Circulation. Arrhythmia and electrophysiology最新文献

{"title":"Postprocedural Anticoagulation After LAAO: Comparing DOACs, Warfarin, and Individual DOAC Agents.","authors":"Yong Hao Yeo, Hermon Kha Kin Wong, Aravinthan Vignarajah, Min Choon Tan, Ramzi Ibrahim, Nishanthi Vigneswaramoorthy, Hicham El-Masry, Justin Z Lee, Dan Sorajja","doi":"10.1161/CIRCEP.125.014599","DOIUrl":"10.1161/CIRCEP.125.014599","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e014599"},"PeriodicalIF":9.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147275811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinct Subdivisions of the Cingulo-Insular Region and Their Role in Modulating the Cardiac Sympathetic-Parasympathetic Balance.","authors":"Yingxuan Li, Na Clara Pan, Cuiping Xu, Liang Qiao, Xueyuan Wang, Wei Shu, Tao Yu, Yuping Wang","doi":"10.1161/CIRCEP.125.013875","DOIUrl":"10.1161/CIRCEP.125.013875","url":null,"abstract":"<p><strong>Background: </strong>The cingulo-insular region is crucial for modulating cardiac activity. However, the distinct roles of its anatomic subdivisions in modulating sympathetic-parasympathetic balance remain poorly defined. We aimed to explore the distinct contributions of subdivisions within the cingulo-insular region to modulating cardio-autonomic balance.</p><p><strong>Methods: </strong>In this prospective observational study, patients with drug-resistant epilepsy undergoing stereo-electroencephalography with electrical cortical stimulation of the cingulo-insular region were enrolled. Stereo-electroencephalography and ECG signals were synchronously recorded during electrical cortical stimulation of the cingulo-insular region. Heart rate variability and R-R interval analyses were conducted to assess cardiac sympathetic-parasympathetic balance. The correlation coefficient between heart rate variability and the strength of phase-amplitude coupling in stereo-electroencephalography was calculated before and after stimulation.</p><p><strong>Results: </strong>Data from 33 patients (70 electrode contacts, 287 trials) were analyzed. Stimulation of the anterior cingulate gyrus enhanced parasympathetic activity, correlated with increased local phase-amplitude coupling strength. The left anterior cingulate gyrus stimulation increased pNN50 (median difference, -5.00% [95% CI, -17.99 to -0.16]; <i>P</i>=0.044); right anterior cingulate gyrus stimulation increased the SD of all normal-to-normal intervals (median difference, -14.22 ms [95% CI, -26.68 to -1.63]; <i>P</i>=0.019) and SD2 (median difference, -19.49 ms [95% CI, -33.26 to -3.22]; <i>P</i>=0.013). Meanwhile, stimulation of the posterior insula significantly reduced the parasympathetic component of heart rate variability and short-term R-R interval. The left posterior insula decreased the SD1/SD2 ratio (median difference, 0.08 [95% CI, 0.03-0.15]; <i>P</i>=0.005); right posterior insula decreased power in the high-frequency range (median difference, 25.30 ms² [95% CI, 3.98-49.35]; <i>P</i>=0.013) and the approximate entropy (median difference, 0.15 [95% CI, 0.04-0.29]; <i>P</i>=0.004).</p><p><strong>Conclusions: </strong>Within the cingulo-insular region, the anterior cingulate gyrus is associated with a relative cardio-parasympathetic dominance, while the posterior insula is linked to a relative cardio-sympathetic dominance. These findings provide a deeper understanding of the neural modulation of cardio-autonomic balance, and may have implications for the prevention and treatment of cardio-autonomic dysfunction in neurological disorders.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013875"},"PeriodicalIF":9.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12994912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147269804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Stratification for a Primary Prevention ICD: Performance of the MADIT-ICD Benefit Score in a Contemporary Real-World Cohort.","authors":"Dillon J Dzikowicz, Anas Jawaid, Michael Christof, Mehmet K Aktas, Alex Nakonechnyi, Valentina Kutyifa, Wojciech Zareba, Bronislava Polonsky, David T Huang, Scott McNitt, Arwa Younis, Ilan Goldenberg","doi":"10.1161/CIRCEP.125.014376","DOIUrl":"10.1161/CIRCEP.125.014376","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e014376"},"PeriodicalIF":9.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147275896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shocking Practices of Pediatric Electrophysiologists: Contemporary Defibrillation Testing Data From a Multicenter National CIED Registry.","authors":"Iqbal El-Assaad, Benjamin H Hammond, Bradley C Clark, Ronn E Tanel, Anne M Dubin, Ian Law, Bradley S Marino, Amy Cassedy, Elizabeth Vickers Saarel, Maully J Shah, Prince J Kannankeril, Soham Dasgupta, Douglas Y Mah","doi":"10.1161/CIRCEP.125.014288","DOIUrl":"10.1161/CIRCEP.125.014288","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e014288"},"PeriodicalIF":9.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147324173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravenous Amiodarone in Preexcited Atrial Fibrillation: A Systematic Review.","authors":"Zain S Ali, David L Nguyen, Abdullah Bhuiyan, Arham S Ali, Abdul Hadi, José Elizardo Llorente Rivadeneira, Amin Meghdadi, Hoshiar Abdollah, Shyla Gupta, William F McIntyre, Adrian Baranchuk","doi":"10.1161/CIRCEP.125.014529","DOIUrl":"10.1161/CIRCEP.125.014529","url":null,"abstract":"<p><p>The current guidelines contraindicate intravenous amiodarone in patients with Wolff-Parkinson-White syndrome presenting with preexcited atrial fibrillation (AF) due to the risk of degeneration into ventricular fibrillation (VF). However, these recommendations are based predominantly on isolated case reports, which is concerning given the drug's widespread global use as a first-line antiarrhythmic in resource-limited settings. To evaluate the safety of intravenous amiodarone in this context, we conducted a systematic review of (1) studies enrolling patients with electrocardiographically confirmed preexcited AF who received intravenous amiodarone and (2) studies quantifying antegrade accessory-pathway effective refractory period during intravenous amiodarone administration. All observational and interventional studies assessing patients with preexcited AF were pooled under a conjugate β-binomial model with prespecified weak priors to estimate the risk of VF during or following infusion. Concomitantly, to assess real-world access to alternative class IIa/IIb European Society of Cardiology-recommended antiarrhythmic agents for preexcited AF, we performed a multinational survey of Latin American emergency departments. Twelve studies comprising 177 patients were included in the review (7 case reports, 2 cohorts, 3 before-and-after interventional studies). Four case reports described transient ventricular rate acceleration or VF following intravenous amiodarone. However, across the observational and interventional cohorts assessing patients with preexcited AF (n=146), no acceleration or VF was observed. The posterior mean estimates of VF risk ranged 0.12% to 0.68% over priors. Across 3 interventional before-and-after studies, there was a significant increase in the anterograde effective refractory period of the atrioventricular node and AP following amiodarone administration. The survey responses from 10 emergency centers indicated that none had access to class IIa/IIb indicated agents, while all had intravenous amiodarone available. Taken together, population-level evidence suggests that the risk of VF in preexcited AF following intravenous amiodarone administration is rare. In settings where guideline-recommended drugs are inaccessible, intravenous amiodarone may represent a clinically reasonable alternative for rhythm or rate control.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e014529"},"PeriodicalIF":9.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147282453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Catheter Configuration on the Mapping of Atrial Fibrillation.","authors":"Miguel Rodrigo, Samuel Ruipérez-Campillo, Prasanth Ganesan, Ruibin Feng, Sanjiv M Narayan","doi":"10.1161/CIRCEP.125.014061","DOIUrl":"10.1161/CIRCEP.125.014061","url":null,"abstract":"<p><strong>Background: </strong>Mapping of heart rhythms is influenced by the size and configuration of the mapping electrodes. Whether a recorded electrogram represents near (local) or remote activity influences diagnosis and treatment, yet is affected by mapping characteristics that are often undefined.</p><p><strong>Methods: </strong>We developed biophysical computational models to predict interactions between the recording tool and cardiac tissue in coherent and disorganized rhythms, which we validated in clinical recordings.</p><p><strong>Results: </strong>Biophysical computational models demonstrated the ability to quantify and visualize the recording antennae for different electrode configurations. Our results show that unipolar electrograms reflected a recording antenna within 3-dimensional ellipsoids of radius 8 mm across-tissue and 2.7 mm transmurally. Bipolar electrogram antennae align with propagation direction in ellipsoids of long axis radius 1.7, 5.7, and 8.3 mm for 2, 5, and 10 mm spacing, respectively, and often extend beyond the physical extent of electrodes. Notably, omnipolar electrograms, constructed from orthogonal bipoles in a triangular configuration, retained some directional preferences of bipolar electrograms, with a complex relationship between electrode orientation and wave direction. When tested clinically on high-resolution, narrow field (grid) catheters and moderate-to-low resolution, global (basket) catheters, antennae varied more with electrode type (correlation coefficient of 0.43 unipolar, 0.05 bipolar, and 0.26 omnipolar; <i>P</i><0.001) and spacing (correlation coefficient of 0.36 versus 0.42; <i>P</i>=0.002) than the precise electrode size.</p><p><strong>Conclusions: </strong>This novel computational-clinical system approach enabled us to systematically compare electrode configurations. This work may help interpret signals in complex biological rhythms, such as atrial fibrillation, and may influence the design of novel catheter configurations and signal processing approaches to identify local tissue signals.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e014061"},"PeriodicalIF":9.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13064552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147303084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right and Left Atrial Dysfunction as Independent Cardiovascular Risk Factors: A UK Biobank Study.","authors":"Vidhushei Yogeswaran, Jennifer A Brody, Colleen M Sitlani, Kerri L Wiggins, Jordan M Prutkin, Joshua C Bis, Eugene Yang, Amil M Shah, Nazem Akoum, Ting Ye, James S Floyd","doi":"10.1161/CIRCEP.125.014412","DOIUrl":"10.1161/CIRCEP.125.014412","url":null,"abstract":"<p><strong>Background: </strong>Atrial cardiopathy often precedes atrial fibrillation (AF) and has emerged as an independent risk factor for cardiovascular outcomes. However, previous studies have been limited in size and have overlooked the right atrium.</p><p><strong>Methods: </strong>In 51 693 UK Biobank participants without prevalent AF, we assessed biatrial volumes and emptying fraction from cardiac magnetic resonance imaging using deep learning segmentation. We evaluated associations with new-onset AF, ischemic stroke, heart failure, and dementia, conducted a genome-wide association study, and evaluated causal associations using Mendelian randomization.</p><p><strong>Results: </strong>Among 51 693 adults, the mean (SD) age was 65 (7.7) years, and 24 584 (48%) were male. During the 4-year follow-up, 964 (1.9%) developed AF, 266 (0.5%) developed ischemic stroke, 365 (0.7%) developed heart failure, and 72 (0.1%) developed dementia. After adjustment for clinical risk factors, both left and right atrial measures were associated with new-onset AF (left atrial minimal volume; hazard ratio, 1.55 [95% CI, 1.48-1.62]), ischemic stroke, and heart failure, with stronger associations in women. Left atrial minimal volume was also associated with dementia. Our genome-wide association study identified 51 (27 novel) genetic associations with atrial measures, many of which do not overlap with established AF loci. Genetic correlations revealed that each atrium had varying correlations with cardiometabolic risk factors, and Mendelian randomization demonstrated that left atrial measures had direct causal effects on AF and stroke risk. However, the stroke associations were attenuated after accounting for AF variants.</p><p><strong>Conclusions: </strong>In this largest assessment of biatrial structure and function to date, both left and right atrial cardiopathies were independently associated with increased risk of adverse cardiovascular events. We identified several novel genetic loci for atrial traits and observed unique genetic correlations between left and right atrial traits and cardiovascular phenotypes, providing insight into chamber-specific remodeling. Several of these measures are likely to be causal determinants of cardiovascular complications previously attributed to AF.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e014412"},"PeriodicalIF":9.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13012265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147303115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arrhythmia-Related Cardiovascular Disease Mortality Among Asian American, Native Hawaiian, and Pacific Islander Groups.","authors":"Vaishnavi Krishnan, Nilay S Shah","doi":"10.1161/CIRCEP.125.014572","DOIUrl":"10.1161/CIRCEP.125.014572","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e014572"},"PeriodicalIF":9.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12975286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147282498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left Ventricular Late Gadolinium Enhancement for Arrhythmic Risk Prediction in ARVC.","authors":"Corrado De Marco, Babken Asatryan, Anneline S J M Te Riele, Andrea Di Marco, Alessio Gasperetti, Antoine Delinière, Jason D Roberts, Henrik K Jensen, Brianna Davies, Andrew D Krahn, Rafik Tadros, Anneli Svensson, Silvia Castelletti, Lia Crotti, Pyotr G Platonov, Karolina Borowiec, Elżbieta K Biernacka, Elena Arbelo, Louis-Philippe David, Ardan M Saguner, Jeff S Healey, Corinna Brunckhorst, Chiara Cappelletto, Davide Stolfo, Marco Merlo, Christine Rootwelt-Norberg, Kristina H Haugaa, Firat Duru, J Peter van Tintelen, Birgitta K Velthuis, Hugh Calkins, Stefan L Zimmerman, Cynthia A James, Laurens P Bosman, Julia Cadrin-Tourigny","doi":"10.1161/CIRCEP.125.014265","DOIUrl":"10.1161/CIRCEP.125.014265","url":null,"abstract":"<p><strong>Background: </strong>The arrhythmogenic right ventricular cardiomyopathy (ARVC) risk calculator estimates the risk of incident sustained ventricular arrhythmia (VA) and performs well in ARVC populations meeting 2010 Task Force Criteria. However, the calculator includes no measure of left ventricular (LV) structure and function, while late gadolinium enhancement (LGE) on cardiac magnetic resonance shows promise in arrhythmic risk prediction. This study aims to evaluate whether LV LGE on cardiac magnetic resonance can further refine ARVC VA risk stratification.</p><p><strong>Methods: </strong>Patients with definite ARVC, no prior sustained VA, and contrast-enhanced cardiac magnetic resonance at baseline were followed at 17 centers. Survival analyses were performed to assess LV LGE effect on VA prediction, and its incremental prognostic value on the risk calculator was evaluated using Cox proportional hazard models. The presence of high-risk LGE, defined as LV epicardial, transmural, or combined septal and free-wall LGE, was studied as a sensitivity analysis.</p><p><strong>Results: </strong>Of 385 patients (39.6±15.4 years, 39.7% male, 54.0% probands), 132 (34.3%) had LV LGE on cardiac magnetic resonance, with 98 (25.5%) having a high-risk pattern. Over 3.1 [1.2-5.8] years of follow-up, 67 (17.4%) patients experienced VA. In univariable analysis, both LV LGE (hazard ratio, 1.82; <i>P</i>=0.014) and high-risk LV LGE (hazard ratio, 1.85; <i>P</i>=0.017) were associated with higher risk for VA. However, after adjusting for the ARVC calculator-estimated risk, the presence of neither LV LGE (<i>P</i>=0.85) nor high-risk LV LGE (<i>P</i>=0.87) independently predicted sustained VA. (graphic abstract).</p><p><strong>Conclusions: </strong>While associated with the risk of VA in ARVC, LV LGE did not provide incremental prognostic value for incident VA risk prediction compared with the ARVC risk calculator.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":"19 2","pages":"e014265"},"PeriodicalIF":9.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146212362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultra-Low Cryoablation for Scar-Related VT Ablation: Results From the US Early Feasibility Study.","authors":"J Peter Weiss, Vivek Y Reddy, Harikrishna Tandri, Travis D Richardson, Edward P Gerstenfeld, William G Stevenson, Nabil Jubran, Ilya Grigorov, Roderick Tung","doi":"10.1161/CIRCEP.125.014095","DOIUrl":"10.1161/CIRCEP.125.014095","url":null,"abstract":"<p><strong>Background: </strong>A limitation of ablation for scar-related ventricular tachycardia (VT) is insufficient lesion depth to address nonendocardial substrate. Ultra-low temperature cryoablation (ULTC) at -196°C has been shown to create transmural lesions in preclinical models. Early human studies in Europe have shown safety and efficacy.</p><p><strong>Methods: </strong>An EFS (Early Feasibility Study) was designed in collaboration with the Food and Drug Administration as a prospective, nonrandomized evaluation of the acute safety and effectiveness of ULTC ablation for scar-related VT.</p><p><strong>Results: </strong>Twenty patients (age 63±14 years; 5% women; LVEF 36±13%; 45% ischemic and 55% nonischemic) underwent VT ablation with ULTC from September to December 2023 at 4 clinical sites. Ablation strategies included substrate modification during sinus rhythm, as well as activation and entrainment mapping when hemodynamics permitted. Mean ULTC lesions were 9.9±3.6, with a total freeze duration of 47±22 minutes. Noninducibility of the targeted VTs was observed in 13 of 14 patients with inducibility tested both pre- and postablation. There were no procedural strokes, tamponades, or deaths. One suspected cardiac perforation without tamponade was conservatively managed. One patient was excluded from the follow-up efficacy analysis due to RF use, and another lacked postacute follow-up due to death from heart failure 1 month post-procedure. Among surviving per-protocol patients, 23.7±4.3 weeks of freedom from VT and implantable cardioverter defibrillator shock were 61.1% (11/18) and 83.3% (15/18), respectively.</p><p><strong>Conclusions: </strong>In a US EFS, ULTC therapy was safe and effective for the treatment of scar-related VT. The EFS design, in collaboration with the Food and Drug Administration, represents an important initiative to accelerate the evaluation of new medical technologies in the United States.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT05675865.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e014095"},"PeriodicalIF":9.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146099806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}