Clinical Hypertension最新文献

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The association between arterial stiffness and socioeconomic status: a cross-sectional study using estimated pulse wave velocity. 动脉僵化与社会经济地位之间的关系:一项利用估计脉搏波速度进行的横断面研究。
IF 2.6
Clinical Hypertension Pub Date : 2024-10-01 DOI: 10.1186/s40885-024-00284-7
Hack-Lyoung Kim, Soonil Kwon, Hyun Sung Joh, Woo-Hyun Lim, Jae-Bin Seo, Sang-Hyun Kim, Joo-Hee Zo, Myung-A Kim
{"title":"The association between arterial stiffness and socioeconomic status: a cross-sectional study using estimated pulse wave velocity.","authors":"Hack-Lyoung Kim, Soonil Kwon, Hyun Sung Joh, Woo-Hyun Lim, Jae-Bin Seo, Sang-Hyun Kim, Joo-Hee Zo, Myung-A Kim","doi":"10.1186/s40885-024-00284-7","DOIUrl":"10.1186/s40885-024-00284-7","url":null,"abstract":"<p><strong>Background: </strong>The impact of socioeconomic status (SES) on arterial stiffness remains unclear. This study aimed to explore the association between both personal and household income, as well as education level, and estimated pulse wave velocity (ePWV).</p><p><strong>Methods: </strong>A total of 13,539 participants (mean age 52.9 ± 16.7 years; 57.1% women) from the Korean National Health and Nutrition Survey database were analyzed. For SES variables, information on personal and household income and education level was collected using standardized questionnaires.</p><p><strong>Results: </strong>The ePWV did not show significant differences across groups categorized by individual income levels (P = 0.183). However, there was a noticeable trend of decreasing ePWV with increasing household income levels (P < 0.001). Additionally, ePWV demonstrated a significant negative correlation with higher education levels, indicating that ePWV decreased in groups with higher educational attainment (P < 0.001). In multiple linear regression analyses, both household income (β = -0.055; P < 0.001) and education level (β = -0.076; P < 0.001) were negatively associated with ePWV, even after adjusting for potential confounders.</p><p><strong>Conclusions: </strong>Lower household income and lower education levels were associated with higher ePWV, providing further evidence of the influence of SES on arterial stiffness.</p>","PeriodicalId":10480,"journal":{"name":"Clinical Hypertension","volume":"30 1","pages":"26"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11443864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic periodontal disease is related with newly developing hypertension: a nationwide cohort study. 慢性牙周病与新发高血压的关系:一项全国性队列研究。
IF 2.6
Clinical Hypertension Pub Date : 2024-10-01 DOI: 10.1186/s40885-024-00285-6
Jung-Hyun Park, Min Kyoung Kang, Gwang Hyun Leem, Jin-Woo Kim, Tae-Jin Song
{"title":"Chronic periodontal disease is related with newly developing hypertension: a nationwide cohort study.","authors":"Jung-Hyun Park, Min Kyoung Kang, Gwang Hyun Leem, Jin-Woo Kim, Tae-Jin Song","doi":"10.1186/s40885-024-00285-6","DOIUrl":"10.1186/s40885-024-00285-6","url":null,"abstract":"<p><strong>Background: </strong>Periodontal disease (PD) is a condition that can be treated and managed. This study aimed to determine if chronic PD status is associated with the risk of developing hypertension, utilizing data from the National Health Insurance Database of Korea.</p><p><strong>Methods: </strong>Participants who received oral health examinations both in 2003 and in 2005-2006 were included. Those with a history of hypertension were excluded. Hypertension was defined as at least one outpatient or inpatient claim diagnosis (primary or secondary) of hypertension (International Classification of Diseases (ICD)-10 codes I10-I11) with prescription for antihypertensive medication or at least one incident of systolic blood pressure greater than 140 mmHg or diastolic blood pressure greater than 90 mmHg during a health examination. Changes of PD status was determined during two oral examinations. Study participants were divided into 4 groups according to the changes of PD status: PD-free (those consistently free of disease in both exams), PD-recovered (individuals with disease initially but not in the second exam), PD-developed (no disease initially, but present in the second exam), and PD-chronic (disease throughout both exams). The incidence of hypertension after the second oral health examination (index date) was monitored. Participants were observed from the index date until the earliest occurrence of hypertension onset, mortality, or December 2020.</p><p><strong>Results: </strong>The study comprised 706,584 participants: 253,003(35.8%) in the PD-free group, 140,143(19.8%) in the PD-recovered group, 132,397(18.7%) in the PD-developed group, and 181,041(25.6%) in the PD-chronic group. Over a median follow-up duration of 14.3 years, 239,937 (34.0%) cases of hypertension were recorded. The PD-recovered group had a lower risk of hypertension compared to the PD-chronic group, while the PD-developed group had a higher risk of hypertension compared to the PD-free group.</p><p><strong>Conclusion: </strong>Chronic PD is associated with an increased risk of developing hypertension. Although the increase in risk is modest, recovery from PD may have beneficial effects in reducing hypertension risk. Further studies are needed to confirm the importance of regular dental examinations and effective management of PD to reduce hypertension risk.</p>","PeriodicalId":10480,"journal":{"name":"Clinical Hypertension","volume":"30 1","pages":"27"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11443627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of glucagon-like peptide-1 receptor agonists (GLP1-RAs) in the management of the hypertensive patient with metabolic syndrome: a position paper from the Korean society of hypertension. 胰高血糖素样肽-1 受体激动剂(GLP1-RAs)在代谢综合征高血压患者治疗中的作用:韩国高血压学会的立场文件。
IF 2.6
Clinical Hypertension Pub Date : 2024-09-01 DOI: 10.1186/s40885-024-00279-4
Hae Young Lee, Seung-Hyun Ko, Sungjoon Park, Kyuho Kim, Song-Yi Kim, In-Jeong Cho, Eun Joo Cho, Hyeon Chang Kim, Jae-Hyeong Park, Sung Kee Ryu, Min Kyong Moon, Sang-Hyun Ihm
{"title":"The role of glucagon-like peptide-1 receptor agonists (GLP1-RAs) in the management of the hypertensive patient with metabolic syndrome: a position paper from the Korean society of hypertension.","authors":"Hae Young Lee, Seung-Hyun Ko, Sungjoon Park, Kyuho Kim, Song-Yi Kim, In-Jeong Cho, Eun Joo Cho, Hyeon Chang Kim, Jae-Hyeong Park, Sung Kee Ryu, Min Kyong Moon, Sang-Hyun Ihm","doi":"10.1186/s40885-024-00279-4","DOIUrl":"10.1186/s40885-024-00279-4","url":null,"abstract":"<p><p>Obesity is the one of the most important components of metabolic syndrome. Because obesity related hypertension accounts for two thirds of essential hypertension, managing obesity and metabolic syndrome is a crucial task in the management of hypertension. However, the current non-pharmacological therapies have limitations for achieving or maintaining ideal body weight. Recently, glucagon-like peptide-1 receptor agonists (GLP1-RAs) have demonstrated excellent weight control effects, accompanied by corresponding reductions in blood pressure. GLP1-RAs have shown cardiovascular and renal protective effects in cardiovascular outcome trials both in primary and secondary prevention. In this document, the Korean Society of Hypertension intends to remark the current clinical results of GLP1-RAs and recommend the government and health-policy makers to define obesity as a disease and to establish forward-looking policies for GLP1-RA treatment for obesity treatment, including active reimbursement policies.</p>","PeriodicalId":10480,"journal":{"name":"Clinical Hypertension","volume":"30 1","pages":"24"},"PeriodicalIF":2.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obesity and hypertension in children and adolescents. 儿童和青少年的肥胖症和高血压。
IF 2.6
Clinical Hypertension Pub Date : 2024-09-01 DOI: 10.1186/s40885-024-00278-5
Soo In Jeong, Sung Hye Kim
{"title":"Obesity and hypertension in children and adolescents.","authors":"Soo In Jeong, Sung Hye Kim","doi":"10.1186/s40885-024-00278-5","DOIUrl":"10.1186/s40885-024-00278-5","url":null,"abstract":"<p><p>As childhood obesity rates increase worldwide, the prevalence of obesity-related hypertension is also on the rise. Obesity has been identified as a significant risk factor for hypertension in this age group. National Health Surveys and meta-analyses show increasing trends in obesity and pediatric hypertension in obese children. The diagnosis of hypertension in children involves percentiles relative to age, sex, and height, unlike in adults, where absolute values are considered. Elevated blood pressure (BP) in childhood is consistently associated with cardiovascular disease in adulthood, emphasizing the need for early detection and intervention. The pathogenesis of hypertension in obesity involves multiple factors, including increased sympathetic nervous system activity, activation of the renin-angiotensin-aldosterone system (RAAS), and renal compression due to fat accumulation. Obesity disrupts normal RAAS suppression and contributes to impaired pressure natriuresis and sodium retention, which are critical factors in the development of hypertension. Risk factors for hypertension in obesity include degree, duration, and distribution of obesity, patient age, hormonal changes during puberty, high-sodium diet, sedentary lifestyle, and socioeconomic status. Treatment involves lifestyle changes, with weight loss being crucial to lowering BP. Medications such as angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers may be considered first, and surgical approaches may be an option for severe obesity, requiring tailored antihypertensive medications that consider individual pathophysiology to avoid exacerbating insulin resistance and dyslipidemia.</p>","PeriodicalId":10480,"journal":{"name":"Clinical Hypertension","volume":"30 1","pages":"23"},"PeriodicalIF":2.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic value of the triglyceride-glucose index for adverse cardiovascular outcomes in young adult hypertension. 甘油三酯-葡萄糖指数对年轻成人高血压心血管不良后果的预测价值。
IF 2.6
Clinical Hypertension Pub Date : 2024-09-01 DOI: 10.1186/s40885-024-00274-9
Chen Li, Yu Zhang, Xueyi Wu, Kai Liu, Wei Wang, Ying Qin, Wenjun Ma, Huimin Zhang, Jizheng Wang, Yubao Zou, Lei Song
{"title":"Prognostic value of the triglyceride-glucose index for adverse cardiovascular outcomes in young adult hypertension.","authors":"Chen Li, Yu Zhang, Xueyi Wu, Kai Liu, Wei Wang, Ying Qin, Wenjun Ma, Huimin Zhang, Jizheng Wang, Yubao Zou, Lei Song","doi":"10.1186/s40885-024-00274-9","DOIUrl":"10.1186/s40885-024-00274-9","url":null,"abstract":"<p><strong>Background: </strong>The triglyceride-glucose (TyG) index is a reliable marker of insulin resistance that is involved in the progression of hypertension. This study aimed to evaluate the association of the TyG index with the risk for major cardiovascular events (MACE) in young adult hypertension.</p><p><strong>Methods: </strong>A total of 2,651 hypertensive patients aged 18-40 years were consecutively enrolled in this study. The TyG index was calculated as Ln [triglycerides × fasting plasma glucose/2]. The cutoff value for an elevated TyG index was determined to be 8.43 by receiver-operating characteristic curve analysis. The primary endpoint was MACE, which was a composite of all-cause death, non-fatal myocardial infarction, coronary revascularization, non-fatal stroke, and end-stage renal dysfunction. The secondary endpoints were individual MACE components.</p><p><strong>Results: </strong>During the median follow-up time of 2.6 years, an elevated TyG index was associated with markedly increased risk of MACE (adjusted hazard ratio [HR] 3.440, P < 0.001) in young hypertensive adults. In subgroup analysis, the elevated TyG index predicted an even higher risk of MACE in women than men (adjusted HR 6.329 in women vs. adjusted HR 2.762 in men, P for interaction, 0.001); and in patients with grade 2 (adjusted HR 3.385) or grade 3 (adjusted HR 4.168) of hypertension than those with grade 1 (P for interaction, 0.024). Moreover, adding the elevated TyG index into a recalibrated Systematic COronary Risk Evaluation 2 model improved its ability to predict MACE.</p><p><strong>Conclusions: </strong>An elevated TyG index is associated with a higher risk of MACE in young adult hypertension, particularly in women and those with advanced hypertension. Regular evaluation of the TyG index facilitates the identification of high-risk patients.</p>","PeriodicalId":10480,"journal":{"name":"Clinical Hypertension","volume":"30 1","pages":"25"},"PeriodicalIF":2.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term outcomes of percutaneous transluminal renal artery intervention: a retrospective study at a single center. 经皮腔内肾动脉介入治疗的长期疗效:单个中心的回顾性研究。
IF 2.6
Clinical Hypertension Pub Date : 2024-08-01 DOI: 10.1186/s40885-024-00282-9
In Sook Kang, Donghoon Choi, Young-Guk Ko, Dong-Ho Shin, Jung-Sun Kim, Byeong-Keuk Kim, Myeong-Ki Hong, Yangsoo Jang
{"title":"Long-term outcomes of percutaneous transluminal renal artery intervention: a retrospective study at a single center.","authors":"In Sook Kang, Donghoon Choi, Young-Guk Ko, Dong-Ho Shin, Jung-Sun Kim, Byeong-Keuk Kim, Myeong-Ki Hong, Yangsoo Jang","doi":"10.1186/s40885-024-00282-9","DOIUrl":"10.1186/s40885-024-00282-9","url":null,"abstract":"<p><strong>Background: </strong>The indications, benefits, and outcomes of percutaneous transluminal renal artery intervention (PTRI) remain controversial. The study purpose was to evaluate the long-term outcomes of PTRI in clinical practice.</p><p><strong>Methods: </strong>A retrospective review of 217 subjects (254 renal arteries; mean age, 59.8 years) who underwent PTRI based on medical database.</p><p><strong>Results: </strong>The most common cause of renal artery stenosis was atherosclerosis in 217 (85.4%), followed by Takayasu arteritis (TA) in 23 (9.1%), fibromuscular dysplasia in five (2.0%) and others in nine (3.5%). Mean follow-up duration was 5.7 ± 3.7 years. The first restenosis rate was 7.5% (n = 19; highest in TA: n = 9, 47.4%) and second restenosis occurred in six arteries (five TAs, one fibromuscular dysplasia). Follow-up blood pressure improved from 142.0/83.5 to 122.8/73.5 mmHg (P < 0.001). There was no change within 5 years' follow-up in estimated glomerular filtration rate (P = 0.44), whereas TA changed from 69.8 ± 20.5 to 84.2 ± 17.9 mL/min/1.73 m² (P = 0.008). Progressive renal dysfunction was related to diabetes mellitus, chronic kidney disease, and peripheral artery obstructive disease on multivariate analysis with hazard ratios (95% confidence intervals) of 2.24 (1.21-4.17), 2.54 (1.33-4.84), and 3.93 (1.97-7.82), respectively.</p><p><strong>Conclusions: </strong>PTRI was associated with a blood pressure reduction. Despite a higher rate of restenosis, patients with TA showed significant improvement in estimated glomerular filtration rate. Diabetes mellitus, chronic kidney disease, and peripheral artery obstructive disease were related with progressive renal dysfunction after PTRI.</p>","PeriodicalId":10480,"journal":{"name":"Clinical Hypertension","volume":"30 1","pages":"21"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11293128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obstructive sleep apnea and hypertension; critical overview. 阻塞性睡眠呼吸暂停与高血压;重要概述。
IF 2.6
Clinical Hypertension Pub Date : 2024-08-01 DOI: 10.1186/s40885-024-00276-7
Younghoon Kwon, William S Tzeng, Jiwon Seo, Jeongok Gang Logan, Marijana Tadic, Gen-Min Lin, Miguel Angel Martinez-Garcia, Martino Pengo, Xiaoyue Liu, Yeilim Cho, Luciano F Drager, William Healy, Geu-Ru Hong
{"title":"Obstructive sleep apnea and hypertension; critical overview.","authors":"Younghoon Kwon, William S Tzeng, Jiwon Seo, Jeongok Gang Logan, Marijana Tadic, Gen-Min Lin, Miguel Angel Martinez-Garcia, Martino Pengo, Xiaoyue Liu, Yeilim Cho, Luciano F Drager, William Healy, Geu-Ru Hong","doi":"10.1186/s40885-024-00276-7","DOIUrl":"10.1186/s40885-024-00276-7","url":null,"abstract":"<p><p>Obstructive sleep apnea (OSA) and hypertension are two important modifiable risk factors for cardiovascular disease and mortality. Numerous studies have highlighted the interplay between these two conditions. We provide a critical review of the current literature on the role of the OSA as a risk factor for hypertension and its effect on blood pressure (BP). We discuss several key topics: the effect of OSA on nocturnal BP, BP response to continuous positive airway pressure (CPAP) treatment, CPAP effect on BP in refractory hypertension, the role of OSA in BP variability (BPV), and maladaptive cardiac remodeling mediated by OSA's effect on BP. Finally, we discuss the unique aspects of ethnicity and social determinants of health on OSA with a focus on Asian populations and the disparity in BP control and cardiovascular outcomes.</p>","PeriodicalId":10480,"journal":{"name":"Clinical Hypertension","volume":"30 1","pages":"19"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11293186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blood pressure control in diabetic kidney disease: a post-hoc analysis of the FANTASTIC trial. 糖尿病肾病患者的血压控制:FANTASTIC 试验的事后分析。
IF 2.6
Clinical Hypertension Pub Date : 2024-08-01 DOI: 10.1186/s40885-024-00280-x
Cheol Ho Park, Soon Jun Hong, Sung Gyun Kim, Seok Joon Shin, Dong Ki Kim, Jung Pyo Lee, Sang Youb Han, Sangho Lee, Jong Chul Won, Young Sun Kang, Jongha Park, Byoung-Geun Han, Ki-Ryang Na, Kyu Yeon Hur, Yong-Jin Kim, Sungha Park, Tae-Hyun Yoo
{"title":"Blood pressure control in diabetic kidney disease: a post-hoc analysis of the FANTASTIC trial.","authors":"Cheol Ho Park, Soon Jun Hong, Sung Gyun Kim, Seok Joon Shin, Dong Ki Kim, Jung Pyo Lee, Sang Youb Han, Sangho Lee, Jong Chul Won, Young Sun Kang, Jongha Park, Byoung-Geun Han, Ki-Ryang Na, Kyu Yeon Hur, Yong-Jin Kim, Sungha Park, Tae-Hyun Yoo","doi":"10.1186/s40885-024-00280-x","DOIUrl":"10.1186/s40885-024-00280-x","url":null,"abstract":"<p><strong>Background: </strong>The target blood pressure (BP) value is unclear for diabetic kidney disease (DKD). Therefore, we aimed to evaluate the effect of strict BP control or 'on treatment' BP on clinical outcomes in patients with DKD.</p><p><strong>Methods: </strong>A post-hoc analysis of the prespecified secondary outcomes of the FimAsartaN proTeinuriA SusTaIned reduCtion in comparison with losartan in diabetic chronic kidney disease (FANTASTIC) trial, a randomized multicenter double-blind phase III trial. Eligible patients were aged ≥ 19 years with DKD. We assigned 341 participants with DKD to BP control strategy (standard-systolic BP [SBP] < 140 mmHg versus strict-SBP < 130 mmHg). The outcome was the occurrence of cardiovascular events and renal events. Separate analyses were performed to compared the risk of outcome according to achieved average BP levels.</p><p><strong>Results: </strong>A total of 341 participants were included in the analysis. Over a median follow-up of 2.8 years, cardiovascular/renal events were observed in 25 (7.3%) participants. Mean (SD) SBPs in the standard and strict BP control group were 140.2 (11.6) and 140.2 (11.9) mmHg, respectively. The strict BP control group did not show significantly reduced risk of cardiovascular/renal events (HR 1.32; 95% CI 0.60-2.92]). In the post-hoc analyses using achieved BP, achieved average SBP of 130-139 mmHg resulted in reduced risk of cardiovascular/renal events (HR 0.15; 95% CI 0.03-0.67) compared to achieved average SBP ≥ 140 mmHg, whereas further reduction in achieved average SBP < 130 mmHg did not impart additional benefits.</p><p><strong>Conclusion: </strong>In patients with DKD, targeting a SBP of less than 130 mmHg, as compared with less than 140 mmHg, did not reduce the rate of a composite of cardiovascular and renal events. Achieved SBP of 130-139 mmHg was associated with a decreased risk for the primary outcome in patients with DKD.</p><p><strong>Trial registration: </strong>ClinicalTirals.gov Identifier: NCT02620306, registered December 3, 2015. ( https://clinicaltrials.gov/study/NCT02620306 ).</p>","PeriodicalId":10480,"journal":{"name":"Clinical Hypertension","volume":"30 1","pages":"20"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11293031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of physical activity intervention on blood pressure in 18 low and middle-income countries: a systematic review and meta-analysis of randomized controlled trials. 18 个中低收入国家体育锻炼干预对血压的影响:随机对照试验的系统回顾和荟萃分析。
IF 2.6
Clinical Hypertension Pub Date : 2024-08-01 DOI: 10.1186/s40885-024-00281-w
Vahid Monfared, Mohtaram Hashemi, Fatemeh Kiani, Reyhane Javid, Mahsa Yousefi, Mahdis Hasani, Ali Jafari, Mohammad Ali Vakili, Motahareh Hasani
{"title":"The effect of physical activity intervention on blood pressure in 18 low and middle-income countries: a systematic review and meta-analysis of randomized controlled trials.","authors":"Vahid Monfared, Mohtaram Hashemi, Fatemeh Kiani, Reyhane Javid, Mahsa Yousefi, Mahdis Hasani, Ali Jafari, Mohammad Ali Vakili, Motahareh Hasani","doi":"10.1186/s40885-024-00281-w","DOIUrl":"10.1186/s40885-024-00281-w","url":null,"abstract":"<p><strong>Background: </strong>In especially, low and middle-income nations (LMICs), where healthcare access may be restricted, high blood pressure (BP) is a major risk factor for cardiovascular disease and stroke, both of which can even lead to death. Altering one's lifestyle, in conjunction with medical therapy, has been demonstrated to be effective in lowering BP. Recent research has shown that physical activity (PA), in a variety of guises and to varying degrees, can be an effective means of lowering BP.</p><p><strong>Objective: </strong>The purpose of this meta-analysis and systematic review was to evaluate the impact that PA plays in the development of hypertension in LMICs nations.</p><p><strong>Methods: </strong>An exhaustive search of the available research was carried out in order to locate studies that were pertinent. We searched a number of online databases, such as SCOPUS, Medline, and Web of Science, looking for clinical trials that were published before March of 2023. Studies were only considered for inclusion if they were randomized controlled trials (RCTs), reported on the association between PA and BP, and were carried out in LMICs countries.</p><p><strong>Results: </strong>This meta-analysis incorporated a comprehensive collection of 60 studies, encompassing a total of 11,002 people, consisting of 5,630 cases and 5372 controls. The findings indicate that engaging in PA had a notable impact on decreasing systolic blood pressure (SBP), as seen by a weighted mean difference (WMD) of -7.70 mmHg, with a 95% confidence interval (CI) ranging from -9.50 to -5.91 (p < 0.001). Additionally, PA was found to have a significant influence on reducing diastolic blood pressure (DBP), as indicated by a WMD of -3.60 mmHg, with a 95% CI ranging from -4.48to -2.73(p < 0.001). The findings from subgroup analysis indicate that the observed results remained statistically significant when considering individuals with baseline SBP of 120 mmHg or lower and DBP of 80 mmHg or lower.</p><p><strong>Conclusion: </strong>The incorporation of PA can significantly contribute to the mitigation of high BP within LMICs nations. Additional investigation is required to ascertain the most effective form and amount of PA in order to mitigate BP levels within these specific individuals.</p>","PeriodicalId":10480,"journal":{"name":"Clinical Hypertension","volume":"30 1","pages":"22"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11293006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing blood pressure measurements between sitting in chairs and sitting on the floor. 比较坐在椅子上和坐在地板上的血压测量结果。
IF 2.6
Clinical Hypertension Pub Date : 2024-07-01 DOI: 10.1186/s40885-024-00273-w
Byung Sik Kim, Young-Hyo Lim, Woohyeun Kim, Hyungdon Kook, Jeong-Hun Shin, Yonggu Lee, Ran Heo, Hyun-Jin Kim, Jinho Shin
{"title":"Comparing blood pressure measurements between sitting in chairs and sitting on the floor.","authors":"Byung Sik Kim, Young-Hyo Lim, Woohyeun Kim, Hyungdon Kook, Jeong-Hun Shin, Yonggu Lee, Ran Heo, Hyun-Jin Kim, Jinho Shin","doi":"10.1186/s40885-024-00273-w","DOIUrl":"10.1186/s40885-024-00273-w","url":null,"abstract":"<p><strong>Background: </strong>The current standard approach to measuring home blood pressure (BP) involves taking measurements while sitting in a chair. In cultures where floor sitting is common, including Korea, assessing BP while sitting on the floor would be more feasible. However, there is still a lack of research investigating whether BP measurements obtained while seated in a chair and while sitting on the floor can be regarded as interchangeable. The aim of the study was to evaluate whether there is a difference between BP measurements taken while sitting in a chair and while sitting on the floor in a Korean adult.</p><p><strong>Methods: </strong>Among the participants who visited for evaluation of pulse wave velocity, a total of 116 participants who agreed to participate in the study were randomly selected. All subjects rested for 5 min, and BP measurements were taken at 1-min intervals according to a randomly assigned order of standard method (chair-sitting) and BP in a seated on the floor (floor-sitting).</p><p><strong>Results: </strong>Of the 116 participants, the median age was 68 (with an interquartile range of 59 to 75), and 82% were men. There were no significant differences in systolic BP (SBP, 129.1 ± 17.8 mmHg in chair-sitting and 130.1 ± 18.9 mmHg in floor-sitting, P = 0.228) and diastolic BP (DBP, 73.9 ± 11.4 mmHg in chair-sitting and 73.7 ± 11.4 mmHg in floor-sitting, P = 0.839) between the two positions. In addition, there was a high level of agreement between BP measurements taken in the two positions (intraclass correlation coefficients: 0.882 for SBP and 0.890 for DBP).</p><p><strong>Conclusion: </strong>These findings provide important insights into securing the reliability of home BP measurements through the commonly practiced floor-sitting posture in cultures where floor sitting is common. Furthermore, this could serve as substantial evidence for providing specific home BP measurement guidelines to patients who adhere to a floor-sitting lifestyle.</p>","PeriodicalId":10480,"journal":{"name":"Clinical Hypertension","volume":"30 1","pages":"16"},"PeriodicalIF":2.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11215825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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