Congenital Heart Disease最新文献

{"title":"Intraoperative Blood Glucose Levels and Postoperative Acute Kidney Injury in Pediatric Patients Having Congenital Heart Surgery under Cardiopulmonary Bypass","authors":"Dongyun Bie, Hongbai Wang, Chaobin Zhang, Chunrong Wang, Yuan Jia, Su Yuan, Sheng Shi, Jiangshan Huang, Jianhui Wang, Fuxia Yan","doi":"10.32604/chd.2023.028017","DOIUrl":"https://doi.org/10.32604/chd.2023.028017","url":null,"abstract":"<b>Purpose:</b> This study sought to explore the effect of intraoperative mean blood glucose levels and variability on postoperative acute kidney injury (AKI) in children undergoing congenital cardiac surgery. <b>Methods:</b> We conducted a prospective nested case-control study in children (age < 18 years) undergoing congenital heart surgery with cardiopulmonary bypass (CPB) at the Fuwai Hospital between April 01, 2022 and July 30, 2022. Cases were individuals who developed AKI within the first postoperative 7 days (AKI group) and controls were those without AKI (Non-AKI group) according to KDIGO criteria. AKI and Non-AKI groups unmatched and 1:1 matched by age, sex, and baseline serum creatinine were separately analyzed. Multivariate logistic and conditional logistic regressions were used to assess the associations between blood glucose variables and AKI. <b>Results:</b> 688 consecutively approached patients were included in the final analysis. On multivariate analysis, intra-CPB (adjusted odds ratio [OR] 0.802; 95% confidence interval [CI], 0.706 to 0.912; <i>p </i>= 0.001) and post-CPB (adjusted OR 0.830; 95% CI, 0.744 to 0.925; <i>p </i>= 0.001) blood glucose levels were associated with postoperative AKI. There were no significant differences in pre-CPB blood glucose (adjusted OR 0.926; 95% CI, 0.759 to 1.129; <i>p </i>= 0.446) or intraoperative glycemic fluctuations (adjusted OR 0.905; 95% CI, 0.723 to 1.132; <i>p </i>= 0.382) between AKI and Non-AKI groups. Results based on matched cases and controls were consistent with those from the unmatched analyses. <b>Conclusion:</b> Higher intraoperative blood glucose levels during and after CPB were protective factors against postoperative AKI in pediatric patients after congenital heart surgery.","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135400902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Outcomes of Systemic-to-Pulmonary Artery Shunt in Patients with Functional Single Ventricle and Heterotaxy Syndrome","authors":"Shota Kawai, Takashi Kido, Yuta Teguri, Koji Miwa, Tomomitsu Kanaya, Yoichiro Ishii, Hisaaki Aoki, Futoshi Kayatani, Sanae Tsumura","doi":"10.32604/chd.2023.042243","DOIUrl":"https://doi.org/10.32604/chd.2023.042243","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135401324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Risk Factors for Early Mortality in Surgical Shunt Palliation: Time for a Change?","authors":"François-Xavier Van Vyve, Karlien Carbonez, Jelena Hubrechts, Geoffroy de Beco, Jean E. Rubay, Mona Momeni, Thierry Detaille, Alain J. Poncelet","doi":"10.32604/chd.2023.042344","DOIUrl":"https://doi.org/10.32604/chd.2023.042344","url":null,"abstract":"<b>Objectives:</b> Over the last decade, neonatal repair has been advocated for many congenital heart diseases. However, specific subgroups of complex congenital heart disease still require temporary palliation for which both surgical and endovascular techniques are currently available. We reviewed our institutional experience with shunt palliation with an emphasis on risk factors for early mortality. <b>Methods:</b> This is a single-center retrospective study on 175 patients undergoing surgery for central shunt or modified Blalock-Taussig shunt. All data were extracted from a prospectively collected computerized database. We identified risk factors for early mortality by uni- and multi-variable analysis. All data were censored at the time of death or shunt take-down operation. <b>Results:</b> Mean age and weight at surgery were 24 days (IQR [7–95]) and 3.4 kg (IQR [2.9–4.8]), respectively, with 96 neonates (55%). Most patients had a biventricular heart disease (115 patients, 66%), and 51 patients (29.1%) had univentricular heart disease. Thoracotomy was performed in 129 patients (74%). Cardiopulmonary bypass was used in 23 patients (13%). The median intensive care and overall length of stay were 4 days (IQR [2–9]) and 18 days (IQR [13–29]), respectively. In-hospital mortality was 8.6% (15/175). By multivariable regression analysis, prematurity (HR 5.6 [2.1–14.7]), CPB use (HR 6.7 [2.2–18.6]), unplanned <30-day reoperation (HR 3.5 [1.2–10]) or catheterization (HR 4.5 [1.2–16.9]) were all significant predictors of early mortality. <b>Conclusions:</b> Procedural-related mortality remains high (8.6%) in surgical shunt palliation. For patients with prematurity, low weight at birth, or if the use of cardiopulmonary bypass is contemplated, alternative endovascular techniques of palliation should be considered together with longitudinal follow-up studies.","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135559344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of Transcatheter Closure in Outlet-Type Ventricular Septal Defect after 1 Year","authors":"S. Roymanee, N. Su-angka, Worakan Promphan, Kanjarut Wongwaitaweewong, Jirayut Jarutach, Rujira Buntharikpornpun, Pimpak Prachasilchai","doi":"10.32604/chd.2023.021238","DOIUrl":"https://doi.org/10.32604/chd.2023.021238","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"39 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69719882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Intracardiac and Extracardiac Deformities in Patients with Various Types of Pulmonary Atresia by Dual-Source Computed Tomography","authors":"Wen Qian, Xinzhu Zhou, K. Shi, Li Jiang, Xi Liu, Liting Shen, Zhi Yang","doi":"10.32604/chd.2023.023542","DOIUrl":"https://doi.org/10.32604/chd.2023.023542","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69720051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary Evaluation of Hemodynamic Effects of Fontan Palliation on Renal Artery Using Computational Fluid Dynamics","authors":"Jinlong Liu, Jing Shi, Weiru Luo, Zhirong Tong, Lefei Yang, Peixuan Sun, Tianyi Li, Jun Du, Qian Wang","doi":"10.32604/chd.2023.025005","DOIUrl":"https://doi.org/10.32604/chd.2023.025005","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69720155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minor Pressure Differences within the Fontan-Anastomosis in Patients with Total Cavopulmonary Connection by 4D-Flow Magnetic Resonance Imaging","authors":"Nerejda Shehu, Christian Meierhofer, Anja Hennemuth, Markus H黮lebrand, Pavlo Yevtushenko, Peter Ewert, Stefan Martinoff, Heiko Stern","doi":"10.32604/chd.2023.031075","DOIUrl":"https://doi.org/10.32604/chd.2023.031075","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135401627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Pulmonary Arteries Growth after Initial Shunt Palliation in Neonates and Infants","authors":"François-Xavier Van Vyve, Karlien Carbonez, Geoffroy de Beco, Stéphane Moniotte, Jean E. Rubay, Mona Momeni, Laurent Houtekie, Alain J. Poncelet","doi":"10.32604/chd.2023.042341","DOIUrl":"https://doi.org/10.32604/chd.2023.042341","url":null,"abstract":"<b>Objective:</b> Despite increasing enthusiasm for neonatal repair, patients with ductal-dependent circulation (pulmonary/systemic) or restrictive pulmonary blood flow still require initial palliation. Ductal stenting has emerged as an endovascular approach whereas modified-Blalock-Taussig and central shunt remain surgical references. In this study, we analyzed the relationship between pulmonary artery growth, sites of shunt connection, or antegrade pulmonary blood flow in surgically placed shunts. The need for secondary catheter-based interventions or pulmonary arterioplasty was also investigated. <b>Methods:</b> A retrospective single-center study analyzing 175 patients undergoing surgery for a central or modified-Blalock-Taussig shunt. Outcome growth variables were right pulmonary artery/left pulmonary artery diameters/Z scores, the indexed sum area (right pulmonary artery + left pulmonary artery), and the pulmonary symmetry index. Three imaging modalities were used: angiography, computed tomography, and echocardiography. <b>Results:</b> At baseline, pulmonary arteries were larger in patients with antegrade pulmonary blood flow (Nakata index 137 <i>vs</i>. 114, <i>p</i> = 0.047) as well as in patients receiving a modified-Blalock-Taussig shunt (Nakata index 138 <i>vs</i>. 84, <i>p</i> < 0.001). At the time of shunt takedown, both the right pulmonary artery and left pulmonary artery had normalized their diameter. The Nakata index increased from 134 to 233 mm2/m2 (<i>p</i> < 0.001). The pulmonary artery index remained stable (0.86) over time. During the inter-stage period, shunt-related pulmonary artery stenosis and juxta-ductal stenosis were diagnosed in 16 (10%) and 17 patients (11%), respectively. <b>Conclusions:</b> Surgical shunt palliation allows normal pulmonary artery growth. Pulmonary artery stenosis was either shunt-related (10%) or secondary to juxta-ductal stenosis (11%). Close echographic follow-up allows early diagnosis and treatment of juxta-ductal stenosis.","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"274 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135560790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomic Correlates of Mitral Systolic Anterior Motion in Transposition of the Great Arteries Following Atrial Switch Operation","authors":"Norman Aiad, Mark V. Sherrid, Adam J. Small, Youssef Elnabawi, Jodi L. Feinberg, L. Axel, R. Mosca, T. K. Susheel Kumar, M. Argilla, Dan G. Halpern","doi":"10.32604/chd.2023.025853","DOIUrl":"https://doi.org/10.32604/chd.2023.025853","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69719861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Treat-Repair-Treat”: Management of Left Main Coronary Compression by a Pulmonary Artery Aneurysm in a Patient with Atrial Septal Defect and Significant Pulmonary Hypertension","authors":"Andrei George Iosifescu, R. Enache, I. Marinică, C. Radu, Vlad Anton Iliescu","doi":"10.32604/chd.2023.026598","DOIUrl":"https://doi.org/10.32604/chd.2023.026598","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69720127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}