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[8-methoxypsoralen serum content of problem patients in PUVA therapy]. [8-甲氧基补骨脂素在PUVA治疗中的问题患者血清含量]。
Dermatologische Monatschrift Pub Date : 1990-01-01
T Walther, U F Haustein
{"title":"[8-methoxypsoralen serum content of problem patients in PUVA therapy].","authors":"T Walther,&nbsp;U F Haustein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Beside the stage, expression and course of psoriasis as well as the compliance of patients low or abnormal 8-MOP levels are the cause of the ineffectiveness of the PUVA-therapy, as we could demonstrate in 7 of 11 problem cases. Thus, we determined only a maximal 8-MOP concentration of 47 ng/ml serum as an extreme value in one patient and on other patient had his maximal serum peak 3-4 hours after 8-MOP-application and only a value of 8-MOP of 18 ng/ml serum at the recommended time of irradiation. In this connection a first pass mechanism for 8-MOP by a limited biotransformation capacity in the liver is significant and one basic reason for the interindividual variation. Therefore in these cases the knowledge of the individual serum profiles of 8-MOP is helpful to adapt the time of irradiation to the individual necessities and/or to increase the 8-MOP doses.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 5-6","pages":"317-21"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13378585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cryogenic contact therapy of cutaneous lesions of lupus erythematosus]. [低温接触治疗红斑狼疮皮肤病变]。
Dermatologische Monatschrift Pub Date : 1990-01-01
U Wollina, K Prifert
{"title":"[Cryogenic contact therapy of cutaneous lesions of lupus erythematosus].","authors":"U Wollina,&nbsp;K Prifert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report about results in cryo-contact therapy of otherwise resistant cutaneous lesion in lupus erythematosus (LE). Important unwanted side-effects are persistent telangiectasias. Nevertheless, cryo-contact therapy is preferable for selected cutaneous LE lesions.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 2-3","pages":"105-9"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13512964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Stability of metronidazole, prednisolone and dexamethasone in urea-containing Elacutan W dermatologic agent]. [甲硝唑、强的松龙、地塞米松在含脲艾曲坦W皮肤病药中的稳定性研究]。
Dermatologische Monatschrift Pub Date : 1990-01-01
R Heyde, S Dorsch, S Heidenreich, G Illig
{"title":"[Stability of metronidazole, prednisolone and dexamethasone in urea-containing Elacutan W dermatologic agent].","authors":"R Heyde,&nbsp;S Dorsch,&nbsp;S Heidenreich,&nbsp;G Illig","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Metronidazole was investigated in the basic dermatologic agent Elacutan W to improve the topical therapy of rosacea. The suitability of that basic dermatologic agent was verified for metronidazole, prednisolone and dexamethasone by stability tests (UV-spectroscopy, pH) and by in-vitro-liberation-measurements (membrane method). The drugs are stable for a period of 100 days.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 7","pages":"407-15"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13408689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The effect of monochromatic and polychromatic UV irradiation and of 8-MOP on phagocytosis of neutrophilic granulocytes]. [单色、多色紫外线照射及8-MOP对中性粒细胞吞噬的影响]。
Dermatologische Monatschrift Pub Date : 1990-01-01
H Schaarschmidt, M B Müller, T Walther, M Rytter, B Knopf, W Gast
{"title":"[The effect of monochromatic and polychromatic UV irradiation and of 8-MOP on phagocytosis of neutrophilic granulocytes].","authors":"H Schaarschmidt,&nbsp;M B Müller,&nbsp;T Walther,&nbsp;M Rytter,&nbsp;B Knopf,&nbsp;W Gast","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We investigated the inhibition of granulocyte phagocytosis by 8-MOP and monochromatic or polychromatic UV light. After application of 8-MOP and UV there was an additional inactivation compared with UV alone, as expected from studies on other cell species. This additional inhibition of phagocytosis was found to be increasing with 8-MOP level. The action spectra of granulocyte inactivation by 8-MOP and UV involves the investigated UVB range (until 300 nm). A marked inactivation of granulocytes was seen after erythemogenic fluences only. Therefore we assume that inactivation of granulocytes by direct UV action does not play an essential role in UV therapy in vivo.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 8","pages":"475-81"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13378484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subepidermal calcified nodule. 表皮下钙化结节。
Dermatologische Monatschrift Pub Date : 1990-01-01
J Vázquez Doval, J Soto de Delás, M Idoate, E Quintanilla
{"title":"Subepidermal calcified nodule.","authors":"J Vázquez Doval,&nbsp;J Soto de Delás,&nbsp;M Idoate,&nbsp;E Quintanilla","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The subepidermal calcified nodule (SNC), included under the idiopathic cutaneous calcifications, is an infrequent cutaneous process. We report a new case localized on the chin of an 18 month old child. We review the concept gathered from previous literature and we post the possible role which the mast cell may play in the genesis of the said deposits.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 2-3","pages":"133-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13512967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lichen ruber and bullous pemphigoid. 地衣、橡胶和大疱性类天疱疮。
Dermatologische Monatschrift Pub Date : 1990-01-01
P Zloský, J Machácková, V Minovská, O Vohradníková, F Záruba
{"title":"Lichen ruber and bullous pemphigoid.","authors":"P Zloský,&nbsp;J Machácková,&nbsp;V Minovská,&nbsp;O Vohradníková,&nbsp;F Záruba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors describe the case of a male patient, 20 years old, with a rapidly developing picture of disseminated lichen ruber planus together with the formation of vesicles and blisters. Immunofluorescent examination demonstrated lichen ruber associated with bullous pemphigoid. A good therapeutic effect was obtained with a combination of Triamcinolon and Tigason.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 5-6","pages":"357-61"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13378478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dermatologic memorial calendar 1990]. [皮肤病学纪念日历1990]。
Dermatologische Monatschrift Pub Date : 1990-01-01
W Pluskat
{"title":"[Dermatologic memorial calendar 1990].","authors":"W Pluskat","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 12","pages":"771-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13249486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Drug exanthema due to chloral hydrate]. 【水合氯醛所致药疹】。
Dermatologische Monatschrift Pub Date : 1990-01-01
K Lindner, E Prater, H Schubert, S Siegmund
{"title":"[Drug exanthema due to chloral hydrate].","authors":"K Lindner,&nbsp;E Prater,&nbsp;H Schubert,&nbsp;S Siegmund","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report on a female patient with drug eruption due to Sirupus Chlorali hydrati SR. The causal allergen was chloral hydrate itself. This could be identified even by patch test and oral provocation test.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 8","pages":"483-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13299774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Simplified short-term dithranol therapy--on/off schedule]. [简化短期双萘醇治疗-开/关计划]。
Dermatologische Monatschrift Pub Date : 1990-01-01
H Meffert, U Serfling
{"title":"[Simplified short-term dithranol therapy--on/off schedule].","authors":"H Meffert,&nbsp;U Serfling","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 4","pages":"245-6"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13523908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemoglobin A2 and F in patients with psoriasis. 银屑病患者血红蛋白A2和F的变化。
Dermatologische Monatschrift Pub Date : 1990-01-01
N Zlatkov, L Damianova, K Prodanov, N Kiriakova
{"title":"Hemoglobin A2 and F in patients with psoriasis.","authors":"N Zlatkov,&nbsp;L Damianova,&nbsp;K Prodanov,&nbsp;N Kiriakova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>HbA2 and HbF were studied in 91 patients with different forms of psoriasis: 29 with psoriasis vulgaris placata (restricted forms); 31 with psoriasis generalisata and erythroderma psoriaticum; 21 with psoriatic arthritis; 10 with psoriasis pustulosa. Statistically significant increase of HbA2 was established in patients with psoriasis vulgaris placata (restricted forms) as well in patients with psoriatic arthritis. HbF is statistically significant increased in all forms of psoriasis. The authors suggest, that there is probably in psoriasis a disturbance in the synthesis of the globine chains, which is genetically dependent.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 7","pages":"403-6"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12866268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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