{"title":"COVID-19 and Emerging Zoonosis - The Clock is Counting Down: Time for Closer Collaboration between Veterinary and Human Medicine","authors":"A. Coelho","doi":"10.23880/oajvsr-16000209","DOIUrl":"https://doi.org/10.23880/oajvsr-16000209","url":null,"abstract":"The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) quickly spread from China and crossed international borders. For the first time in this century, the world is facing a nightmare of 2 million deaths due to the respiratory pandemic by January 2021. Most of the emerging or re-emerging pathogens are likely to be zoonotic, and SARS-CoV-2 potentially has an animal origin, a circumstance that is a public health concern and a burden on any country’s economy. Greater awareness and understanding of potential disease promoters and effective disease surveillance systems are crucial for detecting outbreaks of emerging zoonotic diseases as quickly as possible. In order to achieve this goal, there is an urgent need for a One Health approach between human and veterinary medicine. Indeed, the One Health approach, along with all the lessons learned from previous coronavirus threats (SARS- and MERS-CoVs), as well as the advance of science is essential for dealing with emerging zoonosis, including COVID-19. It is urgent to create task forces, networks and all types of collaborations between human and veterinary medicine to prevent future pandemic events.","PeriodicalId":104363,"journal":{"name":"Open Access Journal of Veterinary Science & Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115474750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rapid and Effective Method to Prolong Pain Relief in Sheep Using Bupivacaine and Intralipid ® Combination","authors":"Farzin Sahebjam","doi":"10.23880/oajvsr-16000185","DOIUrl":"https://doi.org/10.23880/oajvsr-16000185","url":null,"abstract":"Background : To compare the duration of action of a local anesthetic block using a lipid formulation of bupivacaine to the commercially available aqueous formulation. Bupivacaine 0.5% was mixed with an equal volume of either lipid emulsion (Intralipid, Fresenius Kabi) or normal saline resulting in a final concentration of 0.25% bupivacaine. Eighteen sheep were administered a n erve block of either control or treatment at the metacarpal region of each forelimb to compare the efficacy of the injected formulations. The nociceptive test was determined by applying a blunt noxious stimulus to the foot below the nerve block at multiple time intervals until the sheep responded by withdrawing its foot. The person assessing the response to the noxious stimulus was blinded to the treatment. Results: The Intralipid formulation significantly extended the duration of the nerve block compared to the control group. The mean analgesic period (mean±SD) in the control legs was 4.23±1.8 hr. compared to 5.81±1.78 hr. in the Intralipid injected legs (p=0.013). Conclusions : In conclusion, an Intralipid® - based formulation provided a more prolonged dura tion of local anesthesia after nerve blocks in the sheep metacarpal region compared to aqueous bupivacaine.","PeriodicalId":104363,"journal":{"name":"Open Access Journal of Veterinary Science & Research","volume":"251 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116161902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiological Evaluation of Fractures Healing Processing Fixed by Food Grate Stainless Steel Rods in Rabbits","authors":"Humam H. Nazht","doi":"10.23880/oajvsr-16000189","DOIUrl":"https://doi.org/10.23880/oajvsr-16000189","url":null,"abstract":"This study was designed to follow up the radiological changes of the fracture healing process of the induced transverse femoral mid shift fracture in rabbits that fixed by food grate stainless steel rods (FGSR). Eight adult local breed rabbits were employed to induce complete transverse mid shift fracture in the femoral bone, under general anesthesia with highly aseptic technique. The fracture fragments fixed with FGSR, the study followed for more than two months by weekly radiographic examination, which revealed, the fracture healing occurs by secondary or indirect bone union, in which the new bone formation can be visible radiographically at the end of 2 nd week Post operati on (p. o.) around the fractures line which still visible, the callus formation increase in volume and density at the end of 3 rd week, at the end of 4 th weeks bony bridge formation and disappear of fracture line, at the end of the 6 th weeks radiological unio n occurs and the FGSR removed and remodeling phase started and continuous next week the conclusion the fracture healing processing of the induced fracture in the femoral bones in rabbits which fixed FGSR as internal fixation methods can be determined radio graphically.","PeriodicalId":104363,"journal":{"name":"Open Access Journal of Veterinary Science & Research","volume":"501 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127040361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Activation of Heterophils and Monocytes in Chicken with a Formulation Containing a Seaweed Extract from Ulva armoricana","authors":"F. Bussy","doi":"10.23880/oajvsr-16000208","DOIUrl":"https://doi.org/10.23880/oajvsr-16000208","url":null,"abstract":"Responsiveness to invasive pathogens, clearance via the inflammatory response, and activation of appropriate acquired responses are all coordinated by innate host defenses. We have previously demonstrated that a purified ulvan extract of Ulva armoricana is able to activate avian heterophils and monocytes in vitro and in vivo , leading to in vivo release of cytokines including interleukin 1 β (IL1β), interferon α (IFNα) and interferon γ (IFNγ), in a transient and dose-dependent manner. In this study, we used the same protocol to evaluate a formulated version of this extract, called Searup ® . Our experiments showed that a single oral administration of this product at the dose recommended for use in the farm, results in heterophils and monocytes activation. In heterophils, activation was evidenced by β-D-glucuronidase release and increased mRNA expression of IL1β, IFNα and IFNγ. In monocytes, the expression of IFNγ and inducible nitrite oxide synthase (iNOS) were also up-regulated. Finally, plasmatic NO increased significantly on day 1, decreased on day 2 and was no longer significant at day 3. A similar pattern was observed for β-D-glucuronidase and for the modifications of the transcription profiles in monocytes as well as in heterophils. The only notable exception is gene transcription of 2'-5' Oligoadenylate Synthase, which is maximal at day 2 in monocytes. Due to its protective role in virus infection, this may constitute an additional layer of protection for this class of pathogens. Together our results show that the formulated solution, Searup ® , similarly to the purified extract allow to activate monocytes and heterophils but with some variations in the cytokines profiles and may provide protection against a larger variety of pathogens.","PeriodicalId":104363,"journal":{"name":"Open Access Journal of Veterinary Science & Research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133382160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantitative Detection of Aflatoxin M1, Ochratoxin and Zearalenone in Fresh Raw Milk o f Cow, Buffalo, Sheep and Goat by UPLC XEVO - TQ i n Dakahlia Governorate, Egypt","authors":"Mahmoud M. Elalfy","doi":"10.23880/oajvsr-16000181","DOIUrl":"https://doi.org/10.23880/oajvsr-16000181","url":null,"abstract":"Animals’ derived food as milk is highly nutritive food for human and substitute mother’s milk for children especially after 6 months. To better produce and maintain sa fe milk and milk product, Ultra Performance Liquid Chromatography XEVO - TQ (UPLC) used to monitor mycotoxins as aflatoxin, ochratoxin and zearalenone levels in fresh raw milk of dairy domestic animals. AFL - M1 was detected in all samples in cow, buffalo, she ep and goat milk with different concentration ranged from high, medium and very low with mean 906, 811.1, 1394.86 and 1183.68 ng/L respectively. According worldwide standard for aflatoxin M1 level in milk as EC and according US FDA Limit, all samples of raw milk exceed this limit up to 100ng /l while 50%, 80, 90 and 60% exceed US FDA Limit. Notably, the Egyptian raw milk is free from ochratoxin and zearalenone mycotoxin. Taken collectively , strict strategies should be taken to reduce level of aflatoxin in raw milk between producer and consumer and so reduce risk of adverse effect on health.","PeriodicalId":104363,"journal":{"name":"Open Access Journal of Veterinary Science & Research","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115573979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Canine Leishmaniosis: A Silent Burden in Southeast Asia and Elucidating Existing Knowledge Gap","authors":"A. Pa","doi":"10.23880/oajvsr-16000172","DOIUrl":"https://doi.org/10.23880/oajvsr-16000172","url":null,"abstract":"Canine leishmaniosis is one of the most important canine vector - borne diseases (CVBD) caused by protozoan Leishmania sp . which pose zoonotic threat as some of its species are zoonotic. This parasitic disease is classified as Neglected Tropical Disease (NTD) and can be found in parts of the tropics, subtropics and southern Europe. A lot of studies had been carried out across the globe but lack in Southeast Asia, thus its epi zootiology is still poorly understood. This article is meant to create awareness of the existence of this zoonotic disease amongst veterinary personnel, scientific community and readers.","PeriodicalId":104363,"journal":{"name":"Open Access Journal of Veterinary Science & Research","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127057101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of the Tibial Anatomical-Mechanical Axis Angle and Patellar Positions between Labrador Retrievers and Golden Retrievers with and without Cranial Cruciate Ligament Rupture","authors":"G. L.","doi":"10.23880/oajvsr-16000199","DOIUrl":"https://doi.org/10.23880/oajvsr-16000199","url":null,"abstract":"This study investigated proximodistal and craniocaudal patellar positions and assessed these positions with the tibial anatomical-mechanical axis angle (AMA-angle), tibial plateau angle (TPA), relative tibial tuberosity width (rTTW), and Z-angle in Labrador Retrievers (LR) and Golden Retrievers (GR) with and without cranial cruciate ligament rupture (CCLR). Mediolateral radiographs were obtained from 2 groups. The affected group had a normal contralateral stifle measured at the time of unilateral surgically confirmed CCLR, which developed a subsequent contralateral CCLR (SC-CCLR; 40 dogs), and the control group (60 dogs aged >11 years) had normal stifles. In the SC-CCLR group, 95% of the tibial anatomical axes (AAs) were cranial (CR) to the patella, with a median (range) AMA-angle of 2.92° (1.65°-4.92°), while in the control group, 93% of the stifles had AAs caudal (CA) to or in the middle (M) of the patella, with a median (range) AMA-angle of 1.03° (0°-3.52°). The craniocaudal position of the patella was correlated statistically with the AMA-angles (median (range), 0.86° (0-1.61°), 1.87° (1.22-2.7°), and 2.97° (1.72-4.92°) in the CA, M, and CR positions, respectively, but not with other tibial measurements (p<0.0001). The patellar height did not differ between the groups (p<0.0001). The highly significant difference found in the AMA-angle and the craniocaudal patellar position between LR and GR with or without CCL injury suggest that craniocaudal angulation of the proximal tibia could influence the development of canine CCLR.","PeriodicalId":104363,"journal":{"name":"Open Access Journal of Veterinary Science & Research","volume":"145 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134034263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feline Alveolar Osteitis: Osseodensification with Implant Placement Protocol","authors":"G. Kurtzman","doi":"10.23880/oajvsr-16000212","DOIUrl":"https://doi.org/10.23880/oajvsr-16000212","url":null,"abstract":"Feline dental implants are becoming a predictable and viable treatment option for the replacement of lost canines due to maxillary alveolar osteitis (AO) a painful condition, commonly experienced by felines. Surgical extraction and debridement remains the treatment of choice for this complex inflammatory process. Future complications however can be a common sequela of maxillary canine loss. The case presented demonstrates successful surgical extraction of a maxillary canine with implant placement following the osseodensification protocol and utilizing the sockets osteitis buttressing bone formation to promote a positive result with final restoration of the implant with a crown 13 weeks post implant placement.","PeriodicalId":104363,"journal":{"name":"Open Access Journal of Veterinary Science & Research","volume":"795 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129078546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Joint use of Ca – Modified Double-Strained RNA as an Immunostimulator with a Vaccine for the Prevention of Food andMouth Disease (FMD)","authors":"Markosyan Th","doi":"10.23880/OAJVSR-16000201","DOIUrl":"https://doi.org/10.23880/OAJVSR-16000201","url":null,"abstract":"The purpose of this work is to study the effect of combined use of the immunostimulant preparation which is double-stranded Ca-modified RNA with inactivated FMD vaccine for cattle against A, O and Asia-1 subtypes of FMD. Preparation have been received from sodium nucleinate or allocated from a killer yeast of Saccharomices cerewisiae. The modification of Ca ions assayed by the addition of sterile solution of calcium chloride. Based on received data it can be concluded that the using of immunomodulator in cattle induces more early and high immune response. The FMD vaccine intramuscular administration together with the preparation provides high enough of an immune response and high titer of antibody maintained for a period of 90 days (time of observation).","PeriodicalId":104363,"journal":{"name":"Open Access Journal of Veterinary Science & Research","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126492893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using Food Grate Stainless Steel Rods for Internal Fixation of Transverse Fractures in Rabbits","authors":"Humam H. Nazht","doi":"10.23880/oajvsr-16000188","DOIUrl":"https://doi.org/10.23880/oajvsr-16000188","url":null,"abstract":"This project was designed to replace the medical stainless steel pins (MSP) which used in internal fixation of the transverse fractures femoral bone in rabbits by the food grate stainless steel rods (FGSR) 2.25 and 2.5 mm which used in the food industry. 175 adult local bree d rabbits were used from 2008 – 2019, 60 of them used to induced transverse fractures in the mid shift of femoral bones, the o thers employed to remove 1cm of diaphysis bone and replaced by either xeno - bony sheep implantation in 26 rabbits, or replaced by xeno - bony bov ine implantation in 75 rabbits , while the others14 rabbits replaced by the synthetics bony nano scaffold implantation, then all fixed by FGSR as internal fixation devices for the induced femoral fractures or fixation the implanted devices. The parameters w hich were used for evaluation were, the p hysical and general examination , laborato ry analysis for elements ratio, clinical application with radiographic and histopathological examination . The results revealed FGSR easy to find and use and handling , with lo w prize and high economic values, and the chemical elemen ts ratio the same as in the MSP , nobody rejection or complication , not changed before and within and after implantation and sterilization , give stability, and support the body weight , and the rabbits quickly used affected limb in walking and running, the FGSR visible radio graphically with good alignment of fractures bones with normal healing radiographic finding, while the histopathological examination shows normal histopathological changes during fr actures healing processing . The conclusion FGSR size 2.25 – 2.5 mm can be used strongly and successfully in internal fixation of induced transverse mid shift fractures of femoral bones in rabbits instead of the MSP.","PeriodicalId":104363,"journal":{"name":"Open Access Journal of Veterinary Science & Research","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131239765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}