Current pediatrics最新文献

{"title":"Aortic Isthmus Retrograde Blood Flow in Intrauterine Child as a Sign of the Terminal Stage of Placental Dysfunction: Clinical Observation","authors":"N. M. Normuradova","doi":"10.15690/vsp.v22i2.2537","DOIUrl":"https://doi.org/10.15690/vsp.v22i2.2537","url":null,"abstract":"Background. Aortic isthmus retrograde blood flow in intrauterine children with growth delay and centralization of blood circulation in the late stages of placental dysfunction is associated with a high risk of perinatal death. Timely diagnosis of such condition is crucial to select further obstetric tactics and delivery time. Clinical case description. Growth delay and absent end-diastolic flow in umbilical artery and no A-wave in the venous duct were diagnosed in intrauterine child (gestational age — 36 weeks) at ultrasound study. Peripheral resistance indices in middle cerebral artery in the intrauterine child were lower than peripheral resistance indices in umbilical artery. Color Doppler imaging has revealed aortic isthmus retrograde blood flow. The woman was recommended delivery due to critical circulatory disorder in the intrauterine child. Female child was delivered via Caesarean section, child’s weight — 890 g, APGAR score — 3/4. The newborn girl died due to multi-organ failure within the first day.Conclusion. Revealing the retrograde blood flow in intrauterine child in the aortic isthmus throughout the entire ventricular diastole is an unfavorable prognostic sign of the terminal stage of cerebral blood flow disturbance associated with placental dysfunction.","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78608556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in the Preventive Vaccination Procedures in Children’s City Outpatient’s Clinic and its Efficacy","authors":"Snezhana D. Timoshkova, D. Rusinova, Tatyana N. Elagina, G. Glazkova, M. Fedoseenko, L. Namazova-Baranova","doi":"10.15690/vsp.v22i2.2563","DOIUrl":"https://doi.org/10.15690/vsp.v22i2.2563","url":null,"abstract":"This article describes the implementation stages of the changes in preventive vaccination procedures in Children’s City Outpatient’s Clinic №133 of the Moscow Department of Health since December 2019. Comprehensive work has been performed on increasing the adherence to vaccination among doctors of various specialties, vaccination and immunization coverage of the registered pediatric population. As a result of this project medical prevention department was reorganized, data on vaccinations, medical exemption and refusals were added to the electronic medical records, monthly monitoring of vaccination coverage rate was initiated, as well as doctors training in preventive immunization via three forms of education. Center for Medical Prevention of the Moscow Department of Health, pediatric department of the Pediatric Faculty of Pirogov Russian National Research Medical University, the Union of Pediatricians of Russia have participated in this work. Intermediate results on efficacy of implemented measures have been presented.","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74104040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analgesia and Sedation in Newborns with Long-Term Mechanical Ventilation","authors":"E. V. Shestak, O. Kovtun","doi":"10.15690/vsp.v22i2.2536","DOIUrl":"https://doi.org/10.15690/vsp.v22i2.2536","url":null,"abstract":"Relevant data on drugs used for analgesia and sedation in newborns in the intensive care units during mechanical ventilation is presented. The overview of studies on the most common sedatives and analgesics (opioids, acetaminophen, ketamine, midazolam, dexmedetomidine, propofol) is provided. Analysis of their efficacy and risk of short-term and long-term adverse effects is presented, including those associated with the child’s nervous system development. The use of drugs both as monotherapy and in combination with other medications for analgesia and sedation is being discussed.","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76412367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic Diarrhea as a Debut Manifestation of Crohn’s Disease in Infant: Clinical Case","authors":"Anna M. Konovalova, D. V. Pechkurov, A. Tyazheva","doi":"10.15690/vsp.v22i1.2518","DOIUrl":"https://doi.org/10.15690/vsp.v22i1.2518","url":null,"abstract":"Background. Chronic diarrhea can be a symptom of a wide variety of diseases, either of which requires special therapy approaches. The diagnosis of rare causes of chronic diarrhea is especially difficulty as it may be associated with inflammatory bowel disease (IBD) with very early (under 1 year of age) debut.Clinical case description. Boy E. had chronic diarrhea manifested on the first year of life. Ulcerative colitis was diagnosed at the age of 1.5 years, then the diagnosis was changed to Crohn’s disease at the age of 2.5 years. The results of 6-years-follow-up of the patient were presented, as well as analysis of diagnosis and treatment difficulties was carried out.Conclusion. The clinical case of Crohn’s disease with diarrhea as the leading clinical manifestation at the disease onset is described. Sequential diagnostic search allowed us to establish the diagnosis of IBD and to exclude other causes of chronic diarrhea that determined the correct therapeutic strategy. ","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90058325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Diagnostic Significance of Herpes Virus Infections’ Serological Markers in Children: Overdiagnosis or Clinically Relevant Studies? Retrospective Study","authors":"A. Ivanov, T. Kulichenko","doi":"10.15690/vsp.v22i1.2519","DOIUrl":"https://doi.org/10.15690/vsp.v22i1.2519","url":null,"abstract":"Background. Nowadays, population generally has high contamination with herpes virus infections. Infection commonly is asymptomatic, and the virus persists in the human body over a lifetime. Excessive diagnosis of herpes virus infections as well as overestimation of their role in the genesis of various diseases in immunocompetent people are common in Russian pediatrics.Objective. The aim of the study is to assess the frequency and efficacy of serological testing in the suspected correlation of herpes virus infections and infectious and somatic diseases in a multidisciplinary hospital.Methods. The study included patients hospitalized in the multidisciplinary hospital in Moscow, who were assigned serological examination for herpes viruses. The laboratory study was carried out by enzyme-linked immunosorbent assay with the revealing the markers of herpes simplex virus type 1 and 2, Epstein-Barr virus, and cytomegalovirus. The results of the examination were analyzed according to the nosology and their role in diagnosis and management.Results. The identification of herpes virus infections’ markers was performed for 996 patients undergoing medical treatment in 17 different hospital departments within 2 months. Most commonly the examination was prescribed in infectious disease, pediatric, and hematological departments and covered more than 140 different nosologies. Acute respiratory infection, reactive arthritis, thrombocytopenia, infectious mononucleosis, acute tonsillitis, gastrointestinal pathology, acute bronchitis, and pneumonia were the most common nosologies. Positive markers of acute infection were revealed in 1.71% of cases for HSV-1/HSV-2, in 4.89% — for EBV, in 3.81% — for CMV. Moreover, positive results of serological examination were mostly noted in the cases of infectious diseases: infectious mononucleosis, tonsillitis, or acute respiratory infections. Tests were assigned for all three infections at the same time in most cases.Conclusion. Widespread examination for herpes virus infections is the typical variant of overdiagnosis and it is usually less informative. Generally positive markers are observed in typical course of herpes virus infections when clinical picture is enough for diagnosis verification. ","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84441070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Langerhans Cell Histiocytosis in Children: Literature Review","authors":"Evgeniy A. Burtsev, G. Bronin","doi":"10.15690/vsp.v22i1.2520","DOIUrl":"https://doi.org/10.15690/vsp.v22i1.2520","url":null,"abstract":"Relevant information on Langerhans cell histiocytosis development and course in children is presented. The current concepts of disease pathogenesis, principles of its severity evaluation, patients stratification into risk groups, as well as of clinical course features are described. Modern approaches to the disease treatment via targeted therapy are summarized and analyzed. ","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86334048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Anthropometric Data of Children Died at Perinatal Period","authors":"K. Moiseeva, D. Ivanov, V. K. Yur'ev, E. Berezkina, Kseniya G. Shevtsova, A. V. Alekseeva, Sh. Kharbedia","doi":"10.15690/vsp.v22i1.2516","DOIUrl":"https://doi.org/10.15690/vsp.v22i1.2516","url":null,"abstract":"Background. Despite the decrease in fetoinfantile losses, the levels of perinatal mortality and stillbirth remain quite high. One of the medical criteria for viability is the anthropometric indicators of the child, therefore, their relevant medical and statistical assessment may allow us to establish potential opportunities for reducing the loss of viable children at perinatal period.Objective. The aim of the study is to assess anthropometric data of children died at perinatal period.Methods. We have analyzed 277 cases of children deaths at ante- and intranatal periods and 197 cases of newborns deaths during first 7 days of life. Assessment of anthropometric data of children died at perinatal period was presented via the method of sigmal deviations and the centile method.Results. Anthropometric data of premature infants died at perinatal period in 90–94% of cases corresponded to the physical development for children of this gestational age. Anthropometric data of full-term children died during the first 168 hours of life, in 70.0% of cases, corresponded to 3–6 corridors of physical development (P10–P90), in 20.0% of cases — 7–8 corridors. 58.3% of full-term children died at perinatal period have harmonious development which significantly exceeds the proportion of children with sharply disharmonious development (19.5%) and with disharmonious development (22.2%). 79.0% of all neonatal deaths occur in the first 72 hours of life (for the early neonatal period), while losses on the first day account for 54.0% of all deaths in children during the first week.Conclusion. This study has shown that the anthropometric data of children died at perinatal period significantly corresponded to the standard indicators established for children of this gestation age. ","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86615972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"G.N. Speransky’s Contribution to the Development of Russian Pediatrics (to the 150th Anniversary of His Birth)","authors":"A. Baranov, S. A. Sher","doi":"10.15690/vsp.v22i1.2532","DOIUrl":"https://doi.org/10.15690/vsp.v22i1.2532","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87145591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organization of Medical Care for Children in Home Front and on Front-Line Territories during the Great Patriotic War","authors":"O. Yaremchuk, R. S. Serebryaniy, D. V. Kamelskikh","doi":"10.15690/vsp.v22i1.2528","DOIUrl":"https://doi.org/10.15690/vsp.v22i1.2528","url":null,"abstract":"The status of open and closed children’s institutions (nurseries, orphanages), existing personnel potential, results of communicablediseases control in Yamal (home front territory) and in Kuibyshev region (front-line territory) were analyzed. The differences in primary problems solving by Yamal and the Kuibyshev Region health authorities stood out. The key issues in Yamalo-Nenets national district were prevention of mass diseases and combating highly infectious diseases (typhus, etc.). Meanwhile, the key aspect of medical care in Kuibyshev region was to implement measures to combat the spread of gastrointestinal tract diseases and digestive disorders. Data is provided to compare the nutrition status of children in Arctic region and in Middle Volga region using these two regions’ examples. Difficulties in food supply are shown. They were quite the same despite the difference in habitat and the contingent of children (evacuated from Kuibyshev region and tundra residents). The claim that Yamal was supplied with food and industrial products with higher standards than southern regions has been questioned as archival documents have revealed the insufficient availability of products in children’s institutions ","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79151763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital Knee Dislocation: Help for Neonatologists and Pediatricians","authors":"I. Y. Kruglov, N. Y. Rumyantsev, G. G. Omarov, N. N. Rumyantseva, I. Kagantsov","doi":"10.15690/vsp.v22i1.2517","DOIUrl":"https://doi.org/10.15690/vsp.v22i1.2517","url":null,"abstract":"Congenital knee dislocation is relatively rare pathology of the musculoskeletal system. Timely diagnosis and treatment onset allow us to achieve full range of motion in the knee joint. However, low awareness of physicians in these topics and, as a result, diagnostic errors lead to pseudo-correction and motor deficit in the knee joint. This article describes correct examination of a child with congenital knee dislocation directly in the delivery room, management after discharge, and subsequent patient's routing with the assistance of orthopedic traumatologist.","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74796226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}