Nihon saikingaku zasshi. Japanese journal of bacteriology最新文献

[Production and biological activity of the triazine derivatives: focusing on antibiotics produced by bacteria]. [三嗪类衍生物的生产和生物活性：以细菌生产的抗生素为重点]。

Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2025-01-01 DOI: 10.3412/jsb.80.1

Hajime Nakatani, Michio Homma

引用次数: 0

[Protein degradation in bacteria: focus on the ClpP protease]. [细菌中的蛋白质降解：聚焦 ClpP 蛋白酶】。］

Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2024-01-01 DOI: 10.3412/jsb.79.1

Fumihiro Ishikawa, Michio Homma, Genzoh Tanabe, Takayuki Uchihashi

引用次数: 0

[Population genetics of enterohemorrhagic Escherichia coli using whole-genome sequencing analyses]. [利用全基因组测序分析肠出血性大肠杆菌的群体遗传学]。

Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2024-01-01 DOI: 10.3412/jsb.79.283

Ken-Ichi Lee

引用次数: 0

[Development of next-generation antimicrobials with unique mechanisms of action]. [开发具有独特作用机制的新一代抗菌药物]。

Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2024-01-01 DOI: 10.3412/jsb.79.275

Hiroshi Hamamoto

引用次数: 0

[Rhodococcus equi infections in humans: an emerging zoonotic pathogen]. [人类感染马尾黄葡萄球菌：一种新出现的人畜共患病原体]。

Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2024-01-01 DOI: 10.3412/jsb.79.15

Shinji Takai, Yasutaka Mizuno, Yasunori Suzuki, Yukako Sasaki, Tsutomu Kakuda, Teruo Kirikae

{"title":"[Rhodococcus equi infections in humans: an emerging zoonotic pathogen].","authors":"Shinji Takai, Yasutaka Mizuno, Yasunori Suzuki, Yukako Sasaki, Tsutomu Kakuda, Teruo Kirikae","doi":"10.3412/jsb.79.15","DOIUrl":"https://doi.org/10.3412/jsb.79.15","url":null,"abstract":"Rhodococcus equi is a facultative intracellular gram-positive coccobacillus which is a well-known cause of foal pneumonia and/or enteritis in equine veterinary medicine. More than 300 cases of R. equi infection have been reported since the first description of human disease in 1968. Most patients who become infected with R equi are immunocompromised, such as those infected with human immunodeficiency virus (HIV), recipients of organ transplantation, and patients receiving cancer treatment. However, there are increasing reports of the immunocompetent hosts. The pathogenicity of R. equi has been attributed to the presence of plasmid-encoded virulence-associated proteins (Vap). To date, three host-associated virulence plasmid types of R. equi have been identified as follows: the circular pVAPA and pVAPB, related, respectively, to equine and porcine isolates in 1991 and 1995, and a recently described linear pVAPN plasmid associated with bovine and caprine strains in 2015. More recently, these three plasmid types have been re-found in the human isolates which were isolated during 1980s to 1990s. Not only horses, but also pigs, goats, cattle and their environment should be considered as a potential source of R. equi for humans. In this review, we shed light on the current understanding of R. equi as an emerging zoonotic pathogen.","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"79 1","pages":"15-24"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139935029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Mechanism of high-frequent horizontal gene transfer in Gram positive bacterial pathogens]. [革兰氏阳性细菌病原体中高频水平基因转移的机制]。

Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2023-01-01 DOI: 10.3412/jsb.78.179

Jun Kurushima

{"title":"[Mechanism of high-frequent horizontal gene transfer in Gram positive bacterial pathogens].","authors":"Jun Kurushima","doi":"10.3412/jsb.78.179","DOIUrl":"10.3412/jsb.78.179","url":null,"abstract":"Horizontal gene transfer through transconjugation and natural transformation plays a major role in the spread of antimicrobial resistance. Although the phenomenon of genetic element transmission has long been known, the rapid increase in the number of antimicrobial resistant bacteria in recent years and the accompanying accumulation of genomic information have revealed that horizontal gene transfer contributes to genome plasticity in various ways. The author reported the molecular mechanism of the antimicrobial activity of the accessory factor bacteriocin encoded by the junctional transfer plasmid of Enterococcus faecalis, a representative Gram-positive opportunistic pathogen that is concerned as highly antimicrobial resistant, and found diversity in the selfimmune system based on epidemiological studies. In addition, the author established a technique to visualize and quantify genomic recombination by natural transformation in Streptococcus pneumoniae which is also one of the most concerns for antimicrobial resistance and vaccine escape, at single cells level resolution in real time. Focuses on outcome from these research, this paper introduces the molecular mechanisms that promote horizontal gene transmission and the prospects for their technological application.","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"78 4","pages":"179-187"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139033151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Research on mechanisms of drug resistance and virulence expression in pathogenic Escherichia coli]. 【致病性大肠杆菌的耐药性和毒力表达机制研究】。

Nihon saikingaku zasshi. Japanese journal of bacteriology Pub Date : 2023-01-01 DOI: 10.3412/jsb.78.167

Hidetada Hirakawa

{"title":"[Research on mechanisms of drug resistance and virulence expression in pathogenic Escherichia coli].","authors":"Hidetada Hirakawa","doi":"10.3412/jsb.78.167","DOIUrl":"10.3412/jsb.78.167","url":null,"abstract":"Urinary tract infections (UTIs) are one of the most common infections. Uropathogenic Escherichia coli (UPEC) is the most common causative organism. Once UPEC enters the urinary tract, it infects the bladder and then ascends the urinary tract to the kidneys, where it causes pyelonephritis, a more severe form of the disease. While various virulence factors, including adhesions and cytotoxic factors to bladder epithelial cells, have been identified and their functions have been analyzed, the question remains, \"How can UPEC, which is harmless in the intestinal tract, be induced to become pathogenic in the urinary tract?\" and \"How does UPEC ascend the urinary tract and infect the kidneys?\" On the other hand, UPEC invades host cells and forms biofilm-like microcolonies that are resistant to various antimicrobial agents. We are working to solve this problem by identifying the factors responsible for the virulence of UPEC and the establishment of infection of the kidney, as well as the factors involved in microcolony formation and elucidating their functions. Here I outline the virulence expression of UPEC from bladder to kidney infection and the mechanism of UTI refractoriness, focusing on our studies.","PeriodicalId":101339,"journal":{"name":"Nihon saikingaku zasshi. Japanese journal of bacteriology","volume":"78 3","pages":"167-177"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50164299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0