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Nihon saikingaku zasshi. Japanese journal of bacteriology最新文献

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[Flash Talk]. (Flash谈话)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2025-01-01 DOI: 10.3412/jsb.80.56
{"title":"[Flash Talk].","authors":"","doi":"10.3412/jsb.80.56","DOIUrl":"https://doi.org/10.3412/jsb.80.56","url":null,"abstract":"","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"80 2","pages":"56-85"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[pELF-type linear plasmids and antimicrobial resistance in enterococci]. [pelf型线性质粒与肠球菌耐药性]。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2025-01-01 DOI: 10.3412/jsb.80.197
Yusuke Hashimoto
{"title":"[pELF-type linear plasmids and antimicrobial resistance in enterococci].","authors":"Yusuke Hashimoto","doi":"10.3412/jsb.80.197","DOIUrl":"https://doi.org/10.3412/jsb.80.197","url":null,"abstract":"<p><p>Enterococci, particularly Enterococcus faecium, are major opportunistic pathogens, and the spread of multidrug-resistant strains, especially vancomycin-resistant enterococci (VRE), is a serious public health concern. Conjugative plasmids are key drivers of antimicrobial resistance gene (ARG) dissemination in enterococci. Until recently, all such plasmids were assumed to be circular. Here, we summarize our studies on pELF-type linear plasmids, a novel family of enterococcal plasmids.We first identified pELF1, a linear plasmid that carries both VanA- and VanM-type vancomycin resistance gene clusters and characterized its hybrid terminal structure and its ability to cross species barriers within the genus Enterococcus, thereby disseminating ARGs. In a documented episode of nosocomial VRE transmission, we then showed that a pELF-type linear plasmid (pELF2) mediated interspecies transfer of vancomycin resistance gene clusters among E. faecium, E. raffinosus, and E. casseliflavus.Using integrated molecular epidemiological, phenotypic, and transcriptomic analyses, we demonstrated that pELF-type linear plasmids are globally distributed as multiple lineages that retain a conserved backbone while adapting to their E. faecium hosts, functioning as major vehicles for ARGs in E. faecium. More recently, we showed that pELF-type linear plasmids have evolved through the acquisition of transposons and a circular plasmid carrying linezolid resistance genes, leading to strains with concomitant resistance to vancomycin and linezolid in both clinical and environmental settings.These findings indicate that pELF-type linear plasmids play a crucial role in the development of multidrug resistance in E. faecium and underscore the importance of incorporating this plasmid family into surveillance and intervention strategies aimed at limiting antimicrobial resistance.</p>","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"80 4","pages":"197-204"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145829427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Rab GTPase network-driven remodeling of membrane trafficking and intracellular bacterial dynamics during infection]. [Rab GTPase网络驱动的膜运输重塑和感染期间细胞内细菌动力学]。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2025-01-01 DOI: 10.3412/jsb.80.189
Takashi Nozawa
{"title":"[Rab GTPase network-driven remodeling of membrane trafficking and intracellular bacterial dynamics during infection].","authors":"Takashi Nozawa","doi":"10.3412/jsb.80.189","DOIUrl":"https://doi.org/10.3412/jsb.80.189","url":null,"abstract":"<p><p>Host cells remodel membrane trafficking pathways in response to microbial invasion as a self-defense strategy. Using an epithelial infection model of Group A Streptococcus (GAS), we have elucidated how Rab GTPase networks dynamically reorganize membrane trafficking to govern the intracellular fate of invading bacteria during infection. Our membrane dynamics analyses of selective autophagy (xenophagy) targeting cytosolic GAS revealed that multiple inter-organelle interactions mediated by an infection-specific Rab repertoire are crucial for antibacterial activity. While GAS-secreted NADase inhibits the canonical PI3P-dependent autophagy pathway, the host counters infection by activating an alternative PI4P-dependent xenophagy pathway through Rab-driven rewiring of membrane transport. Furthermore, our recent work has uncovered multilayered and stage-specific reprogramming of Rab networks during infection, including Rab41-mediated membrane repair and RabGAP1L-Rab11A-dependent bacterial expulsion.</p>","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"80 3","pages":"189-196"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145829464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Award Lecture]. (奖演讲)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2025-01-01 DOI: 10.3412/jsb.80.15
{"title":"[Award Lecture].","authors":"","doi":"10.3412/jsb.80.15","DOIUrl":"https://doi.org/10.3412/jsb.80.15","url":null,"abstract":"","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"80 2","pages":"15-16"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Special Lecture]. (特殊的演讲)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2025-01-01 DOI: 10.3412/jsb.80.17
{"title":"[Special Lecture].","authors":"","doi":"10.3412/jsb.80.17","DOIUrl":"https://doi.org/10.3412/jsb.80.17","url":null,"abstract":"","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"80 2","pages":"17"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Study on the pathogenic factors of pathogenic streptococci]. 【致病性链球菌致病因素研究】。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2025-01-01 DOI: 10.3412/jsb.80.175
Shigetada Kawabata
{"title":"[Study on the pathogenic factors of pathogenic streptococci].","authors":"Shigetada Kawabata","doi":"10.3412/jsb.80.175","DOIUrl":"https://doi.org/10.3412/jsb.80.175","url":null,"abstract":"<p><p>Streptococcus pyogenes infects the human pharynx, causing pharyngitis and tonsillitis, and as secondary complications, it can lead to acute glomerulonephritis and rheumatic fever. In recent years in Japan, there has been a trend of increasing cases of severe invasive streptococcal infections, which involve soft tissue necrosis, shock, and multiple organ failure. Streptococcus pneumoniae often resides in the nasal cavities of children, causing otitis media and pneumonia. In pneumonia among the elderly, it is frequently detected as a causative agent, and it has long been the case that more than half of the clinical isolates exhibit resistance to antibiotics. This overview discusses the responsible molecules and pathogenic mechanisms involved in these streptococcal infections.</p>","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"80 3","pages":"175-188"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145829462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[ICD]. (ICD)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2025-01-01 DOI: 10.3412/jsb.80.54
{"title":"[ICD].","authors":"","doi":"10.3412/jsb.80.54","DOIUrl":"https://doi.org/10.3412/jsb.80.54","url":null,"abstract":"","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"80 2","pages":"54-55"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Luncheon Seminar]. (午餐研讨会)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2025-01-01 DOI: 10.3412/jsb.80.173
{"title":"[Luncheon Seminar].","authors":"","doi":"10.3412/jsb.80.173","DOIUrl":"https://doi.org/10.3412/jsb.80.173","url":null,"abstract":"","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"80 2","pages":"173-174"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Symposium]. (研讨会)。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2025-01-01 DOI: 10.3412/jsb.80.18
{"title":"[Symposium].","authors":"","doi":"10.3412/jsb.80.18","DOIUrl":"https://doi.org/10.3412/jsb.80.18","url":null,"abstract":"","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"80 2","pages":"18-37"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Production and biological activity of the triazine derivatives: focusing on antibiotics produced by bacteria]. [三嗪类衍生物的生产和生物活性：以细菌生产的抗生素为重点]。
Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2025-01-01 DOI: 10.3412/jsb.80.1
Hajime Nakatani, Michio Homma
{"title":"[Production and biological activity of the triazine derivatives: focusing on antibiotics produced by bacteria].","authors":"Hajime Nakatani, Michio Homma","doi":"10.3412/jsb.80.1","DOIUrl":"10.3412/jsb.80.1","url":null,"abstract":"<p><p>Heterocyclic triazines and their derivatives have excellent biological activity and have been used as herbicides and anticancer drugs. A large number of derivatives were synthesized and their biological activity was investigated. Some bacteria synthesize the triazine derivatives such as Nostocine A, Toxoflavin, and Fluviol from GTP using enzymes similar to those in the synthesis pathway of Riboflavin (vitamin B2). These triazine derivatives show antibiotic activity. In particular, research on Toxoflavin has progressed as a toxin produced by bacteria that cause seedling rot and rice grain blight in rice. It has recently been revealed that Fluviol, which is produced by bacteria, acts to suppress the growth of pathogenic bacteria. This review will focus on triazine derivatives produced by bacteria.</p>","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"80 1","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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