Dermatosen in Beruf und Umwelt. Occupation and environment最新文献

{"title":"[Contact allergy of the immediate type to topical use of lidocaine].","authors":"J Budde,&nbsp;A Stary,&nbsp;U Beiteke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>While undergoing urinary bladder catheterization using a lidocaine lubricant, a seven year old boy developed an anaphylactic reaction. Diagnosis of contact sensitization of type I variety following topical application of lidocaine was confirmed by appropriate testing.</p>","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"37 5","pages":"181-2"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13945157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The dangers of olaquindox. Photoallergy, chronic photosensitive dermatitis and extreme increased photosensitivity in the human, hypoaldosteronism in swine].","authors":"S Schauder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The antibiotic olaquindox, an ingredient added to porker feed to increase overall performance, caused a photoallergic contact eczema and subsequently a chronic photosensitive dermatitis with increased UV-A- and UV-B-sensitivity in a breeder of small pigs. Through the use of sun creams he developed an additional (photo)allergic contact eczema to the sunscreens contained in the creams.</p>","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"37 5","pages":"183-5"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13673945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Electronic data processing storage and analysis of allergologic data with reference to epidemiologic and occupational dermatologic aspects].","authors":"T L Diepgen,&nbsp;O Stüben","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>At our contact dermatitis clinic the computer program ALLDAT (Allergy Data System) was developed with the opportunity of storing and analysing different patients data and various kinds of test reactions with regard to epidemiology and occupational dermatology. Because of the internal construction of the data base, high flexibility and optimization of storage (2000 patient/year----1 MB) is achieved. Persons without both program and computer experience are able to enter data, perform analysis and view results after a short period of instruction.</p>","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"37 5","pages":"163-7"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13674001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Hypersensitivity to levobunolol].","authors":"E Schultheiss","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case is described in which, following local application of glaucoma eye drops containing Levobunolol, a recurring allergic contact eczema with periocular localisation occurred. In the course of the epicutaneous allergy testing a positive reaction (crescendo-type) could be clearly demonstrated experimentally against both the eye drops and their active ingredient, levobunolol-hydrochloride, a beta-blocker (beta-sympatholyticum) out of the class of the aryloxypropylamines.</p>","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"37 5","pages":"185-6"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13673946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational dermatoses in workers exposed to epoxy-impregnated fiberglass fabric.","authors":"M Bruze,&nbsp;G Almgren","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In December, 1985, and February, 1986, skin diseases were investigated among workers in a plant producing printed circuit boards made of copper sheets and fiberglass fabric impregnated with a brominated epoxy resin. A questionnaire was sent to all 159 employees, 143 responded (89.9%). Previous or current dermatoses were reported by 84 workers and 79 of these were examined and patch tested. The patch testing was conducted with a standard test series and with products from the work environment. These tests revealed contact allergy to diglycidylether of bisphenol A (\"epoxy\") in 6 persons. Besides these 6 individuals with occupational allergic contact dermatitis, occupational dermatoses were diagnosed in an additional 29 workers; irritant contact dermatitis in 28 and chemical burn in one. Altogether, 35 (22.0%) demonstrated evidence of occupational dermatoses.</p>","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"37 5","pages":"171-6"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13673939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Therapy-induced lindane concentration in breast milk].","authors":"E Senger,&nbsp;I Menzel,&nbsp;H Holzmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Reactions induced by neurotoxic effects with lindane (gamma-hexachlorcyclohexane) after treatment of infants have been reported by different authors. This has led to controversial discussions as to the indication for therapy with lindane in early infancy. To our knowledge there are to date no published reports on the concentration of lindane in mother's milk after local scabies therapy. In a mother treated with lindane for scabies we found elevated levels of lindane in the mother's milk. Compared to average levels of lindane in mother's milk (0.03 ppm, milk-fat) there was a 30-fold increase after three-day treatment and a 66-fold elevation after an additional one-day treatment with lindane. The problems arising and alternative therapy are discussed.</p>","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"37 5","pages":"167-70"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13623204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Gynecomastia caused by drugs].","authors":"J Langer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Gynecomastia may occur as a result of drug application. This paper presents a review of the causative agents and their role in the generation of gynecomastia.</p>","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"37 4","pages":"121-47"},"PeriodicalIF":0.0,"publicationDate":"1989-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13817483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The problem of the \"epicutaneous standard test\"].","authors":"P J Frosch","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"37 4","pages":"152"},"PeriodicalIF":0.0,"publicationDate":"1989-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13930095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Diagnosis and therapy of Raynaud's phenomenon in occupationally-induced vibration trauma].","authors":"B E Roeser,&nbsp;A Stary,&nbsp;K W Rüping","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Raynaud's phenomenon often represents an early symptom of collagen diseases as well as of occlusive vascular disease; it can as well be due to vibration trauma following development of mechanical lesion of the acral capillary system. A rare case of professionally acquired vibration trauma in a miner who developed vasospastic ischaemia after 20 years subterranean work is reported. Non-invasive blood-flow measurements such as thermic relaxation time, transcutaneous O2-pressure, and laser-doppler perfusion rate, represent suitable means of diagnosis and observation of the course of the disease. Combination therapy including both primary inhibition of platelet aggregation as well as improvement of rheological properties has proved to be superior to other treatment plans.</p>","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"37 3","pages":"78-81"},"PeriodicalIF":0.0,"publicationDate":"1989-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13644657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A critical view of the mechanism(s) of toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Implications for human safety assessment.","authors":"K Rozman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been an important issue in occupational and environmental health for nearly two decades. During this period scientists have studied its possible impacts on exposed human populations. At the same time enormous efforts were made to elucidate the mechanism of TCDD action in various biological models. This paper provides a critical view of the advances made towards understanding the mechanism of TCDD action. Major topics discussed include the Ah-receptor hypothesis, TCDD as a thyroid hormone agonist, TCDD and vitamin A deficiency, TCDD's effect on receptor regulation, and its effect on intermediary metabolism including related hormonal responses. Although the exact mechanism of TCDD action is not yet known, more information is available on the toxicity of this compound than perhaps on that of any other substance. This wealth of information allows important conclusions regarding the assessment of acute, as well as of chronic, toxicities of TCDD for humans. There is no documented case of human death as a result of exposure to TCDD. It appears that humans are acutely less sensitive to TCDD than some animal species. The cause of TCDD-induced lethality in rats is a progressive lethal hypoglycemia due to inhibition of gluconeogenesis. Regulation of this metabolic pathway is quite different amongst species, although primates share great similarities. The assumption that the cause of TCDD-induced death in primates, in analogy to rats, is inhibition of gluconeogenesis would suggest that the acute toxicity of TCDD in humans would be in the range seen in rhesus monkeys (70-300 micrograms/kg). These values are about midway between the most (guinea pig) and least (hamster) sensitive species. TCDD is not a genotoxic agent and not an initiator, but promoter of tumor formation. There is considerable evidence that promotion of cancer, like any other chronic end point of toxicity, is a threshold-type biological process. Therefore, a linear extrapolation of the dose-response is an unnecessarily conservative approach in the safety assessment of TCDD. This paper, based on several studies with different end points of toxicity, supports the notion that 10 pg/kg/day of TCDD represent a safe lifetime exposure level for humans with regard to promotion of cancer, porphyria and chloracne.</p>","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"37 3","pages":"81-92"},"PeriodicalIF":0.0,"publicationDate":"1989-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13804328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}