Colloids and Interfaces最新文献_第6页

Amplification of SERS Signal of Methotrexate Using Beta-Cyclodextrin Modified Silver Nanoparticles β -环糊精修饰纳米银对甲氨蝶呤SERS信号的放大研究

IF 2.4

Colloids and Interfaces Pub Date : 2023-05-26 DOI: 10.3390/colloids7020042

N. E. Markina, I. Goryacheva, A. Markin

{"title":"Amplification of SERS Signal of Methotrexate Using Beta-Cyclodextrin Modified Silver Nanoparticles","authors":"N. E. Markina, I. Goryacheva, A. Markin","doi":"10.3390/colloids7020042","DOIUrl":"https://doi.org/10.3390/colloids7020042","url":null,"abstract":"The paper describes the use of native β-cyclodextrin (CD) for the modification of silver nanoparticles (AgNPs) in order to improve the determination of the anticancer drug methotrexate (MTX) using surface-enhanced Raman spectroscopy (SERS). A control experiment with unmodified AgNPs showed that the strong SERS signal of MTX can only be achieved in alkaline media. However, competitive interactions and the strong background signal of human body fluid components significantly challenge MTX determination in real samples. While previous reports propose the use of thorough sample pretreatment (e.g., solid phase extraction), the application of CD-modified AgNPs increases the SERS signal of MTX in neutral media by seven times which enables simplifying the analysis and improving its accuracy by reducing the influence of endogenous components of body fluids. A detailed study of the synthesis conditions (CD concentration and reaction time) and SERS registration conditions (pH, NaCl concentration, dilution of urine samples) was performed to maximize the analytical signal and signal-to-noise ratio. The final assay was tested for MTX determination in artificially spiked samples of real human urine. The results demonstrated that MTX can be determined within the concentration range suitable for therapeutic drug monitoring (20–300 μg mL−1) with satisfactory precision (6–15% RSD), accuracy (95–111% apparent recovery), and limit of detection (0.3 μg mL−1).","PeriodicalId":10433,"journal":{"name":"Colloids and Interfaces","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46869282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experimental and Machine Learning Studies on Chitosan-Polyacrylamide Copolymers for Selective Separation of Metal Sulfides in the Froth Flotation Process 壳聚糖-聚丙烯酰胺共聚物在泡沫浮选过程中选择性分离金属硫化物的实验和机器学习研究

IF 2.4

Colloids and Interfaces Pub Date : 2023-05-17 DOI: 10.3390/colloids7020041

K. Monyake, Taihao Han, D. Ali, L. Alagha, Aditya Kumar

{"title":"Experimental and Machine Learning Studies on Chitosan-Polyacrylamide Copolymers for Selective Separation of Metal Sulfides in the Froth Flotation Process","authors":"K. Monyake, Taihao Han, D. Ali, L. Alagha, Aditya Kumar","doi":"10.3390/colloids7020041","DOIUrl":"https://doi.org/10.3390/colloids7020041","url":null,"abstract":"The froth flotation process is extensively used for the selective separation of valuable base metal sulfides from uneconomic associated minerals. However, in this complex multiphase process, various parameters need to be optimized to ensure separation selectivity and peak performance. In this study, two machine learning (ML) models, artificial neural network (ANN) and random forests (RF), were used to predict the efficiency of in-house synthesized chitosan-polyacrylamide copolymers (C-PAMs) in the depression of iron sulfide minerals (i.e., pyrite) while valuable base metal sulfides (i.e., galena and chalcopyrite) were floated using nine flotation variables as inputs to the models. The prediction performance of the models was rigorously evaluated based on the coefficient of determination (R2) and the root-mean-square error (RMSE). The results showed that the RF model was able to produce high-fidelity predictions of the depression of pyrite once thoroughly trained as compared to ANN. With the RF model, the overall R2 and RMSE values were 0.88 and 4.38 for the training phase, respectively, and R2 of 0.90 and RMSE of 3.78 for the testing phase. As for the ANN, during the training phase, the overall R2 and RMSE were 0.76 and 4.75, respectively, and during the testing phase, the R2 and RMSE were 0.65 and 5.42, respectively. Additionally, fundamental investigations on the surface chemistry of C-PAMs at the mineral–water interface were conducted to give fundamental insights into the behavior of different metal sulfides during the flotation process. C-PAM was found to strongly adsorb on pyrite as compared to galena and chalcopyrite through zeta potential, X-ray photoelectron spectroscopy (XPS), and adsorption density measurements. XPS tests suggested that the adsorption mechanism of C-PAM on pyrite was through chemisorption of the amine and amide groups of the polymer.","PeriodicalId":10433,"journal":{"name":"Colloids and Interfaces","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43903120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morphological Diversity in Diblock Copolymer Solutions: A Molecular Dynamics Study 二嵌段共聚物溶液的形态多样性:分子动力学研究

IF 2.4

Colloids and Interfaces Pub Date : 2023-05-09 DOI: 10.3390/colloids7020040

Senyuan Liu, R. Sureshkumar

{"title":"Morphological Diversity in Diblock Copolymer Solutions: A Molecular Dynamics Study","authors":"Senyuan Liu, R. Sureshkumar","doi":"10.3390/colloids7020040","DOIUrl":"https://doi.org/10.3390/colloids7020040","url":null,"abstract":"Coarse-grained molecular dynamics simulations that incorporate explicit water-mediated hydrophilic/hydrophobic interactions are employed to track spatiotemporal evolution of diblock copolymer aggregation in initially homogeneous solutions. A phase portrait of the observed morphologies and their quantitative geometric features such as aggregation numbers, packing parameters, and radial distribution functions of solvent/monomers are presented. Energetic and entropic measures relevant to self-assembly such as specific solvent accessible surface area (SASA) and probability distribution functions (pdfs) of segmental stretch of copolymer chains are analyzed. The simulations qualitatively capture experimentally observed morphological diversity in diblock copolymer solutions. Topologically simpler structures predicted include spherical micelles, vesicles (polymersomes), lamellae (bilayers), linear wormlike micelles, and tori. More complex morphologies observed for larger chain lengths and nearly symmetric copolymer compositions include branched wormlike micelles with Y-shaped junctions and cylindrical micelle networks. For larger concentrations, vesicle strands, held together by hydrogen bonds, and “giant” composite aggregates that consist of lamellar, mixed hydrophobic/hydrophilic regions and percolating water cores are predicted. All structures are dynamic and exhibit diffuse domain boundaries. Morphology transitions across topologically simpler structures can be rationalized based on specific SASA measurements. PDFs of segmental stretch within vesicular assemblies appear to follow a log-normal distribution conducive for maximizing configuration entropy.","PeriodicalId":10433,"journal":{"name":"Colloids and Interfaces","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47135847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effects of Viscosity and Capillarity on Nonequilibrium Distribution of Gas Bubbles in Swelling Liquid–Gas Solution 粘度和毛细作用对膨胀液-气溶液中气泡不平衡分布的影响

IF 2.4

Colloids and Interfaces Pub Date : 2023-05-05 DOI: 10.3390/colloids7020039

A. Shchekin, A. Kuchma, E. Aksenova

引用次数: 0

Superspreading Surfactant on Hydrophobic Porous Substrates 疏水性多孔基质上的超扩散表面活性剂

IF 2.4

Colloids and Interfaces Pub Date : 2023-05-04 DOI: 10.3390/colloids7020038

Wellington Tafireyi, Max Littlewood, H. C. H. Bandulasena, A. Trybala, V. Starov

引用次数: 0

Rheology of Pickering Emulsions Stabilized and Thickened by Cellulose Nanocrystals over Broad Ranges of Oil and Nanocrystal Concentrations 纤维素纳米晶体在大范围油和纳米晶体浓度下稳定和增稠皮克林乳状液的流变学

IF 2.4

Colloids and Interfaces Pub Date : 2023-04-24 DOI: 10.3390/colloids7020036

Saumay Kinra, R. Pal

引用次数: 6

Effect of Surfactants/Gels on the Stability of Boron Particle Dispersion in Liquid Fuel 表面活性剂/凝胶对硼颗粒在液体燃料中分散稳定性的影响

IF 2.4

Colloids and Interfaces Pub Date : 2023-04-24 DOI: 10.3390/colloids7020037

J. Bullón, Ronald Marquez, Franklin Zambrano, P. Dilipkumar, S. Sonawane, S. Srinath

{"title":"Effect of Surfactants/Gels on the Stability of Boron Particle Dispersion in Liquid Fuel","authors":"J. Bullón, Ronald Marquez, Franklin Zambrano, P. Dilipkumar, S. Sonawane, S. Srinath","doi":"10.3390/colloids7020037","DOIUrl":"https://doi.org/10.3390/colloids7020037","url":null,"abstract":"Metal-based nanofillers are used as disperssants to enhance thermal conductivity for a minimal fuel requirement to extract maximum energy. To achieve this, metal-based nanofillers must be suspended uniformly into jet fuel so that desired propulsive characteristics can be achieved. However, the dispersion of the metal-based nanofillers into the jet fuel is a critical challenge due to the density and viscosity that are independent parameters with a scattered relation. Hence, in the current work, we intended to investigate the propulsive characteristics of the JP-10 (Exo-Tetra Hydro Dicyclopentadiene) jet fuel dispersed with boron particles (BP) at various concentrations. The challenge involved in the current work was to make dispersion stable for a longer period due to the absence of functional groups entailed to BPs. Alongside JP-10, is a single-component, high-density hydrocarbon that can that can exhibit thixotropic characteristic in nature and hence combining with BP makes it difficult; hence, there is a need for oligomerization or the addition of surfactants that are derived from oligomers. Hence, in the current work, the BPs were dispersed in jet fuel by the ultrasound probe with various surfactants, namely Hydroxyl Terminated Polybutadiene (HTPB), Triton X-100, Span 80, Oleic acid, and Sodium dodecyl sulfate (SDS), followed by an investigation of their stability. The experimental studies reported that the stability of the boron was longest, for 54 h, with 0.5 wt.% boron and 0.3 wt.% HTPB at a micron size of the boron particles (325 ± 25 nm). The uniform dispersion of the particles was achieved by the effect of the ultrasound probe. From the thermal analysis, a total weight loss of 25% was observed within a short range of temperatures, i.e., 50 to 200 °C.","PeriodicalId":10433,"journal":{"name":"Colloids and Interfaces","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46117606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing Structural Stability of Oil-Shell Microbubbles via Incorporation of a Gold Nanoparticle Protective Shell for Theranostic Applications 通过加入金纳米颗粒保护壳来增强油壳微泡的结构稳定性

IF 2.4

Colloids and Interfaces Pub Date : 2023-04-23 DOI: 10.3390/colloids7020034

Marzieh Ataei, Hsiu‐Ping Yi, Aida Zahra Taravatfard, Ken Y Lin, Abraham P. Lee

{"title":"Enhancing Structural Stability of Oil-Shell Microbubbles via Incorporation of a Gold Nanoparticle Protective Shell for Theranostic Applications","authors":"Marzieh Ataei, Hsiu‐Ping Yi, Aida Zahra Taravatfard, Ken Y Lin, Abraham P. Lee","doi":"10.3390/colloids7020034","DOIUrl":"https://doi.org/10.3390/colloids7020034","url":null,"abstract":"Phospholipid-stabilized microbubbles are utilized as contrast agents in medical ultrasound imaging, and researchers are currently investigating their potential as theranostic agents. Due to the inadequate water solubility and poor stability of numerous new therapeutics, the development of stable microbubbles with the capacity to encapsulate hydrophobic therapeutics is necessary. Herein, we proposed a flow-focusing microfluidic device to generate highly monodispersed, phospholipid-stabilized dual-layer microbubbles for theranostic applications. The stability and microstructural evolution of these microbubbles were investigated by microscopy and machine-learning-assisted segmentation techniques at different phospholipid and gold nanoparticle concentrations. The double-emulsion microbubbles, formed with the combination of phospholipids and gold nanoparticles, developed a protective gold nanoparticle shell that not only acted as a steric barrier against gas diffusion and microbubble coalescence but also alleviated the progressive dewetting instability and the subsequent cascade of coalescence events.","PeriodicalId":10433,"journal":{"name":"Colloids and Interfaces","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43900613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Matrices of Native and Oxidized Pectin and Ferrous Bisglycinate and Their In Vitro Behavior through Gastrointestinal Conditions 天然和氧化果胶和二甘氨酸亚铁基质及其在胃肠道条件下的体外行为

IF 2.4

Colloids and Interfaces Pub Date : 2023-04-23 DOI: 10.3390/colloids7020035

M. Jiménez, Daniela Viteri, Daniela Oña, M. León, V. Ochoa-Herrera, Natalia Carpintero, F. Sepulcre, J. Álvarez-Barreto

{"title":"Matrices of Native and Oxidized Pectin and Ferrous Bisglycinate and Their In Vitro Behavior through Gastrointestinal Conditions","authors":"M. Jiménez, Daniela Viteri, Daniela Oña, M. León, V. Ochoa-Herrera, Natalia Carpintero, F. Sepulcre, J. Álvarez-Barreto","doi":"10.3390/colloids7020035","DOIUrl":"https://doi.org/10.3390/colloids7020035","url":null,"abstract":"Colloidal matrices of native and oxidized pectin were developed to improve iron bioavailability through the digestive tract. Ferrous bisglycinate (Gly-Fe), obtained by precipitation of glycine chelation to Fe2+, was mixed with native and peroxide-oxidized citrus pectin, and subsequently lyophilized. Controls included matrices with iron and glycine without chelation. The resulting samples were characterized through FTIR, SEM, and TGA/DSC before and after in vitro digestion, which was performed in simulated salivary, gastric, and intestinal fluids. During these digestions, swelling capacity and iron release were assessed. All matrix formulations were porous, and while pectin oxidation did not alter architecture, it changed their properties, increasing thermal stability, likely due to greater number of interaction possibilities through carbonyl groups generated during oxidation. This also resulted in lower swelling capacity, with greater stability observed when using the chelated complex. Higher swelling was found in gastric and intestinal fluids. Pectin oxidation also increased retention of the chelated form, contrary to what was observed with unchelated iron. Thus, there is an important effect of pectin oxidation combined with iron in the form of ferrous biglyscinate on matrix stability and iron release through the digestive tract. These matrices could potentially improve iron bioavailability, diminishing organoleptic changes in fortified iron foods.","PeriodicalId":10433,"journal":{"name":"Colloids and Interfaces","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45329579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How Dimensionality Affects the Structural Anomaly in a Core-Softened Colloid 维度如何影响核心软化胶体的结构异常

IF 2.4

Colloids and Interfaces Pub Date : 2023-04-21 DOI: 10.3390/colloids7020033

L. Krott, J. R. Bordin

{"title":"How Dimensionality Affects the Structural Anomaly in a Core-Softened Colloid","authors":"L. Krott, J. R. Bordin","doi":"10.3390/colloids7020033","DOIUrl":"https://doi.org/10.3390/colloids7020033","url":null,"abstract":"The interaction between hard core–soft shell colloids are characterized by having two characteristic distances: one associated with the penetrable, soft corona and another one corresponding to the impenetrable core. Isotropic core-softened potentials with two characteristic length scales have long been applied to understand the properties of such colloids. Those potentials usually show water-like anomalies, and recent findings have indicated the existence of multiple anomalous regions in the 2D limit under compression, while in 3D, only one anomalous region is observed. In this direction, we perform molecular dynamics simulations to unveil the details about the structural behavior in the quasi-2D limit of a core-softened colloid. The fluid was confined between highly repulsive solvophobic walls, and the behavior at distinct wall separations and colloid densities was analyzed. Our results indicated a straight relation between the 2D- or 3D-like behavior and layer separation. We can relate that if the system behaves as independent 2D-layers, it will have a 2D-like behavior. However, for some separations, the layers are connected, with colloids hopping from one layer to another, thus having a 3D-like structural behavior. These findings fill the gap in the depiction of the anomalous behavior from 2D to 3D.","PeriodicalId":10433,"journal":{"name":"Colloids and Interfaces","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49294074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0