{"title":"Association of congenital heart defects (CHD) with factors related to maternal health and pregnancy in newborns in Puerto Rico.","authors":"Yamixa Delgado, Caliani Gaytan, Naydi Perez, Eric Miranda, Bryan Colón Morales, Mónica Santos","doi":"10.32604/chd.2024.046339","DOIUrl":"10.32604/chd.2024.046339","url":null,"abstract":"<p><strong>Background: </strong>Given the pervasive issues of obesity and diabetes both in Puerto Rico and the broader United States, there is a compelling need to investigate the intricate interplay among BMI, pregestational, and gestational maternal diabetes, and their potential impact on the occurrence of congenital heart defects (CHD) during neonatal development.</p><p><strong>Methods: </strong>Using the comprehensive System of Vigilance and Surveillance of Congenital Defects in Puerto Rico, we conducted a focused analysis on neonates diagnosed with CHD between 2016 and 2020. Our assessment encompassed a range of variables, including maternal age, gestational age, BMI, pregestational diabetes, gestational diabetes, hypertension, history of abortion, and presence of preeclampsia.</p><p><strong>Results: </strong>A cohort of 673 patients was included in our study. The average maternal age was 26 years, within a range of 22 to 32 years. The mean gestational age measured 39 weeks, with a median span of 38 to 39 weeks. Of the 673 patients, 274 (41%) mothers gave birth to neonates diagnosed with CHD. Within this group, 22 cases were linked to pre-gestational diabetes, while 202 were not; 20 instances were associated with gestational diabetes, compared to 200 without; and 148 cases exhibited an overweight or obese BMI, whereas 126 displayed a normal BMI.</p><p><strong>Conclusion: </strong>We identified a statistically significant correlation between pre-gestational diabetes mellitus and the occurrence of CHD. However, our analysis did not show a statistically significant association between maternal BMI and the likelihood of CHD. These results may aid in developing effective strategies to prevent and manage CHD in neonates.</p>","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"19 1","pages":"19-31"},"PeriodicalIF":0.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11192526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141442261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Oreto, G. Mandraffino, P. Ciliberti, Teresa P. Santangelo, P. Romeo, A. Celona, P. Gitto, L. Galletti, Fiore S. Iorio, Alfredo di Pino, A. Secinaro, P. Guccione, Robert H. Anderson, S. Agati
{"title":"Classifying Cardiac Anomalies in Right and Left Isomerism: Concordant and Discordant Patterns","authors":"L. Oreto, G. Mandraffino, P. Ciliberti, Teresa P. Santangelo, P. Romeo, A. Celona, P. Gitto, L. Galletti, Fiore S. Iorio, Alfredo di Pino, A. Secinaro, P. Guccione, Robert H. Anderson, S. Agati","doi":"10.32604/chd.2022.023619","DOIUrl":"https://doi.org/10.32604/chd.2022.023619","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69719629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pentalogy of Cantrell with Pentalogy of Fallot and Left Ventricular Diverticulum","authors":"Weimin Zhang, Zheng Liu, Tao Zhu, Q. Huo","doi":"10.32604/chd.2023.026404","DOIUrl":"https://doi.org/10.32604/chd.2023.026404","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69719992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Cresti, S. Sparla, S. Stefanelli, A. Picchi, U. Limbruno
{"title":"Ventricular Septal Crypts: Remnants of Spontaneous Interventricular Defect Closure?","authors":"A. Cresti, S. Sparla, S. Stefanelli, A. Picchi, U. Limbruno","doi":"10.32604/chd.2023.025639","DOIUrl":"https://doi.org/10.32604/chd.2023.025639","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69720271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quality of Life in Congenital Heart Disease Patients According to Their Anatomical and Physiological Classification","authors":"Efr閚 Mart韓ez-Quintana, Hiurma Estupi襻n-Le髇, Ana Beatriz Rojas-Brito, Liuva D閚iz-D閚iz, Alejandro Barreto-Mart韓, Fayna Rodr韌uez-Gonz醠ez","doi":"10.32604/chd.2021.013308","DOIUrl":"https://doi.org/10.32604/chd.2021.013308","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69713592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alain J. Poncelet, Maureen Peers de Nieuwburgh, St閜hane Moniotte, G. de Beco, K. Carbonez, Jean E. Rubay, T. Detaille, L. Houtekie, M. Momeni
{"title":"Cardiac Surgery with Cardiopulmonary Bypass in Low-Weight or Preterm Neonates: A Retrospective Study Analyzing Early Outcome","authors":"Alain J. Poncelet, Maureen Peers de Nieuwburgh, St閜hane Moniotte, G. de Beco, K. Carbonez, Jean E. Rubay, T. Detaille, L. Houtekie, M. Momeni","doi":"10.32604/chd.2023.022636","DOIUrl":"https://doi.org/10.32604/chd.2023.022636","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69719903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Suvorov, V. Zaitsev, N. Pilyugov, O. Tereshenko, M. Komissarov
{"title":"Emergency Hybrid Correction in a Newborn with Critical Aortic Valve Stenosis with Acute Pulmonary Edema in the First Hour after Birth","authors":"V. Suvorov, V. Zaitsev, N. Pilyugov, O. Tereshenko, M. Komissarov","doi":"10.32604/chd.2023.025522","DOIUrl":"https://doi.org/10.32604/chd.2023.025522","url":null,"abstract":"","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69720173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dongyun Bie, Hongbai Wang, Chaobin Zhang, Chunrong Wang, Yuan Jia, Su Yuan, Sheng Shi, Jiangshan Huang, Jianhui Wang, Fuxia Yan
{"title":"Intraoperative Blood Glucose Levels and Postoperative Acute Kidney Injury in Pediatric Patients Having Congenital Heart Surgery under Cardiopulmonary Bypass","authors":"Dongyun Bie, Hongbai Wang, Chaobin Zhang, Chunrong Wang, Yuan Jia, Su Yuan, Sheng Shi, Jiangshan Huang, Jianhui Wang, Fuxia Yan","doi":"10.32604/chd.2023.028017","DOIUrl":"https://doi.org/10.32604/chd.2023.028017","url":null,"abstract":"<b>Purpose:</b> This study sought to explore the effect of intraoperative mean blood glucose levels and variability on postoperative acute kidney injury (AKI) in children undergoing congenital cardiac surgery. <b>Methods:</b> We conducted a prospective nested case-control study in children (age < 18 years) undergoing congenital heart surgery with cardiopulmonary bypass (CPB) at the Fuwai Hospital between April 01, 2022 and July 30, 2022. Cases were individuals who developed AKI within the first postoperative 7 days (AKI group) and controls were those without AKI (Non-AKI group) according to KDIGO criteria. AKI and Non-AKI groups unmatched and 1:1 matched by age, sex, and baseline serum creatinine were separately analyzed. Multivariate logistic and conditional logistic regressions were used to assess the associations between blood glucose variables and AKI. <b>Results:</b> 688 consecutively approached patients were included in the final analysis. On multivariate analysis, intra-CPB (adjusted odds ratio [OR] 0.802; 95% confidence interval [CI], 0.706 to 0.912; <i>p </i>= 0.001) and post-CPB (adjusted OR 0.830; 95% CI, 0.744 to 0.925; <i>p </i>= 0.001) blood glucose levels were associated with postoperative AKI. There were no significant differences in pre-CPB blood glucose (adjusted OR 0.926; 95% CI, 0.759 to 1.129; <i>p </i>= 0.446) or intraoperative glycemic fluctuations (adjusted OR 0.905; 95% CI, 0.723 to 1.132; <i>p </i>= 0.382) between AKI and Non-AKI groups. Results based on matched cases and controls were consistent with those from the unmatched analyses. <b>Conclusion:</b> Higher intraoperative blood glucose levels during and after CPB were protective factors against postoperative AKI in pediatric patients after congenital heart surgery.","PeriodicalId":10666,"journal":{"name":"Congenital Heart Disease","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135400902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}