Congenital Anomalies最新文献_第3页

Pregnancy outcomes after first-trimester exposure to fluoroquinolones: Findings based on an integrated database from two Japanese institutions 第一孕期接触氟喹诺酮类药物后的妊娠结局：根据日本两家医疗机构的综合数据库得出的结论。

IF 1.3 4区医学

Congenital Anomalies Pub Date : 2024-06-27 DOI: 10.1111/cga.12577

Mikako Goto, Tatsuhiko Anzai, Ritsuko Yamane, Naho Yakuwa, Kunihiko Takahashi, Atsuko Murashima

{"title":"Pregnancy outcomes after first-trimester exposure to fluoroquinolones: Findings based on an integrated database from two Japanese institutions","authors":"Mikako Goto, Tatsuhiko Anzai, Ritsuko Yamane, Naho Yakuwa, Kunihiko Takahashi, Atsuko Murashima","doi":"10.1111/cga.12577","DOIUrl":"10.1111/cga.12577","url":null,"abstract":"Given the paucity of safety data on fluoroquinolone antibiotics in pregnancy, a prospective observational cohort study was conducted in pregnant women who sought help and advice on drug use at two teratology information institutes in Japan. The primary endpoint of the study was the incidence of major congenital anomalies. The study population included pregnant women exposed to (i) fluoroquinolones (fluoroquinolone group), (ii) β-lactams (infectious control group), or (iii) other agents considered to be nonteratogenic in humans (nonteratogenic control group) during the first trimester. The frequency of major congenital anomalies was compared across groups using a logistic regression model that adjusted for maternal age, smoking status, drinking status, facility consulted, and time of consultation. The fluoroquinolone group consisted of 411 women who had 383 children born alive. The infectious control and nonteratogenic control groups consisted of 1416 and 1482 women who had 1322 and 1401 children born alive, respectively. The incidence of major congenital anomalies was 1.5%, 2.0%, and 1.6% in the fluoroquinolone group, infectious control, and nonteratogenic control groups, respectively. Logistic regression showed that fluoroquinolone exposure is not a significant risk factor for major congenital anomalies. In conclusion, first-trimester exposure to fluoroquinolone antibiotics was not associated with increased maternal or fetal risks.","PeriodicalId":10626,"journal":{"name":"Congenital Anomalies","volume":"64 5","pages":"199-206"},"PeriodicalIF":1.3,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cga.12577","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frequency of gastroschisis and omphalocele and possible influence of maternal folic acid supplementation. A narrative review 胃畸形和卵圆畸形的发病率以及母体补充叶酸可能产生的影响。综述。

IF 1.3 4区医学

Congenital Anomalies Pub Date : 2024-06-19 DOI: 10.1111/cga.12576

Laura González-Ramos, Elena Martínez-Sanz, Moisés García-Serradilla, Miquel García-de-Pereda, Estela Maldonado

{"title":"Frequency of gastroschisis and omphalocele and possible influence of maternal folic acid supplementation. A narrative review","authors":"Laura González-Ramos, Elena Martínez-Sanz, Moisés García-Serradilla, Miquel García-de-Pereda, Estela Maldonado","doi":"10.1111/cga.12576","DOIUrl":"10.1111/cga.12576","url":null,"abstract":"There is an increase in the worldwide prevalence of congenital abdominal wall defects (CAWD), with gastroschisis (GS) and omphalocele (OC) being the most common. It is widely accepted that folic acid supplementation (FAS) in the maternal diet decreases the incidence of anomalies such as neural tube defects, but there is controversy regarding the possible beneficial role for other congenital malformations. Several epidemiological studies raise controversy regarding a possible relationship between vitamin supplementation with the occurrence of abdominal wall malformations. The aim of the present study is to obtain an updated review of the global frequency of CAWD in neonates and the relationship with FAS in the mothers. For this we have carried out a systematic search of epidemiological studies in different article databases between 2011 and 2022. The analysis of 25 studies conducted in different countries where cases of OC and/or GS are registered directly or together with other congenital defects shows that 60% inquire into the relationship of FAS with the incidence of CAWD. Half of them proposes a beneficial effect of FAS and the other half find no association, concluding that there is no unanimous evidence that FAS in the maternal diet decreases the incidence of CAWD. However, it seems that an influential factor to take into account is the nutritional habits of the mothers.","PeriodicalId":10626,"journal":{"name":"Congenital Anomalies","volume":"64 5","pages":"190-198"},"PeriodicalIF":1.3,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cga.12576","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141428564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to “An easy-to-use semi-automatic volumetric evaluation for secondary bone grafting in patients with unilateral alveolar cleft” 更正 "单侧牙槽骨裂患者二次植骨的易用半自动体积评估"。

IF 1.3 4区医学

Congenital Anomalies Pub Date : 2024-06-17 DOI: 10.1111/cga.12575

引用次数: 0

Response to “An easy-to-use semi-automatic volumetric evaluation for secondary bone grafting in patients with unilateral alveolar cleft”—“Misinterpreted facial foramen” 对 "单侧牙槽骨裂患者二次植骨的简易半自动容积评估"--"被误读的面孔 "的回应

IF 1.3 4区医学

Congenital Anomalies Pub Date : 2024-05-30 DOI: 10.1111/cga.12574

Sanjanaa Kapoor, Godwin Alex Kiruba

引用次数: 0

Expectant management of pregnancy involving fetus with lower urinary tract obstruction 对患有下尿路梗阻的胎儿进行孕期管理。

IF 1.3 4区医学

Congenital Anomalies Pub Date : 2024-05-15 DOI: 10.1111/cga.12572

Takao Kobayashi, Sota Iwatani, Hitomi Mimura, Seiji Yoshimoto

引用次数: 0

Upper airway obstruction due to congenital epiglottic cyst: Report of two cases 先天性会厌囊肿导致上气道阻塞：两个病例的报告。

IF 1.3 4区医学

Congenital Anomalies Pub Date : 2024-05-08 DOI: 10.1111/cga.12571

Kensuke Uraguchi, Yuichiro Otsuka, Hidenori Marunaka, Mizuo Ando

引用次数: 0

Long-term follow-up for the atypical radial longitudinal deficiency: A case report 非典型桡骨纵向缺损的长期随访：病例报告。

IF 1.3 4区医学

Congenital Anomalies Pub Date : 2024-04-25 DOI: 10.1111/cga.12570

Hiroshi Satake, Ryuji Takeuchi, Yasushi Naganuma, Toshiya Nito, Naomi Hanaka, Junichiro Shibuya, Masahiro Maruyama, Ryusuke Honma, Michiaki Takagi

引用次数: 0

A novel variant in IFT122 associated with a severe phenotype of cranioectodermal dysplasia 与颅骨外胚层发育不良严重表型相关的 IFT122 新变体

IF 1.3 4区医学

Congenital Anomalies Pub Date : 2024-04-18 DOI: 10.1111/cga.12569

Shiho Nagayama, Hironori Takahashi, Fuyuki Hasegawa, Asuka Hori, Sho Kizami, Rieko Furukawa, Kenji Horie, Manabu Ogoyama, Kenichiro Hata, Hiroyuki Fujiwara

引用次数: 0

Ultrasound and magnetic resonance imaging features of fetal urogenital anomalies: A pictorial essay 胎儿泌尿生殖系统畸形的超声和磁共振成像特征：图解文章

IF 1.3 4区医学

Congenital Anomalies Pub Date : 2024-04-08 DOI: 10.1111/cga.12568

Behnaz Moradi, Mohammad Hossein Golezar, Reihaneh Mortazavi Ardestani, Sara Hassanzadeh, Payam Jannatdoust, Masoumeh Banihashemian, Nasim Batavani

引用次数: 0

Assisted reproduction and congenital malformations: A systematic review and meta-analysis 辅助生殖与先天性畸形：系统回顾和荟萃分析

IF 1.3 4区医学

Congenital Anomalies Pub Date : 2024-04-05 DOI: 10.1111/cga.12561

Meenakshi Veeramani, Neerujah Balachandren, Yong Hwa Hong, Jiyoon Lee, Antonio F. Corno, Dimitrios Mavrelos, Stavroula L. Kastora

{"title":"Assisted reproduction and congenital malformations: A systematic review and meta-analysis","authors":"Meenakshi Veeramani, Neerujah Balachandren, Yong Hwa Hong, Jiyoon Lee, Antonio F. Corno, Dimitrios Mavrelos, Stavroula L. Kastora","doi":"10.1111/cga.12561","DOIUrl":"10.1111/cga.12561","url":null,"abstract":"Prior studies have explored the links between congenital anomalies and assisted reproduction techniques, among other factors. However, it remains unclear whether a particular technique harbors an inherent risk of major congenital anomalies, either cumulatively or in an organ-specific manner. A meta-analysis was conducted using relevant studies from inception to February 2023 using six databases and two appropriate registers. Sources of heterogeneity were explored using sub-group analysis, using study weight, risk of bias and geographical location of original studies. Neonates conceived through assisted reproduction appear to have a higher risk of major congenital anomalies compared to naturally conceived neonates, OR 0.67 [95% CI 0.59, 0.76], I2 = 97%, p < 0.00001, with neonates conceived through intracytoplasmic sperm injection (ICSI) at a 9% higher chance of being affected in comparison to neonates conceived through in vitro fertilization (IVF). The increase in cardiac, gastrointestinal (GI), and neurological congenital anomalies appears to be independent of the assisted reproduction technique, while urogenital and musculoskeletal (MSK) anomalies were found to be increased in ICSI compared with IVF, OR 0.83 [95% CI 0.69, 0.98]; p = 0.03, I2 = 0%, and OR 0.65 [95% CI 0.49, 0.85]; p = 0.002, I2 = 80%, respectively. Neonates conceived using assisted reproduction techniques appear to be at higher risk of major congenital anomalies, with a higher risk attributable to conception using ICSI. The increase in cardiac, neurological, and GI congenital anomalies does not appear to be technique-specific, while the opposite held true for urogenital and MSK anomalies.","PeriodicalId":10626,"journal":{"name":"Congenital Anomalies","volume":"64 3","pages":"107-115"},"PeriodicalIF":1.3,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cga.12561","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140573932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0