Journal of Bangladesh College of Physicians and Surgeons最新文献

{"title":"A case of unhealing skin ulcer with iatrogenic Cushing’s syndrome","authors":"Shrebash Paul, Hashiba Moontaha, Bikash Kumar Sarkar, Sanzida Khan, Majeda Khanam, Md Zobaer Ahmed, Ariful Basher","doi":"10.3329/jbcps.v41i4.68950","DOIUrl":"https://doi.org/10.3329/jbcps.v41i4.68950","url":null,"abstract":"Cutaneous Leishmaniasis is a rare disease in South-East Asian countries like Bangladesh, often presenting as skin lesions, ulcers or granulomatous plaques on the arm or back. As the disease is uncommon, high index of suspicion is required for the diagnosis. We are presenting a case of cutaneous Leishmaniasis in a migrant Bangladeshi worker in the Kingdom of Saudi Arabia (KSA). The case was initially treated with antibiotics, emollients and systemic steroid for a long time. However, the disease progressed, and the patient developed features of iatrogenic Cushing syndrome. The diagnosis was confirmed with a skin biopsy, which revealed Leishmania parasite. He received treatment with Injectable liposomal Amphotericin B (LAmB) and oral Miltefosine with promising clinical response. Clinicians should be vigilant while treating non-healing ulcers, and consider CL when there is history of travelling to CL endemic areas J Bangladesh Coll Phys Surg 2023; 41(4): 334-337","PeriodicalId":105305,"journal":{"name":"Journal of Bangladesh College of Physicians and Surgeons","volume":"67 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134908131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demography, Clinical Profile and Outcome of COVID-19 Patients in the east-southern region of Bangladesh","authors":"Mohammad Izazul Hoque, Al Amin, Najnin Jahan Hafsa, Roksana Akter, Pinki Shaha, Utshab Roy, Md Nazmul Hasan, Abu Mohammad Saem","doi":"10.3329/jbcps.v41i4.68940","DOIUrl":"https://doi.org/10.3329/jbcps.v41i4.68940","url":null,"abstract":"Introduction: In Bangladesh, the first confirmed case of COVID-19 was detected on March 8 2020, about 3 months after the initial outbreak in late December 2019 in Wuhan, China. Both affected cases and deaths have increased exponentially during this global pandemic. Demographic and clinical data on COVID-19 in Bangladesh is still deficient. Our study aims to evaluate the demographic, clinical profile and outcome of COVID-19 Patients in the east-southern region of Bangladesh. Methodology: It was a cross sectional study. All RT-PCRpositive patients who tested in the RT-PCR lab of Comilla Medical College on 10 days of each month from July to December 2020 were included in this study. Ten days in each month were selected by lottery. After getting the verbal consent, selected patients were interviewed over the telephone by the investigator team, and their information was recorded accordingly in a preformed data sheet. Results: A total of 606 COVID-19 RT-PCR-positive patients were interviewed. The mean age was 40.39 ± 15.42 years; 62.8% were male, and 17.3% of patients had positive contact history with COVID-19 patients. Predominant presenting symptoms were fever (71.8%), cough (41.3%), breathlessness (22.8%), fatigue (18.3%), anorexia (26%) and diarrhea (4.1%). Hypertension (13.1%), diabetes mellitus (16.1%), ischemic heart disease (IHD) (2.8%) and chronic kidney disease (CKD) (0.4%) were frequent comorbidities. 72% of the patients were mild, 16% moderate , 7% severe, and 5% critically ill. 78% took home treatment and 5% were in ICU. 97.2% recovered and 2.8% died. Older age (p= 0.001), male sex (p= 0.007), smoking (p= 0.001), breathlessness (p=0.001) and presence of comorbidities (p= < 0.05) were significantly associated with mortality. 33.8% had post- COVID symptoms, including fatigue 26.7% and shortness of breath 13.2%. Conclusion: Younger age groups were more affected than older age groups. Majority of the patients did not have a history of contact with COVID-19 patients. Most of the patients had mild symptoms. About one fourth were hospitalized, among them 5% got treatment in ICU. Most of the patients recovered, and 2.8% died. Death was more common in patients with multiple comorbidities. One third of recovered patients had post-COVID symptoms. J Bangladesh Coll Phys Surg 2023; 41(4): 298-304","PeriodicalId":105305,"journal":{"name":"Journal of Bangladesh College of Physicians and Surgeons","volume":"34 17","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136382044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disease Severity and Clinical Outcome of Coronavirus Vaccinated Patients Following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection","authors":"Nirmal Kanti Sarkar, Moumita Roy, Salahuddin Feroz, Md Ashadur Rahman","doi":"10.3329/jbcps.v41i4.68928","DOIUrl":"https://doi.org/10.3329/jbcps.v41i4.68928","url":null,"abstract":"Background and aims: The severity of illness and mortality in coronavirus disease (COVID-19) may be curtailed byvaccination. We assessed the disease severity and clinical outcome in coronavirus vaccinated patients following SARSCoV-2 infection. Methods: We conducted an observational study among theSARS-CoV-2 infected patients who received one or two doses of a single generic type of coronavirus vaccine (ChAdOx1nCoV-19, Covishield®, Serum Institute of India) at the outset of vaccine rollout program in Bangladesh. Eligible patients treated at home, outpatient basis, or hospitalized between April 10, 2021, and June 18, 2021, were included. Demographic characteristics, clinical presentation, comorbidities, radiological features, disease severity, treatment protocol, and outcomes were evaluated. The primary end point was disease severity (mild, moderate, severe, and critical).The secondary endpoint was clinical outcome (complete recovery or death) at day 28. Results: The cohort included total 61 patients. Age ranged between 23–82 year; majority were male (62.3%). Ninety-five percent patients received a single dose of vaccine. Most of the patients had mild symptoms (63.9%), and treated at home (67.2%). Most of the patients recovered utterly (95.1%) without any death. Vaccination showed reduced disease severity (RR 0.93, 95% CI, 0.87-0.99). Conclusions: In this study it was observed that coronavirus vaccine may significantly lessen disease severity, improve clinical outcome, and prevent death among SARS-CoV-2infected patients. J Bangladesh Coll Phys Surg 2023; 41(4): 294-297","PeriodicalId":105305,"journal":{"name":"Journal of Bangladesh College of Physicians and Surgeons","volume":"43 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134908994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Potentially Malignant Disorders: A review on Bangladesh perspective","authors":"Mushfiq Hassan Shaikh, Md Ashif Iqbal, SM Anwar Sadat","doi":"10.3329/jbcps.v41i4.66936","DOIUrl":"https://doi.org/10.3329/jbcps.v41i4.66936","url":null,"abstract":"Oral potentially malignant disorders (OPMDs) are a group of chronic conditions affecting the oral mucosa with a risk of transformation to oral squamous cell carcinoma (OSCC). Oral leukoplakia, oral submucous fibrosis, oral lichen planus, and oral erythroplakia are the most common OPMDs observed in South Asian population. However, oral leukoplakia and oral lichen planus are commonly encountered OPMDs in clinical practice in Bangladesh, possibly, owing to specific lifestyle habits. Although the exact aetiology is unknown, use of smokeless tobacco, smoking, and chewing of betel quid containing areca nut, are considered as common risk factors for OPMDs. Early diagnosis is very important and can be lifesaving, as at a late stage, OPMDs are more likely to progress into severe dysplasia or even into squamous cell carcinoma. In fact, OPMDs have a significantly increased risk of progressing to cancer, mostly in South Asian population, including Bangladesh. This review provides an overview of the OPMDs in Bangladeshi population. J Bangladesh Coll Phys Surg 2023; 41(4): 305-314","PeriodicalId":105305,"journal":{"name":"Journal of Bangladesh College of Physicians and Surgeons","volume":"25 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134908535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diversity of upper respiratory tract pathogens in patients having flu-like symptoms during Covid-19 pandemic in a referral hospital","authors":"Md Mizanur Rahman, KFM Ayaz, Sadiqul Islam, Nazmul Hasan, Rummana Rahim, Abu Hasan","doi":"10.3329/jbcps.v41i4.68922","DOIUrl":"https://doi.org/10.3329/jbcps.v41i4.68922","url":null,"abstract":"Background: Upper respiratory tract infections (URTIs) are caused by a wide range of viruses and bacteria, however, produce similar symptoms. Routine molecular tests are not performed and empirical use of antibiotics in treating URTIs is a major public health concern. In attempt to unveil the diversity of upper respiratory tract pathogens in the community during COVID-19 pandemic, we have screened 153 nasopharyngeal swab samples from patients having flu like symptoms. Materials and methods: We tested nasopharyngeal swabs by real-time multiplex PCR for 19 viruses and 3 bacteria using cartridge based rapid PCR platform. Results: Of 153 patients sample tested, 103 (67.32%) had a laboratory-confirmed respiratory pathogen. Of the 153 swabs tested rhinovirus/enterovirus was found 25(16.34%), influenza 18(11.77%), RSV 13(8.5%), SARS-CoV2- 15(11.11%), other coronaviruses 11(7.19%), parainfluenza 16(10.45%), human metapneumovirus 8(5.23%). Out of 18 influenza cases influenza A was 17(11.12%) and influenza B was 1(0.65%). Among 17 influenza A viruses H1N1pdm09 strain was 9(5.88%), H3 was 5(3.27%). These data shows that even in COVID-19 pandemic period rhinovirus/ enterovirus and Influenza dominated over all other respiratory viruses and as a causative agent bacteria might play very insignificant role in URTIs. Conclusion: Our data provides strong evidence against empiric antibiotic use for treating URTIs and highlights a strong need for improving the diagnostic capacity for URTIs by using more molecular testing in the country. J Bangladesh Coll Phys Surg 2023; 41(4): 256-261","PeriodicalId":105305,"journal":{"name":"Journal of Bangladesh College of Physicians and Surgeons","volume":"124 1-2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134909003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Johann Friedrich August von Esmarch – the Father of First Aid surgery","authors":"Kaushik Bhattacharya, Neela Bhattacharya","doi":"10.3329/jbcps.v41i3.66935","DOIUrl":"https://doi.org/10.3329/jbcps.v41i3.66935","url":null,"abstract":"Regarded as the Father of First Aid and surgical haemostasis for the war wounded soldiers, Johann Friedrich August von Esmarch was one of the greatest military surgeons ever born. His contributions range from devising his own illustrated bandage to application of tourniquet to prevent blood loss in trauma victims in the battlefield. He has also invented an inhalation mask for chloroform anesthesia, splints and surgical instruments. He changed the way the war wounds were managed and made many serious war injured victims go home alive J Bangladesh Coll Phys Surg 2023; 41: 244-247","PeriodicalId":105305,"journal":{"name":"Journal of Bangladesh College of Physicians and Surgeons","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135702558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}