authors":"Hui-zhen Fan, Hua-peng Yu, Wen-jie Huang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To establish a method for rapid molecular detection of Streptococcus pneumoniae and Haemophilus influenzae in the early stage of infection.Methods: Specific DNA probes for Streptococcus pneumoniae and Haemophilus influenzae and 16 S rRNA universal probe of bacteria were synthesized by polymerase chain reaction (PCR) and labeled with biotin. The DNA of the bacteria, virus and fungi were hybridized with these probes respectively prior to application for examination of the clinical samples.Results: The DNA probes of 263, 351, and 370 bp were amplified by PCR. Streptococcus pneumoniae and Haemophilus influenzae reacted only with their corresponding probes, and no cross reaction of the bacterial universal probe with virus and fungi was noted. The method could detect bacterial DNA in as small amount as 1 ng. Of the 100 sputum specimens, 11 were found to be positive for Streptococcus pneumoniae and 8 for Haemophilus influenzae, with a positivity rate greater than that by sputum culture.Conclusion: DNA probe detection is simple, rapid, and specific for clinical examination of Streptococcus pneumoniae and Haemophilus influenzae.","PeriodicalId":11097,"journal":{"name":"Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25756372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0