Current opinion in dentistry最新文献

{"title":"Molecular Diagnosis of Fibro-osseous Lesions of the Oral and Maxillofacial Region: A Tale from Africa","authors":"O. Soyele, A. H. Adedapo, H. Adeola","doi":"10.2174/2542579X01666180613075855","DOIUrl":"https://doi.org/10.2174/2542579X01666180613075855","url":null,"abstract":"\u0000\u0000Fibro-osseous lesions (FOLs) are a poorly defined but pathologically diverse group of lesions\u0000affecting the craniofacial bones and jaw. They are mostly characterized by the replacement of\u0000bone by a benign connective tissue matrix, which may contain foci of mineralization in the form of\u0000woven bone or cementum-like round acellular intensely basophilic structures. These lesions, although\u0000diverse, often present similar clinico-pathological and radiographic features. This often leads\u0000to difficulty in diagnosis and management. Definitive diagnosis is often reached only by incisional\u0000or excisional biopsy in resource-limited settings. Epidemiologically, the incidence and prevalence of\u0000different FOLs have been variable depending on the region. Reports from Africa indicated that\u0000FOLs make up to 10% of all oral biopsies, while others have given lower figures. A good understanding\u0000of the pathogenetic mechanism for FOLs is important, and state of the art molecular approaches\u0000are bound to improve the diagnosis and delineation of various entities that fall under the\u0000FOL category. Not least, the classification and nomenclature of these lesions by the World Health\u0000Organization (WHO) have changed significantly over the years. Hence, we have presented in this\u0000review a robust discussion on the pathobiology, emerging molecular markers, diagnostic challenges,\u0000future perspectives and recent changes to the classification/nomenclature of FOLs by WHO. In addition,\u0000we also discussed the diagnostic bottlenecks encountered during diagnosis of FOL in Africa.\u0000","PeriodicalId":10853,"journal":{"name":"Current opinion in dentistry","volume":"155 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77404184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platelet Concentrates in Oral Surgery: Indications and Limits. A Literature Review","authors":"G. Marenzi, Med Erda Qorri, P. Sammartino, F. Rusciano, R. Gasparro","doi":"10.2174/2542579x01666180621154507","DOIUrl":"https://doi.org/10.2174/2542579x01666180621154507","url":null,"abstract":"\u0000\u0000Background: Platelet concentrates (PC) are blood-derived products for local application\u0000able to stimulate regeneration in soft and hard tissues, mimicking the physiological healing process.\u0000Their efficacy in oral surgical procedures is controversial and limited.\u0000\u0000Objective: The study aims to critically analyze the available evidence for the effect of autogenous\u0000PC on wound healing of different oral surgical sites reported by more recent clinical studies.\u0000\u0000Methods: Electronic and manual searches in three databases (Medline, Web of Science, Scopus)\u0000were performed to identify the clinical studies from January 2017 to December 2017 which reported\u0000the actual oral surgical indications and the benefit of local application of PC. All human studies\u0000evaluating PRP or PRF in a randomized controlled trial, case series, case report and systematic review\u0000were included. All animal, histologic and in vitro studies were excluded.\u0000\u0000Results: Fifty-two studies were selected. The use of PRF was proposed in treating many oral surgical\u0000sites. Data availability with regard to the effect of PRF on new bone formation in GBR and horizontal/\u0000vertical bone augmentation procedures varied from abundant to absent. Positive results concerning\u0000the effect of PRF on potential post-surgical complication (pain, swelling and trismus) were\u0000reported.\u0000\u0000Conclusion: Few clinical indications could be determined: the literature on the topic was contradictory\u0000and the published data were difficult to interpret. Positive results were generally recorded for\u0000soft tissues and periodontal wound healing. No real benefit of PC application on bone regeneration\u0000was evidenced.\u0000","PeriodicalId":10853,"journal":{"name":"Current opinion in dentistry","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91313495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bond Strength of Ceramic and Metal Orthodontic Brackets to Aged Resinbased Composite Restorations","authors":"A. D. Bona, Ricardo Kochenborger, Luís Antônio Di Guida","doi":"10.2174/2542579X01666180919121640","DOIUrl":"https://doi.org/10.2174/2542579X01666180919121640","url":null,"abstract":"\u0000\u0000Background: Dental resin composites undergo chemical and mechanical degradation.\u0000Thus, the orthodontist should evaluate aged composite restoration surfaces to select the appropriate\u0000protocol to successfully bond orthodontics accessories.\u0000\u0000Objective: This study evaluated the shear bond strength (σ) of metal (M) and ceramic (C) brackets\u0000bonded to aged resin-based composite restorations (ACR) after different surface treatments.\u0000\u0000Methods: ACR specimens (N=160) were fabricated and divided into 8 experimental groups (n=20)\u0000as follows: Mo (control)- M bonded to ACR; MA- M bonded to ACR after acid etching using 38%\u0000phosphoric acid for 20 s (A); MB- M bonded to ACR after surface roughing using a twelve-bladed\u0000bur (B); MBA- M bonded to ACR after B and A; Co (control)- C bonded to ACR; CA- C bonded to\u0000ACR after A; CB- C bonded to ACR after B; CBA- C bonded to ACR after B and A. All specimens\u0000were stored for 24h before σ testing. Data were statistically analyzed using one-way ANOVA and\u0000Tukey post-hoc (α=0.05). Fracture surfaces were examined to determine the failure mode.\u0000\u0000Results: The surface treatments (A, B and BA) produced similar σ values (p>0.05) to ACR when\u0000using the same bracket type. M bracket showed greater σ than C bracket (p<0.05), probably because\u0000of different mechanical retention inherent from bracket type. Inhomogeneous stress distribution\u0000generated complex failures.\u0000\u0000Conclusion: Considering the needs of an orthodontic treatment and the surface treatments evaluated,\u0000sufficient bond strength was produced to ACR, irrespective of bracket type.\u0000","PeriodicalId":10853,"journal":{"name":"Current opinion in dentistry","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90753635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial Profile of Copaifera multijuga Oleoresin and Hydroalcoholic Extract of Leaves Against Oral Pathogens","authors":"Iane Pereira Pimenta, Fariza Abrão, J. J. M. Silva, Larissa Oliveira Costa, H. Rogez, S. Ambrósio, R. Veneziani, J. Bastos, C. Martins","doi":"10.2174/2542579x01666180629100020","DOIUrl":"https://doi.org/10.2174/2542579x01666180629100020","url":null,"abstract":"\u0000\u0000Background: Copaifera multijuga are widely used as medicinal plants in Brazil. Of the\u0000various ethnopharmacological indications of copaiba oleoresins, the antimicrobial activity had been\u0000highlighted.\u0000\u0000Objective: This study aimed to evaluate the oleoresin and the hydroalcoholic extract of leaves from\u0000Copaifera multijuga against oral pathogens in the sessile and in the planktonic modes.\u0000\u0000Methods: Standard strains from the American Type Culture Collection and clinical isolates which\u0000cause both cariogenic and endodontic infections were used. Was evaluated in terms of its Minimum\u0000Inhibitory Concentration (MIC) values by the broth microdilution method in 96-well microplates,\u0000Minimum Bactericidal Concentration (MBC) and biofilm eradication assay.\u0000\u0000Results: The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration\u0000(MBC) assays showed that the oleoresin was effective against some the bacterial strains. Assessment\u0000of the antibiofilm activity of hydroalcoholic extract of leaves from C. multijuga against the evaluated\u0000microaerophilic bacteria in the sessile mode gave IC50 values of 318.0 and 695.6 µg/mL against\u0000S. mitis (ATCC 49456) and A. actinomycetemcomintans (ATCC 43717), respectively. As for the assayed\u0000anaerobic bacteria, the hydroalcoholic extract of leaves gave IC50 of 4554.0, 2218.0, and\u0000600.1 µg/mL against F. nucleatum (Clinical isolate), P. gingivalis (ATCC 33277), and P. micros\u0000(Clinical isolate), respectively, whereas the oleoresin afforded IC50 of 357.1 µg/mL against P.\u0000gingivalis (ATCC 33277).\u0000\u0000Conclusion: The oleoresin and hydroalcoholic extract of leaves displayed satisfactory activity\u0000against the main oral pathogens in both sessile and planktonic modes. The oleoresin and hydroalcoholic\u0000extracts of leaves from C. multijuga are potential candidates for the development of new products\u0000for dental and oral care.\u0000","PeriodicalId":10853,"journal":{"name":"Current opinion in dentistry","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77174735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Dental Management of Patients in The Background of Antithrombotic Use","authors":"G. Sethna, R. Sivasankar, P. Gaitonde, P. Gaitonde","doi":"10.2174/2542579x01666180629094559","DOIUrl":"https://doi.org/10.2174/2542579x01666180629094559","url":null,"abstract":"\u0000\u0000Treatment and perioperative dental management in patients on antithrombotic\u0000medications poses a serious challenge to dental professionals due to perceived risk of\u0000bleeding complications. This article aims to study the anticoagulant / antiplatelet drugs currently\u0000available on the market, review contemporary oral anti-thrombotic treatment and offer management\u0000guidelines in such situations based on the review of pertinent literature.\u0000\u0000\u0000 Science Direct and Ovid databases, PubMed, Scopus and product literature\u0000were accessed to review relevant literature with respect to current anti-thrombotic drugs, indications\u0000for their use in medical conditions, complications related to their use and drug interactions. The\u0000search covered studies published in medical and dental journals in English with a relevant impact\u0000factor over a period of 10 years. Meta analyses, systematic reviews, randomized trials, cohort based\u0000and case-control studies and society-based guidelines were considered. Key words utilized in the\u0000search criteria included Warfarin, Coumarin, Aspirin, P2Y12 inhibitors, Prasugrel, Clopidogrel, Ticagrelor,\u0000Hemorrhage, Anti-thrombin, Platelet aggregation inhibitors and International Normalized\u0000Ratio (INR) and were validated by the MeSH dictionaries.\u0000\u0000\u0000Dental practitioners today, are faced with the challenge of conducting surgical procedures on\u0000patients who are on anti-thrombotic medications for a variety of medical/ surgical co-morbid conditions.\u0000Although there is consensus amongst various studies regarding continuation of warfarin in therapeutic\u0000ranges for dento-alveolar surgery, there is insufficient evidence to reach a consensus in those\u0000groups who are at intermediate or high risk of bleeding. However, most studies and published literature\u0000do agree that there is no real increased risk of bleeding complications during conduct of these procedures\u0000if the patient’s INR is less than 3.5 along with adequate haemostatic measures.\u0000\u0000\u0000Regardless of the procedure to be performed, every case needs to be titrated on its individual\u0000merit based on both patient and surgical factors. Further, it is recommended that INR values\u0000should be established at least 72 hours prior to the surgery, which admits a margin of safety for dose\u0000modification if necessary. A meticulous case history with complementary hemostatic tests and adoption\u0000of adequate local hemostatic measures hold the key to not having the necessity to modify the\u0000antiplatelet or anticoagulation treatment in most cases. Additionally, the advent of newer anticoagulants\u0000and antiplatelets have raised the requirement of dedicated Randomized Clinical Trials to answer\u0000the specific clinical questions of bleeding risk versus thrombo-embolic complications in the perioperative\u0000management of such patients.","PeriodicalId":10853,"journal":{"name":"Current opinion in dentistry","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86040426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Launching of a New Journal and the Challenges of Publishing Scientific Knowledge","authors":"A. D. Bona","doi":"10.2174/2542579X0101190329113306","DOIUrl":"https://doi.org/10.2174/2542579X0101190329113306","url":null,"abstract":"<jats:sec>\u0000<jats:title />\u0000<jats:p />\u0000</jats:sec>","PeriodicalId":10853,"journal":{"name":"Current opinion in dentistry","volume":"223 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72862699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Temporomandibular Joint Disc Displacement without Reduction a Plausible Cause of Condylar Hypoplasia? A Case Report","authors":"Yi-Shu Liu, A. Yap, J. Lei, K. Fu","doi":"10.2174/2542579X01666180919121059","DOIUrl":"https://doi.org/10.2174/2542579X01666180919121059","url":null,"abstract":"\u0000\u0000The causes of mandibular condylar hypoplasia can be congenital or acquired\u0000in nature. Cited local causes of acquired hypoplasia include trauma, infection and irradiation.\u0000We report a case of hypoplastic condyle that was attributed to temporomandibular joint (TMJ) disc\u0000displacement without reduction (DDwoR).\u0000\u0000\u0000 A 16-year-old male presented with restricted mouth opening and right TMJ\u0000pain for 6 months. He was subsequently diagnosed with DDwoR. Conservative treatment comprising\u0000self-care and moist-heat therapy was administered and he was followed for 27 months without\u0000any further interventions. During this period, transitions from “normal” morphology to condylar\u0000flattening / erosion, and eventually a re-modeled smaller “normal” right TMJ were observed.\u0000\u0000\u0000The present case provided initial support that DDwoR could be a plausible cause of\u0000condylar hypoplasia in adolescents / young adults.","PeriodicalId":10853,"journal":{"name":"Current opinion in dentistry","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78020998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meet Our Editor-in-Chief","authors":"A. D. Bona","doi":"10.2174/2542579X0101190329113129","DOIUrl":"https://doi.org/10.2174/2542579X0101190329113129","url":null,"abstract":"<jats:sec>\u0000<jats:title />\u0000<jats:p />\u0000</jats:sec>","PeriodicalId":10853,"journal":{"name":"Current opinion in dentistry","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89375037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Among Methods to Measure Tooth Color in Clinical Trials Evaluating Tooth Bleaching","authors":"A. Faria-E-Silva","doi":"10.2174/2542579x01666180416112018","DOIUrl":"https://doi.org/10.2174/2542579x01666180416112018","url":null,"abstract":"\u0000\u0000Objective: This study aimed to assess possible differences in results provided by two\u0000shade guides and a spectrophotometer used to measure the color changes during tooth bleaching.\u0000\u0000Methods: Fifty-six patients underwent two sessions of in-office tooth bleaching with a 35% hydrogen\u0000peroxide with a week of an interval between them. The color evaluation was performed using\u0000shade match with two guide scales (Vita Classical, and Vita Bleach Guide) and a spectrophotometer\u0000providing CieLab data. The color was assessed at baseline and 7 days after each session, and 30\u0000days after the last session. Data from scales were arranged in scores according to lightness (lowest to\u0000highest) and the color changes were calculated based on baseline data. For CieLab data, ΔL, Δa, Δb,\u0000and ΔE were calculated for each assessment time. Differences between the color changes observed\u0000in each session were assessed by Wilcoxon test (α = 0.05). Friedman`s test and One-way repeated\u0000measures ANOVA were used to analyze color changes among the assessment times. Spearman`s test\u0000was used to evaluate the correlation between the shade guide scores and data from Cielab.\u0000\u0000Results: All methods of color measurement demonstrated any additional effect of second bleaching\u0000session on color change, and stable color after 30 days (p < 0.001 for all methods). Both shade guide\u0000scales presented low correlation coefficients with ΔL, and moderate coefficients with Δb, Δa, and\u0000ΔE.\u0000\u0000Conclusion: Despite the weak/ moderate correlation among the methods used to measure tooth\u0000color, all methods showed similar results of tooth bleaching effectiveness.\u0000","PeriodicalId":10853,"journal":{"name":"Current opinion in dentistry","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82096785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in Color and Whiteness Evaluations in Dentistry","authors":"M. M. Pérez, O. Pecho, R. Ghinea, R. Pulgar, A. D. Bona","doi":"10.2174/2542579x01666180719125137","DOIUrl":"https://doi.org/10.2174/2542579x01666180719125137","url":null,"abstract":"\u0000\u0000 The final goal of color measurement or shade specification in dentistry is\u0000the reproduction by prosthetic materials of all important appearance characteristics of natural oral\u0000structures. The application of color science in dentistry is an objective way to measure and evaluate\u0000such structures and dental materials in clinical practice and dental research.\u0000\u0000\u0000 Literature on color science was reviewed to present new metrics to evaluate color differences\u0000of dental materials and dental structures. Visual acceptability and perceptibility values of color\u0000differences are reviewed and new whiteness indexes to describe whiteness in dentistry are presented.\u0000\u0000\u0000In the last decade, the CIELAB 50:50% perceptibility and acceptability thresholds were set\u0000to 1.2 and 2.7, respectively, and the CIEDE2000 50:50% perceptibility and acceptability thresholds\u0000were set to 0.8 and 1.8. The CIEDE2000 color-difference formula became increasingly popular in\u0000dentistry. Developments in color science have led to the description of tooth whiteness and changes\u0000in tooth whiteness based on whiteness indexes, with the most relevant being the WID whiteness index,\u0000which is a customized index based in CIELAB color space.\u0000\u0000\u0000\u0000 The application of color science in dentistry has allowed the precise description of\u0000tooth color and whiteness. The revised and new CIEDE2000 color-difference formula is expected to\u0000fully replace the outdated CIELAB formula in almost all dental applications. Recent psychophysical\u0000studies have reported values of visual thresholds and new whiteness indexes, which can serve as\u0000quality control tools to guide the selection of esthetic dental materials, evaluate clinical performance,\u0000and interpret visual and instrumental findings in clinical dentistry, dental research, and subsequent\u0000standardization.","PeriodicalId":10853,"journal":{"name":"Current opinion in dentistry","volume":"6 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85585902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}