Nigerian Journal of Chemical Research最新文献

{"title":"Phytochemical Contents and In Vitro Pathogenic Microbial Growth Inhibitory Activities of Acanthus montanus Root and Leaf Extracts","authors":"G. Ndukwe, O. F. Okoronkwo, I. R. Jack","doi":"10.4314/njcr.v28i2.5","DOIUrl":"https://doi.org/10.4314/njcr.v28i2.5","url":null,"abstract":"The study was directed at extraction, bioactivity analysis and ascertaining phytochemical composition of the leaf and root extracts of Acanthus montanus. Acanthus montanus (Acanthaceae family) is a shrub that is popularly grown in tropical countries of the world. The plant materials were harvested from Choba community in Rivers State, Nigeria. Extracts of Acanthus montanus (28.3, 19.45 and 25.5 g of n-hexane, ethylacetate and ethanol leaf extracts; and 3.45, 11.32 and 12.44 g of n-hexane, ethylacetate and ethanol root extracts respectively) were obtained through sequential maceration and were separately subjected to in vitro bioassay against a wide range of pathogenic microbes using the agar well diffusion method. Fifteen microorganisms were employed in the investigation, eight bacteria which included Salmonella typhi, Salmonella paratyphi, Pseudomonas aeruginosa, Shigella sonniea, Shigella dysentariae, Escherichia coli, Staphylococcus aureus, Staphylococcus pyogenes and seven fungi which included Candida albicans, Sacharomyces cerevisiae, Rhizopus eligastus, Aspergillus flavus, Aspergillus fumigates, Fusa equisetti and Aspergillus niger. The crude extracts exhibited high microbial growth inhibitory activities with zones of inhibition which ranged between 14 and 34 mm, though there was moderate (19 mm zone of inhibition), or no activity observed for the n-hexane leaf and root extracts. All test organisms were sensitive to the extracts. Standard analytical methods and Gas Chromatography - Flame Ionization Detector (GC-FID) were used for analysis and quantification of the phytochemicals present in the extracts. Major phytochemical contents of the leaf and root extracts included flavonoids (86% - 52.66%), alkaloids (10.66% - 3.25%) and other phenolic compounds (20.52% - 6.38%). In conclusion, the leaf and root extracts of Acanthus montanus are broad-spectrum antimicrobial agents also rich in flavonoids.","PeriodicalId":102130,"journal":{"name":"Nigerian Journal of Chemical Research","volume":"57 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139451501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Bioactive Agents in Calotropis Procera Plant Parts Through Anti-Microbial, Proximate, and Antioxidant Studies.","authors":"C. Ogwuche, O. Odeja","doi":"10.4314/njcr.v28i2.4","DOIUrl":"https://doi.org/10.4314/njcr.v28i2.4","url":null,"abstract":"Successive extraction of the aerial plant parts of Calotropis procera using soxhlet extraction yielded the phytochemicals; saponins, alkaloid, tannins, phenol, flavonoids, anthraquinones, and glycosides. Bioassay analysis using standard procedures like Mueller Hinton dilution experiment, demonstrated antibacterial potentials against microbes. E. coli, C. albicans, S. aureus, S. pyogenes, P. aeruginosa, S. typhi, and C. stellatoidea. 27 mm to 41 mm indicated  zones of inhibition range. The MBC and MFC for all the microorganisms were at 25 mg/ml except for S. pyogenes which was at 12.5 mg/ml. The MIC for the most sensitive organisms was 12.5 mg/ml with the exception of P. aeruginosa and S. pyogenes which had theirs at 6.25 mg/ml. Proximate analysis used standard AOAC method, and in antioxidant analysis, free radical scavenging method of 2, 2-diphenyl-1-picryl-hydrazyl (DPPH) were employed. The results are as follows, proximate analysis revealed the percentage contents of fat, crude fiber, protein, ash, and carbohydrates to be 2.93, 7.05, 1.68, 56.50, and 18.69, respectively. In the antioxidant studies, free radical scavenging technique employing 2, 2-diphenyl-1-picryl-hydrazyl (DPPH) was used. Samples and standards were determined using the IC50. The active sample was hexane extract, with an IC50 of 0.0878, followed by ethyl acetate (0.8811) and methanol (0.9215).","PeriodicalId":102130,"journal":{"name":"Nigerian Journal of Chemical Research","volume":"32 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139457663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation into the Bioavailability of Some Essential Health Based Elements in Ripe and Unripe Noni Fruits (Morinda citrifolia)","authors":"S. A. Shettima, B. A. Baffa, A. A. Baffa, A. Akinlabi, A. S. Abdulkadir","doi":"10.4314/njcr.v28i2.2","DOIUrl":"https://doi.org/10.4314/njcr.v28i2.2","url":null,"abstract":"Noni (Morinda citrifolia) fruit has recently been gaining attention in the area of nutraceutical research due to its potential health benefits. The Fruit of the morinda citrifolia plant, also known as Indian mulberry, has been used for medicinal purposes for centuries in Polynesia and Southeast Asia and recently in Africa. The fruit has gained significant attention for its profound therapeutic and nutritional benefits in treating various ailments. This study aims to contribute to the existing literature by analyzing the presence and quantity of selected elements relevant to human health, namely Calcium, Manganese, Potassium, Phosphorus, Sodium, Nickel, Mercury, Lead, Arsenic, Chromium, and Cadmium, in both ripe and unripe Noni fruits. The highly sensitive atomic absorption spectroscopic (AAS) technique was employed for this purpose. The results revealed that ripe Noni fruit contained higher concentrations of Calcium, Potassium, Chromium, and Phosphorus, while unripe Noni fruit had higher levels of Manganese, Sodium, and Nickel.","PeriodicalId":102130,"journal":{"name":"Nigerian Journal of Chemical Research","volume":"116 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139453778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization, Efffects and Chemical Treatment of Heavy Metals in Produced Water from Injection Wells using Hydroxide Precipitation","authors":"T. N. Chikwe, E. C. Igwe","doi":"10.4314/njcr.v28i2.1","DOIUrl":"https://doi.org/10.4314/njcr.v28i2.1","url":null,"abstract":"Produced water obtained from five (5) water injection Wells in the Niger Delta area Nigeria were analysed for heavy metal ion concentrations using Themo Elemental Flame Atomic Absorption Spectrophotometer (AAS). Results obtained show that concentrations of lead (Pb2+), cadmium (Cd2+), chromium (Cr2+), nickel (Ni2+), cobalt (Co2+), vanadium (V2+), zinc (ZN2+), mercury (Hg+), silver (Ag+) and copper (Cu2) were above acceptable limits as specified by Environmental Guidelines and Standard for Petroleum Industries in Nigeria (EGASPIN). The concentrations of As2+, Fe2+, K+ and Mn2+ were within specification. Commingled produced water from the five water injection Wells were subjected to hydroxide precipitation using Ca(OH)2 at concentrations of 10, 20, 30, 40 and 50 ppm respectively. Results obtained show that all the heavy metal ions reduced within acceptable limit at 30 ppm chemical concentration. Heavy metal ions reduced with increase in chemical concentration with a corresponding increase in the pH of the solution which was however still within specification. The hydroxide converts the metal ions dissolved in solution into solid particles for easy sedimentation. Ca(OH)2 precipitates metal ions by changing the pH and electro-oxidizing potential of the solution. Properly treated produced water can be reinjected into the reservoir to enhance oil recovery, used in agriculture for irrigation purposes, discharged into the sea and other water bodies during offshore operations or even used in drilling services. Produced water discharged into the soil are non-biodegradable so must be adequately treated before discharge. Plants pick up heavy metals through their roots by the release of a variety of root exudates which changes the rhizosphere pH of the metal ion in solution thereby making them bioavailable for plant uptake by osmosis. Heavy metals in plants can exert a variety of toxic actions by damaging plant chloroplast thereby disturbing photosynthesis. Humans take in heavy metals into their system by consuming contaminated plants, water as well as inhaling contaminated air. Consumption, ingestion and inhalation of heavy metals by humans can cause a wide range of ailments such as cardiovascular diseases, kidney related problems, neurocognitive diseases, renal damage, heart disease, coronary artery disease, lung fibrosis, nasal cancer.","PeriodicalId":102130,"journal":{"name":"Nigerian Journal of Chemical Research","volume":"28 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139456037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of the Physico-Chemical Properties and Trace Metal Content of Palm Oil, from Selected Markets in Jos South and Jos North LGA, Plateau State, Nigeria.","authors":"J. R. Gungshik, M. Ibrahim, O. A. Onyemowo, L. A. Rabiat","doi":"10.4314/njcr.v28i2.3","DOIUrl":"https://doi.org/10.4314/njcr.v28i2.3","url":null,"abstract":"The quality of palm oil samples collected from three different markets in Jos South and Jos North Local Government Area of Plateau State were analyzed and evaluated using standard analytical laboratory procedures. The relative ranges of the physicochemical values obtained were as follows; Moisture Content (MC): 0.56 - 1.89, Iodine value (IV); 51.88 - 55.57 g I2/100g, Peroxide Value (PV): 0.98 - 4.16 mEq02/kg, Saponification Values (SV): 198.46 - 201.54 mgKOH/g, Acid Value (AV): 9.93 - 57.65, and Refractive Index (RI), 1.4576 - 1.4580. The moisture content, iodin value, pH values and acid values were found to exceed the Standard Organization of Nigeria (SON) permissible limits of moisture content (0.29 mgKOH/g), iodine value (45 - 53 mg I2/100g), pH (5 - 7 mg/L), and acid value (0.7 max mg/L) for edible oils respectively while the refractive index, saponification values, peroxide values falls within the SON allowable limits of refractive index (1.4612-1.4707 mg/L), saponification value (195-205 mgKOH/g) and peroxide value (10 mEq02/kg) respectively . The amounts of trace metals (Cu, Zn, Fe, Pb and Cd) determined in the palm oil using the atomic absorption spectrophotometer ranged from Cu(0.34 - 0.52 mg/l), Zn(1.58 - 2.33 mg/l), Fe(19.18 - 26.74 mg/l), Pb(2.87 - 4.06 mg/l) and Cd(1.58 - 2.24 mg/l). However, the levels of Zn, Fe, Pb and Cd exceeded the WHO/FAO recommended values of (1.50, 1.00, 0.05 and 0.02 mg/L) respectively while only Cu concentration was below the WHO/FAO limits of 2.00 mg/L for trace metals in edible palm oil. Consequently, the results of this study shows that the palm oil consumed from these selected markets does not meet the standard quality specification for edible palm oils and hence can post significant health threat to consumers. Therefore, food regulatory agencies should strengthen their surveillance to promote food and health safety of the populace.","PeriodicalId":102130,"journal":{"name":"Nigerian Journal of Chemical Research","volume":"26 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139458147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-Hyperglycemic and Antioxidant Potentials of Some Bioactive Compounds Identified From The Methanolic Kernel Extract of Anacadium ocidentale in vitro and in silico Investigations","authors":"S A Ahmed, A T Ajiboye, Y A Ibrahim, A T Olagunju, S Salau, O Adetunji","doi":"10.4314/njcr.v27i1.7","DOIUrl":"https://doi.org/10.4314/njcr.v27i1.7","url":null,"abstract":"The phytochemical components of roasted kernel of cashew nut (Anacadium ocidentale), its antioxidant and anti-hyperglycemic potentials were investigated via in vitro and in silico. The roasted kernel of cashew nut was extracted in 95 % methanol. Using boron trifloride (10 % in 1-butanol), the extract was derivatized and the derivatized sample was analyzed using a Gas Chromatographic–Mass Spectrometry (GC-MS) method to establish its chemical constituents. Antioxidant potential was evaluated through 2, 2-diphenyl-1-picrylhydrazyl (DPPH•) and 2,2′-azino-bis-(3-ethyl benzothiazoline-6-sulphonic acid) (ABTS•+) radical scavenging assays. The anti-hyperglycemic potential of the crude methanol extract was investigated through α-glucosidase assay. The results of phytochemical screening revealed the presence of phytochemicals such as phenols, glycosides, alkaloids, steroids, carbohydrate, flavonoids and terpenoids. Total numbers of 20 phytochemicals belonging to different classes of natural products were identified by GC-MS analysis. Carbonic acid, dodecyl vinyl ester (45.9 %) was found to be the major compound. Other compounds like N- serylserine, D- fructose, 3-0-methyl, β- Amyrone, β- Amyrin, Lupeol and 9- octadecenoic acid were also identified. The methanol extract of roasted cashew kernel showed highest DPPH scavenging activity (IC50 10 ± 0.001 µg/mL) which is statistically similar to positive controls, vitamin C and rutin (IC50 = 4 ± 0.001 and 1 ± 0.0001 µg/mL) and also exhibited moderate ABTS scavenging activity (IC50 = 14 ± 0.001 µg/mL) which is statistically significant as compared to positive controls, vitamin C (IC50 = 13 ± 0.01 µg/mL) and rutin (IC50 = 16 ± 0.001 µg/mL) respectively. The result of enzyme inhibition assay showed that the extract possesses highest anti-hyperglycemic potential against α-glucosidase with IC50 value (0.00024 ± 0.00002 µg/mL) compared to standard drug acarbose (IC50 = 0.417 ±0.021 µg/mL). The in silico techniques comprising the molecular docking, bioactivity and toxicity studies provides insight into the inhibitory properties, structure-activity-relationship predictions and drug-likeliness activities of the identified compounds. The research reveals the bioactive components present in the roasted kernel of cashew nut that can be utilized for its antioxidant and anti-hyperglycemic properties. Hence consumption of roasted cashew kernel could be beneficial for the treatment of diabetes mellitus and prevention of oxidative stress-related degenerative disorders","PeriodicalId":102130,"journal":{"name":"Nigerian Journal of Chemical Research","volume":"175 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135656040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soil Amendment With Biochar Blend Produced From Selected Waste","authors":"M O Ekebafe, I O Ekebafe, P T Ikyaahemba","doi":"10.4314/njcr.v27i1.5","DOIUrl":"https://doi.org/10.4314/njcr.v27i1.5","url":null,"abstract":"Agricultural performance of biochar blend prepared from waste on the properties of soil supporting the oil palm was investigated. The biochar from the waste produced from coconut coir and chicken dung at 300oC for three hours were characterized in terms of pH, attrition, porosity, bulk density, ash content, conductivity, surface charge, nutrient value, yield% and surface area. Soil samples collected at the Nigeria Institute for Oil Palm Research (NIFOR) main station were prepared and analyzed for physico-chemical properties in the laboratory using standard techniques. The physico-chemical properties of the biochar blend –soil mixture samples in which sprouted oil palm seedlets have been planted were measured as a function of biochar blend and loading and compared with the values obtained in the control without biochar. The biochar blend showed significant (p<0.05) improvement in soil properties and growth of the oil palm seedlets.","PeriodicalId":102130,"journal":{"name":"Nigerian Journal of Chemical Research","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135756621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amino Acid Profile of the Oil Seed of Guizotia scabra Harvested From Plateau and Kaduna States – Nigeria","authors":"P A Chomo, R M Okunola, S S Suleiman","doi":"10.4314/njcr.v27i1.6","DOIUrl":"https://doi.org/10.4314/njcr.v27i1.6","url":null,"abstract":"Guizotia scabra (L.F cass. composite) is an oil seed crop found wildly and in some areas cultivated at middle and higher elevations in Nigeria and other African countries. The medicinal importance attached to the plant and the acceptance of the seed in some of our rural areas for preparing different types of delicacies is the driving force of this research. The objectives of this study were to determine the amino acids profile. PTH Amino acid analyser was used to determine amino acids in the sample. Amino acid profile revealed that Glutamic acid in the sample from Plateau was 2.57 g/100g protein while Kaduna state was 3.14g/100g protein; arginine in the sample from Plateau was 1.72 g/100g protein while that from Kaduna was 2.06 g/100g protein. Leucine from Plateau was 1.69 g/100g protein while that of Kaduna was 2.10 g/100g protein; aspartic acid in the sample from Plateau was 1.55 g/100g protein while that of Kaduna was 1.80 g/100g protein. The sample from Plateau was 1.00-glycine per100 g protein while that of Kaduna was 1.17 g/100g protein, tyrosine in sample from Plateau was 0.52 g/100g protein while that of Kaduna was 0.34 g/100g protein, isoleucine in sample from Plateau was 0.49 g/100 g protein while that of Kaduna was 0.82 g/100g protein. In addition, Alanine in the sample from Plateau was 0.42 g/100 g protein while that of Kaduna was 0.53 g/100g protein as valine in the sample from Plateau was 0.41 g/100 g protein while that of Kaduna was 0.61 g/100g protein. The sample from Plateau has 0.41g proline per 100g protein while that of Kaduna was 0.51 g/100g protein. Glycine in the sample from Plateau was 0.38 g/100g protein while that of Kaduna was 0.50 g/100g protein, and phenylalanine in the sample from Plateau was 0.35 g/100g protein while that of Kaduna was 0.44 g/100g protein. The sample from Plateau has 0.24g cysteine per100g protein while that of Kaduna was 0.24 g/100g protein; threonine in the sample from Plateau was 0.19 g/100g protein while that of Kaduna was 0.28 g/100g protein. The sample from Plateau has 0.16g serine per g/100g protein while that of Kaduna was 0.22 g/100g protein. The concentration of tryptophan in the sample from Plateau was 0.16 g/100g protein while that of Kaduna was 0.23 g/100g protein and histidine in the sample from Plateau was 0.10 g/100g protein while that from Kaduna was 0.19 g/100g protein. The essential and non-essential amino acids from plateau state are 36.19% and 38.18% respectively while that from Kaduna state are 38.44% and 61.56% respectively. These therefore makes the seed a good source of protein and it is hereby recommended for the fortification of diets that are low in protein for both man and animals.","PeriodicalId":102130,"journal":{"name":"Nigerian Journal of Chemical Research","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135756625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GC-MS and Spectrophotometric Quantitative Phytochemical Analysis of Bioactive Phytochemicals in Ethylacetate Extract Of Leaves Of Ficus exasperata Vahl: A Further Evidence For Its Medicinal Diversity","authors":"R S Mohammed, F M Kntapo, B A Yagana, G Saidu, J O Abah","doi":"10.4314/njcr.v27i1.4","DOIUrl":"https://doi.org/10.4314/njcr.v27i1.4","url":null,"abstract":"The GC-MS and phytochemical analysis of ethylacetate leaves extract of Ficus Exasperata Vahl was carried out. GC-MS Analysis revealed 23 constituents in which they were all identified. The major constituents were three(3) compounds with percentage peak areas of 23.20%(1- Nonadecane), 15.88%(1-Pentadecane) and 11.48%(Behenic alcohol), other constituents less than ten percentage peak area are 4.51%(1-Dodecanol, 3.56%(2,5-cyclohexadiene-1,4-dione,2,6-bis(1,1-d), 5.17%( Isopropyl myristate), 4.27%(n-hexadecanoic acid), 6.49%(Behenic alcohol), 4.91%(Oleic acid), 4.25%(propanoic acid, decyl ester), 2.89%(Octacosanol), 3.07%( Bis(2-ethylhexyl)phthalate while other constituents were less than 2%. Spectroscopic quantitative phytochemical analysis of the Ethylacetate Extract of Leaves of Ficus Exasperata was found to contain 16.18mg/g (Alkaloids), 3.78mg/g (Steroids), 85.13mg/g (Flavonoids) and 268.18mg/g (Phenolics).","PeriodicalId":102130,"journal":{"name":"Nigerian Journal of Chemical Research","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135756627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gas Chromatography-Mass Spectroscopy(GC-MS) of Chloroform Extract of Ficus exasperata Vahl","authors":"R S Mohammed, B A Yagana, F M Kntapo, G Saidu, J O Abah, A Idris","doi":"10.4314/njcr.v27i1.2","DOIUrl":"https://doi.org/10.4314/njcr.v27i1.2","url":null,"abstract":"Gas Chromatography-Mass Spectrometry (GCMS) analysis of chloroform leaves extract of Ficus exasperate Vahl was performed to identify the composition and percentage abundance of the various phytochemical constituents of Ficus exasperate Vahl. The extract was obtained by fractionating methanol crude leave extract of Ficus exasperate Vahl with in order of increasing polarity, n-Hexane then chloroform. GC-MS analysis was carried out on a GC system comprising a Gas Chromatograph interfaced to a Mass Spectrometer (GC-MS) instrument. The components were compared with the database of spectrum of known components stored in the gas chromatography-mass spectrometry library. Gas Chromatography-Mass Spectrometry analysis of the chloroform leave extract of Ficus exasperate revealed the presence of acyclic olefin which is used for tanning oils and in synthetic fatty acids, Isopryl myristate used in cosmetics, Dibutyl phthalate which is used in cosmetics, textile, safety glass additive, oleic acid used in pharmaceuticals, Cyclopropanecarboxylic acid, 3-(2,2-dichlor used in agrochemicals and pharmaceuticals. The presence of these compounds justifies the use of some parts of the plant for various elements in folklore and can be advised as a plant of phytopharmaceutical and industrial importance.","PeriodicalId":102130,"journal":{"name":"Nigerian Journal of Chemical Research","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135756622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}