Circulation: Cardiovascular Interventions最新文献

{"title":"Response by Sotomi and Nakamura to Letter Regarding Article, \"Optical Coherence Tomography Characterization of Coronary Lithotripsy Following Atherectomy for Treatment of Severely Calcified Lesions\".","authors":"Yohei Sotomi, Masato Nakamura","doi":"10.1161/CIRCINTERVENTIONS.126.017430","DOIUrl":"10.1161/CIRCINTERVENTIONS.126.017430","url":null,"abstract":"","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e017430"},"PeriodicalIF":7.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148966876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug-Coated Balloons for Side-Branch Treatment in Coronary Bifurcations: Ready for Prime Time?","authors":"Arman Qamar, Binita Shah","doi":"10.1161/CIRCINTERVENTIONS.126.017233","DOIUrl":"10.1161/CIRCINTERVENTIONS.126.017233","url":null,"abstract":"","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e017233"},"PeriodicalIF":7.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149079805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary Atresia With Intact Septum Survival, Reintervention, and Days in Hospital Through Childhood: Contemporary Outcomes From a National Registry.","authors":"Dan-Mihai Dorobantu, Qi Huang, Ferran Espuny-Pujol, Katherine L Brown, Sok-Leng Kang, Asmita Singhania, Rodney C Franklin, Sonya Crowe, Christina Pagel, Serban C Stoica","doi":"10.1161/CIRCINTERVENTIONS.125.016435","DOIUrl":"10.1161/CIRCINTERVENTIONS.125.016435","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary atresia with intact ventricular septum management has evolved, with increased use of transcatheter right ventricular decompression, but the impact on contemporary outcomes remains unknown. This study evaluates contemporary national outcomes in patients aged 0 to 18 years.</p><p><strong>Methods: </strong>Patients with pulmonary atresia with intact ventricular septum undergoing cardiac intervention (2000-2022) in England and Wales were linked to multiple national data sets. Mortality (early and late), reintervention, and hospital stay were described overall and by treatment pathway.</p><p><strong>Results: </strong>Among 488 included patients with pulmonary atresia with intact ventricular septum, 58.8% underwent right ventricular decompression as the first procedure, predominantly transcatheter (84.8%), while 32.4% received stage 1 palliation (arteriopulmonary shunt or ductal stenting), and 8.8% died or were lost to follow-up before either intervention. Overall, 54.5% achieved biventricular (BiV) repair, 26.7% underwent functionally single-ventricle palliation, and 18.8% were noncommitted. Overall group in-hospital mortality was 11.7%. The median follow-up was 8.9 years, with 1- and 5-year mortality of 19.8% (95% CI, 16.2%-23.2%) and 20.8% (95% CI, 17.1%-24.4%), respectively. Stage 1 palliation as the initial therapy had higher 1-year mortality than right ventricular decompression (37.2% [29.0%-44.5%] versus 7.7% [4.5%-10.7%]). Cardiac reintervention was 62.6% (56.1%-68.4%) at 10 years after BiV repair and 32.8% (21.5%-44.4%) at 10 years after palliative stage 3. Median hospital stay was greatest in the first year (35 days), declining to 2 days annually by 10 years, with functionally single-ventricle patients requiring more days in hospital than BiV patients (52 versus 28).</p><p><strong>Conclusions: </strong>In a contemporary pulmonary atresia with intact ventricular septum cohort, transcatheter right ventricular decompression was the predominant initial intervention. This approach had lower in-hospital mortality compared with older multicenter series, with BiV repair achieved in more than half of the patients. Early mortality after nonantegrade flow augmentation remains high, likely due to nonmodifiable risk factors in severe cases. Long-term survival and hospital stay remain better for those amenable to BiV circulation, reflecting more favorable anatomy compared with those on the single-ventricle pathway, although reintervention is lower in the latter.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016435"},"PeriodicalIF":7.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148758682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National Improvement in Radial Access Experience.","authors":"Tayyab Shah, Ashwin Nathan","doi":"10.1161/CIRCINTERVENTIONS.126.017396","DOIUrl":"10.1161/CIRCINTERVENTIONS.126.017396","url":null,"abstract":"","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e017396"},"PeriodicalIF":7.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149024171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter by Güner et al Regarding Article, \"Optical Coherence Tomography Characterization of Coronary Lithotripsy Following Atherectomy for Treatment of Severely Calcified Lesions\".","authors":"Ahmet Güner, Ezgi Gültekin Güner, Ahmet Yaşar Çizgici","doi":"10.1161/CIRCINTERVENTIONS.126.017362","DOIUrl":"10.1161/CIRCINTERVENTIONS.126.017362","url":null,"abstract":"","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e017362"},"PeriodicalIF":7.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148963154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Drug-Coated Versus Conventional Balloons for the Side Branches of Bifurcation Lesions: OCVC-BIF Study.","authors":"Takayuki Ishihara, Tomoharu Dohi, Daisuke Sakamoto, Hirota Kida, Naotaka Okamoto, Atsushi Kikuchi, Tsutomu Kawai, Naoki Mori, Ryu Shutta, Minoru Ichikawa, Yasunori Ueda, Daisuke Nakamura, Toshiaki Mano, Masami Nishino, Tetsuya Watanabe, Yoshiharu Higuchi, Eisuke Hida, Tomoharu Sato, Shungo Hikoso, Daisaku Nakatani, Yohei Sotomi, Yasushi Sakata","doi":"10.1161/CIRCINTERVENTIONS.125.016424","DOIUrl":"https://doi.org/10.1161/CIRCINTERVENTIONS.125.016424","url":null,"abstract":"<p><strong>Background: </strong>Coronary bifurcation lesions remain one of the most challenging lesions. In particular, satisfactory clinical outcomes have not yet been achieved for side branches. The use of drug-coated balloons (DCBs) has demonstrated acceptable clinical outcomes in native coronary arteries. This study aimed to evaluate the efficacy and safety of additional DCB inflation in the side branches of bifurcation lesions.</p><p><strong>Methods: </strong>The OCVC-BIF study (Comparison of Drug-Coated Versus Conventional Balloons for the Side Branch of Bifurcation Lesions) was conducted as a multicenter, randomized, open-label trial. Patients with bifurcation lesions scheduled for drug-eluting stent (DES) implantation in the main vessel followed by kissing balloon inflation were enrolled in the study. The patients were randomized to receive either additional dilatation of the side branch using a DCB after DES implantation with kissing balloon inflation (DCB group) or only DES implantation with kissing balloon inflation using conventional balloons (non-DCB group). The primary end point was restenosis of the side branch, assessed using scheduled coronary angiography at 9 months or symptom-driven coronary angiography during the 1-year follow-up. Restenosis was defined as ≥50% stenosis of the side branch, determined using 3-dimensional bifurcation quantitative coronary angiography. The key secondary end points included major adverse cardiac events at 12 months, which were defined as a composite of cardiac death, myocardial infarction, clinically driven target lesion revascularization, and stent thrombosis.</p><p><strong>Results: </strong>In total, 299 patients were randomized into the DCB (151 patients) and non-DCB (148 patients) groups between October 2019 and September 2024. Serial 3-dimensional bifurcation quantitative coronary angiography evaluation was performed in 262 (87.6%) patients. The restenosis rate was lower in the DCB group than that in the non-DCB group (8.1% versus 18.3%, <i>P</i>=0.012). However, the incidence of major adverse cardiac events at 12 months was similar between them (10.1% versus 12.4%, <i>P</i>=0.58).</p><p><strong>Conclusions: </strong>Additional DCB inflation in the side branch after main-vessel DES implantation with kissing balloon inflation decreases restenosis in the side branch in the treatment of bifurcation lesions.</p><p><strong>Registration: </strong>URL: https://jrct.mhlw.go.jp/en-latest-detail/jRCTs052200077; Unique identifier: jRCTs052200077.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":"19 10","pages":"e016424"},"PeriodicalIF":7.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149227401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-Year Outcomes of M-TEER With the PASCAL System in Atrial and Ventricular FMR: Insights From the MiCLASP Postmarket Clinical Follow-Up Study.","authors":"Amir A Mahabadi, Tienush Rassaf, Tobias Kister, Thomas Schmitz, Tobias Geisler, Edith Lubos, Jörg Hausleiter, Ingo Eitel, Ralph Stephen von Bardeleben, Sergio Berti, Axel Linke, Christian Hengstenberg, Volker Rudolph, Bernhard Unsöld, Paolo Denti, Stephan Baldus, Georg Nickenig, Helge Möllman, Konstantinos Spargias, Nedy Brambilla, Christian Butter, Wolfgang Rottbauer, Markus Reinthaler, Martin Swaans, Fabien Praz, Adam Witkowski, Nicolas M Van Mieghem, Mamta Buch, Frieder Wolf, Frank Edelmann, Leo Marcoff, Konstantinos Koulogiannis, Philipp Lurz","doi":"10.1161/CIRCINTERVENTIONS.126.016563","DOIUrl":"10.1161/CIRCINTERVENTIONS.126.016563","url":null,"abstract":"<p><strong>Background: </strong>Studies on mitral transcatheter edge-to-edge repair for atrial functional mitral regurgitation (AFMR) and ventricular functional mitral regurgitation (VFMR) are limited.</p><p><strong>Methods: </strong>We report 1-year outcomes of mitral transcatheter edge-to-edge repair for AFMR and VFMR using the PASCAL transcatheter valve repair system in the MiCLASP (Transcatheter Repair of Mitral Regurgitation With Edwards Pascal Transcatheter Valve Repair System) multicenter European postmarket clinical follow-up study.</p><p><strong>Results: </strong>Analysis included 295 patients with FMR (75.5±9.93 years old, 59.3% male) from the first 600 enrolled in the MiCLASP study, with AFMR in 17.6% (52) and VFMR in 82.4% (243). Patients with AFMR were older (79.7±6.67 versus 74.6±10.30 years), majority female (75.0% versus 33.3%), and had higher rates of hypertension (98.1% versus 82.3%) and atrial fibrillation (82.7% versus 60.1%) than patients with VFMR (all <i>P</i><0.05). Patients with VFMR had higher NT-proBNP (N-terminal pro-B-type natriuretic peptide) levels (3350 [1720-6564] versus 1562 [790-2286]; <i>P</i><0.001) and more severe mitral regurgitation (≥3+) at baseline (71.9% versus 46.2%; <i>P</i><0.001). Procedural success was high (AFMR, 96.2%; VFMR, 97.1%; <i>P</i>=0.661), and patients with AFMR had shorter procedure duration (73.5 versus 85.5 minutes; <i>P</i>=0.044). One-year Kaplan-Meier estimate of freedom from all-cause mortality or heart failure hospitalization was 79.3% in AFMR and 70.9% in VFMR (<i>P</i>=0.267). Both AFMR and VFMR groups demonstrated significant mitral regurgitation reduction (mitral regurgitation ≤1+, 93.1% and 81.3%), low mean transmitral gradients (3.5 and 3.1 mm Hg), significant proportional reductions in left ventricular end-diastolic volume (-12.9% and -16.4%) and left atrial volume (-9.6% and -10.9%), high proportions at New York Heart Association class I/II (76.5% and 64.6%), and significant increases in Kansas City Cardiomyopathy Questionnaire Overall Summary score (+18.0 and +11.6 points), respectively (all <i>P</i><0.05 from baseline).</p><p><strong>Conclusions: </strong>One-year MiCLASP results support the safety of mitral transcatheter edge-to-edge repair with the PASCAL system in both AFMR and VFMR, with comparable echocardiographic, functional, and quality-of-life changes, despite baseline differences in clinical presentation.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT04430075.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016563"},"PeriodicalIF":7.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Advances in Spontaneous Coronary Artery Dissection.","authors":"Zihan Sun, Yanyan Du, Xin Liu, Haichu Yu","doi":"10.1161/CIRCINTERVENTIONS.126.016831","DOIUrl":"10.1161/CIRCINTERVENTIONS.126.016831","url":null,"abstract":"<p><p>Spontaneous coronary artery dissection (SCAD) is a condition characterized by myocardial injury resulting from the rupture of the coronary artery intima or the formation of an intramural hematoma and is unrelated to atherosclerosis. Recent studies have reported that SCAD accounts for 1% to 4% of cases of acute coronary syndrome in patients, with 90% of these patients being women. The widespread use of intravascular ultrasound and optical coherence tomography has significantly improved the diagnostic sensitivity of SCAD. Currently, specific clinical practice guidelines for SCAD are unavailable, and clinical decision-making relies primarily on observational data and expert recommendations. Therefore, further research on this condition will help guide clinical management and improve patient outcomes. On the basis of previous research findings and case reports, this review summarizes the latest advances in understanding the pathogenesis, pathophysiology, and epidemiology of SCAD, with a focus on clinical diagnostic methods, treatment strategies, and long-term management, thereby providing a reference for future clinical and scientific research.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016831"},"PeriodicalIF":7.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148911080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal Trends and Predictors of Access Site Crossover During PCI in Contemporary Practice: A Report From the NCDR CathPCI Registry.","authors":"Eli Reynolds, Binita Shah, Angel Marks, Daniel Wojdyla, Nathaniel R Smilowitz, Jennifer Rymer, Ian C Gilchrist, Rajiv Gulati, Sunil V Rao","doi":"10.1161/CIRCINTERVENTIONS.126.016673","DOIUrl":"10.1161/CIRCINTERVENTIONS.126.016673","url":null,"abstract":"<p><strong>Background: </strong>Randomized trials comparing radial and femoral access report access site crossover rates of 3% to 9% for radial access and 1% to 3% for femoral access. However, contemporary real-world crossover rates are not well characterized. The aim was to evaluate contemporary trends and predictors of vascular access site crossover during percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>We analyzed index PCI procedures recorded in the National Cardiovascular Data Registry CathPCI (Catheterization and Percutaneous Coronary Intervention) Registry from 2018 to 2024. Access site crossover was identified using documented access data, with radial-to-femoral crossover inferred when the final successful access site was femoral. Temporal trends and clinical predictors of crossover were examined. Operator experience was assessed using cumulative total and radial PCI volumes from 2011 to 2024 as captured in CathPCI Registry versions 4 and 5.</p><p><strong>Results: </strong>Among 3 861 790 index PCIs, 192 902 (5.0%) involved access site crossover, with a modest increase over time. Radial-to-femoral crossover accounted for 81.2% of crossover events. Factors independently associated with crossover included older age, female sex, higher body mass index, and peripheral vascular disease. Operators with the lowest total PCI volume and the lowest radial PCI volume experienced the highest crossover rates. Notably, operators with low radial PCI volume demonstrated a substantial decline in radial-to-femoral crossover over the study period.</p><p><strong>Conclusions: </strong>In contemporary clinical practice, access site crossover rates are consistent with those reported in randomized trials. Although crossover occurs more frequently among lower-volume operators, rates decline with increasing operator experience, supporting the presence of a radial access learning curve and improvement in procedural performance over time.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016673"},"PeriodicalIF":7.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Target Lesion Failure in Patients With In-Stent Restenosis: Insights From the AGENT IDE Trial.","authors":"J Dawn Abbott, Nicholas Kassis, Azeem Latib, Richard A Shlofmitz, Jeffrey W Moses, William B Bachinsky, Suhail Dohad, Steven G Rudick, Robert C Stoler, Brian K Jefferson, William J Nicholson, John D Altman, Cinthia T Bateman, Amar Krishnaswamy, Rafael Cavalcante, Robert W Yeh, Ajay J Kirtane","doi":"10.1161/CIRCINTERVENTIONS.125.016289","DOIUrl":"10.1161/CIRCINTERVENTIONS.125.016289","url":null,"abstract":"<p><strong>Background: </strong>Predictors of target lesion failure (TLF) after percutaneous coronary intervention with drug-coated balloon therapy in patients with in-stent restenosis, as opposed to de novo disease, are limited. This post hoc analysis of the AGENT IDE trial (Agent Paclitaxel-Coated PTCA Balloon Catheter for the Treatment of Subjects With In-Stent Restenosis) aimed to identify predictors of TLF in patients with in-stent restenosis treated with a paclitaxel-coated balloon.</p><p><strong>Methods: </strong>Of the 600 patients with in-stent restenosis in the AGENT IDE trial, 406 were randomized to treatment with the paclitaxel-coated balloon. Among this cohort, demographic, clinical, and core laboratory angiographic data were assessed using a Cox proportional hazards model to identify independent predictors of TLF, defined as the composite occurrence of ischemia-driven target lesion revascularization, target vessel-related myocardial infarction, or cardiac death, at 2-year follow-up.</p><p><strong>Results: </strong>Independent risk factors for 2-year TLF, which occurred in 106 (27.0%) of patients, included multiple stent layers (hazard ratio, 1.80 [95% CI, 1.23-2.65]), White race (hazard ratio, 1.71 [95% CI, 1.03-2.85]), and postlesion preparation in-lesion % diameter stenosis (per 10% increment; hazard ratio, 1.16 [95% CI, 1.03-1.31]). The presence of the target lesion in the left anterior descending artery was associated with a reduced risk of 2-year TLF (hazard ratio, 0.56 [95% CI, 0.36-0.87]).</p><p><strong>Conclusions: </strong>Our findings highlight the variable risk of in-stent restenosis governed by relatively few patient and lesion factors and underscore the significance of optimal lesion preparation before drug-coated balloon therapy as a potentially modifiable factor.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT04647253.</p>","PeriodicalId":10330,"journal":{"name":"Circulation: Cardiovascular Interventions","volume":" ","pages":"e016289"},"PeriodicalIF":7.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148677313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}