{"title":"Neuropsychiatric Symptoms and Alzheimer's Disease Severity. A Focus on Sex-Differences.","authors":"Antonina Luca, Maria Luca, Alessandro Serretti","doi":"10.1080/07317115.2025.2518093","DOIUrl":"https://doi.org/10.1080/07317115.2025.2518093","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the present study was to investigate possible sex predictors in the severity of NPS in a large cohort of patients with AD and to assess the role of severity in sex-related differences in NPS.</p><p><strong>Methods: </strong>Four hundred and twenty-four participants (295 women, mean age 78.4 ± 8.3 years, mean disease duration 7.4 ± 8.5 years) were included with a diagnosis of AD according to NINCDS/ADRDA criteria. Clinical data and presence of NPS were collected from family interview, medical records, and patient interview and examination. Dementia severity was assessed using the Clinical Dementia Rating Scale (CDRS) extended version.</p><p><strong>Results: </strong>CDRS score was available for 407 participants (mean score 2.6 ± 1.1); 407 (22.1%) patients had CRDS = 1, 104 (25.5%) had CRDS = 2, 127 (31.2%) had CRDS = 3, 64 (15.7%) had CDRS = 4 and 22 (15.4%) had CDRS = 5. Apathy (85.7%), agitation or restlessness (75.1%) and paranoia (59.4%) were the most common NPS. Higher CDRS scores were associated with several neuropsychiatric features, including apathy, wandering and physical aggression. In the sex-stratified analysis, NPS were associated with more severe AD only in men.</p><p><strong>Conclusions: </strong>Our findings suggest relevant sex differences in NPS with increasing severity.</p><p><strong>Clinical implications: </strong>A timely and targeted behavioral management could improve treatment outcome.</p>","PeriodicalId":10376,"journal":{"name":"Clinical Gerontologist","volume":" ","pages":"1-7"},"PeriodicalIF":2.6,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gema Soria-Urios, Jesus Gonzalez-Moreno, Encarnacion Satorres, Juan C Meléndez
{"title":"Effects of Simple Reminiscence on Reminiscence Functions in Older Adults with Mild Cognitive Impairment Due to Alzheimer's Disease.","authors":"Gema Soria-Urios, Jesus Gonzalez-Moreno, Encarnacion Satorres, Juan C Meléndez","doi":"10.1080/07317115.2025.2518100","DOIUrl":"https://doi.org/10.1080/07317115.2025.2518100","url":null,"abstract":"<p><strong>Objectives: </strong>Simple reminiscence has been used as a non-pharmacological strategy to improve emotional well-being and adaptation in older adults, particularly those with mild cognitive impairment due to Alzheimer's disease. This study examined the effects of a simple reminiscence-based intervention on different reminiscence functions in this population.</p><p><strong>Methods: </strong>113 participants were randomly assigned to an experimental (<i>n</i> = 61) or control group (<i>n</i> = 52). The experimental group received 16 reminiscence sessions over eight weeks. Assessments occurred pre-, post-intervention, and at follow-up. The eight subscales of the Reminiscence Functions Scale served as the study's primary outcome variables. Intervention effects were analyzed using 2 × 3 mixed ANOVAs (group × time).</p><p><strong>Results: </strong>The results showed significant improvements in adaptive reminiscence functions, including identity, problem-solving, and preparation for death, as well as in the prosocial functions of conversation and teaching/informing in the experimental group compared to the control group.</p><p><strong>Conclusions: </strong>These findings suggest that simple reminiscence can be an effective strategy for preserving and enhancing adaptive reminiscence functions in older adults with mild cognitive impairment due to Alzheimer's disease. Clinical Implications: This intervention can be integrated into routine care for individuals with cognitive impairment, helping maintain emotional-cognitive functioning and improve quality of life.</p>","PeriodicalId":10376,"journal":{"name":"Clinical Gerontologist","volume":" ","pages":"1-12"},"PeriodicalIF":2.6,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Demetra Christodoulou, Suzanne Reeves, Naashoma P Carvalho, Judith Stellman, Rebecca L Gould
{"title":"A Systematic Review of Third-Wave Therapies to Reduce Distress and Improve Wellbeing and Quality of Life in People with Parkinson's Disease.","authors":"Demetra Christodoulou, Suzanne Reeves, Naashoma P Carvalho, Judith Stellman, Rebecca L Gould","doi":"10.1080/07317115.2025.2511957","DOIUrl":"https://doi.org/10.1080/07317115.2025.2511957","url":null,"abstract":"<p><strong>Objectives: </strong>This systematic review assessed use of third-wave psychotherapies in reducing psychological distress and improving psychological well-being and quality of life in people with Parkinson's disease and critically evaluated intervention adaptations.</p><p><strong>Methods: </strong>A literature search, conducted across five databases identified randomized controlled trials (RCTs) evaluating third-wave psychotherapies for individuals with Parkinson's disease.</p><p><strong>Results: </strong>Ten RCTs were identified of which nine evaluated mindfulness-based interventions, and one acceptance and commitment therapy. Methodological quality ranged from moderate to high, but sample sizes were small, and only one study was adequately powered. Five reported on Parkinson's specific adaptations. The trial with the largest sample size reported a significant effect of Mindfulness Yoga on depression and anxiety, psychological well-being and quality of life. Other findings were mixed across all outcomes.</p><p><strong>Conclusions: </strong>There was evidence of an effect of Mindfulness Yoga on our pre-defined outcomes. Pilot and feasibility trials showed that mindfulness-based interventions were well received and provided feedback on adaptations. There was a lack of data to draw conclusions regarding non-mindfulness-based therapies.</p><p><strong>Clinical implications: </strong>Larger trials of mindfulness-based interventions are required to establish the clinical meaningfulness of treatment effects. Further research is needed to adapt and explore on non-mindfulness-based interventions such as acceptance and commitment therapy.</p>","PeriodicalId":10376,"journal":{"name":"Clinical Gerontologist","volume":" ","pages":"1-24"},"PeriodicalIF":2.6,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Relationship Between Self-Reported Hearing Loss and Depression Among Older Adults: The Moderating Effect of Digital Device Use.","authors":"Jayeong Kim, Yeji Hwang","doi":"10.1080/07317115.2025.2510285","DOIUrl":"https://doi.org/10.1080/07317115.2025.2510285","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the relationship between hearing loss and depression of older adults and examine how digital device use moderates the relationship between hearing loss and depression.</p><p><strong>Methods: </strong>Secondary data analyses were conducted using data from the 2020 National Survey of Older Koreans (<i>N</i> = 9,920). Weighted linear regression analyses were conducted to examine the relationship between hearing loss and depression and moderating effect of digital device use.</p><p><strong>Results: </strong>Approximately 23.2% of the participants reported hearing loss. Hearing loss was significantly associated with increased depression (β = 0.074, <i>p</i> = .005). Digital device use had a marginally significant moderating effect on the relationship between hearing loss and depression (β = 0.050, <i>p</i> = .054).</p><p><strong>Conclusions: </strong>Hearing loss is associated with greater depression among older adults. Our findings suggest that digital device use does not alleviate depression in older adults with hearing loss. Future studies should consider the specific aspects of digital device use and post-COVID-19 changes to better understand the impact of digital device use on hearing loss and depression.</p><p><strong>Clinical implications: </strong>Since hearing loss is significantly associated with higher levels of depression in older adults, mental health should be assessed if healthcare professionals work with older adults with hearing loss.</p>","PeriodicalId":10376,"journal":{"name":"Clinical Gerontologist","volume":" ","pages":"1-15"},"PeriodicalIF":2.6,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient Values Influence Clinician Judgment of Medical Decision-Making Capacity.","authors":"Emilee M Ertle, Darby M Simon, Benjamin T Mast","doi":"10.1080/07317115.2025.2505581","DOIUrl":"https://doi.org/10.1080/07317115.2025.2505581","url":null,"abstract":"<p><strong>Objectives: </strong>Medical decision-making capacity assessments commonly focus on patient communication, understanding, appreciation, and reasoning, with less emphasis on patient values or preferences that could influence their medical decision. The current study investigates the role of patient values in capacity assessments.</p><p><strong>Methods: </strong>One hundred and ten clinicians with experience conducting medical decision-making capacity assessments completed an online survey. Participants read two vignettes about a patient with questionable capacity and were asked to determine whether the patient had capacity. For the second vignette, participants were randomly assigned to read a vignette which contained information about the patient's longstanding values or a vignette without this information.</p><p><strong>Results: </strong>When information about the patient's values and preferences was included in the vignette, participants were significantly more likely to determine the patient had capacity to make a medical decision. Other significant contributors to a clinician's judgment included experience conducting medical decision-making capacity assessments in a VA hospital and whether the clinician prioritized the patient's autonomy or their health and safety.</p><p><strong>Conclusions: </strong>A patient's values and preferences provide important context which significantly influences clinician judgment of capacity.</p><p><strong>Clinical implications: </strong>Clinicians should regularly assess a patient's values and preferences when conducting capacity assessments, as this may promote patient autonomy.</p>","PeriodicalId":10376,"journal":{"name":"Clinical Gerontologist","volume":" ","pages":"1-12"},"PeriodicalIF":2.6,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julian A Scheffer, Darius T Levan, Jenna L Wells, Dolores Gallagher-Thompson, Kevin J Grimm, Kuan-Hua Chen, Casey K Brown, Breanna M Bullard, Claire I Yee, Scott L Newton, Enna Y Chen, Jennifer J Merrilees, David Moss, Gene Wang, Robert W Levenson
{"title":"In-Home Assistive Technology May Help Protect Dementia Caregivers from Declining Sleep Efficiency: A Randomized Control Trial.","authors":"Julian A Scheffer, Darius T Levan, Jenna L Wells, Dolores Gallagher-Thompson, Kevin J Grimm, Kuan-Hua Chen, Casey K Brown, Breanna M Bullard, Claire I Yee, Scott L Newton, Enna Y Chen, Jennifer J Merrilees, David Moss, Gene Wang, Robert W Levenson","doi":"10.1080/07317115.2025.2499812","DOIUrl":"https://doi.org/10.1080/07317115.2025.2499812","url":null,"abstract":"<p><strong>Objectives: </strong>Caregivers for people with dementia (PWDs) often experience sleep problems due to stressors associated with their role (e.g. concern about PWDs' nighttime wandering). We investigated whether a technology system, People Power Caregiver (PPCg), that helps monitor the caregiver's home would benefit caregivers' sleep.</p><p><strong>Methods: </strong>Primary caregivers of PWDs (Study 1: <i>N</i> = 70, Age <i>M</i> = 64.54, SD = 11.82, range = 35-84; Study 2: <i>N</i> = 92, Age <i>M</i> = 62.73, SD = 11.10, range = 32-89) were assigned to a fully activated PPCg condition or control condition (Study 1: partially active PPCg; Study 2: waitlist control). Caregivers completed the Pittsburgh Sleep Quality Index at baseline, three-months, and six-months.</p><p><strong>Results: </strong>Caregivers in the control conditions reported significantly worsening sleep efficiency whereas in comparison, those in the active conditions reported improving sleep efficiency.</p><p><strong>Conclusions: </strong>Given how critical sleep is both for caregivers' health and the care they provide, these findings underscore potential benefits of in-home technologies for protecting caregivers' sleep.</p><p><strong>Clinical implications: </strong>Technology-based interventions that help monitor the home may support caregivers' sleep. Protecting caregivers' sleep may also preserve their ability to provide high-quality care as their loved one's disease and associated functional decline progresses.</p>","PeriodicalId":10376,"journal":{"name":"Clinical Gerontologist","volume":" ","pages":"1-14"},"PeriodicalIF":2.6,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erol Ekiz, Arjan C Videler, Machteld A Ouwens, Sebastiaan P J van Alphen
{"title":"STEPPS for Over-Controlled and Under-Controlled Emotional Dysregulation in Older Adults with Personality Disorders: A Case Study.","authors":"Erol Ekiz, Arjan C Videler, Machteld A Ouwens, Sebastiaan P J van Alphen","doi":"10.1080/07317115.2025.2506769","DOIUrl":"https://doi.org/10.1080/07317115.2025.2506769","url":null,"abstract":"<p><strong>Objectives: </strong>This paper aims to present a clinical illustration of under-controlled and over-controlled emotional dysregulation behaviors in older adults with personality disorders (PD). Furthermore, another aim is to explore how Systems Training for Emotional Predictability and Problem Solving for Older Adults (STEPPS-OA) can be useful for both types of emotional dysregulation.</p><p><strong>Methods: </strong>A 65-year-old woman with emotional under-control and a 67-year-old woman with emotional over-control participated in STEPPS-OA. STEPPS-OA is a treatment program consisting of 21 weekly group sessions, individual sessions and support group meetings.</p><p><strong>Results: </strong>The participant with under-control struggled with impulsivity and destructive behaviors. She learned to use techniques to recognize the buildup of tension and manage emotions. The participant with over-control struggled with difficulties in differentiating and expressing emotions. She learned to use techniques to recognize suppressed feelings and began practicing assertive behaviors.</p><p><strong>Conclusions: </strong>Emotional dysregulation can occur from either over-controlled or under-controlled behaviors in older adults with PD. STEPPS-OA seems to be a promising treatment option for both types of behavior because the interventions seem to fit both cases.</p><p><strong>Clinical implications: </strong>STEPPS-OA is a promising treatment option for older adults with PD and emotional over-controlled and under-controlled behaviors.</p>","PeriodicalId":10376,"journal":{"name":"Clinical Gerontologist","volume":" ","pages":"1-8"},"PeriodicalIF":2.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
George Lin, Tracy Kuo Lin, Mohammed Alluhidan, Rana Saber, Mariam M Hamza, Severin Rakic, Abdulrahman Alfaisal, Adwaa Alamri, Volkan Cetinkaya, Nahar Alazmi
{"title":"Evidence for Building an Integrated Dementia Healthcare System: A Systematic Review.","authors":"George Lin, Tracy Kuo Lin, Mohammed Alluhidan, Rana Saber, Mariam M Hamza, Severin Rakic, Abdulrahman Alfaisal, Adwaa Alamri, Volkan Cetinkaya, Nahar Alazmi","doi":"10.1080/07317115.2025.2505577","DOIUrl":"https://doi.org/10.1080/07317115.2025.2505577","url":null,"abstract":"<p><strong>Objectives: </strong>Proponents of integrated healthcare systems suggest that such system can improve healthcare experience for individuals with dementia by amalgamating personal and structured resources.</p><p><strong>Methods: </strong>We assessed systematically available evidence on the current state of integrated healthcare systems viewed in terms of different levels and dimensions of integration, emphasizing multiple stakeholders' simultaneous perspectives. Studies were eligible for inclusion if they (1) evaluated a health system, (2) adopted a network or integrated care model, (3) cared for individuals with dementia, and (4) provided real-world data.</p><p><strong>Results: </strong>Our review included 31 studies. Main components of the healthcare system included care mediation, multidisciplinary care, primary care integration, long-term care, community-based service, digital technology, and one undefined. Most studies involved meso-level integration (<i>n</i> = 23), followed by micro-level (<i>n</i> = 12) and macro-level integration (<i>n</i> = 5).</p><p><strong>Conclusions: </strong>Key factors that promote an integrated healthcare system for dementia include supportive organizational structure, multidisciplinary collaboration, effective leadership, clear roles, streamlined referral, and community involvement. Macro-level integration should be considered with greater emphasis in conjunction with both meso- and micro-level integration.</p><p><strong>Clinical implications: </strong>Successful development of comprehensive integrated healthcare network will require thoughtful implementation and transition across all levels of the system.</p>","PeriodicalId":10376,"journal":{"name":"Clinical Gerontologist","volume":" ","pages":"1-17"},"PeriodicalIF":2.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mental Health Consequences of Age-Related Macular Degeneration: Exploring Depression Prevalence and Severity in Wet and Dry Forms.","authors":"Nikolaos Gouliopoulos, Nikolaos Bouratzis, Stylianos Kympouropoulos, Ioannis Datseris, Ilias Georgalas, Panagiotis Theodossiadis, Alexandros Rouvas","doi":"10.1080/07317115.2025.2506768","DOIUrl":"https://doi.org/10.1080/07317115.2025.2506768","url":null,"abstract":"<p><strong>Objectives: </strong>Age-related macular degeneration (AMD) is a leading cause of vision loss, affecting quality of life. Although AMD is associated with an increased risk of depression, differences between dry and wet forms are not well understood. This study examined depressive symptoms in Greek patients with dry and wet AMD compared to healthy-controls using the Zung Self-Rating Depression Scale (SDS).</p><p><strong>Methods: </strong>A cross-sectional study included 146 AMD patients (74 dry, 72 wet) and 60 controls. Depressive symptoms were assessed using the Zung SDS. Demographic and clinical data were collected. Statistical analyses compared depression severity and prevalence between groups, adjusting for potential confounders.</p><p><strong>Results: </strong>Wet AMD patients had significantly higher Zung SDS scores (50.4 ± 7.81) than dry AMD (44.8 ± 6.75) and controls (41.4 ± 7.85, <i>p</i> < .001). Depression prevalence was 56% in wet, 27% in dry AMD, and 20% in controls. After adjusting for visual acuity, age, sex, and other factors, wet AMD remained significantly associated with greater depression severity (<i>p</i> < .001).</p><p><strong>Conclusions: </strong>Wet AMD is associated with higher depression severity compared to dry AMD, emphasizing the need for integrated ophthalmologic and mental health care.</p><p><strong>Clinical implications: </strong>Depression is common among AMD patients, particularly those with wet AMD. Screening and psychological support should be incorporated into AMD management.</p>","PeriodicalId":10376,"journal":{"name":"Clinical Gerontologist","volume":" ","pages":"1-9"},"PeriodicalIF":2.6,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Exergame Intervention on Depressive Symptoms, Daily Living Activities, and Fear of Falling in Older Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Sholeh Khodadad Kashi, Vahid Saatchian","doi":"10.1080/07317115.2025.2503250","DOIUrl":"https://doi.org/10.1080/07317115.2025.2503250","url":null,"abstract":"<p><strong>Objectives: </strong>This systematic review evaluated exergame interventions' efficacy in older adults, focusing on depressive symptoms, activities of daily living (ADLs), and fear of falling.</p><p><strong>Methods: </strong>We searched five electronic databases from inception to June 2024. Data were synthesized using the inverse-variance method, reporting standardized mean differences (SMDs) with 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Twenty-four randomized controlled trials (RCTs) with 1,128 participants were included. Exergames significantly improved depressive symptoms (SMD = -0.76, 95% CI: -1.11 to -0.40, <i>p</i> < .001). Meta-regression showed no influence of sample size, health status, intervention duration, gender, or gaming device. No significant effects were found for ADLs (SMD = 0.01, 95% CI: -0.75 to 0.76, <i>p</i> = .988) or fear of falling (SMD = -0.16, 95% CI: -0.40 to 0.08, <i>p</i> = .189).</p><p><strong>Conclusions: </strong>Exergames enhance mental health in older adults but lack clear effects on physical function or fear of falling. High-quality, long-term studies are needed.</p><p><strong>Clinical implications: </strong>Exergames offer an engaging intervention to reduce depressive symptoms, complementing mental health therapies. Clinicians should use modern platforms and combine exergames with physical or behavioral interventions to address ADLs and fear of falling.</p>","PeriodicalId":10376,"journal":{"name":"Clinical Gerontologist","volume":" ","pages":"1-15"},"PeriodicalIF":2.6,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}