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Klassiker des deutschsprachigen Dokumentarfilms Pub Date : 1900-01-01 DOI: 10.5771/9783741001109-35
Thomas Bräutigam
{"title":"A","authors":"Thomas Bräutigam","doi":"10.5771/9783741001109-35","DOIUrl":"https://doi.org/10.5771/9783741001109-35","url":null,"abstract":"A spontaneous murine metastatic tumor system was used as a model to assess the effects of a major surgical procedure on tumor-specific immune reactivity and the growth of micrornetastases. Any major surgical procedure resulted in impaired cell-mediated cytotoxicity postoperatively and an increase in the number of gross pulmonary metastases. The use of an immunorestorative drug, Thiabendazole, in the perioperative period resulted in an improved cytotoxic response and a significant decrease in pulmonary metastases. Perioperative immunotherapy can be an effective adjunct to surgery in preventing the growth of micrometastatic foci","PeriodicalId":108632,"journal":{"name":"Klassiker des deutschsprachigen Dokumentarfilms","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131446175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Titelei/Inhaltsverzeichnis Titelei /目录。
Klassiker des deutschsprachigen Dokumentarfilms Pub Date : 1900-01-01 DOI: 10.5771/9783741001109-1
Thomas Bräutigam
{"title":"Titelei/Inhaltsverzeichnis","authors":"Thomas Bräutigam","doi":"10.5771/9783741001109-1","DOIUrl":"https://doi.org/10.5771/9783741001109-1","url":null,"abstract":"","PeriodicalId":108632,"journal":{"name":"Klassiker des deutschsprachigen Dokumentarfilms","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124830269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biografische Notizen Biografische笔记
Klassiker des deutschsprachigen Dokumentarfilms Pub Date : 1900-01-01 DOI: 10.3726/978-3-653-02883-6/8
Thomas Bräutigam
{"title":"Biografische Notizen","authors":"Thomas Bräutigam","doi":"10.3726/978-3-653-02883-6/8","DOIUrl":"https://doi.org/10.3726/978-3-653-02883-6/8","url":null,"abstract":"","PeriodicalId":108632,"journal":{"name":"Klassiker des deutschsprachigen Dokumentarfilms","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132796706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
G G
Klassiker des deutschsprachigen Dokumentarfilms Pub Date : 1900-01-01 DOI: 10.5771/9783741001109-92
Thomas Bräutigam
{"title":"G","authors":"Thomas Bräutigam","doi":"10.5771/9783741001109-92","DOIUrl":"https://doi.org/10.5771/9783741001109-92","url":null,"abstract":"","PeriodicalId":108632,"journal":{"name":"Klassiker des deutschsprachigen Dokumentarfilms","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133529052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personenregister Personenregister
Klassiker des deutschsprachigen Dokumentarfilms Pub Date : 1900-01-01 DOI: 10.5771/9783741001109-313
Thomas Bräutigam
{"title":"Personenregister","authors":"Thomas Bräutigam","doi":"10.5771/9783741001109-313","DOIUrl":"https://doi.org/10.5771/9783741001109-313","url":null,"abstract":"","PeriodicalId":108632,"journal":{"name":"Klassiker des deutschsprachigen Dokumentarfilms","volume":"215 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132947793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
L l
Klassiker des deutschsprachigen Dokumentarfilms Pub Date : 1900-01-01 DOI: 10.5771/9783741001109-133
Thomas Bräutigam
{"title":"L","authors":"Thomas Bräutigam","doi":"10.5771/9783741001109-133","DOIUrl":"https://doi.org/10.5771/9783741001109-133","url":null,"abstract":". We prove a non-vanishing result of modular L -values with quadratic twists, where the quadratic discriminants are in a short interval. Us- ing this fact and Waldspurger’s theorem, we improve the results of Balog-Ono[The chebotarev density theorem in short intervals and some questions of Serre, Journal of number theory. 91(2):356-371(2001)] on the non-vanishing of Fourier coefficients of half-integral weight eigenform.","PeriodicalId":108632,"journal":{"name":"Klassiker des deutschsprachigen Dokumentarfilms","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116031541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
N N
Klassiker des deutschsprachigen Dokumentarfilms Pub Date : 1900-01-01 DOI: 10.5771/9783741001109-169
Thomas Bräutigam
{"title":"N","authors":"Thomas Bräutigam","doi":"10.5771/9783741001109-169","DOIUrl":"https://doi.org/10.5771/9783741001109-169","url":null,"abstract":"","PeriodicalId":108632,"journal":{"name":"Klassiker des deutschsprachigen Dokumentarfilms","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116032711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
O O
Klassiker des deutschsprachigen Dokumentarfilms Pub Date : 1900-01-01 DOI: 10.5771/9783741001109-182
Thomas Bräutigam
{"title":"O","authors":"Thomas Bräutigam","doi":"10.5771/9783741001109-182","DOIUrl":"https://doi.org/10.5771/9783741001109-182","url":null,"abstract":"","PeriodicalId":108632,"journal":{"name":"Klassiker des deutschsprachigen Dokumentarfilms","volume":"61 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117223720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P P
Klassiker des deutschsprachigen Dokumentarfilms Pub Date : 1900-01-01 DOI: 10.5771/9783741001109-186
Thomas Bräutigam
{"title":"P","authors":"Thomas Bräutigam","doi":"10.5771/9783741001109-186","DOIUrl":"https://doi.org/10.5771/9783741001109-186","url":null,"abstract":"Genomic profiling of pancreatic cancer using small core biopsies has taken an increasingly prominent role in precision medicine. However, if not appropriately preserved, nucleic acids (NA) from pancreatic tissues are known to be susceptible to degradation due to high intrinsic levels of nucleases. PAXgene fixation (PreAnalytix, Switzerland) represents a novel formalin-free tissue preservation method. We sought to compare the NA and histomorphological preservation of pancreatic cancer tissues preserved with PAXgene-fixed paraffin-embedding (PFPE) and formalinfixed paraffin-embedding (FFPE). Tissues from 19 patients were obtained prospectively from pancreaticoduodenectomy specimens and evaluated by four gastrointestinal pathologists. The extracted NA were quantified by Nanodrop and Qubit and assessed for quality by qPCR, targeted next-generation sequencing (NGS) assay, and RNA-sequencing. Our results demonstrated that, when assessed blindly for morphological quality, the four pathologists deemed the PFPE slides adequate for diagnostic purposes. PFPE tissues enable greater yields of less fragmented and more amplifiable DNA. PFPE tissues demonstrated significantly improved quality control (QC) metrics in a targeted NGS assay including Median Absolute Pair-wise Difference (MAPD) scores. Our results support the use of PAXgene fixative for the processing of specimens from pancreatic cancers with the potential benefits of improved yields for more amplifiable DNA in low-yield biopsy specimens and its ideal use for amplicon-based NGS assays.","PeriodicalId":108632,"journal":{"name":"Klassiker des deutschsprachigen Dokumentarfilms","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121754393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
H H
Klassiker des deutschsprachigen Dokumentarfilms Pub Date : 1900-01-01 DOI: 10.5771/9783741001109-100
Thomas Bräutigam
{"title":"H","authors":"Thomas Bräutigam","doi":"10.5771/9783741001109-100","DOIUrl":"https://doi.org/10.5771/9783741001109-100","url":null,"abstract":"","PeriodicalId":108632,"journal":{"name":"Klassiker des deutschsprachigen Dokumentarfilms","volume":"791 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131827410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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