{"title":"A rare presentation of essential thrombocytosis masked as vasculitis","authors":"Vikram Muralidhar Haridas, K. Haridas","doi":"10.15305/ijrci/v12i1/213","DOIUrl":"https://doi.org/10.15305/ijrci/v12i1/213","url":null,"abstract":"This case study presents the clinical journey of a 37-year-old woman who previously experienced gangrene in her fingers and toes. Initial assessments revealed elevated total white blood cell count and platelets, coupled with low hemoglobin levels. Despite normal inflammatory markers and negative results for antiphospholipid syndrome, antinuclear antibodies, and anti-neutrophil cytoplasmic antibodies, arterial Doppler imaging displayed no abnormalities. Suspecting vasculitis, the patient was initially treated with steroids and aspirin. However, subsequent investigations revealed essential thrombocytosis, a myeloproliferative disorder, confirmed by a positive JAK2 gene mutation. This case underscores the complexity of diagnosing rare hematological disorders and the importance of comprehensive evaluations for accurate treatment strategies. ","PeriodicalId":102906,"journal":{"name":"Internet Journal of Rheumatology and Clinical Immunology","volume":"101 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141667215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amulya T M, G. N. Devi, M. Mamadapur, Varuni Pragya
{"title":"ENT manifestations of Sjogren's syndrome: A narrative review","authors":"Amulya T M, G. N. Devi, M. Mamadapur, Varuni Pragya","doi":"10.15305/ijrci/v12i1/387","DOIUrl":"https://doi.org/10.15305/ijrci/v12i1/387","url":null,"abstract":"","PeriodicalId":102906,"journal":{"name":"Internet Journal of Rheumatology and Clinical Immunology","volume":"319 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140233067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Wilson’s disease with anti-CCP positive rheumatoid arthritis: A rare co-existence","authors":"V. Haridas, K. Haridas","doi":"10.15305/ijrci/v11i1/340","DOIUrl":"https://doi.org/10.15305/ijrci/v11i1/340","url":null,"abstract":"","PeriodicalId":102906,"journal":{"name":"Internet Journal of Rheumatology and Clinical Immunology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115572654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veena Ramachandran, Chandrashekara S, Devaraj Kori, P. J. Haridas, K. Haridas
{"title":"Hyperinflammatory syndrome: Two viruses, similar story","authors":"Veena Ramachandran, Chandrashekara S, Devaraj Kori, P. J. Haridas, K. Haridas","doi":"10.15305/ijrci/v11i1/377","DOIUrl":"https://doi.org/10.15305/ijrci/v11i1/377","url":null,"abstract":"","PeriodicalId":102906,"journal":{"name":"Internet Journal of Rheumatology and Clinical Immunology","volume":"176 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124346056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary: A rare co-occurrence of anti CCP-positive rheumatoid arthritis with sacroiliitis","authors":"Ankur Dalal","doi":"10.15305/ijrci/v8i1/324","DOIUrl":"https://doi.org/10.15305/ijrci/v8i1/324","url":null,"abstract":"Dear editor, I have read the case report titled, ‘A rare co-occurrence of anti CCP-positive rheumatoid arthritis with sacroiliitis’ written by Haridas et al. with great interest! 1 The authors have highlighted (though rare) the need to consider the involvement of sacroiliac joints (SIJs) in patients diagnosed with rheumatoid arthritis (RA), which can be considered as an atypical joint involvement of RA from their experience with this case. However, there certain clarifications are needed for the common readers, which I would like to highlight in this commentary.","PeriodicalId":102906,"journal":{"name":"Internet Journal of Rheumatology and Clinical Immunology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128182241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patterns of drug use and factors affecting adherence to medication in patients with rheumatoid arthritis: A prospective, observational, hospital- based study","authors":"P. Bharthi, V. Shobha, Anuradha Subramanya","doi":"10.15305/ijrci/v7i1/316","DOIUrl":"https://doi.org/10.15305/ijrci/v7i1/316","url":null,"abstract":"Introduction: RA affecting ~ 1% of the world population, is associated with high level of non-adherence in clinical practice. The adherence to RA treatment therapy is affected by multiple factors. The present study evaluated the factors affecting adherence to medications among RA patients. Methodology: The prospective study was conducted from April 2014 to March 2015. Male and female subjects, aged ≥18 years, and diagnosed with RA were included in the study. Demographic data, disease- and treatment-related data, adverse event profile and investigation data were obtained from all the participants. Adherence to medication of the subjects was measured using adherence questionnaire. All the subjects were followed up at one month and at the end of 6 months. McNemar’s test was used to analyse the difference in adherence from baseline to follow up. All the statistical analyses were performed using SPSS statistical software, version 17.0. Results: The study included 124 subjects, with a male to female ratio of 0.25:1, mean age of 45 years and RA duration of 5 years. Mono and combination drug therapies were used in 59.1% and 41.9% of the subjects respectively. Methotrexate was the most frequently used drug as a part of the regimen (82.3%). Among the subjects, 88 (71%) were found to be adherent. The comparison of various factors revealed significant difference only for the duration of RA (P 0.04). Conclusion: The adherence to antirheumatic medications among RA patients remains moderate and factors such as rural residence and older age (>45 years) can be associated with good adherence to RA medication. The study also corroborates the previous literature evidence suggesting methotrexate as the commonly used drug for managing RA.","PeriodicalId":102906,"journal":{"name":"Internet Journal of Rheumatology and Clinical Immunology","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125822322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Managing chikungunya arthritis using etanercept","authors":"V. Haridas, K. Haridas","doi":"10.15305/IJRCI/V7I1/307","DOIUrl":"https://doi.org/10.15305/IJRCI/V7I1/307","url":null,"abstract":"Chikungunya virus or Aedes-borne alpha virus causes infection through an acute viremic phase and a chronic arthritis phase. The present study highlights the benefits of using etanercept for managing chikungunya arthritis, especially in scenarios where NSAIDS and steroids are contraindicated due to multiple comorbidities.","PeriodicalId":102906,"journal":{"name":"Internet Journal of Rheumatology and Clinical Immunology","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115833107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shivaputrappa Ghanti, S. Chandrashekara, B. Raj, Devaraj Kori, Ramkrishna Giri
{"title":"Acute lung involvement in RA is not always ILD","authors":"Shivaputrappa Ghanti, S. Chandrashekara, B. Raj, Devaraj Kori, Ramkrishna Giri","doi":"10.15305/IJRCI/V7I1/291","DOIUrl":"https://doi.org/10.15305/IJRCI/V7I1/291","url":null,"abstract":"Rheumatoid arthritis is a systemic inflammatory disorder with diverse extra-articular manifestations including vasculitis, lung disease, inflammatory eye disease and subcutaneous nodule formation. Among these manifestations, lung disease has been identified as a primary contributor of morbidity and mortality. The predominance of non-specific interstitial pneumonia pattern has been observed in most forms of connective tissue-associated ILD. Studies have demonstrated that the usual interstitial pneumonia (UIP) pattern is more prevalent among patients with RA-associated ILD. The extra-articular manifestations have been noted in nearly 50% of the patients, and the lung involvement in majority of the cases.8, 9 This study details the occurrence of lung involvement of viral etiology in RA, which could be misdiagnosed as RA-associated ILD.","PeriodicalId":102906,"journal":{"name":"Internet Journal of Rheumatology and Clinical Immunology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131448778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Venous malformation of lower limb with hypertrophy of limb, early terminalization of hair and hyperhidrosis","authors":"M. Gupta, Rajni Sharma, G. Tegta, Archit Gupta","doi":"10.15305/IJRCI/V7I1/305","DOIUrl":"https://doi.org/10.15305/IJRCI/V7I1/305","url":null,"abstract":"Vascular anomalies are the commonest developmental disorders. Venous malformations (VM) result due to dysmorphogenesis in the development of veins. Most commonly these disorders are localized to skin and subcutaneous tissue. Deeper venous malformation may affect the underlying muscle, bone and joints. Early terminalization of hair and increased sweating in VM plaque has been rarely reported. The present study deals with the case of a 15-year-old boy who had VM involving skin, subcutaneous tissue and bones with terminal hair and increased sweating over the plaque. Radiological examination showed bone hypertrophy with slow flow channels and phleboliths due to superficial and deep VM. He was treated with ethanol sclerotherapy.","PeriodicalId":102906,"journal":{"name":"Internet Journal of Rheumatology and Clinical Immunology","volume":"309 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134041299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}