{"title":"Reply to Cavill","authors":"Y. Daniel","doi":"10.1111/J.1365-2257.2004.00624.X","DOIUrl":"https://doi.org/10.1111/J.1365-2257.2004.00624.X","url":null,"abstract":"","PeriodicalId":10285,"journal":{"name":"Clinical and laboratory haematology","volume":"22 1","pages":"307-307"},"PeriodicalIF":0.0,"publicationDate":"2004-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78589988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reference values for the activated partial thromboplastin time in infants using a synthetic reagent.","authors":"A M Conway, R F Hinchliffe, A Finn, F Bell","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10285,"journal":{"name":"Clinical and laboratory haematology","volume":"21 6","pages":"427-8"},"PeriodicalIF":0.0,"publicationDate":"1999-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21554884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of idiopathic hypereosinophilic syndrome with hypersegmented and hypogranular eosinophils.","authors":"H J Kim, Y J Lee, D S Lee, H I Cho","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10285,"journal":{"name":"Clinical and laboratory haematology","volume":"21 6","pages":"428-30"},"PeriodicalIF":0.0,"publicationDate":"1999-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21554888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reference intervals for haematological parameters in urban school children and adolescents.","authors":"Z Flegar-Mestrić, A Nazor, N Jagarinec","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10285,"journal":{"name":"Clinical and laboratory haematology","volume":"21 1","pages":"72-4"},"PeriodicalIF":0.0,"publicationDate":"1999-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21068869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. G. Martin, K. Sukhu, E. Chambers, P. Giangrande
{"title":"Evaluation of a novel ELISA screening test for detection of factor VIII inhibitory antibodies in haemophiliacs.","authors":"P. G. Martin, K. Sukhu, E. Chambers, P. Giangrande","doi":"10.1097/00001721-199811000-00035","DOIUrl":"https://doi.org/10.1097/00001721-199811000-00035","url":null,"abstract":"Treatment of patients with haemophilia A with coagulation factor concentrates may result in the development of inhibitory antibodies directed against factor VIII (FVIII). In this study, a previously unpublished ELISA test for FVIII inhibitor screening (Genetic Testing Institute [GTI] FVIII inhibitor, Brookfield, WI, USA) was evaluated in 131 blood samples (124 samples from patients with haemophilia A, and seven serial samples from one patient with an acquired FVIII inhibitor). Comparisons were made with the routine screening assay (based on recovery of FVIII) and confirmed where positive (< 90% recovery) with the New Oxford assay. The ELISA kit had a sensitivity of 97.7% and specificity of 78.4%. The high negative predictive value of this new test (98.6%) suggests it may be useful as a reliable, rapid (< 2 h) and flexible (microwell strip format) tool for inhibitor screening of samples from both patients with haemophilia A and those with suspected acquired FVIII inhibitors.","PeriodicalId":10285,"journal":{"name":"Clinical and laboratory haematology","volume":"113 1","pages":"125-8"},"PeriodicalIF":0.0,"publicationDate":"1998-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78951331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Guidelines for the clinical use of blood cell separators. Joint Working Party of the Transfusion and Clinical Haematology Task Forces of the British Committee for Standards in Haematology.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>These Guidelines outline standards of care for the clinical use of cell separators for both patients and donors.</p>","PeriodicalId":10285,"journal":{"name":"Clinical and laboratory haematology","volume":"20 5","pages":"265-78"},"PeriodicalIF":0.0,"publicationDate":"1998-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20718661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The laboratory diagnosis of malaria.","authors":"R W Girdwood, H V Smith","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10285,"journal":{"name":"Clinical and laboratory haematology","volume":"20 5","pages":"322"},"PeriodicalIF":0.0,"publicationDate":"1998-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20719192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Haematologists in district general hospitals practise evidence based medicine.","authors":"M Galloway, G Baird, A Lennard","doi":"10.1046/j.1365-2257.1997.00077.x","DOIUrl":"https://doi.org/10.1046/j.1365-2257.1997.00077.x","url":null,"abstract":"<p><p>A study published by the Centre for Evidence Based Medicine in Oxford, demonstrated that 82% of primary interventions offered by a general medical team in a 1 month period were evidence based. This contrasted with the traditional view that only 10-20% of medical interventions offered to patients have any scientific foundation. We have carried out a prospective study to determine if the primary interventions we offer to patients are evidence based. In June 1996 all therapeutic decisions which were made in one clinical haematology practice were studied. We included in the analysis the primary haematological diagnosis and the primary intervention offered. Interventions were classified as evidence based if the intervention was based on either evidence from randomized controlled trials, or evidence from well-designed non-randomized prospective or retrospective controlled studies or other convincing non-experimental evidence. In our study 70% of the primary therapeutic decisions made in the 83 patients studied were evidence based. This study reinforces the view that earlier assessments of the degree to which medicine is evidence based were too pessimistic. It is clear from our study that randomized controlled trials need to be developed in areas which are a relatively common clinical problem.</p>","PeriodicalId":10285,"journal":{"name":"Clinical and laboratory haematology","volume":"19 4","pages":"243-8"},"PeriodicalIF":0.0,"publicationDate":"1997-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1046/j.1365-2257.1997.00077.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20387025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}