Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie最新文献_第7页

Spermatogenesis of the lizard Lacerta vivipara: histological studies and amino acid sequence of a protamine lacertine 1. 活乳蜥精子发生的组织学研究及鱼精蛋白乳氨酸1的氨基酸序列。

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1996-06-01

A Martinage, A Depeiges, D Wouters, L Morel, P Sautière

引用次数: 0

The genetic code and cyclic codes. 遗传密码和循环密码。

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1996-06-01

J Demongeot, J Besson

{"title":"The genetic code and cyclic codes.","authors":"J Demongeot, J Besson","doi":"","DOIUrl":"","url":null,"abstract":"We proposed previously a cyclic code made of 22 triplets, which we now call the AB code. It is made up of the following chain: AUGGUGCCAUUCAAGACUAUGA. The letters A, U, C, G represent the classical symbols of the (purine and pyrimidine) bases of the genetic code. This chain presents the following features: (1) when it is in cyclic form, it begins with the initiation codon AUG, ends with the termination codon UGA, and it can be read triplet after triplet by choosing 1 and only 1 representative of each synonymy class in the classical degenerate genetic code made of 64 triplets. The chain, therefore, possesses 1 and only 1 codon for each amino-acid; (2) except for the doublet CG, triplets of the chain begin with the 15 other possible doublets of bases (satisfying the \"wobble\" hypothesis presented by Crick); (3) it corresponds (except for 1 base) to the \"loop\" part of the CEnothera mitochondrial Gly-tRNA; (4) it can be modified, without loss of the properties (1) and (2), in such a way as to have 15 bases in common with the loop part of other mitochondrial tRNA's considered as primitive, like Ala-, Pro- and Arg-tRNA; (5) it contains the most frequent triplets, but not the most rare ones, appearing in the genome of numerous species; (6) it exhibits a coherent internal structure with respect to the molecular weight of its triplets. This structure, also found in the loop part of mitochondrial tRNA's, contains an excess of AU bases with respect to GC bases. This fact has no explanation in the classical probabilistic model of the tRNA's. Therefore, we propose the cyclic AB code as a primitive genetic structure with the essential coding properties of the present genetic code.","PeriodicalId":10555,"journal":{"name":"Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie","volume":"319 6","pages":"443-51"},"PeriodicalIF":0.0,"publicationDate":"1996-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19846073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Partial sequence of the shrimp Penaeus notialis mitochondrial genome. 北对虾线粒体基因组的部分序列。

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1996-06-01

E Garcia-Machado, N Dennebouy, M O Suarez, J C Mounolou, M Monnerot

引用次数: 0

Horseradish peroxidase and glycosylated BSA induce nitric oxide production in murine macrophages. 辣根过氧化物酶和糖基化牛血清白蛋白诱导小鼠巨噬细胞产生一氧化氮。

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1996-06-01

S Afroun-Talantikite, J Ouazzani

引用次数: 0

[Complementarity of microscopies in the structural analysis of DNA minicircles associated to protein MC1]. [显微镜在MC1蛋白相关DNA微环结构分析中的互补性]。

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1996-06-01

E Larquet, E Le Cam, A Fourcade, F Culard, P Furrer, E Delain

引用次数: 0

Specific lipid protein interactions characterize 3 populations of clathrin coated vesicles involved in the LDL receptor traffic. 特定的脂质蛋白相互作用表征了参与LDL受体运输的网格蛋白包被囊泡的3个群体。

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1996-06-01

E Turpin, M Bomsel, C de Paillerets, A Alfsen

{"title":"Specific lipid protein interactions characterize 3 populations of clathrin coated vesicles involved in the LDL receptor traffic.","authors":"E Turpin, M Bomsel, C de Paillerets, A Alfsen","doi":"","DOIUrl":"","url":null,"abstract":"We have previously isolated 3 different populations of clathrin coated vesicles (CCV) involved in the LDL-receptor traffic in bovine adrenal cortex. We now show that each CCV type contains the transferrin-R and the CI-MPR, therefore, they provide a good model for studying the membrane organization that may govern their targeting in one of the biosynthetic, endocytic and/or recycling pathways. Transferrin--prototype of recylcing ligand--, and alpha adaptin, dynamin and the 110 kDa phosphatidylinositol-3-kinase subunit--of the trafficking machinery--were mainly detected in only 2 of the vesicle populations which could be involved in the endocytic/recycling pathway. The third population which contained larger amounts of gamma adaptin and do not carry transferrin could be involved in the biosynthetic pathway. The vesicle lipid pattern and the saturation of their fatty acyl chains were analyzed and confirmed these results. The nature of the interactions between vesicle components was then determined using several classes of detergents. Only non ionic ones could solubilize the LDL-R in a complex with either alpha or gamma adaptin. In contrast, they dissociated clathrin or beta-beta' adaptins. Taken together these results prompt us to suggest an integrated model for targeting in membrane traffic. Besides specific targeting signals carried by cargo proteins and recognized by proteins from the coat and the cytosolic trafficking machinery, lipids would play a key modulatory role. At each step in the membrane traffic, the proteins which carry multiple targeting signals would interact transiently with a specific set of lipids. This would result in the exposure of the appropriate targeting signals which could now become recognized by the proper targeting machinery.","PeriodicalId":10555,"journal":{"name":"Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie","volume":"319 6","pages":"493-503"},"PeriodicalIF":0.0,"publicationDate":"1996-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19847950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulse exposure to ionizing radiation elicits rapid changes in cellular radiosensitivity. 脉冲暴露于电离辐射引起细胞放射敏感性的快速变化。

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1996-06-01

V Ponette, N Giocanti, H Tourbez, J Balosso, C Hennequin, V Favaudon

{"title":"Pulse exposure to ionizing radiation elicits rapid changes in cellular radiosensitivity.","authors":"V Ponette, N Giocanti, H Tourbez, J Balosso, C Hennequin, V Favaudon","doi":"","DOIUrl":"","url":null,"abstract":"A linear electron accelerator, operated in a recurrent chopped mode, was used for time-resolved investigation of split-dose radiation recovery in 3 mammalian cell lines in vitro. The time intervals separating the sequential radiation exposures in this study ranged from fractions of a second to a few minutes. The primary pulse brought about rapid, synchronous oscillations of cellular radiosensitivity giving rise to a tetraphasic, W-shaped time-dependent profile whose first phase was accomplished by a large decrease of cell survival. Only the last phase correlated with sub-lethal damage repair determined by gamma-ray irradiation. The same profile was observed for the 3 cell lines investigated. However, the kinetics of the whole process varied extensively from one cell line to another. The first phase lasted 1 s only for Chinese hamster V79 fibroblasts, 6 s for human squamous carcinoma SQ20B cells, and as much as 25 s for human colon adenocarcinoma LoVo cells. The relative amplitude of this first phase grew with both the first and second radiation doses in the range explored. It is hypothesized that rapid oscillation of the cytotoxic potential of radiation may result from various mechanisms such as molecular recognition of radio-induced lesions, changes in chromatin structure, or differential activation of phospholipid-dependent transduction pathways.","PeriodicalId":10555,"journal":{"name":"Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie","volume":"319 6","pages":"505-9"},"PeriodicalIF":0.0,"publicationDate":"1996-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19847951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is there a human [psi]? 有人类吗?

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1996-06-01

O Jean-Jean, X Le Goff, M Philippe

引用次数: 0

House mouse ancestor from late Pliocene Siwalik sediments of India. 上新世晚期印度Siwalik沉积物中的家鼠祖先。

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1996-05-01

R Patnaik, J C Auffray, J J Jaeger, A Sahni

引用次数: 0

On the mechanisms of thymic epithelium induced tolerance. 胸腺上皮诱导耐受的机制研究。

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1996-05-01

V Thomas-Vaslin, M Coltey, J Salaün

{"title":"On the mechanisms of thymic epithelium induced tolerance.","authors":"V Thomas-Vaslin, M Coltey, J Salaün","doi":"","DOIUrl":"","url":null,"abstract":"We have devised a model in which nude mice are T cell reconstituted at birth by subcutaneous grafts of embryonic thymic epithelium (TE) removed from 10 days allogeneic embryos. The TE is colonized by the nude mouse hemopoietic cells which differentiate into T cells. Such T cell-reconstituted nude mice are able to reject third party skin graft and are tolerant to skin of their own haplotype but also the TE H-2 type. We have recently shown that this tolerance can be transferred by CD4+ peripheral T cells selected on the allogeneic TE. The question as to whether such T cells can regulate the activity of effector cells from normal mice is addressed here. We show that the transfer of peripheral T cells issued from such chimeras, together with syngeneic T cells from normal mice, into nude recipients induces a significant delay in the rejection of skin graft of the TE haplotype. This delay depends on the ratio of the 2 types of injected cells. This demonstrates that regulatory T cells selected on an allogeneic TE are able to control the effector activity of peripheral T cells issued from normal mice. The T cells selected on the allogeneic TE can therefore be considered as endowed with a negative regulatory activity with respect to the process leading to effector cells activation.","PeriodicalId":10555,"journal":{"name":"Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie","volume":"319 5","pages":"401-4"},"PeriodicalIF":0.0,"publicationDate":"1996-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19736065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0