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Fungating mass on the breast of a male patient. 一名男性患者乳房上的瘘管肿块。
Dermatology online journal Pub Date : 2024-10-15 DOI: 10.5070/D330564436
Jeremy K Bray, Christina Dai, Olayemi Sokumbi
{"title":"Fungating mass on the breast of a male patient.","authors":"Jeremy K Bray, Christina Dai, Olayemi Sokumbi","doi":"10.5070/D330564436","DOIUrl":"https://doi.org/10.5070/D330564436","url":null,"abstract":"<p><p>Breast cancer is one of the most common malignancies that can lead to cutaneous metastasis. Dermatopathologists often play an important role in the diagnosis of breast cancer metastasis to the skin. Rarely, dermatopathologists render a histopathologic diagnosis of primary breast cancer. We discuss a 51-year-old man with metastatic breast adenocarcinoma who presented after admission to the intensive care unit in the setting of altered mental status and critical anemia. Examination revealed a 14cmx12cm ulcerated, fungating tumor occupying the left breast. A four mm punch biopsy from the mass showed cords of atypical cells infiltrating the mid-to-deep dermis positive for CK7, GATA3, ER and PR. CK20, P40, p63, and TTF1 stains were negative. HER2/NEU immunoperoxidase stain was negative. CA15-3 was elevated at 75U/ml. Taken together, he was diagnosed with primary left breast ductal adenocarcinoma, grade two with subsequent visceral metastases to the bones, lymph nodes, and lungs. Although male breast cancer makes up less than 1% of all breast cancers, its incidence has been increasing worldwide. Recognition of the unique clinical and histologic findings of primary breast carcinoma is important to avoid delay in the diagnosis and initiation of appropriate treatment.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rural access to dermatology services: a call to action. 农村获得皮肤科服务：行动呼吁。
Dermatology online journal Pub Date : 2024-10-15 DOI: 10.5070/D330564425
Bethany Brumbaugh, Jag Lally, Robert Brodell
{"title":"Rural access to dermatology services: a call to action.","authors":"Bethany Brumbaugh, Jag Lally, Robert Brodell","doi":"10.5070/D330564425","DOIUrl":"https://doi.org/10.5070/D330564425","url":null,"abstract":"<p><p>This commentary underscores the urgent issue of limited access to dermatologic care in rural areas, leading to adverse health outcomes. With only 10% of dermatologists practicing in rural America, the \"rural mortality penalty\" contributes to escalating morbidity and mortality. Disparities in dermatologist distribution, particularly in minority-majority counties with lower incomes, worsen health inequities. Despite these challenges, initiatives such as pipeline programs, rural university offices, rural dermatology residency tracks, teledermatology, and Project ECHO (a collaborative model of medical education and care) are promising. This commentary stresses the need for academic dermatologists to recruit more rural medical students and train more residents with a rural upbringing. This predicts future practice in such communities. Immediate action to address the widening rural dermatology gap is needed. The formation of the Rural Access to Dermatology Society, with its first meeting in the spring of 2024 at the annual meeting of the American Academy of Dermatology, is a key part of this process.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A cross-sectional analysis of insurance acceptance among Mohs micrographic surgeons in New York City. 对纽约市莫氏显微手术外科医生接受保险情况的横断面分析。
Dermatology online journal Pub Date : 2024-10-15 DOI: 10.5070/D330564439
Katie Roster, Sumaiya Islam, Farhha Feroz, Shelcie Fabre, Zahidul Islam, Abigail Cline, Shari R Lipner
{"title":"A cross-sectional analysis of insurance acceptance among Mohs micrographic surgeons in New York City.","authors":"Katie Roster, Sumaiya Islam, Farhha Feroz, Shelcie Fabre, Zahidul Islam, Abigail Cline, Shari R Lipner","doi":"10.5070/D330564439","DOIUrl":"https://doi.org/10.5070/D330564439","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comments on a recent paper Jellyfish envenomation with delayed hypersensitivity and concurrent SARS-CoV-2 infection. 对最近发表的一篇论文的评论 水母螫伤伴有迟发性超敏反应和并发 SARS-CoV-2 感染。
Dermatology online journal Pub Date : 2024-10-15 DOI: 10.5070/D330564443
Gerald L Crow, Brenden S Holland
{"title":"Comments on a recent paper Jellyfish envenomation with delayed hypersensitivity and concurrent SARS-CoV-2 infection.","authors":"Gerald L Crow, Brenden S Holland","doi":"10.5070/D330564443","DOIUrl":"https://doi.org/10.5070/D330564443","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personalized melanoma grading system: a presentation of a patient with four melanomas detected over two decades with evolving whole-body imaging and artificial intelligence systems. 个性化黑色素瘤分级系统：一名患者的四个黑色素瘤检测超过二十年，不断发展的全身成像和人工智能系统。
Dermatology online journal Pub Date : 2024-10-15 DOI: 10.5070/D330564426
Rhett Drugge, Xhuljeta Naqo, Sabina Dedej, Galyna Girnyk, Jona Naqo, Frank Drugge, Elgida Volpicelli
{"title":"Personalized melanoma grading system: a presentation of a patient with four melanomas detected over two decades with evolving whole-body imaging and artificial intelligence systems.","authors":"Rhett Drugge, Xhuljeta Naqo, Sabina Dedej, Galyna Girnyk, Jona Naqo, Frank Drugge, Elgida Volpicelli","doi":"10.5070/D330564426","DOIUrl":"10.5070/D330564426","url":null,"abstract":"<p><p>Melanoma is a life-threatening tumor that significantly impacts individuals' health and society worldwide. Therefore, its diagnostic tools must be revolutionized, representing the most remarkable human efforts toward successful management. This retrospective study includes the multidimensional analysis of five melanomas in a man in our clinic including whole-body photography, dermatoscopy, artificial intelligence system, genetic test, and the final histopathological conclusion. The correlation between findings in each diagnostic step is discussed. The value of the melanoma grading system will be the application in high-risk lesions to make the right management decision.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous protothecosis: a new case and review of Brazilian patients. 皮肤原鞘病：巴西患者一例新病例及回顾。
Dermatology online journal Pub Date : 2024-10-15 DOI: 10.5070/D330564428
Felipe Aguinaga, Katherine Carranza, Vitoria Azulay, Olga Milena Zarco, Danielle Carvalho Quintella, Tullia Cuzzi
{"title":"Cutaneous protothecosis: a new case and review of Brazilian patients.","authors":"Felipe Aguinaga, Katherine Carranza, Vitoria Azulay, Olga Milena Zarco, Danielle Carvalho Quintella, Tullia Cuzzi","doi":"10.5070/D330564428","DOIUrl":"10.5070/D330564428","url":null,"abstract":"<p><p>Protothecosis is a rare but emerging infectious disease, caused by algae from the genus Prototheca. It presents predominantly as cutaneous lesions and poses a diagnostic challenge owing to its diverse clinical presentation. Typically, it occurs in exposed areas of the skin, associated with trauma. Diagnosis relies mainly on histopathology and culture. This article presents an elderly diabetic woman with cutaneous protothecosis from Rio de Janeiro, Brazil. We emphasize clinical features, histopathology, and successful treatment with itraconazole, along with a brief review of the 12 previously reported cases from Brazil.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bevacizumab-induced subungual hemorrhage. 贝伐珠单抗引发的真皮下出血。
Dermatology online journal Pub Date : 2024-10-15 DOI: 10.5070/D330564427
Jacob J Owen, Sloan Long, Kimberly Mullinax, John Griffin
{"title":"Bevacizumab-induced subungual hemorrhage.","authors":"Jacob J Owen, Sloan Long, Kimberly Mullinax, John Griffin","doi":"10.5070/D330564427","DOIUrl":"https://doi.org/10.5070/D330564427","url":null,"abstract":"<p><p>Exudative (wet) age-related macular degeneration can be treated with the vascular endothelial growth factor (VEGF)-inhibiting monoclonal antibody bevacizumab. Currently, bevacizumab therapy is associated with known skin-related side effects, such as rash, mucosal hemorrhage, and hemorrhagic ulcers. While subungual \"splinter\" hemorrhage is a documented side effect of VEGF receptor antagonists and Raf protein inhibitors, there are no prior reports of bevacizumab-induced subungual hemorrhage to the best of our knowledge. Thus, we present the case of a 71-year-old female diagnosed with bilateral age-related macular degeneration, who, during six months of intravitreal bevacizumab treatment, began noticing fingernail discoloration, described as similar to that of a bruise. Given our patient's history of bevacizumab therapy and the documented reports of bevacizumab-associated mucosal and ulcerative hemorrhage, we hypothesize that the discoloration and hemorrhage are likely unreported adverse effects associated with bevacizumab therapy.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Idiopathic gingival papillokeratosis with crypt formation: an exclusive entity in the young population? 伴有隐窝形成的特发性牙龈乳头角化病：年轻人群中的独有病症？
Dermatology online journal Pub Date : 2024-10-15 DOI: 10.5070/D330564431
Macarena Salinas-Munoz, Juan Aitken-Saavedra, Andrea Maturana-Ramirez
{"title":"Idiopathic gingival papillokeratosis with crypt formation: an exclusive entity in the young population?","authors":"Macarena Salinas-Munoz, Juan Aitken-Saavedra, Andrea Maturana-Ramirez","doi":"10.5070/D330564431","DOIUrl":"10.5070/D330564431","url":null,"abstract":"<p><p>Idiopathic gingival papillokeratosis with crypt formation (IGPC) is a new and a very rare benign entity, clinically characterized by white-yellowish plaques with papillary architecture located in the upper labial gingiva of adolescent patients. The condition generally exhibits a bilateral symmetrical distribution and is asymptomatic. We report two new cases, one with a classic presentation and the other in an older individual. Through these case reports, we describe and highlight the key clinical and histopathological features associated with IGPC for greater understanding and knowledge by general dentists, oral pathologists, and dermatologists.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phacomatosis spilorosea and phacomatosis melanorosea: further phenotype expansion. 外溢性和黑色性结节病：表型进一步扩大。
Dermatology online journal Pub Date : 2024-10-15 DOI: 10.5070/D330564442
Daniele Torchia
{"title":"Phacomatosis spilorosea and phacomatosis melanorosea: further phenotype expansion.","authors":"Daniele Torchia","doi":"10.5070/D330564442","DOIUrl":"https://doi.org/10.5070/D330564442","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addressing the cardiovascular implications of acanthosis nigricans: what a dermatologist needs to know. 应对黑棘皮病对心血管的影响：皮肤科医生须知。
Dermatology online journal Pub Date : 2024-10-15 DOI: 10.5070/D330564422
Evan Eggiman, Steve Feldman, Jamy Ard, Priya Patel
{"title":"Addressing the cardiovascular implications of acanthosis nigricans: what a dermatologist needs to know.","authors":"Evan Eggiman, Steve Feldman, Jamy Ard, Priya Patel","doi":"10.5070/D330564422","DOIUrl":"https://doi.org/10.5070/D330564422","url":null,"abstract":"<p><strong>Background: </strong>Acanthosis nigricans (AN) is a dermatologic skin condition that is often overlooked in its role as an indicator of underlying cardiovascular disorders. Recognizing the importance of AN beyond its cosmetic concerns is crucial for improving patient outcomes.</p><p><strong>Objective: </strong>Provide a review of AN and what every dermatologist should know of its underlying cardiovascular risk.</p><p><strong>Methods: </strong>A literature search through PubMed was performed. Terms used were \"Acanthosis Nigricans,\" \"hyperinsulinemia,\" \"cardiovascular disease,\" \"diabetes,\" \"insulin resistance,\". Further articles were found using source materials from included references. Inclusion criteria involved studies showing the association between AN and cardiovascular risks, with a specific focus on obesity and insulin resistance.</p><p><strong>Results: </strong>Acanthosis nigricans increases risks of obesity and insulin resistance as individuals with AN exhibited a 2.6-fold higher likelihood of insulin resistance, independent of other factors. Acanthosis nigricans surpassed other risk factors in classifying individuals at risk for type two diabetes and cardiovascular disease.</p><p><strong>Conclusions: </strong>Recognizing the association of AN with cardiovascular disease provides an opportunity for early intervention, focusing on weight management and underlying metabolic disorders to improve both cosmetic concerns and cardiovascular health. Dermatologists should consider AN as a signal that prompts referral for a thorough assessment for associated metabolic diseases.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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