Dermatology online journal最新文献_第4页

A case of trastuzumab-deruxtecan-induced subacute cutaneous lupus erythematous. 曲妥珠单抗-德鲁西替康致亚急性皮肤红斑狼疮1例。

Dermatology online journal Pub Date : 2025-04-15 DOI: 10.5070/D331265294

Nicole Trepanowski, Payal Shah, Heidi Bai, Shaofeng Yan, Natalie Fragoso, Dorothea Barton

{"title":"A case of trastuzumab-deruxtecan-induced subacute cutaneous lupus erythematous.","authors":"Nicole Trepanowski, Payal Shah, Heidi Bai, Shaofeng Yan, Natalie Fragoso, Dorothea Barton","doi":"10.5070/D331265294","DOIUrl":"https://doi.org/10.5070/D331265294","url":null,"abstract":"Drug-induced subacute cutaneous lupus erythematosus (DI-SCLE) is an erythematous, photodistributed, scaly, and annular cutaneous eruption that is clinically similar to subacute cutaneous lupus erythematosus. However, DI-SCLE is associated with medication use and generally resolves or greatly improves following discontinuation. Chemotherapeutic agents are common triggers of DI-SCLE. We report a patient with breast cancer who experienced multiple episodes of DI-SCLE associated with the use of different chemotherapeutic agents for treatment-resistant cancer. Notably, to the best of our knowledge, this case highlights the first reported association of DI-SCLE with trastuzumab deruxtecan. Additionally, this case is unique owing to a component of radiation recall dermatitis, as the rash was prominent in areas that had prior ionizing radiation. A prior history of DI-SCLE in oncology patients who continue to undergo treatment should prompt clinicians to consider DI-SCLE when faced with a new photodistributed, erythematous, annular, and scaly eruption. Early initiation of immunomodulating agents like hydroxychloroquine in patients with a history of moderate to severe DI-SCLE to chemotherapy who continue to undergo anti-cancer treatment may provide benefit and warrants further investigation.","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145136824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clarifying the role of skin tension lines in dermatological surgery. 阐明皮肤张力线在皮肤外科手术中的作用。

Dermatology online journal Pub Date : 2025-04-15 DOI: 10.5070/D331265288

Erin R Pomerantz, Nicole L Griffin, Nicholas D Brownstone

引用次数: 0

Pearls for dermatology resident education in cosmetic and laser procedures. 用于皮肤科住院医师美容和激光手术教育的珍珠。

Dermatology online journal Pub Date : 2025-04-15 DOI: 10.5070/D331265287

Alexandra Richmond, Lucia Ray, Kevin Truong-Balderas, Rawaa Almukhtar, Kira Minkis, Milad Eshaq, Travis Kuemmet, Jayne S Joo, Shraddha Desai, Roberta Lucas, Carlos Wambier, Alison Boucher, Bianca Kang, Yakir Levin, Saranya Wyles, Murad Alam

{"title":"Pearls for dermatology resident education in cosmetic and laser procedures.","authors":"Alexandra Richmond, Lucia Ray, Kevin Truong-Balderas, Rawaa Almukhtar, Kira Minkis, Milad Eshaq, Travis Kuemmet, Jayne S Joo, Shraddha Desai, Roberta Lucas, Carlos Wambier, Alison Boucher, Bianca Kang, Yakir Levin, Saranya Wyles, Murad Alam","doi":"10.5070/D331265287","DOIUrl":"https://doi.org/10.5070/D331265287","url":null,"abstract":"Comprehensive education in cosmetic and laser procedures is fundamental during dermatology residency to meet the demand for cosmetic medical procedures and effectively treat a myriad of complex dermatological conditions. This article highlights the importance of structured learning to provide step-wise opportunities for proficiency throughout residency. Although reading assignments and didactic sessions create a solid foundation, focused workshops, resident cosmetic clinics, and offsite electives serve as important experiences for residents to practice hands-on skills. This article provides guidance for curriculum development and establishing hands-on procedural learning. Additionally, the importance of joining professional societies to receive unique training as well as mentorship is highlighted. Having a structured and comprehensive cosmetic curriculum will equip dermatology residents with the toolkit to successfully care for diverse patient needs effectively and safely.","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145136705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple bluish papules and nodules in a 12-year-old child with lower gastrointestinal bleeding: a diagnostic challenge. 多发蓝色丘疹和结节12岁儿童下消化道出血：一个诊断挑战。

Dermatology online journal Pub Date : 2025-04-15 DOI: 10.5070/D331265296

Claudia Brazao, Dora Mancha, Lanyu Sun, Sofia Antunes-Duarte, Sonia Fernandes, Luis Rodrigues, Marcia Rodrigues, Pedro De Vasconcelos, Luis Soares-de-Almeida, Paulo Filipe

引用次数: 0

Deconstructing the prevalence of undifferentiated pleomorphic sarcoma across socio-demographic groups: a potential launchpad for future research. 解构未分化多形性肉瘤在社会人口统计学群体中的患病率：未来研究的潜在启动平台。

Dermatology online journal Pub Date : 2025-04-15 DOI: 10.5070/D331265306

Shangyi Fu, Matthew Taing, Danny Huynh, Brett Keeling, Ammar Ahmed

引用次数: 0

Styling practices, crown thinning, and scalp health in Black women. 黑人女性的造型实践、头冠稀疏和头皮健康。

Dermatology online journal Pub Date : 2025-04-15 DOI: 10.5070/D331265305

Josephine Pyles, Chrislene Olukoga, Nidhi Avashia-Khemka

引用次数: 0

Foreign body granuloma from retained temporary epicardial pacing wire disguised as a painful, nonhealing cutaneous nodule. 残留的临时心外膜起搏导线形成的异物肉芽肿，伪装成疼痛的、无法愈合的皮肤结节。

Dermatology online journal Pub Date : 2025-04-15 DOI: 10.5070/D331265298

Madelyn Class, Bansri M Patel, Kentaro Yamane, Kimberly M Ken

{"title":"Foreign body granuloma from retained temporary epicardial pacing wire disguised as a painful, nonhealing cutaneous nodule.","authors":"Madelyn Class, Bansri M Patel, Kentaro Yamane, Kimberly M Ken","doi":"10.5070/D331265298","DOIUrl":"https://doi.org/10.5070/D331265298","url":null,"abstract":"A 76-year-old woman with a significant cardiac surgery and breast cancer history presented to the dermatology clinic with a three-year history of an enlarging, tender, nonhealing cutaneous nodule on her upper abdomen. A shave biopsy was attempted given concern for nonmelanoma skin cancer or cutaneous metastasis. The biopsy was halted after a white wire was visualized. Retrospective computed tomography (CT) imaging review revealed a hyperdense linear structure becoming superficial at the location of the nodule seen on examination. Discussion with a cardiothoracic surgeon revealed this wire was likely a retained temporary epicardial pacing wire that was placed at the time of the patient's cardiac surgery three years prior. The decision was made to excise the lesion to fully remove the wire. Given intraoperative resistance with traction, the wire was partially removed by cutting it flush to the skin's surface. The patient healed appropriately with complete resolution of her symptoms. This case is unique because the wire was fully visualized on the CT scan, and it was unable to be fully removed.","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145136770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secondary anetoderma following lichen planus. 扁平地衣后继发无性皮病。

Dermatology online journal Pub Date : 2025-04-15 DOI: 10.5070/D331265295

Alex Y Liu, Luis J Borda, Robert J Pariser

引用次数: 0

Erlotinib-induced trichomegaly of eyelashes in lung cancer treatment: Epidermal growth factor receptor inhibitor side effect. 厄洛替尼诱导的肺癌治疗中睫毛毛脱落：表皮生长因子受体抑制剂的副作用。

Dermatology online journal Pub Date : 2025-04-15 DOI: 10.5070/D331265292

Meriem El Haddad, Ouiame El Jouari, Gallouj Salim

{"title":"Erlotinib-induced trichomegaly of eyelashes in lung cancer treatment: Epidermal growth factor receptor inhibitor side effect.","authors":"Meriem El Haddad, Ouiame El Jouari, Gallouj Salim","doi":"10.5070/D331265292","DOIUrl":"https://doi.org/10.5070/D331265292","url":null,"abstract":"Erlotinib is one of the epithelial growth factor receptor tyrosine kinase inhibitors that have been developed and extensively employed in the treatment of non-small cell lung cancer, particularly in individuals with activating epithelial growth factor receptor mutations. This report presents a case of erlotinib induced eyelash trichomegaly and irritation, a rare side effect in a woman who received erlotinib for lung adenocarcinoma. Following the detection of an epithelial growth factor receptor mutation in tumor tissue from a non-small cell lung cancer in a nonsmoking woman, the patient was initiated on erlotinib therapy. After several months, she experienced significant overgrowth of both eyelashes, leading to vision problems. Dermoscopy findings revealed an increase in the length and thickness of the eyelashes associated with inflammation of the eyelid's edges. It has been hypothesized that the inhibition of epithelial growth factor receptor signaling by epithelial growth factor receptor tyrosine kinase inhibitors could alter the growth pattern of hair, potentially leading to the induction of abnormal hair growth, such as trichomegaly, which has been reported only in a small number of case reports.","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145136647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutaneous metastasis of serous ovarian carcinoma. 浆液性卵巢癌的皮肤转移。

Dermatology online journal Pub Date : 2025-04-15 DOI: 10.5070/D331265293

Jessica Padniewski, Ilhan Esse, Andrew Truong, Kevin Gaddis

引用次数: 0