Copeia最新文献

{"title":"Summary of the Meetings","authors":"","doi":"10.1643/ot-16-519","DOIUrl":"https://doi.org/10.1643/ot-16-519","url":null,"abstract":"THE 96 annual meeting (and 100 anniversary) of the American Society of Ichthyologists and Herpetologists (ASIH) was held at the New Orleans Marriot from 6–10 July 2016 in conjunction with the 32 annual meeting of the American Elasmobranch Society (AES), the 74 annual meeting of the Herpetologists’ League (HL), and the annual meeting of the Neotropical Ichthyological Association. A total of 1308 attendees were in New Orleans: 633 professionals, 629 graduate students (seven of whom were volunteers and one high school student), 25 accompanying persons, and 21 exhibitors. These attendees represented 29 nations (Argentina, Australia, Bahamas, Belize, Brazil, Canada, Chile, Colombia, Costa Rica, Dutch Caribbean, France, Germany, Ireland, Italy, Japan, Mexico, Netherlands, New Zealand, Pakistan, Panama, Portugal, South Africa, Spain, Sudan, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States). The attendance to this 100 anniversary meeting was nearly double the previous meeting, a great success we should strive to continue.","PeriodicalId":10701,"journal":{"name":"Copeia","volume":"104 1","pages":"981 - 988"},"PeriodicalIF":2.6,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46816087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food allergy: History, definitions and treatment approaches.","authors":"Pooja Purswani, Edwin H Kim","doi":"10.2500/jfa.2022.4.220007","DOIUrl":"10.2500/jfa.2022.4.220007","url":null,"abstract":"<p><p>Allergen-specific immunotherapy for the treatment of immunoglobulin E mediated food allergies, specifically oral, epicutaneous, and sublingual immunotherapies, are promising options that may provide an alternative to strict avoidance of the dietary allergen. Of these potential therapies, oral immunotherapy is the furthest along in development, with strong evidence of efficacy in clinical trials, and has achieved regulatory approval. Nevertheless, oral immunotherapy may not be a suitable therapy for some patients due to the risk of adverse effects. In contrast to oral immunotherapy, epicutaneous and sublingual immunotherapies have demonstrated modest efficacy in clinical trials, with a favorable adverse effect profile, which suggests that these therapies may be possible contenders to oral immunotherapy in certain clinical situations. Familiarity with the various treatment approaches is vital for guiding patients and families as more therapeutic modalities become available for use outside of the research setting.</p>","PeriodicalId":10701,"journal":{"name":"Copeia","volume":"1935 1","pages":"22-27"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11250212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91147990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of the First COVID-19 Lockdown Period on the Inpatient and Outpatient Volume of a University Based Tertiary Referral Center with Corneal Subspecialization in Germany.","authors":"Nadir Maiassi, Kassandra Xanthopoulou, Ursula Löw, Berthold Seitz","doi":"10.2147/OPTH.S335551","DOIUrl":"10.2147/OPTH.S335551","url":null,"abstract":"<p><strong>Background/aims: </strong>To determine the impact of COVID-19 on the number of in- and outpatients surgical and diagnostic procedures performed at a southwestern German university hospital with corneal subspecialization.</p><p><strong>Methods: </strong>A retrospective examination of the number of inpatients, several outpatients subunits, in- and outpatient surgeries as well as diagnostic procedures at the Department of Ophthalmology, Saarland University Medical Centre during the COVID-19 pandemic \"lockdown period\" from 18 March until 8 May 2020 in comparison with the corresponding period in 2019 (source: SAP database and electronic patient record FIDUS).</p><p><strong>Results: </strong>The year 2020 showed a significant decrease in the number of inpatient surgeries with a total number of 285 vs 412 in 2019. However, the number of corneal transplantations increased significantly (60 in 2020 vs 54 in 2019, p=0.0089). In the various outpatient units of our department, we observed a significant decrease in the number of consultations (1.711 in 2020 vs 3.194 in 2019), especially for cataract surgery consultations (34 vs 137, p<0.0001). The number of outpatient surgeries was significantly reduced in 2020, especially for cataract surgery (64 vs 216, p=0.007) and intravitreal injections (577 vs 768, p<0.0001).</p><p><strong>Conclusion: </strong>Despite taking all the necessary precautions to ensure that our medical care can continue to be available reliably and completely safe during the \"Corona lockdown period\", the number of in- and outpatient surgeries and the number of outpatient consultations decreased significantly. However, the number of corneal transplantations still increased.</p>","PeriodicalId":10701,"journal":{"name":"Copeia","volume":"1986 1","pages":"1795-1805"},"PeriodicalIF":0.0,"publicationDate":"2022-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90334746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASD/OCD-Linked Protocadherin-10 Regulates Synapse, But Not Axon, Development in the Amygdala and Contributes to Fear- and Anxiety-Related Behaviors.","authors":"Naosuke Hoshina, Erin M Johnson-Venkatesh, Veronica R Rally, Jaanvi Sant, Miyuki Hoshina, Mariel P Seiglie, Hisashi Umemori","doi":"10.1523/JNEUROSCI.1843-21.2022","DOIUrl":"10.1523/JNEUROSCI.1843-21.2022","url":null,"abstract":"<p><p>The <i>Protocadherin-10</i> (<i>PCDH10</i>) gene is associated with autism spectrum disorder (ASD), obsessive-compulsive disorder (OCD), and major depression (MD). The PCDH10 protein is a homophilic cell adhesion molecule that belongs to the δ2-protocadherin family. PCDH10 is highly expressed in the developing brain, especially in the basolateral nucleus of the amygdala (BLA). However, the role of PCDH10 <i>in vivo</i> has been debatable: one paper reported that a <i>Pcdh10</i> mutant mouse line showed changes in axonal projections; however, another <i>Pcdh10</i> mutant mouse line was reported to have failed to detect axonal phenotypes. Therefore, the actual roles of PCDH10 in the brain remain to be elucidated. We established a new <i>Pcdh10</i> KO mouse line using the CRISPR/Cas9 system, without inserting gene cassettes to avoid nonspecific effects, examined the roles of PCDH10 in the brain, and studied the behavioral consequences of <i>Pcdh10</i> inactivation. Here, we show that <i>Pcdh10</i> KO mice do not show defects in axonal development. Instead, we find that <i>Pcdh10</i> KO mice exhibit impaired development of excitatory synapses in the dorsal BLA. We further demonstrate that male <i>Pcdh10</i> KO mice exhibit reduced anxiety-related behaviors, impaired fear conditioning, decreased stress-coping responses, and mildly impaired social recognition and communication. These results indicate that PCDH10 plays a critical role in excitatory synapse development, but not axon development, in the dorsal BLA and that PCDH10 regulates anxiety-related, fear-related, and stress-related behaviors. Our results reveal the roles of PCDH10 in the brain and its relationship to relevant psychiatric disorders such as ASD, OCD, and MD.<b>SIGNIFICANCE STATEMENT</b><i>Protocadherin-10</i> (<i>PCDH10</i>) encodes a cell adhesion molecule and is implicated in autism spectrum disorder (ASD), obsessive-compulsive disorder (OCD), and major depression (MD). PCDH10 is highly expressed in the basolateral nucleus of the amygdala (BLA). However, the phenotypes of previously published <i>Pcdh10</i> mutant mice are debatable, and some are possibly because of the nonspecific effects of the <i>LacZ/Neo</i> cassette inserted in the mice. We have generated a new <i>Pcdh10</i> mutant mouse line without the <i>LacZ/Neo</i> cassette. Using our new mouse line, we reveal the roles of PCDH10 for excitatory synapse development in the BLA. The mutant mice exhibit anxiety-related, fear-related, and stress-related behaviors, which are relevant to ASD, OCD, and MD, suggesting a possible treatment strategy for such psychiatric disorders.</p>","PeriodicalId":10701,"journal":{"name":"Copeia","volume":"1998 1","pages":"4250-4266"},"PeriodicalIF":0.0,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90440493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to correspondence of Martin et al.","authors":"Michael R Perkin, Rosie Vincent, Matthew J Ridd","doi":"10.1111/cea.14126","DOIUrl":"10.1111/cea.14126","url":null,"abstract":"","PeriodicalId":10701,"journal":{"name":"Copeia","volume":"1965 1","pages":"583-584"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91318791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Summary Of The Meetings","authors":"J. Mceachran, Charles R. Peterson, Mark Peterson, Paulo Petry, Harvey Pough, J. Pramuk, R. Reis","doi":"10.1643/ot-08-170","DOIUrl":"https://doi.org/10.1643/ot-08-170","url":null,"abstract":"The 88 annual meeting of the American Society of Ichthyologists and Herpetologists (ASIH) was held at the Le Centre Sheraton Montréal Hotel, Montréal, Quebec, Canada from 23–28 July 2008, in conjunction with the 24 annual meeting of the American Elasmobranch Society (AES), the 66 annual meeting of the Herpetologists’ League (HL), the 51 annual meeting of the Society for the Study of Amphibians and Reptiles (SSAR), and the annual meeting of the Canadian Association of Herpetologists.","PeriodicalId":10701,"journal":{"name":"Copeia","volume":"2008 1","pages":"955 - 964"},"PeriodicalIF":2.6,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1643/ot-08-170","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49555208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Taxonomic Index","authors":"","doi":"10.1643/OT-12-145","DOIUrl":"https://doi.org/10.1643/OT-12-145","url":null,"abstract":"Adenocalymma 56, 438 Adenopus 54 Adesmia 54 Adlumia 22 Aegiphila 398 Afromendoncia 54, 56, 57, 58 Aganosma 108, 431 Agatea 36 Agelaea obliqua 441 Agelaea trinervis 441 i4foWa 66, 247 Allamanda 108,431 Alyxia 431 Ambelania 431 Ampelocissus 465 Ampelocissus asarifolia 465 Ampelocissus ochracea 465 Ampelopsis 247, 465 Anamirta 455 Ancistrophyllum secundiflorum 434 Anechites 432 Anemopaegma 56, 438 Anisosperma 444 Anodendron 432 Anomospermum 57, 128 Anredera 328 Anredera cordifolia 437 Anredera diffusa 437 Anthurium 433 Antigonum 22 Antizoma capensis 340 Apodanthera 444 Apodanthera undulata 343 Archontophoenix cunninghamiana 369 y4reca catechu 459 Argyreia 54, 442 Aristolochia 20, 55, 56, 64, 109, 193, 194, 247, 297-8, 405, 435 Aristolochia elegans 298 Aristolochia maxima 110 Aristolochia taliscana 174 Arrabidaea 56, 319, 437-8 Arrabidaea chica 437-8 Arrabidaea pubescens 438 Artabotrys 20, 22, 102, 430 Artemisia herba-alba 350 Asparagus 104, 340 Asparagus acutifolius 348 Atraphaxis 55","PeriodicalId":10701,"journal":{"name":"Copeia","volume":"2012 1","pages":"791 - 808"},"PeriodicalIF":2.6,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1643/OT-12-145","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48662591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MomL inhibits bacterial antibiotic resistance through the starvation stringent response pathway.","authors":"Qin Dou, Jin Yuan, Rilei Yu, Jiahui Yang, Jiayi Wang, Yuxiang Zhu, Jing Zhong, Hongan Long, Zhiqing Liu, Xianghong Wang, Yuying Li, Yichen Xiao, Jiazhen Liang, Xiao-Hua Zhang, Yan Wang","doi":"10.1002/mlf2.12016","DOIUrl":"10.1002/mlf2.12016","url":null,"abstract":"<p><p>Antibiotic resistance in gram-negative pathogens has become one of the most serious global public health threats. The role of the <i>N</i>-acyl homoserine lactone (AHL)-mediated signaling pathway, which is widespread in gram-negative bacteria, in the bacterial resistance process should be studied in depth. Here, we report a degrading enzyme of AHLs, MomL, that inhibits the antibiotic resistance of <i>Pseudomonas aeruginosa</i> through a novel mechanism. The MomL-mediated reactivation of kanamycin is highly associated with the <i>relA</i>-mediated starvation stringent response. The degradation of AHLs by MomL results in the inability of LasR to activate <i>relA</i>, which, in turn, stops the activation of downstream <i>rpoS</i>. Further results show that <i>rpoS</i> directly regulates the type VI secretion system H2-T6SS. Under MomL treatment, inactivated RpoS fails to regulate H2-T6SS; therefore, the expression of effector phospholipase A is reduced, and the adaptability of bacteria to antibiotics is weakened. MomL in combination with kanamycin is effective against a wide range of gram-negative pathogenic bacteria. Therefore, this study reports a MomL-antibiotic treatment strategy on antibiotic-resistant bacteria and reveals its mechanism of action.</p>","PeriodicalId":10701,"journal":{"name":"Copeia","volume":"1959 1","pages":"428-442"},"PeriodicalIF":5.4,"publicationDate":"2022-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10989899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91238915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Taxonomic Index","authors":"","doi":"10.1643/OT-17-585","DOIUrl":"https://doi.org/10.1643/OT-17-585","url":null,"abstract":"","PeriodicalId":10701,"journal":{"name":"Copeia","volume":"105 1","pages":"191 - 205"},"PeriodicalIF":2.6,"publicationDate":"2022-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1643/OT-17-585","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44031923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using a Non-Wearable Actigraphy in Nursing Care for Dementia With Lewy Bodies.","authors":"Chiaki Fukuda, Yoko Higami, Kazue Shigenobu, Hideki Kanemoto, Miyae Yamakawa","doi":"10.1177/15333175221082747","DOIUrl":"10.1177/15333175221082747","url":null,"abstract":"<p><p>People who have dementia with Lewy bodies often have sleep disorders. We used non-wearable devices to record and categorize the sleep patterns of patients with Lewy body dementia. Individual sleep data at a dementia-care unit in Japan were recorded using non-wearables. One week's worth of data from 18 patients was analyzed. Median metrics for all participants were the following: sleep efficiency, 68% (23-89); sleep duration at night, 6.8 hours (1.6-11.1); times getting out of bed at night, 3.5 (0-13). We identified three types of abnormal sleep: extremely short sleep duration, excessive sleep duration at night, and excessive number of times getting out of bed at night. Sleep disturbances in Lewy body dementia patients are treated using various practices; staff must choose the most effective plan for each patient's situation. Monitoring patient sleep using non-wearable provides more objective data that can help staff better personalize nursing care.</p>","PeriodicalId":10701,"journal":{"name":"Copeia","volume":"2005 1","pages":"15333175221082747"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89525349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}