Circulation最新文献

{"title":"CXCL12 Derived From ACKR1⁺ Intraplaque Neovessels Mediates CD8⁺ T Cell Recruitment in Human Atherosclerosis.","authors":"Laura Parma, Nadja Sachs, Nikola Sobczak, Zhaolong Li, Kevin Merchant, Jessica Pauli, Marie A C Depuydt, Anouk Wezel, Harm J Smeets, Ilze Bot, Bram Slütter, Lars Maegdefessel, Christian Weber, Johan Duchêne, Remco T A Megens","doi":"10.1161/CIRCULATIONAHA.124.072560","DOIUrl":"https://doi.org/10.1161/CIRCULATIONAHA.124.072560","url":null,"abstract":"","PeriodicalId":10331,"journal":{"name":"Circulation","volume":"151 8","pages":"581-584"},"PeriodicalIF":35.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital Twins: The Future for Ventricular Tachycardia Ablation?","authors":"Dingxin Qin, Jagmeet P Singh","doi":"10.1161/CIRCULATIONAHA.124.072299","DOIUrl":"https://doi.org/10.1161/CIRCULATIONAHA.124.072299","url":null,"abstract":"","PeriodicalId":10331,"journal":{"name":"Circulation","volume":"151 8","pages":"534-536"},"PeriodicalIF":35.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highlights From the <i>Circulation</i> Family of Journals.","authors":"","doi":"10.1161/CIRCULATIONAHA.125.073856","DOIUrl":"https://doi.org/10.1161/CIRCULATIONAHA.125.073856","url":null,"abstract":"","PeriodicalId":10331,"journal":{"name":"Circulation","volume":"151 8","pages":"568-573"},"PeriodicalIF":35.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Update on Diagnosis and Management of Kawasaki Disease: A Scientific Statement From the American Heart Association.","authors":"","doi":"10.1161/CIR.0000000000001313","DOIUrl":"https://doi.org/10.1161/CIR.0000000000001313","url":null,"abstract":"","PeriodicalId":10331,"journal":{"name":"Circulation","volume":"151 8","pages":"e677-e679"},"PeriodicalIF":35.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"State of the Heart (and Brain) in 2025.","authors":"Dhruv S Kazi","doi":"10.1161/CIRCULATIONAHA.125.073826","DOIUrl":"10.1161/CIRCULATIONAHA.125.073826","url":null,"abstract":"","PeriodicalId":10331,"journal":{"name":"Circulation","volume":" ","pages":"515-517"},"PeriodicalIF":35.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highlights From the <i>Circulation</i> Family of Journals.","authors":"","doi":"10.1161/CIRCULATIONAHA.125.073856","DOIUrl":"https://doi.org/10.1161/CIRCULATIONAHA.125.073856","url":null,"abstract":"","PeriodicalId":10331,"journal":{"name":"Circulation","volume":"151 8","pages":"568-573"},"PeriodicalIF":35.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Abstract 4139303: Temporal Trends in Cardiovascular Risk Factors and Cardiovascular Disease among Middle Eastern Immigrants in the National Health Interview Survey 2004-2018.","authors":"","doi":"10.1161/CIR.0000000000001311","DOIUrl":"https://doi.org/10.1161/CIR.0000000000001311","url":null,"abstract":"","PeriodicalId":10331,"journal":{"name":"Circulation","volume":"151 8","pages":"e680"},"PeriodicalIF":35.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personalized Heart Digital Twins Detect Substrate Abnormalities in Scar-Dependent Ventricular Tachycardia.","authors":"Michael C Waight, Adityo Prakosa, Anthony C Li, Nick Bunce, Anna Marciniak, Natalia A Trayanova, Magdi M Saba","doi":"10.1161/CIRCULATIONAHA.124.070526","DOIUrl":"10.1161/CIRCULATIONAHA.124.070526","url":null,"abstract":"<p><strong>Background: </strong>Current outcomes from catheter ablation for scar-dependent ventricular tachycardia (VT) are limited by high recurrence rates and long procedure durations. Personalized heart digital twin technology presents a noninvasive method of predicting critical substrate in VT, and its integration into clinical VT ablation offers a promising solution. The accuracy of the predictions of digital twins to detect invasive substrate abnormalities is unknown. We present the first prospective analysis of digital twin technology in predicting critical substrate abnormalities in VT.</p><p><strong>Methods: </strong>Heart digital twin models were created from 18 patients with scar-dependent VT undergoing catheter ablation. Contrast-enhanced cardiac magnetic resonance images were used to reconstruct finite-element meshes, onto which regional electrophysiological properties were applied. Rapid-pacing protocols were used to induce VTs and to define the VT circuits. Predicted optimum ablation sites to terminate all VTs in the models were identified. Invasive substrate mapping was performed, and the digital twins were merged with the electroanatomical map. Electrogram abnormalities and regions of conduction slowing were compared between digital twin-predicted sites and nonpredicted areas.</p><p><strong>Results: </strong>Electrogram abnormalities were significantly more frequent in digital twin-predicted sites compared with nonpredicted sites (468/1029 [45.5%] versus 519/1611 [32.2%]; <i>P</i><0.001). Electrogram duration was longer at predicted sites compared with nonpredicted sites (82.0±25.9 milliseconds versus 69.7±22.3 milliseconds; <i>P</i><0.001). Digital twins correctly identified 21 of 26 (80.8%) deceleration zones seen on isochronal late activation mapping.</p><p><strong>Conclusions: </strong>Digital twin-predicted sites display a higher prevalence of abnormal and prolonged electrograms compared with nonpredicted sites and accurately identify regions of conduction slowing. Digital twin technology may help improve substrate-based VT ablation.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT04632394.</p>","PeriodicalId":10331,"journal":{"name":"Circulation","volume":" ","pages":"521-533"},"PeriodicalIF":35.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Abstract 4139285: Awareness of Myocardial Infarction and Stroke Symptoms Among Asian American Adults: Insights from the National Health Interview Survey 2014 and 2017.","authors":"","doi":"10.1161/CIR.0000000000001312","DOIUrl":"https://doi.org/10.1161/CIR.0000000000001312","url":null,"abstract":"","PeriodicalId":10331,"journal":{"name":"Circulation","volume":"151 8","pages":"e681"},"PeriodicalIF":35.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing and Addressing Cardiovascular and Obstetric Risks in Patients Undergoing Assisted Reproductive Technology: A Scientific Statement From the American Heart Association.","authors":"Rina Mauricio, Garima Sharma, Jennifer Lewey, Rose Tompkins, Torie Plowden, Kathryn Rexrode, Mary Canobbio, Jenna Skowronski, Afshan Hameed, Candice Silversides, Harmony Reynolds, Arthur Vaught","doi":"10.1161/CIR.0000000000001292","DOIUrl":"10.1161/CIR.0000000000001292","url":null,"abstract":"<p><p>The use of assisted reproductive technology (ART) is growing, both to assist individuals with infertility and for fertility preservation. Individuals with cardiovascular disease (CVD), or risk factors for CVD, are increasingly using ART. Thus, knowing how to care for patients undergoing ART is important for the cardiovascular clinician. In this scientific statement, we review the ART process and known short-term and long-term risks associated with ART that can adversely affect patients with CVD. We review current knowledge on risks from ART for specific cardiac conditions and provide a suggested approach to evaluating and counseling patients with CVD contemplating ART as well as suggested management before and during the ART process. Individuals with CVD are at increased risk for pregnancy complications, and management of this unique population has been discussed previously. The focus of this scientific statement is on ART. Therefore, discussions on risk assessment, counseling, and management of individuals with CVD during pregnancy are limited, and established guidelines are referenced.</p>","PeriodicalId":10331,"journal":{"name":"Circulation","volume":" ","pages":"e661-e676"},"PeriodicalIF":35.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}