Dermatology online journal最新文献_第6页

Blistering in a neonate: Epidermolysis bullosa or staphylococcus scalded skin syndrome? 新生儿起泡：大疱性表皮松解症还是葡萄球菌烫伤皮肤综合征？

Dermatology online journal Pub Date : 2026-05-08 DOI: 10.25251/fy4n9t79

Umi Miranti, Wahyu Ikhsan, Nadhira Hanindhiya Putri, Gargytto Rais Langlanang, Nurus Saffana Yulianto, Musdalifana Vega Ratrinda

引用次数: 0

Successful treatment of Galli-Galli Disease with dupilumab and acitretin combination therapy. 杜匹单抗和阿维素联合治疗Galli-Galli病的成功。

Dermatology online journal Pub Date : 2026-05-08 DOI: 10.25251/2wjkzs75

Matthew Reedy, Jordan Goad, Joshua Weaver

引用次数: 0

Role of dermaroller-mediated microneedling in hair follicle stimulation and hair growth. 真皮介导的微针在毛囊刺激和头发生长中的作用。

Dermatology online journal Pub Date : 2026-05-08 DOI: 10.25251/bpchfy12

Ivana T Tieu, Dora Ryan Goldstein, Kritin K Verma, Daniel P Friedmann, Michelle B Tarbox

{"title":"Role of dermaroller-mediated microneedling in hair follicle stimulation and hair growth.","authors":"Ivana T Tieu, Dora Ryan Goldstein, Kritin K Verma, Daniel P Friedmann, Michelle B Tarbox","doi":"10.25251/bpchfy12","DOIUrl":"10.25251/bpchfy12","url":null,"abstract":"Background: Dermaroller-mediated microneedling is a minimally invasive modality used to induce controlled cutaneous injury and promote hair follicle regeneration. Unlike automated microneedling devices, dermarollers are manually operated, introducing variability in technique and treatment parameters.Objective: To evaluate the efficacy, safety, and procedural variability of dermarolling as a monotherapy for hair loss.Methods: A literature search of PubMed through September 2025 was performed using terms related to dermarolling and hair loss. Studies were included if they specifically evaluated dermaroller devices. Data regarding study design, patient population, treatment parameters, and outcomes were extracted.Results: Three studies met inclusion criteria, including two human clinical studies and one animal model. One clinical study demonstrated a statistically significant increase in hair count and thickness, whereas another reported no significant improvement in hair density or scalp coverage. The animal study showed enhanced hair regeneration, with optimal effects observed at needle lengths of 0.25-0.5 mm. Considerable variability existed across studies in needle length, treatment frequency, duration, and procedural endpoints. Reported adverse effects were generally mild and transient, though improper technique may increase the risk of epidermal injury and scarring.Conclusion: Evidence supporting dermaroller monotherapy for hair loss remains limited and inconsistent. Lack of standardized protocols likely contributes to variable outcomes. Further large-scale, randomized controlled trials are needed to define optimal treatment parameters and establish the safety and efficacy of dermarollling in clinical practice.","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148600121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facial rejuvenation with autologous exosomes released from preconditioned platelet-rich plasma using the meta cell technology system: A pilot study. 利用元细胞技术系统从预处理富血小板血浆中释放的自体外泌体进行面部年轻化：一项初步研究。

Dermatology online journal Pub Date : 2026-05-08 DOI: 10.25251/b5kf0v44

Dèlia Vilà Rodríguez, Laura Cordero, Hernán Pinto

{"title":"Facial rejuvenation with autologous exosomes released from preconditioned platelet-rich plasma using the meta cell technology system: A pilot study.","authors":"Dèlia Vilà Rodríguez, Laura Cordero, Hernán Pinto","doi":"10.25251/b5kf0v44","DOIUrl":"10.25251/b5kf0v44","url":null,"abstract":"Background: Safe, noninvasive or minimally invasive techniques are available for facial rejuvenation. Recent research on exosomes has revealed promising avenues for new treatment options.Objective: This pilot study aimed to assess the efficacy of a facial rejuvenation treatment using autologous exosomes derived from preconditioned platelet-rich plasma with the Meta Cell Technology (MCT) System.Methods: A prospective, single-center, randomized, controlled pilot study was conducted in patients with facial aging signs. Participants received 3 sessions of autologous exosomes obtained using the MCT System. Outcomes were evaluated by measuring the subepidermal low-echogenic band (SLEB) using ultrasonography, capturing photographs with a compact stereophotogrammetric 3-dimensional imaging system, and obtaining patient-reported feedback on skin appearance and improvement.Results: Eleven patients (100% women; mean age, 57 ± 4.1 years; range, 51-65) were enrolled, and 9 (81.8%) completed the study. One month after the final treatment, ultrasonographic measurements demonstrated a mean reduction in SLEB thickness of 61.4% at the cheekbone and 39.35% at the cheek. Patient-reported outcomes indicated that 77.8% of participants perceived improvement in skin appearance.Conclusion: Treatment with autologous exosomes obtained using the MCT System was well tolerated and resulted in substantial facial rejuvenation, reducing SLEB thickness and enhancing patients' perceived skin quality.","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148600198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical approaches in the management of hidradenitis suppurativa: Techniques, risks, and clinical outcomes. 化脓性汗腺炎的外科治疗方法：技术、风险和临床结果。

Dermatology online journal Pub Date : 2026-05-08 DOI: 10.25251/96va0e34

Sahil Kapur, Kermanjot Sidhu, Mark Houdi, Lena Wuensch, Neha Iska, Bassem Chamma, Kritin Verma, Gabe Kleer, Craig G Burkhart

{"title":"Surgical approaches in the management of hidradenitis suppurativa: Techniques, risks, and clinical outcomes.","authors":"Sahil Kapur, Kermanjot Sidhu, Mark Houdi, Lena Wuensch, Neha Iska, Bassem Chamma, Kritin Verma, Gabe Kleer, Craig G Burkhart","doi":"10.25251/96va0e34","DOIUrl":"10.25251/96va0e34","url":null,"abstract":"Background: Hidradenitis suppurativa (HS) is a chronic, progressive, inflammatory dermatologic condition that affects intertriginous areas with high concentrations of apocrine glands. Initial management is medical; however, surgical excision and wound reconstruction are indicated for severe or refractory disease. This study evaluated current surgical techniques for HS and analyzed their associated risks and reported outcomes.Methods: A review of the literature was conducted to assess surgical approaches, including incision and drainage, deroofing, local excision, wide excision, cryoinsufflation, and laser therapies. Reported complication and recurrence rates were analyzed.Results: Wide excision is favored over less extensive techniques for Hurley stage II and III HS, with lower recurrence and complication rates. The estimated overall complication rate for surgical treatment is 11.1% (95% confidence interval [CI], 6.4%-16.9%), and the estimated overall recurrence rate is 16.2% (95% CI, 9.1%-24.9%).Conclusion: These findings support a more aggressive surgical approach when minimizing recurrence is a primary goal. Procedure selection should be individualized based on patient lifestyle, comorbidities, disease location, and long-term efficacy. Further rigorous research into emerging multidisciplinary therapies and surgical innovations is needed to establish an improved standard of care for HS.","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148600166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on: Frequency of statistical mistakes and associated article characteristics: A cross-sectional analysis of dermatology journals. 点评：统计错误的频率和相关的文章特征：皮肤病学期刊的横断面分析。

Dermatology online journal Pub Date : 2026-05-08 DOI: 10.25251/fgc2ph98

Richard Laven, D Aaron Yang

引用次数: 0

The efficacy and safety of interleukin-17 and interleukin-23 inhibitors in psoriatic arthritis across multiple disease domains. 白介素-17和白介素-23抑制剂治疗银屑病关节炎的疗效和安全性

Dermatology online journal Pub Date : 2026-05-08 DOI: 10.25251/zsav4a48

Danny Zakria, Milaan Shah, Angela Rosenberg, Joshua Burshtein, Lauren DeBusk, David A Altman, April W Armstrong, Alice B Gottlieb, George Han, Saakshi Khattri, Sheila Shaigany, Jeffrey M Weinberg, Mark Lebwohl

{"title":"The efficacy and safety of interleukin-17 and interleukin-23 inhibitors in psoriatic arthritis across multiple disease domains.","authors":"Danny Zakria, Milaan Shah, Angela Rosenberg, Joshua Burshtein, Lauren DeBusk, David A Altman, April W Armstrong, Alice B Gottlieb, George Han, Saakshi Khattri, Sheila Shaigany, Jeffrey M Weinberg, Mark Lebwohl","doi":"10.25251/zsav4a48","DOIUrl":"10.25251/zsav4a48","url":null,"abstract":"Background: Psoriatic arthritis (PsA) is a heterogeneous, immune-mediated inflammatory disease affecting peripheral joints, entheses, skin, and nails. Despite multiple available biologic therapies, unmet needs persist, particularly in patients with multisystem involvement or prior biologic failure. Interleukin (IL)-17 and IL-23 pathway inhibitors are widely used in PsA; however, important differences exist in their clinical efficacy across disease domains.Methods: A comprehensive literature review was conducted using PubMed, Scopus, and Google Scholar to identify randomized controlled trials, long-term extension studies, mechanistic studies, and meta-analyses evaluating IL-17 and IL-23 inhibitors in PsA and related spondyloarthritides. A multidisciplinary panel of expert dermatologists and rheumatologists convened for a structured roundtable discussion. A modified Delphi process was used to develop and approve consensus statements. Strength of Recommendation Taxonomy (SORT) criteria were applied to each statement.Results: Eight consensus statements were unanimously adopted. These statements address radiographic progression, axial disease, mechanistic considerations of IL-17A and IL-17F inhibition, comparative efficacy of bimekizumab, treatment sequencing, and safety considerations, including candidiasis, hepatic effects, and psychiatric outcomes.Conclusion: Based on the totality of available evidence, IL-17 inhibitors play an important role in the management of PsA across multiple disease domains. Differences between IL-17 and IL-23 pathway inhibition have important implications for treatment selection, particularly in patients with axial disease, significant skin involvement, or prior biologic failure.","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148600185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association or coincidence: Leishmania and sporotrichosis. 关联或巧合：利什曼原虫和孢子虫病。

Dermatology online journal Pub Date : 2026-05-08 DOI: 10.25251/5pwjsg51

Stephany Arias Linthon, Valeria Sofia Soto Ariño, Hugo Eduardo Herrera Nossa, Mariam Rolón Cadena, Sebastian Ramiro Gil-Quiñones

引用次数: 0

Primary care engagement in hidradenitis suppurativa: Influence of disease severity, cardiometabolic risk, and access barriers. 化脓性汗腺炎的初级保健参与：疾病严重程度、心脏代谢风险和获取障碍的影响

Dermatology online journal Pub Date : 2026-05-08 DOI: 10.25251/jc8msv36

Charlotte McRae, Sivani B Reddy, Michael Anderson, Laci Turner, Tiffany Mayo

{"title":"Primary care engagement in hidradenitis suppurativa: Influence of disease severity, cardiometabolic risk, and access barriers.","authors":"Charlotte McRae, Sivani B Reddy, Michael Anderson, Laci Turner, Tiffany Mayo","doi":"10.25251/jc8msv36","DOIUrl":"10.25251/jc8msv36","url":null,"abstract":"Background: Hidradenitis suppurativa (HS) is linked to cardiometabolic disease (CMD), and guidelines recommend annual primary care visits. This study examined predictors of primary care utilization among patients with HS.Methods: In this cross-sectional study, 307 patients with HS were analyzed. χ2 tests, one-way analysis of variance, and multivariable logistic regression assessed associations among barriers to care, primary care provider (PCP) adherence, HS severity, and CMD presence.Results: Mean age was 39.4 years; 26.4% had Hurley stage III disease. Overall PCP adherence was 85.0% but lower in patients under 30 years (71.0%). CMD prevalence included hypertension (33.9%), type 2 diabetes (17.6%), and hypercholesterolemia (32.9%). Patients without CMD were 74.0% less likely to adhere to annual PCP visits (adjusted odds ratio [AOR], 0.26; P = .001), and being uninsured reduced adherence by 82.0% (AOR, 0.18; P = .01). HS severity did not predict adherence, but Hurley stage III disease was associated with more PCP visits and independently predicted type 2 diabetes (AOR, 2.26; P = .02).Conclusion: Primary care engagement is influenced more by CMD and insurance than HS severity. Coordinated dermatology-primary care strategies may enhance preventive care, especially for younger patients without CMD.","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148600196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cystic panfolliculoma of the conchal bowl. 气管碗囊性全滤泡瘤。

Dermatology online journal Pub Date : 2026-03-02 DOI: 10.25251/0d92fd02

John Monroe, Lindsey J Gaghan, John Kawaoka, Leslie Robinson Bostom

引用次数: 0