Circulation: Cardiovascular Interventions最新文献

{"title":"Novel Application of a Familiar Concept: TR Proportionality and T-TEER Outcomes.","authors":"Jonathan E Labin, Serge Harb, Grant W Reed","doi":"10.1161/CIRCINTERVENTIONS.126.016819","DOIUrl":"https://doi.org/10.1161/CIRCINTERVENTIONS.126.016819","url":null,"abstract":"","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016819"},"PeriodicalIF":7.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision Antiplatelet Therapy: The Promise and Complexity of Pharmacogenomic Antiplatelet Therapy.","authors":"Carine E Hamo, Jeffrey S Berger","doi":"10.1161/CIRCINTERVENTIONS.126.016678","DOIUrl":"https://doi.org/10.1161/CIRCINTERVENTIONS.126.016678","url":null,"abstract":"","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016678"},"PeriodicalIF":7.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Impact of Renal Function on Outcomes After Physiology-Guided Coronary Revascularization: Insights From the J-PRIDE Registry.","authors":"Hirofumi Ohashi, Shoichi Kuramitsu, Hirohiko Ando, Tomohiro Shinozaki, Yoshiaki Kawase, Takenori Domei, Futoshi Yamanaka, Umihiko Kaneko, Tsunekazu Kakuta, Kazunori Horie, Hidenobu Terai, Yasutsugu Shiono, Toru Tagashira, Kazutaka Nogi, Takashi Kubo, Taku Asano, Jun Shiraishi, Hiromasa Otake, Akinori Sugano, Hiroki Okabe, Atsushi Iwai, Yuetsu Kikuta, Hidetaka Nishina, Masashi Iwabuchi, Hiroyoshi Yokoi, Takashi Akasaka, Hitoshi Matsuo, Nobuhiro Tanaka, Tetsuya Amano","doi":"10.1161/CIRCINTERVENTIONS.125.016454","DOIUrl":"https://doi.org/10.1161/CIRCINTERVENTIONS.125.016454","url":null,"abstract":"<p><strong>Background: </strong>The clinical utility of physiology-guided revascularization for decision-making in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) remains uncertain. The aim of this study is to evaluate the diagnostic performance and prognostic significance of fractional flow reserve (FFR) and nonhyperemic pressure ratios (NHPRs) according to the severity of CKD.</p><p><strong>Methods: </strong>This subanalysis of the J-PRIDE registry, a prospective multicenter study conducted at 20 Japanese centers between September 2019 and February 2021, included 4296 lesions from 3194 patients who underwent both FFR and NHPR assessment. Patients were categorized by estimated glomerular filtration rate into non-CKD (≥60 mL/min per 1.73 m²; n=1639), CKD (15-59; n=1321), and ESRD (<15 or on dialysis; n=234). The primary end point was 1-year target vessel failure, defined as a composite of cardiac death, target vessel myocardial infarction, and clinically driven target vessel revascularization.</p><p><strong>Results: </strong>The 1-year incidence of target vessel failure was significantly higher in the ESRD group than in CKD and non-CKD groups (8.4% versus 2.4% and 2.6%; for CKD, adjusted hazard ratio, 3.09 [95% CI, 1.60-5.96]; <i>P</i><0.001; for non-CKD, adjusted hazard ratio, 2.88 [95% CI, 1.98-5.47]; <i>P</i>=0.001). The NHPR cutoff predicting FFR ≤0.80 was lower in ESRD compared with CKD and non-CKD (0.85 versus 0.89 versus 0.89). Although the overall prevalence of FFR/NHPR discordance was comparable (23.6%, 19.7%, and 19.7%; <i>P</i>=0.24), FFR-/NHPR+ discordance predominated in ESRD (18.6% versus 9.3% versus 7.0%; <i>P</i><0.001). FFR-/NHPR+ lesions in the ESRD group exhibited an excess risk compared with other lesions. Revascularization was beneficial in non-CKD patients with FFR+/NHPR- lesions, whereas no clear benefit was observed in patients with CKD and ESRD.</p><p><strong>Conclusions: </strong>Patients with ESRD exhibited distinct physiological characteristics and substantially worse outcomes, highlighting the need for tailored coronary revascularization strategies in this population.</p><p><strong>Registration: </strong>URL: https://www.umin.ac.jp/ctr; Unique identifier: UMIN000038403.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016454"},"PeriodicalIF":7.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Durability of Bioprosthetic and Mechanical Valves Implanted for Aortic Valve Replacement in Pediatric Patients.","authors":"Rumi Yokota, Yulin Zhang, Ayush Jaggi, Tristan Perry, Elisabeth Martin, Michael Ma, Rajesh Punn, Frank L Hanley, Doff B McElhinney","doi":"10.1161/CIRCINTERVENTIONS.125.015931","DOIUrl":"https://doi.org/10.1161/CIRCINTERVENTIONS.125.015931","url":null,"abstract":"<p><strong>Background: </strong>There is limited published information on bioprosthetic aortic valve durability. The purpose of this study was to assess the durability of bioprosthetic valves used for aortic valve replacement (AVR) in pediatric patients.</p><p><strong>Methods: </strong>We reviewed all surgical AVR procedures performed from May 02 to July 24 in patients ≤21 years of age using a mechanical valve or bioprosthesis. Long-term valve-related outcomes were assessed with propensity-score-adjusted analysis.</p><p><strong>Results: </strong>During the study period, 180 AVR procedures were performed in pediatric patients (median age, 14.3 years) using a bioprosthetic valve (n=79) or mechanical prosthesis (n=101). Freedom from reintervention was significantly shorter in patients with a bioprosthetic valve (77% at 5 years, 29% at 10 years) than those with a mechanical valve (88% at 5 years, 82% at 10 years; <i>P</i><0.001). By propensity score-adjusted multivariable Cox regression, a bioprosthetic valve (hazard ratio, 4.66 [95% CI, 2.26-9.62]; <i>P</i><0.001) and age <12 years at AVR (3.26 [1.81-5.87]; <i>P</i><0.001) were associated with shorter freedom from reintervention. Endocarditis was diagnosed in 16 patients, and thromboembolic or bleeding complications were reported in 8.</p><p><strong>Conclusions: </strong>In pediatric patients undergoing AVR, bioprosthetic valves have significantly worse durability than mechanical prostheses, with the disparity most pronounced in younger patients. Valve-related mortality and complications were relatively common. These findings should focus attention on the need for better replacement valves or therapeutic options in young patients with aortic valve disease.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e015931"},"PeriodicalIF":7.4,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Structural Complications in TAVR: A Persistent Challenge in the Modern Era.","authors":"R David Anderson, Faiz Ali Saulat","doi":"10.1161/CIRCINTERVENTIONS.126.016550","DOIUrl":"https://doi.org/10.1161/CIRCINTERVENTIONS.126.016550","url":null,"abstract":"","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016550"},"PeriodicalIF":7.4,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147728664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultra-Low-Dose Noise-Free Technology to Reduce Radiation Exposure During Coronary Angiography.","authors":"Jinying Zhou, Qiyu Zhang, Hao Lu, Yizhe Wu, Li Shen, Jianying Ma, Rende Xu, Feng Zhang, Zhangwei Chen, Juying Qian, Chenguang Li, Junbo Ge","doi":"10.1161/CIRCINTERVENTIONS.126.016542","DOIUrl":"https://doi.org/10.1161/CIRCINTERVENTIONS.126.016542","url":null,"abstract":"<p><strong>Background: </strong>Percutaneous coronary intervention (PCI) is a cornerstone treatment for coronary artery disease. As procedural volumes continue to rise, the associated radiation risk from angiography systems has drawn increasing concern. Thus, we developed a novel ultra-low-dose Noise-Free technology to optimize angiography systems. This study aims to investigate whether it effectively reduces radiation exposure in real-world coronary interventions.</p><p><strong>Methods: </strong>A comparative study on a single-center, real-world, observational cohort. The primary end point was an intergroup comparison of procedural radiation exposure, including dose area product, air kerma, and dose rate, stratified by exposure mode (fluoroscopy or cine) and procedure type (diagnostic coronary angiography, single-vessel PCI, or chronic total occlusion PCI). The secondary end point included an expert semi-quantitative assessment and a quantitative contrast-to-noise ratio for image quality.</p><p><strong>Results: </strong>A total of 380 procedures (102 coronary angiography, 78 single-vessel PCI, and 200 chronic total occlusion PCI) were performed in 380 patients using 4 different angiography systems. There was no significant difference in baseline patient characteristics, procedural time, or operator experience. In coronary angiography procedures, the ultra-low-dose technique demonstrated a total air kerma of 60.3 (38.5-74.1) mGy, total dose area product of 4.0 (2.9-5.2) Gy·cm², fluoroscopy dose rate of 7.9 (6.0-9.6) mGy/min, and cine dose rate of 51.7 (37.4-64.9) mGy/min, corresponding to 40% to 70%, 37% to 66%, 16% to 62%, and 25% to 79% reductions than others, respectively. Similar radiation reductions were observed for single-vessel PCI. For chronic total occlusion PCI, the corresponding percentages of radiation reduction in total air kerma, total dose area product, fluoroscopy dose rate, and cine dose rate were 59% to 73%, 54% to 69%, 22% to 64%, and 60% to 79%, respectively, relative to the other 3 systems. The semi-quantitative assessment and contrast-to-noise ratio analysis showed comparable image quality between the 4 systems.</p><p><strong>Conclusions: </strong>The Noise-Free technique reduced radiation exposure across cumulative and rate metrics while preserving diagnostic image quality, with the greatest reduction observed in complex cases. These findings support its clinical utility for lowering radiation risk.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016542"},"PeriodicalIF":7.4,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147728711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of TAVR Failure Mechanism on Outcomes After Reintervention: From the EXPLANTORREDO-TAVR Registry.","authors":"Bhavandhar Penta, Gilbert H L Tang, Mohamed Abdel-Wahab, Rik Adrichem, Hasan Ahmad, Martin Andreas, Anita W Asgar, Igor Belluschi, Walid Ben-Ali, Oliver Bhadra, Anson Cheung, Andrea Colli, Lenard Conradi, Silvia Corona, Ole De Backer, Paolo Denti, Nimesh D Desai, Marco Di Eusanio, J Michael DiMaio, John K Forrest, Shinichi Fukuhara, Arnar Geirsson, Sachin S Goel, Joshua B Goldberg, Christian Hagl, Howard C Herrmann, Thijmen W Hokken, Jorg Kempfert, Philipp Kiefer, Neal S Kleiman, Chad A Kliger, Markus Mach, Mateo Marin-Cuartas, David Meier, Thomas Modine, George Petrossian, Luigi Pirelli, Basel Ramlawi, Newell Robinson, Joshua D Rovin, Hendrik Ruge, Shekhar Saha, Christian C Schults, Emily Shih, Molly Szerlip, Maurizio Taramasso, Axel Unbehaun, Nicolas Van Mieghem, Keti Vitanova, Ron Waksman, Lin Wang, John G Webb, Moritz Wyler von Ballmoos, Michael J Reardon, Tamim N Nazif, Martin B Leon, Michael J Mack, Tsuyoshi Kaneko, Vinayak N Bapat, Syed Zaid","doi":"10.1161/CIRCINTERVENTIONS.125.016068","DOIUrl":"https://doi.org/10.1161/CIRCINTERVENTIONS.125.016068","url":null,"abstract":"<p><strong>Background: </strong>As transcatheter aortic valve replacement (TAVR) expands to patients with longer life expectancy, the impact of failure mechanisms on outcomes of TAVR-explant and redo-TAVR remains uncertain. We sought to evaluate outcomes of TAVR reintervention based on the failure mechanism of the index transcatheter aortic valve.</p><p><strong>Methods: </strong>From 2009 to 2022, 553 patients from 29 centers in the EXPLANTORREDO-TAVR registry underwent TAVR-explant or redo-TAVR for transcatheter aortic valve failure. Patients with endocarditis were excluded. Patients with structural valve deterioration (SVD, N=224 [64.9%]) were compared with those with nonstructural valve dysfunction (NSVD, N=121 [35.1%]), comprising paravalvular leak (86.0%) and prosthesis-patient mismatch (14.0%). Outcomes were assessed at 30 days and 1 year.</p><p><strong>Results: </strong>Mean age was 75.6±9.3 years, with 42% women. There were no differences in reintervention type between groups (redo-TAVR in 58.0% SVD versus 49.6% NSVD; TAVR-explant: 42.0% versus 50.4%; <i>P</i>=0.14). Compared with NSVD, SVD was the predominant mode of failure in balloon-expandable valves (50.7% versus 24.8%; <i>P</i><0.001), had a longer time to reintervention (50.7 versus 5.5 months; <i>P</i><0.001), and favored non-balloon-expandable valves at redo-TAVR (56.9% versus 33.3%; <i>P</i>=0.003). Mortality at 30 days and 1 year did not differ significantly between SVD and NSVD for either redo-TAVR (30 days: 3.2% versus 1.7%, <i>P</i>=1.00; 1 year: 18.0% versus 12.0%; <i>P</i>=0.47) or TAVR-explant (30 days: 16.3% versus 12.1%, <i>P</i>=0.63; 1 year: 40.0% versus 29.5%; <i>P</i>=0.39). There were also no differences in risk-adjusted 3-year cumulative mortality between groups (redo-TAVR: HR, 1.30 [95% CI, 0.68-2.46], <i>P</i>=0.43 [ref=NSVD]; TAVR-explant: HR, 1.24 [95% CI, 0.64-2.41]; <i>P</i>=0.53).</p><p><strong>Conclusions: </strong>SVD and NSVD failures had distinct valve types and reintervention timing, with SVD having a longer time to TAVR reintervention, but the failure mechanism did not impact reintervention type or clinical outcomes.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016068"},"PeriodicalIF":7.4,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147688662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemodynamic and Clinical Outcomes of Transcatheter Valve Expansion in Degenerated Mitral Bioprostheses.","authors":"Mark J Zorman, Kaleb Foster, Bas L Kietselaer, Mayra E Guerrero, Charanjit S Rihal, Mackram F Eleid","doi":"10.1161/CIRCINTERVENTIONS.125.016270","DOIUrl":"https://doi.org/10.1161/CIRCINTERVENTIONS.125.016270","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter mitral valve-in-valve replacement is an established therapy for intermediate and high-risk patients with degenerated bioprostheses, but restricted transcatheter valve (THV) expansion within rigid surgical frames and elevated gradients have raised durability concerns. This study aimed to evaluate midterm outcomes of mitral valve-in-valve patients according to THV expansion and sizing strategy.</p><p><strong>Methods: </strong>Patients who underwent mitral valve-in-valve with balloon-expandable valves at Mayo Clinic Rochester between 2014 and 2023 were retrospectively analyzed. THV expansion (inflow, waist, outflow) was measured from procedural fluoroscopy and indexed to nominal size, with zero indicating expansion to nominal dimensions. Median index values were used as subgroup cutoffs to compare the incidence of the primary composite outcome of all-cause mortality, heart failure readmission, and valve reintervention.</p><p><strong>Results: </strong>The analysis included 80 patients with a median follow-up of 2.5 years. A total of 53 (66%) valves were underexpanded across all 3 diameters, with median inflow, waist, and outflow expansion indices of -10.2, -16.2, and -3.2, respectively. Across all indices, THV expansion closer to nominal size was associated with lower rates of the primary outcome (<i>P</i><0.05). Greater expansion correlated with a larger mitral valve area and lower transvalvular mean gradient. Oversized THVs were significantly less expanded and had a higher incidence of the primary composite outcome compared with recommended-size THVs (<i>P</i>=0.02).</p><p><strong>Conclusions: </strong>THV underexpansion in degenerated mitral bioprostheses is common and associated with elevated gradients and worse midterm outcomes. Further research is warranted to define THV expansion targets to improve midterm outcomes following mitral valve-in-valve intervention.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016270"},"PeriodicalIF":7.4,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter by Skalidis et al Regarding Article, \"Angiography-Derived Fractional Flow Reserve During Percutaneous Coronary Intervention\".","authors":"Ioannis Skalidis, Stephane Cook, Mario Togni","doi":"10.1161/CIRCINTERVENTIONS.126.016774","DOIUrl":"https://doi.org/10.1161/CIRCINTERVENTIONS.126.016774","url":null,"abstract":"","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016774"},"PeriodicalIF":7.4,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transeptal Mitral Annuloplasty With the AMEND System: 6-Month Results of First in Man Cohort.","authors":"Bruno Melica, Shemy Carasso, Adi Butnaru, Irakli Gogorishvili, Mikhael Metreveli, Thomas Modine, Levan Kurashvili, Rivka Farkash, David Meerkin","doi":"10.1161/CIRCINTERVENTIONS.125.015977","DOIUrl":"https://doi.org/10.1161/CIRCINTERVENTIONS.125.015977","url":null,"abstract":"<p><strong>Background: </strong>The AMEND implant is a semi-rigid closed D-shaped annuloplasty ring deployed through a transvenous transeptal approach. It is aimed to affect selective anteroposterior dimensional reduction, improving leaflet coaptation, and reduce mitral regurgitation (MR). We report the 6-month outcomes of the first cohort treated.</p><p><strong>Methods: </strong>Thirteen patients with the grade 3 or 4 functional MR were treated in 2 studies in Georgia and Israel, and with compassionate approvals in Portugal and France. They underwent mitral repair with the AMEND annuloplasty and were followed for 6 months.</p><p><strong>Results: </strong>There were no deaths, myocardial infarctions, strokes or cardiac surgery. There were 2 pericardial effusions, 1 acute and the second at 4 months. There was no anchor disengagement or device dehiscence over the follow-up period. There was a single patient who was readmitted with heart failure, and the iatrogenic atrial septal defect was closed. At 6 months the overall anteroposterior dimensional reduction achieved acutely was maintained, with MR reduction being stable, with 11 of 13 patients with ≤grade 1 MR.</p><p><strong>Conclusions: </strong>In this small multicenter cohort of patients, the AMEND annuloplasty procedure demonstrated promising safety, with stable and significant reduction of MR maintained over the 6-month follow-up period.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e015977"},"PeriodicalIF":7.4,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}